La PitiÃ© SalpÃ©triÃ¨re Hospital Trials

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37 Trials

Active Trials

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Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Ratziu, Vlad

NATiV3, NCT04849728: A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( )

Recruiting

1000

Europe, Canada, US, RoW

IVA337, Lanifibranor, Placebo

Inventiva Pharma

NASH - Nonalcoholic Steatohepatitis

09/25

09/26

B-Well 2, NCT05630820 / 2022-002268-53: Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B

Active, not recruiting

871

Europe, Canada, Japan, US, RoW

Bepirovirsen, Placebo

GlaxoSmithKline, GlaxoSmithKline Research & Development Limited

Chronic Hepatitis B, Hepatitis B, Chronic

11/25

05/26

HORIZON, NCT05583344 / 2022-002538-14: Phase 2b Study of GSK4532990 in Adults With NASH

Active, not recruiting

284

Europe, Canada, Japan, US, RoW

GSK4532990, Placebo

GlaxoSmithKline, GlaxoSmithKline Research & Development Limited

Nonalcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver Disease

01/26

04/27

NCT06159257: Evaluation of the Physiological Stability Variability and Robustness of NIS4

Recruiting

N/A

Europe

Blood test

CerbaXpert

Evaluate the Physiological Stability of NIS4 Biomarker Between the Fed and Fasting State in Patients With the Target Condition (NAFLD)

12/24

09/25

M148, NCT06519331: Development of a New Method for Liver Stiffness Measurement Using FibroScan

Not yet recruiting

N/A

114

Europe

Research FibroScan (FS)

Echosens

Liver Diseases

10/26

05/27

DPAILO-1, NCT06344364: Digital Pathology and AI for Liver Outcomes in MASLD

Not yet recruiting

N/A

1800

Europe, RoW

Digital Pathology FibroNest Phenotypic Fibrosis Composite Score (Ph-FCS)

PharmaNest, Inc, Chinese University of Hong Kong, University of Edinburgh, University of Seville, Imperial College London, Icahn School of Medicine at Mount Sinai, Fundacio Clinic Barcelona, Sorbonne University, Newcastle University

Metabolic Dysfunction-associated Steatotic Liver Disease

05/25

07/25

BuleDelta, NCT04166266: National Cohort of Patients Co-infected with Hepatitis B and Delta Viruses

Recruiting

N/A

800

Europe

Blood draw for the laboratory assessment

ANRS, Emerging Infectious Diseases

Hepatitis D, Chronic, Hepatitis B, Chronic

12/27

06/28

FRAMES, NCT04925362: THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis)

Not yet recruiting

N/A

900

Biological specimens, Additional visit

Assistance Publique - Hôpitaux de Paris

NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Cirrhosis

06/36

NCT05479721: LITMUS Imaging Study

Active, not recruiting

N/A

450

Europe, US

University of Oxford, Newcastle University, University of Nottingham, University of Cambridge, University of Seville, Pinnacle Clinical Research, PLLC, ICAN Nutrition Education and Research, Assistance Publique - Hôpitaux de Paris, University of Angers, University of Palermo, University of Turin, Italy, University Medical Center Mainz, University of Helsinki, University of Bern, Linkoeping University, Perspectum, Antaros Medical, Resoundant Inc, Pfizer, Novartis, Takeda, Intercept Pharmaceuticals, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Boehringer Ingelheim

NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Liver, Steatosis of Liver

10/25

roux, christian h

NCT04829565: Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb

Recruiting

Europe

Botulinum toxin, Placebo

Centre Hospitalier Universitaire de Nice

Rhizarthrosis

05/25

08/25

ROC-SPA, NCT03445845: Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis

Completed

300

Europe, RoW

Secukinumab, TNF blocker, blood specimen

Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France

Axial Spondyloarthritis

09/24

10/24

SEQUENS-RA, NCT05428488: Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis

Recruiting

220

Europe, RoW

Abatacept (W12-W48), TNF Inhibitor (W12-W48), TNF Inhibitor (W0-W12)

University Hospital, Montpellier

Rheumatoid Arthritis

11/26

11/27

CRI-RA, NCT04870203: Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis

Recruiting

178

Europe, RoW

baricitinib treatment, anti-TNF therapy, Placebo

University Hospital, Bordeaux, Eli Lilly and Company, Biogen, Ministry for Health and Solidarity, France

Rheumatoid Arthritis

12/26

BACHELOR, NCT04027101: BAriCitinib Healing Effect in earLy pOlymyalgia Rheumatica

Completed

Europe

Baricitinib, Placebos

University Hospital, Brest, Eli Lilly and Company

Polymyalgia Rheumatic (PMR)

08/23

NCT05848258: An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

Recruiting

380

Europe, US, RoW

LY3871801, Placebo

Eli Lilly and Company, Rigel Pharmaceuticals

Rheumatoid Arthritis

02/26

07/26

ADIPENIGME, NCT05955976: Characteristics of Hoffa Adipose Tissue and Intramuscular Adipose Tissue in the Quadriceps Muscle

Recruiting

N/A

Europe

BIOPSY

Centre Hospitalier Universitaire de Nice

Osteo Arthritis Knee

09/23

03/24

OPPORTOS, NCT03570177: Fracture Prediction by Opportunistic Screening for Osteoporosis

Active, not recruiting

N/A

173720

Europe

Assistance Publique - Hôpitaux de Paris

Fractures Related to Skeleton Fragility

10/24

01/25

SAPHIR, NCT05598684: : Assessment of Predictive Factors for Persistence of Treatment After Initiation of Adalimumab With a Biosimilar (Adalimumab Fresenius KaBI or Substitution of Reference Adalimumab With the Fresenius Kabi Adalimumab Biosimilar in Patients With Chronic Inflammatory Diseases

Recruiting

N/A

600

Europe, RoW

Fresenius Kabi, France

Crohn Disease, Ulcerative Colitis, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis

09/25

12/25

FLEX, NCT05177549: Evaluation of Anterior Tibial Translation of the Knee in Healthy Women, at Two Times of the Menstrual Cycle, on Hormonal Contraceptives or Not

Recruiting

N/A

Europe

Bilateral knee examination with Lachmeter®

Centre Hospitalier Universitaire de Nice

Ligament; Laxity

06/24

02/25

TAGS, NCT06314191: Adipose Tissue and Symptomatic Gonarthrosis

Not yet recruiting

N/A

Europe

blood sampling, knee radiography

Centre Hospitalier Universitaire de Nice

Gonarthrosis, Obesity

06/25

11/25

Calprotectine, NCT05555433: in Spondyloarthritis

Recruiting

N/A

190

Europe

NO INTERVENTION

Centre Hospitalier Universitaire de Nice

Spondylarthritis

08/24

InCHO, NCT06347328: The Benefits of Posterior Joint Infiltration in Chronic Low Back Pain

Not yet recruiting

N/A

102

Europe

echo-guided infiltration, non-echo-guided infiltration

Centre Hospitalier Universitaire de Nice

Chronic Low-back Pain

01/27

03/27

MAJIK, NCT04602091: Observational Study in Patients Treated With JAK Inhibitors for Inflammatory Rheumatism

Recruiting

N/A

2300

Europe

no intervention

Societe Francaise de Rhumatologie, Bordeaux PharmacoEpi

Rheumatoid Arthritis, Inflammatory Rheumatism, Psoriatic Arthritis, Spondyloarthritis

06/26

06/30

INCREDIBLE, NCT06643845: Can Multimodal Medical Strategies Can Delay Total Knee Replacement?

Not yet recruiting

N/A

1000

Europe

arthroplasty, Medical and non-medical treatments

University Hospital, Brest

Osteoarthritis, Knee

07/30

EPROGE, NCT06466330: Efficacy of Microparticle Geniculate Artery Embolization in Total Knee Prosthesis Patients With Pain Resistant to Medical Treatment. A Prospective Randomized Controlled Trial

Recruiting

N/A

112

Europe

microparticles, embolization, sham embolization

Societe Francaise de Rhumatologie, Centre Hospitalier Universitaire de Nice, Euraxi Pharma

Knee Pain Chronic, Knee Pain Swelling

02/26

02/27

SMAP, NCT06059430: Cohort Project of Patients With Inflammatory Rheumatism

Not yet recruiting

N/A

1000

Europe

no intervention

Centre Hospitalier Universitaire de Nice

Rheumatoid Arthritis, Spondyloarthritis, Axial, Psoriatic Arthritis

09/43

12/43

NCT05593640: Thromboxane A2 and Osteoarthritis

Recruiting

N/A

Europe

biological samples

Centre Hospitalier Universitaire de Nice, French Society of Rheumatology

Osteoarthritis

09/23

REG-HYPO, NCT05596539: Prospective, Longitudinal, Observational Registry of Adult Patients with Hypophosphatasia

Recruiting

N/A

100

Europe

Data collection

Assistance Publique - Hôpitaux de Paris

Hypophosphatasia

03/25

03/31

NCT05592574: IL17 Rate and Spondyloarthritis

Recruiting

N/A

Europe

Blood sample

Centre Hospitalier Universitaire de Nice

Spondylarthritis

01/41

Zemouri, Sofia

FLUO, NCT05409612 / 2021-002691-39: Trial Assessing the Immunogenicity and Safety of Two Influenza Vaccine Strategies Among Severe Obese Adult Patients

Completed

206

Europe

Supemtek®, Vaxigriptetra®

Assistance Publique - Hôpitaux de Paris, Sanofi Pasteur, a Sanofi Company, Hospices Civils de Lyon

Morbid Obesity, Severe Obesity

04/23

10/23

OPPORTOS, NCT03570177: Fracture Prediction by Opportunistic Screening for Osteoporosis

Active, not recruiting

N/A

173720

Europe

Assistance Publique - Hôpitaux de Paris

Fractures Related to Skeleton Fragility

10/24

01/25

DAICAP, NCT05513820: Automatic Detection in MRI of Prostate Cancer:

Recruiting

N/A

1250

Europe

Assistance Publique - Hôpitaux de Paris, University Hospital, Strasbourg, France, University Hospital, Bordeaux, University Hospital, Lille, The Civil Hospitals, Lyon, Institut National de Recherche en Informatique et en Automatique, INCEPTO

Detection and Characterization of Prostate Cancer Based on Artificial Intelligence

12/24

TOOLBAR, NCT04941651: Efficacy of Telenutrition for the Treatment of Overweight Patients With Obesity and/or High Cardiometabolic Risk

Recruiting

N/A

346

Europe

OBE-COACH program, Connected devices, Connected Activity Tracer, e-learning program

Assistance Publique - Hôpitaux de Paris

Overweight and Obesity

11/25

11/26

Mathon, Bertrand

EPILITT, NCT05198882: Clinical Evaluation of Interstitial Laser Thermal Therapy Under Continuous MRI Monitoring as a Minimally Invasive Treatment of Patients With Medically Unbalanced Partial Epilepsy

Recruiting

Europe

Laser technology for intracerebral thermocoagulation

Assistance Publique - Hôpitaux de Paris, Medtronic

Drug-resistant Focal Epilepsy, Epilepsy, Epilepsies, Focal, Focal Epilepsy, Drug Resistant

09/23

08/24

SAPPHYRE, NCT04746625: Safety and Performance of the PolarisÂ® 24 Adjustable Valve System in Hydrocephalus Patients' Treatment

Recruiting

N/A

126

Europe

Sophysa

Hydrocephalus

06/24

06/28

OPSTIMVAG, NCT04693221: Optimization of the Parameters of Vagal Nerve Stimulation

Recruiting

N/A

140

Europe

Choice of VNS set of parameters based on the lowest PLI, EEG

Assistance Publique Hopitaux De Marseille

Epilepsy

06/25

12/26

MicroECoGG, NCT06408428: Glioma Intraoperative MicroElectroCorticoGraphy

Not yet recruiting

N/A

Europe

PANAXIUM MicroECoG

Institut National de la Santé Et de la Recherche Médicale, France, PANAXIUM

Glioma, Epilepsy

09/27

03/28

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Ratziu, Vlad

NATiV3, NCT04849728: A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( )

Recruiting

1000

Europe, Canada, US, RoW

IVA337, Lanifibranor, Placebo

Inventiva Pharma

NASH - Nonalcoholic Steatohepatitis

09/25

09/26

B-Well 2, NCT05630820 / 2022-002268-53: Study of Bepirovirsen in Nucleos(t)Ide Analogue-treated Participants With Chronic Hepatitis B

Active, not recruiting

871

Europe, Canada, Japan, US, RoW

Bepirovirsen, Placebo

GlaxoSmithKline, GlaxoSmithKline Research & Development Limited

Chronic Hepatitis B, Hepatitis B, Chronic

11/25

05/26

HORIZON, NCT05583344 / 2022-002538-14: Phase 2b Study of GSK4532990 in Adults With NASH

Active, not recruiting

284

Europe, Canada, Japan, US, RoW

GSK4532990, Placebo

GlaxoSmithKline, GlaxoSmithKline Research & Development Limited

Nonalcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver Disease

01/26

04/27

NCT06159257: Evaluation of the Physiological Stability Variability and Robustness of NIS4

Recruiting

N/A

Europe

Blood test

CerbaXpert

Evaluate the Physiological Stability of NIS4 Biomarker Between the Fed and Fasting State in Patients With the Target Condition (NAFLD)

12/24

09/25

M148, NCT06519331: Development of a New Method for Liver Stiffness Measurement Using FibroScan

Not yet recruiting

N/A

114

Europe

Research FibroScan (FS)

Echosens

Liver Diseases

10/26

05/27

DPAILO-1, NCT06344364: Digital Pathology and AI for Liver Outcomes in MASLD

Not yet recruiting

N/A

1800

Europe, RoW

Digital Pathology FibroNest Phenotypic Fibrosis Composite Score (Ph-FCS)

Metabolic Dysfunction-associated Steatotic Liver Disease

05/25

07/25

BuleDelta, NCT04166266: National Cohort of Patients Co-infected with Hepatitis B and Delta Viruses

Recruiting

N/A

800

Europe

Blood draw for the laboratory assessment

ANRS, Emerging Infectious Diseases

Hepatitis D, Chronic, Hepatitis B, Chronic

12/27

06/28

FRAMES, NCT04925362: THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis)

Not yet recruiting

N/A

900

Biological specimens, Additional visit

Assistance Publique - Hôpitaux de Paris

NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Cirrhosis

06/36

NCT05479721: LITMUS Imaging Study

Active, not recruiting

N/A

450

Europe, US

NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Liver, Steatosis of Liver

10/25

roux, christian h

NCT04829565: Assessment of Pain After Intra-articular Botulinum Toxin Injections in Carpometacarpal Osteoarthritis of the Thumb

Recruiting

Europe

Botulinum toxin, Placebo

Centre Hospitalier Universitaire de Nice

Rhizarthrosis

05/25

08/25

ROC-SPA, NCT03445845: Rotation or Change of Biotherapy After TNF Blocker Treatment Failure for Axial Spondyloarthritis

Completed

300

Europe, RoW

Secukinumab, TNF blocker, blood specimen

Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France

Axial Spondyloarthritis

09/24

10/24

SEQUENS-RA, NCT05428488: Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis

Recruiting

220

Europe, RoW

Abatacept (W12-W48), TNF Inhibitor (W12-W48), TNF Inhibitor (W0-W12)

University Hospital, Montpellier

Rheumatoid Arthritis

11/26

11/27

CRI-RA, NCT04870203: Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis

Recruiting

178

Europe, RoW

baricitinib treatment, anti-TNF therapy, Placebo

University Hospital, Bordeaux, Eli Lilly and Company, Biogen, Ministry for Health and Solidarity, France

Rheumatoid Arthritis

12/26

BACHELOR, NCT04027101: BAriCitinib Healing Effect in earLy pOlymyalgia Rheumatica

Completed

Europe

Baricitinib, Placebos

University Hospital, Brest, Eli Lilly and Company

Polymyalgia Rheumatic (PMR)

08/23

NCT05848258: An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

Recruiting

380

Europe, US, RoW

LY3871801, Placebo

Eli Lilly and Company, Rigel Pharmaceuticals

Rheumatoid Arthritis

02/26

07/26

ADIPENIGME, NCT05955976: Characteristics of Hoffa Adipose Tissue and Intramuscular Adipose Tissue in the Quadriceps Muscle

Recruiting

N/A

Europe

BIOPSY

Centre Hospitalier Universitaire de Nice

Osteo Arthritis Knee

09/23

03/24

OPPORTOS, NCT03570177: Fracture Prediction by Opportunistic Screening for Osteoporosis

Active, not recruiting

N/A

173720

Europe

Assistance Publique - Hôpitaux de Paris

Fractures Related to Skeleton Fragility

10/24

01/25

Recruiting

N/A

600

Europe, RoW

Fresenius Kabi, France

Crohn Disease, Ulcerative Colitis, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis

09/25

12/25

FLEX, NCT05177549: Evaluation of Anterior Tibial Translation of the Knee in Healthy Women, at Two Times of the Menstrual Cycle, on Hormonal Contraceptives or Not

Recruiting

N/A

Europe

Bilateral knee examination with Lachmeter®

Centre Hospitalier Universitaire de Nice

Ligament; Laxity

06/24

02/25

TAGS, NCT06314191: Adipose Tissue and Symptomatic Gonarthrosis

Not yet recruiting

N/A

Europe

blood sampling, knee radiography

Centre Hospitalier Universitaire de Nice

Gonarthrosis, Obesity

06/25

11/25

Calprotectine, NCT05555433: in Spondyloarthritis

Recruiting

N/A

190

Europe

NO INTERVENTION

Centre Hospitalier Universitaire de Nice

Spondylarthritis

08/24

InCHO, NCT06347328: The Benefits of Posterior Joint Infiltration in Chronic Low Back Pain

Not yet recruiting

N/A

102

Europe

echo-guided infiltration, non-echo-guided infiltration

Centre Hospitalier Universitaire de Nice

Chronic Low-back Pain

01/27

03/27

MAJIK, NCT04602091: Observational Study in Patients Treated With JAK Inhibitors for Inflammatory Rheumatism

Recruiting

N/A

2300

Europe

no intervention

Societe Francaise de Rhumatologie, Bordeaux PharmacoEpi

Rheumatoid Arthritis, Inflammatory Rheumatism, Psoriatic Arthritis, Spondyloarthritis

06/26

06/30

INCREDIBLE, NCT06643845: Can Multimodal Medical Strategies Can Delay Total Knee Replacement?

Not yet recruiting

N/A

1000

Europe

arthroplasty, Medical and non-medical treatments

University Hospital, Brest

Osteoarthritis, Knee

07/30

EPROGE, NCT06466330: Efficacy of Microparticle Geniculate Artery Embolization in Total Knee Prosthesis Patients With Pain Resistant to Medical Treatment. A Prospective Randomized Controlled Trial

Recruiting

N/A

112

Europe

microparticles, embolization, sham embolization

Societe Francaise de Rhumatologie, Centre Hospitalier Universitaire de Nice, Euraxi Pharma

Knee Pain Chronic, Knee Pain Swelling

02/26

02/27

SMAP, NCT06059430: Cohort Project of Patients With Inflammatory Rheumatism

Not yet recruiting

N/A

1000

Europe

no intervention

Centre Hospitalier Universitaire de Nice

Rheumatoid Arthritis, Spondyloarthritis, Axial, Psoriatic Arthritis

09/43

12/43

NCT05593640: Thromboxane A2 and Osteoarthritis

Recruiting

N/A

Europe

biological samples

Centre Hospitalier Universitaire de Nice, French Society of Rheumatology

Osteoarthritis

09/23

REG-HYPO, NCT05596539: Prospective, Longitudinal, Observational Registry of Adult Patients with Hypophosphatasia

Recruiting

N/A

100

Europe

Data collection

Assistance Publique - Hôpitaux de Paris

Hypophosphatasia

03/25

03/31

NCT05592574: IL17 Rate and Spondyloarthritis

Recruiting

N/A

Europe

Blood sample

Centre Hospitalier Universitaire de Nice

Spondylarthritis

01/41

Zemouri, Sofia

FLUO, NCT05409612 / 2021-002691-39: Trial Assessing the Immunogenicity and Safety of Two Influenza Vaccine Strategies Among Severe Obese Adult Patients

Completed

206

Europe

Supemtek®, Vaxigriptetra®

Assistance Publique - Hôpitaux de Paris, Sanofi Pasteur, a Sanofi Company, Hospices Civils de Lyon

Morbid Obesity, Severe Obesity

04/23

10/23

OPPORTOS, NCT03570177: Fracture Prediction by Opportunistic Screening for Osteoporosis

Active, not recruiting

N/A

173720

Europe

Assistance Publique - Hôpitaux de Paris

Fractures Related to Skeleton Fragility

10/24

01/25

DAICAP, NCT05513820: Automatic Detection in MRI of Prostate Cancer:

Recruiting

N/A

1250

Europe

Detection and Characterization of Prostate Cancer Based on Artificial Intelligence

12/24

TOOLBAR, NCT04941651: Efficacy of Telenutrition for the Treatment of Overweight Patients With Obesity and/or High Cardiometabolic Risk

Recruiting

N/A

346

Europe

OBE-COACH program, Connected devices, Connected Activity Tracer, e-learning program

Assistance Publique - Hôpitaux de Paris

Overweight and Obesity

11/25

11/26

Mathon, Bertrand

Recruiting

Europe

Laser technology for intracerebral thermocoagulation

Assistance Publique - Hôpitaux de Paris, Medtronic

Drug-resistant Focal Epilepsy, Epilepsy, Epilepsies, Focal, Focal Epilepsy, Drug Resistant

09/23

08/24

SAPPHYRE, NCT04746625: Safety and Performance of the PolarisÂ® 24 Adjustable Valve System in Hydrocephalus Patients' Treatment

Recruiting

N/A

126

Europe

Sophysa

Hydrocephalus

06/24

06/28

OPSTIMVAG, NCT04693221: Optimization of the Parameters of Vagal Nerve Stimulation

Recruiting

N/A

140

Europe

Choice of VNS set of parameters based on the lowest PLI, EEG

Assistance Publique Hopitaux De Marseille

Epilepsy

06/25

12/26

MicroECoGG, NCT06408428: Glioma Intraoperative MicroElectroCorticoGraphy

Not yet recruiting

N/A

Europe

PANAXIUM MicroECoG

Institut National de la Santé Et de la Recherche Médicale, France, PANAXIUM

Glioma, Epilepsy

09/27

03/28

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