| Dummer, Reinhard |
DAR-UM-2, NCT05987332: IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma |
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| Recruiting | 2/3 | 420 | Europe, Canada, US, RoW | IDE196, Darovasertib, Crizotinib, XALKORI, Pembrolizumab, Keytruda, Ipilimumab, Yervoy, Nivolumab, Opdivo, Dacarbazine, DTIC-Dome | IDEAYA Biosciences | Metastatic Uveal Melanoma | 01/27 | 01/28 | | |
Nov IIT- Pyrex, NCT04652258: Pyrexia Management Using an IL-6 Antibody in BRAF+ Melanoma Patients Treated with Dabrafenib/ Trametinib +/- Immunotherapy |
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| Terminated | 2 | 20 | Europe | Actemra | University of Zurich | Pyrexia | 10/21 | 10/21 | | |
NCT05529316: A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma |
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| Active, not recruiting | 2 | 220 | Europe, US, RoW | Botensilimab, AGEN1181, Balstilimab, AGEN2034 | Agenus Inc. | Advanced Melanoma | 05/28 | 05/28 | | |
| Recruiting | 2 | 40 | Europe | L19IL2 +L19TNF, bifikafusp alfa + onfekafusp alfa | Philogen S.p.A., Philogen S.p.A. | Carcinoma, Basal Cell, Carcinoma, Cutaneous Squamous Cell | 09/24 | 09/24 | | |
NCT04679480: Anti-PD1-antibody and Pulsed HHI for Advanced BCC |
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| Active, not recruiting | 2 | 20 | Europe | Cemiplimab Injection [Libtayo], Sonidegib | Reinhard Dummer, Sanofi, Sun Pharmaceutical Industries Ltd | Basal Cell Carcinoma | 12/24 | 12/24 | | |
| Recruiting | 1/2 | 100 | Europe | Pembrolizumab+T3P-Y058-739, T3P-Y058-739 (IV), T3P-Y058-739 (IT) | T3 Pharmaceuticals AG | Advanced Solid Tumor | 02/26 | 10/26 | | |
| Active, not recruiting | 1/2 | 274 | Europe | visugromab (CTL-002) | CatalYm GmbH, CatalYm GmbH | Solid Tumor, Adult | 10/25 | 10/27 | | |
| Recruiting | 1 | 275 | Europe, Canada, US | PF-08046049 | Seagen Inc. | Cutaneous Melanoma, Non-small Cell Lung Cancer, Colorectal Neoplasms, Pancreatic Neoplasms, Mesothelioma | 11/26 | 11/27 | | |
| Kriemler, Susi |
CiaoCorona, NCT04448717: COVID-19: Longitudinal Study of Seroprevalence of SARS-CoV-2 Antibodies and Development of Immunity in School Children |
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| Recruiting | N/A | 8000 | Europe | COVID-19 Antibody testing | University of Zurich, Swiss School of Public Health (SSPH+) | SARS-CoV 2, COVID-19 | 12/23 | 12/23 | | |
| Bloch, Konrad E |
NCT03537924: Effect of Acetazolamide on Right Heart Function During Exercise in Lowlanders Older Than 40 Years at Altitude |
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| Active, not recruiting | 4 | 100 | RoW | ACETAZOLAMIDE oral capsule, Placebo oral capsule | University of Zurich, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov | Altitude Hypoxia | 12/22 | 12/22 | | |
NCT03539367: Effect of Acetazolamide on Lung Water Content by Ultrasound in Lowlanders Older Than 40 Years at Altitude |
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| Active, not recruiting | 4 | 100 | RoW | ACETAZOLAMIDE oral capsule, Placebo oral capsule | University of Zurich, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov | Altitude Hypoxia | 12/22 | 12/22 | | |
NCT06498531: HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men |
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| Recruiting | 4 | 270 | RoW | Acetazolamide, Placebo | University of Zurich, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov, University Hospital Heidelberg, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques | Sleep-Disordered Breathing | 12/25 | 12/25 | | |
NCT06499727: HighCycle Study: Effect of Acetazolamide on Acute Mountain Sickness in Women Compared to Men |
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| Recruiting | 4 | 270 | RoW | Acetazolamide, Placebo | University of Zurich, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov, University Hospital Heidelberg, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques | Acute Mountain Sickness | 12/25 | 12/25 | | |
NCT06498505: HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to Men |
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| Recruiting | 4 | 270 | RoW | Acetazolamide, Placebo | University of Zurich, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov, University Hospital Heidelberg, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques | High Altitude | 12/25 | 12/25 | | |
NCT03540914: Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders Older Than 40 Years at Altitude. |
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| Active, not recruiting | 4 | 400 | RoW | ACETAZOLAMIDE oral capsule, Placebo oral capsule | University of Zurich, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov | Altitude Hypoxia | 12/24 | 12/24 | | |
NCT04913389: Acetazolamide to Prevent Impending Altitude-illness in Patients With COPD |
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| Active, not recruiting | 3 | 100 | RoW | Acetazolamide, Acetazolamide, oral capsule, Placebo, Placebo, oral capsule | University of Zurich, National Center of Cardiology and Internal Medicine, Kyrgyz Republic | Chronic Obstructive Pulmonary Disease, Altitude Sickness, Altitude Hypoxia | 08/22 | 12/23 | | |
NCT06499714: HighCycle Study: Effect of High Altitude on Acute Mountain Sickness in Women Related to Their Menstrual Cycle Phase |
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| Recruiting | N/A | 90 | RoW | Exposure to 3600 m | University of Zurich, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov, University Hospital Heidelberg, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques | Acute Mountain Sickness | 12/25 | 12/25 | | |
NCT06498544: HighCycle Study: Effect of High Altitude on Sleep Disordered Breathing in Women Related to Their Menstrual Cycle Phase |
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| Recruiting | N/A | 90 | RoW | Exposure to 3600 m | University of Zurich, National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov, University Hospital Heidelberg, Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques | Sleep-Disordered Breathing | 12/25 | 12/25 | | |
| Erne, Paul |
| Recruiting | N/A | 1000 | Europe | No intervention | Hypertension Excellence Centre Lucerne | Cardiovascular Risk Factors | 09/24 | 09/34 | | |
| Ehlert, Ulrike |
NCT04183946: Willkommen Mutterglück: Online CBT for Pregnant and Postpartum Women With Depression and Anxiety |
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| Not yet recruiting | N/A | 300 | Europe | Online Cognitive Behavioural Therapy, Willkommen Mutterglück: Online CBT program for pre-postnatal depression & anxiety | University of Zurich, Ambulatorium für kognitive Verhaltenstherapie und Verhaltensmedizin - UZH, Lamprecht AG | Prenatal Anxiety, Generalized Anxiety, Postpartum Depression, Major Depressive Disorder | 01/22 | 01/24 | | |
| Weller, Michael |
USZ-STRIKE, NCT05522660: Immunotherapy or Targeted Therapy with or Without Stereotactic Radiosurgery for Patients with Brain Metastases from Melanoma or Non-small Cell Lung Cancer |
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| Recruiting | 3 | 190 | Europe | Stereotactic radiosurgery, Immune checkpoint inhibitor, standard of care treatment | ETOP IBCSG Partners Foundation, USZ Foundation | Non-Small Cell Lung Cancer, Melanoma | 01/26 | 12/26 | | |
GUIDANCE, NCT05050084: Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score |
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| Recruiting | 3 | 2050 | Canada, US | Bicalutamide, Casodex, Cosudex, ICI 176,334, ICI 176334, Buserelin, 6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing Hormone-releasing Factor (Pig), BSRL, Busereline, Etilamide, HOE 766, ICI 123215, S74-6766, Darolutamide, Antiandrogen ODM-201, BAY 1841788, BAY-1841788, BAY1841788, Nubeqa, ODM 201, ODM-201, Degarelix, FE200486, Firmagon, Flutamide, 4'-Nitro-3'-trifluoromethylisobutyranilide, Apimid, Cebatrol, Chimax, Cytomid, Drogenil, Euflex, Eulexine, Flucinom, Flucinome, Flugerel, Fluken, Flulem, FLUT, Fluta-Gry, Flutabene, Flutacan, Flutamex, Flutamin, Flutan, Flutaplex, Fugerel, Grisetin, Niftolide, Oncosal, Profamid, Propanamide, 2-Methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-, Prostacur, Prostadirex, Prostica, Prostogenat, Sch 13521, Tafenil, Tecnoflut, Testotard, Goserelin, ICI-118630, Histrelin, Leuprolide, Leuprorelin, Radiation Therapy, Cancer Radiotherapy, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation, Relugolix, N-(4-(1-((2,6-Difluorophenyl)methyl)-5-((dimethylamino)methyl)-1,2,3,4-tetrahydro-3-(6-methoxy-3-pyridazinyl)-2,4-dioxothieno(2,3-d)pyrimidin-6-yl)phenyl)-N'-methoxyurea, Orgovyx, TAK 385, TAK-385, Triptorelin, 6-D-Tryptophan-LH-RH, 6-D-Tryptophanluteinizing Hormone-releasing Factor, AY-25650, CL-118,532, Detryptoreline | NRG Oncology, National Cancer Institute (NCI) | Prostate Adenocarcinoma | 04/32 | 04/37 | | |
| Recruiting | 2/3 | 1030 | Europe, Canada, US, RoW | Temozolomide, Temodar, Temodal, Temcad, Lomustine, CCNU, CeeNU, Gleostine, Regorafenib, Stivarga, BAY 73-4506, Radiation, Paxalisib, GDC-0084, VAL-083, Dianhydrogalactitol, VT1021, Troriluzole, BHV-4157, ADI-PEG 20, Pegargiminase | Global Coalition for Adaptive Research, Bayer, Kazia Therapeutics Limited, Kintara Therapeutics, Inc., Biohaven Pharmaceuticals, Inc., Vigeo Therapeutics, Inc., Polaris Group | Glioblastoma | 06/26 | 06/28 | | |
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| Active, not recruiting | 2 | 210 | Europe, US | Berubicin, Berubicin Hydrochloride, Lomustine, Lomustine Capsules, CCNU, CeeNU, Gleostine | CNS Pharmaceuticals, Inc., Worldwide Clinical Trials | Glioblastoma Multiforme, Adult | 12/24 | 03/25 | | |
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| Active, not recruiting | 2 | 20 | Europe, RoW | Sonidegib, Cisplatin, Lomustine, Vincristine, radiotherapy | European Organisation for Research and Treatment of Cancer - EORTC, EORTC-BTG, Sunpharmaceuticals | Medulloblastoma | 04/25 | 04/25 | | |
iNPH, NCT02495610: Novel Parameters for the Prediction of Ventriculoperitoneal Shunting Efficacy in Patients With |
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| Active, not recruiting | N/A | 70 | Europe | Gait analysis and MRI: | University of Zurich | Idiopathic Normal Pressure Hydrocephalus | 10/24 | 12/24 | | |
ETERNITY, NCT03770468: Molecular Genetic, Host-derived and Clinical Determinants of Long-term Survival in Glioblastoma |
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| Completed | N/A | 599 | Europe, US | Blood drawl | European Organisation for Research and Treatment of Cancer - EORTC | Glioblastoma | 08/23 | 08/23 | | |
NCT05259605: Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification |
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| Recruiting | N/A | 1250 | Europe | Observational | European Organisation for Research and Treatment of Cancer - EORTC | Glioma, Glioneuronal Tumor, Choroid Plexus Tumor, Pineal Tumors, Germ Cell Tumor, Tumor of the Sellar Region, Diffuse Midline Glioma, H3 K27M-Mutant, Ependymoma, Embryonal Tumor, Pineal Tumor, Hemangiopericytoma, Hemangioblastoma, Melanocytic Tumor of CNS | 08/26 | 12/26 | | |
| Günthard, Huldrych |
NCT00537966: Characterization of Acute and Recent HIV-1 Infections in Zurich. |
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| Recruiting | N/A | 800 | Europe | Dolutegravir, Tivicay, Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamid Fumarate, Genvoya, Raltegravir, isentress, Darunavir, Prezista, Ritonavir, Norvir, Rilpivirine, Edurant, Lamivudine, 3TC, tenofovir, Viread, Emtricitabine, Emtriva, Abacavir, Ziagen | University of Zurich | HIV Infections | 12/28 | 12/28 | | |
| Recruiting | N/A | 37853 | Europe, RoW | | Rigshospitalet, Denmark, Gilead Sciences, ViiV Healthcare | HIV | 12/25 | 12/25 | | |
| Puhan, Milo A |
| Recruiting | N/A | 10000 | Europe | | Swiss Multiple Sclerosis Registry, University of Zurich, Epidemiology, Biostatistics and Prevention Institute, Schweizerische Multiple Sklerose Gesellschaft | Multiple Sclerosis | 06/41 | 06/41 | | |
| Curt, Armin |
| Completed | 2 | 129 | Europe, RoW | NG-101, Placebos | University of Zurich, EMSCI.org, State Secretariat for Education Research and Innovation, Switzerland, Horizon 2020 - European Commission, Foundation Wings For Life, Swiss Paraplegic Research, Heidelberg University Hospital Spinal Cord Injury Center, KKS Netzwerk | Spinal Cord Injury, Acute | 02/23 | 02/23 | | |
NCT04555759: Validity and Reliability of the 2-minute Walk Test in Individuals With a Spinal Cord Injury |
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| Completed | N/A | 50 | Europe | 2-minute walk test | University of Zurich, Swiss Paraplegic Research | Spinal Cord Injuries | 06/21 | 06/21 | | |
| Completed | N/A | 55 | Europe | | University of Zurich | Spinal Cord Injuries | 07/21 | 07/21 | | |
NCT06443281: Pain Phenotyping in Patients with Neuropathic Pain After Spinal Cord Injury |
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| Recruiting | N/A | 300 | Europe | Neurophysiology, Cardiovascular test, Experimental pain paradigms, Quantitative sensory testing, Clinical pain phenotype | University of Zurich, Swiss National Science Foundation | Spinal Cord Injuries, Pain, Neuropathic, Nociceptive Pain, Neuropathy | 04/30 | 04/30 | | |
| Recruiting | N/A | 114 | Europe | VERUM TTNS, SHAM TTNS | University of Zurich, Swiss National Science Foundation, Clinique Romande de Readaptation, Rehab Basel, Swiss Paraplegic Research, Nottwil, BioMedical Research Forschungslabor für Urologie, University of Bern, Translational Neuro-Urology Department of Biomedicine, University of Porto, Center for Lower Urinary Tract Research School of Medicine, University of Pittsburgh | Spinal Cord Injury, Acute | 09/26 | 09/26 | | |
DBS-SCI, NCT03053791: Deep Brain Stimulation in Patients With Incomplete Spinal Cord Injury for Improvement of Gait |
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| Recruiting | N/A | 5 | Europe | Deep brain stimulation in mesencephalic locomotor region, Implantation of a Deep brain stimulation system | University of Zurich, Balgrist University Hospital, ETH Zurich, Wings for Life | Spinal Cord Injury | 12/26 | 12/27 | | |
NCT02165787: Investigation of Gait Parameters in Health and Neurological Disease Under Varying Locomotor Conditions |
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| Recruiting | N/A | 340 | Europe | | University of Zurich | Gait Analysis in Neurological Disorders | 03/25 | 03/25 | | |
| Recruiting | N/A | 450 | Europe | MRI | University of Zurich | Spinal Cord Injuries | 06/27 | 06/27 | | |
| Recruiting | N/A | 35 | Europe | MRI | University of Zurich | Stroke | 06/27 | 06/27 | | |
| Recruiting | N/A | 70 | Europe | MRI | University of Zurich, ETH Zurich | Amputation, Congenital, Upper Limb; Amelia | 06/27 | 06/27 | | |
NCT02936453: STIMO: Epidural Electrical Simulation (EES) With Robot-assisted Rehabilitation in Patients With Spinal Cord Injury. |
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| Active, not recruiting | N/A | 10 | Europe | Device implantation | Jocelyne Bloch, Ecole Polytechnique Fédérale de Lausanne, Foundation Wings For Life | Spinal Cord Injury | 07/26 | 07/26 | | |
NCT01571531: European Multicentre Study of Human Spinal Cord Injury |
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| Recruiting | N/A | 8000 | Europe | | University of Zurich | Spinal Cord Injury | 08/26 | 08/26 | | |
NCT02170155: MRI-changes in Morphometry and Cerebro Spinale Fluid (CSF) Flow in Spinal Cord Disorders |
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| Recruiting | N/A | 350 | Europe | | University of Zurich, Foundation Wings For Life, Balgrist Foundation | Spinal Injury | 12/26 | 12/26 | | |
| Luft, Andreas |
| Active, not recruiting | 3 | 610 | Europe | IMP Levodopa 100mg/Carbidopa 25mg, Matching placebo | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Acute Stroke, Stroke Rehabilitation | 08/24 | 06/29 | | |
CHEST, NCT04573114: Cerebral Hemodynamics During Early Verticalization After (Successful) Thrombectomy Poststroke |
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| Recruiting | N/A | 80 | Europe | Verticalization | University of Zurich | Stroke, Healthy | 12/22 | 12/22 | | |
NCT05820074: Investigating Neural Biomarkers for Gait in Parkinson's Patients |
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| Recruiting | N/A | 60 | Europe | Neural Activity Recording, Electroencephalography (EEG), Local-Field-Potentials with deep brain stimulation electrodes, Movement Parameter Recording, Motion capture, Accelerometers, Electromyography, Neuromodulation | Swiss Federal Institute of Technology, cereneo center for Neurology and Rehabilitation, University of Zurich | Parkinson Disease, Gait Disorders, Neurologic | 03/25 | 03/25 | | |
| Jetter, Alexander |
NCT04384562: Studying the Role of Brain Molecules for Decision Making |
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| Completed | N/A | 160 | Europe | Methylphenidate, Ritalin®, Reboxetine, Edronax®, Nicotine gum, Nicorette®, Placebo pill, Placebo gum | University of Zurich | Decision Making, Healthy | 12/21 | 12/21 | | |
| Radtke, Thomas |
NCT05505617: Nitric Oxide Lung Diffusing Capacity in Systemic Sclerosis |
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| Recruiting | N/A | 23 | Europe | Single-breath nitric oxide lung diffusing capacity measurements according to type of device in random order. | Holger Dressel, University of Zurich | Systemic Sclerosis | 01/25 | 06/25 | | |
| Schubert, Martin |
NCT01571531: European Multicentre Study of Human Spinal Cord Injury |
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| Recruiting | N/A | 8000 | Europe | | University of Zurich | Spinal Cord Injury | 08/26 | 08/26 | | |
| Frei, Anja |
NCT05696730: Holistic Wellbeing in COPD: Communication About Sexuality (COSY) |
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| Completed | N/A | 36 | Europe | Communication intervention about sexuality in people with COPD | University of Zurich | Chronic Disease, Lung Diseases, Obstructive, Respiratory Disease | 03/24 | 03/24 | | |
| Recruiting | N/A | 88 | Europe | Lifestyle | Kai-Uwe Schmitt, PhD, MEng, ICID | Non-Small Cell Lung Cancer (NSCLC) | 12/25 | 01/26 | | |
| Wiest, Roland |
NCT04020744: Real-time fMRI Neurofeedback in Patients With MCI |
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| Completed | N/A | 84 | Europe | real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area | University of Bern, University of Zurich | Mild Cognitive Impairment | 10/23 | 01/24 | | |
| Tobler, Philippe N |
NCT04384562: Studying the Role of Brain Molecules for Decision Making |
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| Completed | N/A | 160 | Europe | Methylphenidate, Ritalin®, Reboxetine, Edronax®, Nicotine gum, Nicorette®, Placebo pill, Placebo gum | University of Zurich | Decision Making, Healthy | 12/21 | 12/21 | | |
| Dressel, Holger |
NCT05505617: Nitric Oxide Lung Diffusing Capacity in Systemic Sclerosis |
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| Recruiting | N/A | 23 | Europe | Single-breath nitric oxide lung diffusing capacity measurements according to type of device in random order. | Holger Dressel, University of Zurich | Systemic Sclerosis | 01/25 | 06/25 | | |
| Maggi, Marion |
NCT05505617: Nitric Oxide Lung Diffusing Capacity in Systemic Sclerosis |
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| Recruiting | N/A | 23 | Europe | Single-breath nitric oxide lung diffusing capacity measurements according to type of device in random order. | Holger Dressel, University of Zurich | Systemic Sclerosis | 01/25 | 06/25 | | |
| Michels, Lars |
| Completed | N/A | 70 | Europe | real-time fMRI | University of Zurich, Swiss National Science Foundation | Healthy | 12/21 | 12/22 | | |
| Active, not recruiting | N/A | 70 | Europe | neurofeedback | University of Zurich, USZ Foundation | Visual Snow Syndrome, Neuro-Ophthalmology | 08/23 | 12/23 | | |
NCT04020744: Real-time fMRI Neurofeedback in Patients With MCI |
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| Completed | N/A | 84 | Europe | real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area | University of Bern, University of Zurich | Mild Cognitive Impairment | 10/23 | 01/24 | | |
NCT05524493: High-field MR Imaging in Migraine, Visual Snow and Epilepsy |
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| Not yet recruiting | N/A | 200 | Europe | Structural MRI, Quantitative MRI, Diffusion MRI, fMRI, MR Spectroscopy | University of Zurich, Balgrist University Hospital | Migraine, Epilepsy, Visual Snow Syndrome | 06/26 | 06/26 | | |
| Scharnowski, Frank |
NCT04020744: Real-time fMRI Neurofeedback in Patients With MCI |
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| Completed | N/A | 84 | Europe | real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area | University of Bern, University of Zurich | Mild Cognitive Impairment | 10/23 | 01/24 | | |
| Watzke, Birgit |
| Completed | N/A | 201 | Europe | Telephone-administered continuation therapy, Usual care, Treatment as usual (TAU) | University of Zurich, Universitätsklinikum Hamburg-Eppendorf, University Hospital, Zürich | Depressive Disorder | 04/23 | 04/23 | | |
CoLiPri, NCT04233853: Consultation-Liaison Intervention for Patients With Depression and Anxiety in Primary Care |
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| Active, not recruiting | N/A | 82 | Europe | CoLiPri intervention, Consultation-liaison service, Usual primary care enhanced | University of Zurich, Heidelberg University | Depression, Anxiety | 03/24 | 03/24 | | |
ISA-Bell, NCT05553197: Intersession Processes in Psychotherapeutic Treatments Using an Ecological Momentary Assessment Approach |
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| Recruiting | N/A | 84 | Europe | Cognitive Behavioural Therapy (CBT), Ecological Momentary Assessment (EMA) | Birgit Watzke, Universität Tübingen | Depression | 12/24 | 12/24 | | |
| Schneider, Sophie |
ELDERLY, NCT03977194: Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Carboplatin Paclitaxel Chemotherapy |
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| Active, not recruiting | 3 | 500 | Europe | Carboplatin, Paclitaxel, Atezolizumab | Intergroupe Francophone de Cancerologie Thoracique | Non Small Cell Lung Cancer Metastatic | 12/24 | 12/26 | | |
ORBITAL, NCT04233021: Study of Osimertinib in Patients with a Lung Cancer with Brain or Leptomeningeal Metastases with EGFR Mutation |
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| Completed | 2 | 57 | Europe | Osimertinib | Intergroupe Francophone de Cancerologie Thoracique | Non Small Cell Lung Cancer Metastatic, Leptomeningeal Metastasis, Brain Metastases, EGFR Activating Mutation | 03/23 | 12/24 | | |
ORAKLE, NCT04111705: Lorlatinib After Failure of First-line Second-generation ALK Kinase Inhibitor in Patients with Advanced ALK-positive Non-small Cell Lung Cancer |
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| Active, not recruiting | 2 | 23 | Europe | Lorlatinib | Intergroupe Francophone de Cancerologie Thoracique | Non Small Cell Lung Cancer Metastatic | 01/25 | 01/25 | | |
| Not yet recruiting | 2 | 115 | Europe | Atezolizumab 1200 mg IV, Tiragolumab 600 mg IV | Gustave Roussy, Cancer Campus, Grand Paris, Roche Global Development | Metastatic Cancer Lung, Advanced Lung Cancer, CBNPC Cancer | 01/28 | 01/30 | | |
ICARS, NCT06219317: Immunotherapy Consolidation After Radical Treatment of Synchronous Oligo-metastatic NSCLC |
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| Recruiting | 2 | 136 | Europe | Cemiplimab, Placebo | European Organisation for Research and Treatment of Cancer - EORTC | NSCLC Stage IV | 01/30 | 01/30 | | |
NCT04621188: Lorlatinib After Failure of First-line TKI in Patients with Advanced ROS1-positive NSCLC (ALBATROS) |
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| Recruiting | 2 | 84 | Europe | Lorlatinib | Intergroupe Francophone de Cancerologie Thoracique | Non Small Cell Lung Cancer Metastatic | 03/25 | 01/26 | | |
ADAPTABLE, NCT05781308: Combination of Paclitaxel-bevacizumab ± Atezolizumab in Patients with Advanced NSCLC Progressing After Immunotherapy & Chemotherapy |
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| Active, not recruiting | 2 | 156 | Europe | Paclitaxel, Bevacizumab, Avastin, Atezolizumab, Tecentriq | Intergroupe Francophone de Cancerologie Thoracique | Non Small Cell Lung Cancer | 09/25 | 06/26 | | |
NCT01817192: Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer |
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| Recruiting | N/A | 1050 | Europe, US | Adjuvant Chemotherapy, Radiographic surveillance, 14-Gene Prognostic Assay | Razor Genomics, Encore Clinical | Non-Small Cell Lung Cancer | 05/27 | 05/27 | | |
ROSIE, NCT06053099: A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19) |
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| Recruiting | N/A | 300 | Europe | Plasma ctDNA, FFPE blocks | Intergroupe Francophone de Cancerologie Thoracique | Non Small Cell Lung Cancer, EGFR Activating Mutation, EGFR DEL19, EGFR L858R | 10/31 | 10/31 | | |
| Klöppel, Stefan |
NCT04277104: Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance? |
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| Completed | N/A | 47 | Europe | Closed loop acoustic stimulation, Sham acoustic stimulation | University of Bern | Healthy, Mild Cognitive Impairment, Alzheimer Disease | 07/23 | 07/23 | | |
NCT04882527: Modulating Prospective Memory in Older Adults With Non-invasive Brain Stimulation |
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| Completed | N/A | 106 | Europe | Non-invasive brain stimulation, high-definition transcranial direct current stimulation, HD-tDCS, Soterix medical, Sham stimulation | University of Bern | Healthy Aging | 10/23 | 10/23 | | |
NCT04020744: Real-time fMRI Neurofeedback in Patients With MCI |
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| Completed | N/A | 84 | Europe | real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area | University of Bern, University of Zurich | Mild Cognitive Impairment | 10/23 | 01/24 | | |
| Completed | N/A | 162 | Europe | Computerized Cognitive Training, Documentaries with delayed Computerized Cognitive Training | University of Bern | Alzheimer Disease, Dementia, Mild Cognitive Impairment | 07/24 | 10/24 | | |
| Klink, Katharina |
NCT04020744: Real-time fMRI Neurofeedback in Patients With MCI |
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| Completed | N/A | 84 | Europe | real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area | University of Bern, University of Zurich | Mild Cognitive Impairment | 10/23 | 01/24 | | |
| Held, Jeremia |
CHEST, NCT04573114: Cerebral Hemodynamics During Early Verticalization After (Successful) Thrombectomy Poststroke |
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| Recruiting | N/A | 80 | Europe | Verticalization | University of Zurich | Stroke, Healthy | 12/22 | 12/22 | | |
NCT05524727: PEMOCS: Personalized Motor-cognitive Training in Chronic Stroke |
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| Active, not recruiting | N/A | 38 | Europe | Concept-guided, personalized, motor-cognitive training by means of an exergame | University of Zurich | Stroke | 07/24 | 07/24 | | |
| Peter, Jessica |
NCT03959462: Supporting Decisions With Transcranial Direct Current Stimulation in Healthy Young and Elderly Individuals |
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| Completed | N/A | 254 | Europe | real anodal transcranial direct current stimulation, sham transcranial direct current stimulation | University of Bern, Novartis | Real tDCS, Sham tDCS | 08/22 | 12/22 | | |
NCT04882527: Modulating Prospective Memory in Older Adults With Non-invasive Brain Stimulation |
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| Completed | N/A | 106 | Europe | Non-invasive brain stimulation, high-definition transcranial direct current stimulation, HD-tDCS, Soterix medical, Sham stimulation | University of Bern | Healthy Aging | 10/23 | 10/23 | | |
NCT04020744: Real-time fMRI Neurofeedback in Patients With MCI |
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| Completed | N/A | 84 | Europe | real-time fMRI based neurofeedback from the hippocampus, real-time fMRI based neurofeedback from another brain area | University of Bern, University of Zurich | Mild Cognitive Impairment | 10/23 | 01/24 | | |
| Zbinden, Reinhard |
| Recruiting | N/A | 17500 | Europe | compare data patterns by data-driven algorithms to determine sepsis, compare data patterns by data-driven algorithms to predict sepsis-related mortality | University Hospital, Basel, Switzerland, Swiss Personalized Health Network (SPHN), Personalized Health and Related Technologies (PHRT) initiative of ETH Zürich | Sepsis | 06/22 | 06/23 | | |
| Terminated | N/A | 3 | Europe | compare data patterns by data-driven algorithms to determine sepsis, compare data patterns by data-driven algorithms to predict sepsis-related mortality | University Hospital, Basel, Switzerland, Swiss Personalized Health Network (SPHN), Personalized Health and Related Technologies (PHRT) initiative of ETH Zürich | Sepsis, Severe Community-acquired Pneumonia (sCAP), Infection, Bacterial | 07/22 | 07/22 | | |
NCT04172025: Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens |
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| Recruiting | N/A | 10000 | Europe | Analysis of Bacterial Genome | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Multiresistant Bacterial Pathogens, Virulent Bacterial Pathogens | 12/29 | 12/29 | | |
| Perreten, Vincent |
NCT04172025: Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens |
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| Recruiting | N/A | 10000 | Europe | Analysis of Bacterial Genome | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Multiresistant Bacterial Pathogens, Virulent Bacterial Pathogens | 12/29 | 12/29 | | |
| Stephan, Roger |
NCT04172025: Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens |
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| Recruiting | N/A | 10000 | Europe | Analysis of Bacterial Genome | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Multiresistant Bacterial Pathogens, Virulent Bacterial Pathogens | 12/29 | 12/29 | | |
| Sidorenko, Nikita |
NCT04384562: Studying the Role of Brain Molecules for Decision Making |
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| Completed | N/A | 160 | Europe | Methylphenidate, Ritalin®, Reboxetine, Edronax®, Nicotine gum, Nicorette®, Placebo pill, Placebo gum | University of Zurich | Decision Making, Healthy | 12/21 | 12/21 | | |
| Heim, Eva |
NCT05917613: Complex-Posttraumatic Stress Disorder - Cultural Adaptation of a Therapeutic Manual and Development of a Culture-specific Diagnostic Module for Refugee Populations in Switzerland (Pilot Trial) |
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| Active, not recruiting | N/A | 24 | Europe | Enhanced Skills Training in Affective and Interpersonal Regulation combined with Modified Prolonged Exposure (ESTAIR/MPE) | Eva Heim | Complex Post-Traumatic Stress Disorder | 06/25 | 06/25 | | |
| Huber, Michael |
NCT04172025: Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens |
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| Recruiting | N/A | 10000 | Europe | Analysis of Bacterial Genome | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Multiresistant Bacterial Pathogens, Virulent Bacterial Pathogens | 12/29 | 12/29 | | |
| Boris, Quednow |
NCT04384562: Studying the Role of Brain Molecules for Decision Making |
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| Completed | N/A | 160 | Europe | Methylphenidate, Ritalin®, Reboxetine, Edronax®, Nicotine gum, Nicorette®, Placebo pill, Placebo gum | University of Zurich | Decision Making, Healthy | 12/21 | 12/21 | | |
| Lenggenhager, Bigna |
| Completed | N/A | 29 | Europe | Embodied virtual reality | University of Zurich, Balgrist University Hospital | Complex Regional Pain Syndromes, Complex Regional Pain Syndrome Type I of the Upper Limb, Complex Regional Pain Syndrome I (CRPS I), Complex Regional Pain Syndrome I of Upper Limb, Complex Regional Pain Syndrome Type II, Complex Regional Pain Syndrome II of Upper Limb, Peripheral Nerve Injury Upper Limb, Osteoarthritis Hand, Osteoarthritis Finger | 08/24 | 08/24 | | |
