Universitätsklinikum Gießen und Marburg
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 9 Trials 
18 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Neubauer, Andreas
DaunoDouble, NCT02140242 / 2013-003191-12: Comparison Between Two Dose Levels of Daunorubicin and Between One vs. Two Induction Cycles for Adult Patients With AML

Completed
3
721
Europe, RoW
study part 1 - dose daunorubicin, induction cycles
Technische Universität Dresden, University Hospital Dresden, Masaryk University
Leukemia, Myelocytic, Acute
04/22
04/22
VINCENT, NCT05904106 / 2021-003248-26: Venetoclax Plus Azacitidine Versus Intensive Chemotherapy for Fit Patients With Newly Diagnosed NPM1 Mutated AML

Recruiting
2
146
Europe
Venetoclax plus Azacitidine, standard of care chemotherapy plus gemtuzumab ozogamicin
Technische Universität Dresden, University Hospital Heidelberg, AbbVie
Acute Myeloid Leukemia
09/28
09/28
MARS-CA, NCT04034576: Mindfulness and Relaxation Interventions in Individual Psychotherapies for Children and Adolescents

Recruiting
N/A
135
Europe
Cognitive behavior therapy of trainee therapists
Heidelberg University, Esslingen University of Applied Sciences, Leibniz Institute for Research and Information in Education
Hyperkinetic Disorder, Depressive Disorder, Anxiety Disorder
07/23
02/24
NCT03188874: Clinical AML Registry and Biomaterial Database of the Study Alliance Leukemia (SAL)

Recruiting
N/A
15000
Europe
Technische Universität Dresden
Acute Myeloid Leukemia (AML)
09/30
09/30
Sander, Michael
LIBERAL, NCT03369210: Liberal Transfusion Strategy in Elderly Patients

Recruiting
3
2470
Europe
red blood cell transfusion trigger
Johann Wolfgang Goethe University Hospital, Wuerzburg University Hospital
Transfusion-dependent Anemia, Surgery, Anemia
12/24
12/25
NCT04149314: The "Hypotension Prediction Index" in Patients Undergoing Lung Surgery

Completed
N/A
142
Europe
HPI based hemodynamic optimization algorithm
University of Giessen, Edwards Lifesciences
Hypotension, Hemodynamic Instability, Renal Failure, Myocardial Injury, Anesthesia
01/23
10/23
NCT04151264: Influence of the "Hypotension Probability Index" on Intraoperative and Postoperative Hypotension in ENT- and OM-Surgery

Active, not recruiting
N/A
50
Europe
Hypotension probability index (HPI)
University of Giessen, Edwards Lifesciences
Hypotension, ENT Disease, Acute Kidney Injury, Anesthesia
06/24
12/24
Clearsight, NCT06291714: Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension

Not yet recruiting
N/A
150
NA
GDT-based hemodynamic management based on Clearsight device
University of Giessen, Edwards Lifesciences
Intraoperative Hypotension, Acute Kidney Injury, Myocardial Injury After Non-cardiac Surgery
03/25
03/26
PeriOP-CARE HF, NCT06381427: Perioperative Interdisciplinary, Intersectoral Process Optimization in Heart Failure

Not yet recruiting
N/A
1057
Europe
Interdisciplinary decision-making for perioperative care
University of Giessen, Deutsche Luft und Raumfahrt
Heart Failure
08/26
03/27
Burchert, Andreas
ENDURE-CML-IX, NCT03117816 / 2016-001030-94: ENDURE - Efficacy and Safety of AOP2014 With CML Patients in Remission

Completed
3
214
Europe
AOP2014 / Pegylated-Proline-interferon alpha-2b, Surveillance
Philipps University Marburg Medical Center, Deutsche Krebshilfe e.V., Bonn (Germany), AOP Orphan Pharmaceuticals AG
Chronic Myeloid Leukemia in Remission
01/22
12/22
NCT02375204: Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients with Relapsed or Refractory Germ Cell Tumors

Active, not recruiting
3
420
Europe, US, RoW
paclitaxel, Taxol, ifosfamide, Ifex®, IFOS, cisplatin, CDDP, pegylated G-CSF, G-CSF, carboplatin, Paraplatin®, CBDCA, etoposide phosphate, VePesid®, Toposar®, VP16, stem cell reinfusion
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI), European Organisation for Research and Treatment of Cancer - EORTC, Movember Foundation, Institute of Cancer Research (ICR), United Kingdom, Cancer Research UK, UNICANCER, Irish Group CTI
Germ Cell Tumor, Teratoma, Choriocarcinoma, Germinoma, Mixed Germ Cell Tumor, Yolk Sac Tumor, Childhood Teratoma, Malignant Germ Cell Neoplasm, Extragonadal Seminoma, Non-seminomatous Germ Cell Tumor, Seminoma
06/31
06/31
GRAPPA, NCT05153226: GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG

Active, not recruiting
3
640
Europe
Cyclophosphamide, all brands, ATG, ATG Grafalon
DKMS gemeinnützige GmbH
Graft Vs Host Disease, Peripheral Blood Stem Cell Transplantation, AML, MDS, MDS/MPN, CMML
06/25
12/26
AlloRelapseMM, NCT05675319: Allogeneic Stem Cell Transplantation vs. Conventional Therapy as Salvage Therapy for Relapsed / Progressive Patients With Multiple Myeloma After First-line Therapy

Recruiting
3
482
Europe
Allogeneic Stem Cells, carfilzomib/lenalidomide/dexamethasone (KRD), elotuzumab/lenalidomide/dexamethasone (ERD), daratumumab/bortezomib/dexamethasone (DVD), daratumumab/lenalidomide/dexamethasone (DRD), ixazomib/lenalidomide/dexamethasone (IRD), pomalidomide/bortezomib/dexamethasone (PVD), carfilzomib/daratumumab/dexamethasone (KDD), Autologous Stem Cells, daratumumab/pomalidomide/dexamethasone (DPD), isatuximab/carfilzomib/dexamethasone (Isa-KD), selinexor/bortezomib/dexamethasone (SVD)
Universitätsklinikum Hamburg-Eppendorf, Gemeinsamer Bundesausschuss (G-BA), Staburo GmbH
Multiple Myeloma
03/28
03/33
RELAX, NCT04330820 / 2018-003025-28: Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax

Active, not recruiting
1/2
55
Europe
Venetoclax Oral Tablet, Cytarabin
Technische Universität Dresden, AbbVie
Relapsed Adult AML, Refractory AML
10/23
08/25
Knorrenschild, Jorge Riera
INTEGRATEIIb, NCT04879368 / 2020-004617-12: RegoNivo vs Standard of Care Chemotherapy in AGOC

Active, not recruiting
3
450
Europe, Japan, US, RoW
Regorafenib, Stivarga, Nivolumab, Opdivo, Docetaxel, Taxotere, Paclitaxel, Abraxane, Irinotecan, Camptosar, Trifluridine/Tipracil, Lonsurf
Australasian Gastro-Intestinal Trials Group, Bayer, Bristol-Myers Squibb, University of Sydney, Academic and Community Cancer Research United, Taiwanese Cooperative Oncology Group, Frankfurter Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest, National Cancer Center Hospital East, Syneos Health
Gastro-Oesophageal Cancer
06/25
06/26
Engenhart-Cabillic, Rita
NCT04246684: Short RT Versus RCT,Followed by Chemo.and Organ Preservation for Interm and High-risk Rectal Cancer Patients

Active, not recruiting
3
702
Europe
Oxaliplatin, 85 mg/m2, Control arm, 5FU; 2400 mg/m2, 5-FU, control arm, 5FU, 250 mg/m2, Experimental arm: 5-FU, 5FU, 2400 mg/m2, experimental arm, Oxaliplatin 50 mg/m2, Experimental arm, Folinic Acid, 400 mg/m2, Folinic Acid, Radiotherapy control, 5x5 Gy: 25 Gy, Capecitabine, 1000 mg/m2, Capecitabine, Oxaliplatin 85 mg/m2, radiotherapy experimental, 30 x 1,8 Gy: 54 Gy, Capecitabine, 825 mg/m2, Oxaliplatin, 130 mg/m2, Oxaliplatin
Prof. Dr. med. Claus Rödel
Rectal Cancer Stage III
09/23
09/28
RADIANCE, NCT04230759 / 2018-003005-25: Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. a Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group

Active, not recruiting
2
180
Europe
Chemotherapy, all brands of 5-fluorouracil (5-FU) are allowed, all brands of Mitomycin C (MMC) are allowed, Radiation, Durvalumab, PD-L1 inhibitor
Goethe University, German Cancer Aid, AstraZeneca
Anal Cancer, Anal Carcinoma, Anal Cancer Stage III, Anal Cancer Stage II
12/26
03/27
GRIPS, NCT04752280: Glioblastoma Radiotherapy Using IMRT or Proton Beams

Recruiting
N/A
326
Europe
Proton irradiation, Photon irradiation
University Hospital Heidelberg
Glioblastoma
08/25
10/27
Faoro, Charis
No trials found

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