| Evans, Linton T |
ROADS, NCT04365374: Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile- (Radiation One and Done Study) |
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| Recruiting | 3 | 180 | US | Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Carrier Tile Brachytherapy Therapy (CTBT), Stereotactic Radiation Therapy | GT Medical Technologies, Inc. | Brain Metastases | 12/25 | 12/27 | | |
ImmuneSense, NCT04485949: A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma |
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| Active, not recruiting | 2 | 93 | US | IGV-001 Cell Immunotherapy, Placebo, Standard of Care (SOC): Radiation Therapy, SOC: Temozolomide | Imvax | Glioblastoma | 01/25 | 07/27 | | |
NCT01849952: Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas |
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| Recruiting | N/A | 200 | US | | Dartmouth-Hitchcock Medical Center | Astrocytoma, Oligodendroglioma, Oligoastrocytoma, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Anaplastic Oligoastrocytoma, Glioblastoma, Brain Tumors, Brain Cancer | 05/25 | 05/25 | | |
| Recruiting | N/A | 30 | US | CONVIVO system, Conventional histologic evaluation | Dartmouth-Hitchcock Medical Center, Carl Zeiss Meditec, Inc. | Glioblastoma, Glial Tumor, Brain Metastases, Meningioma, Schwannoma, Pituitary Tumor | 06/25 | 06/25 | | |
| Recruiting | N/A | 50 | US | Pulse width modulation | Dartmouth-Hitchcock Medical Center | Spinal Fusion, Spinal Stenosis | 06/26 | 06/27 | | |
| Patel, Toral |
ROADS, NCT04365374: Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile- (Radiation One and Done Study) |
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| Recruiting | 3 | 180 | US | Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Carrier Tile Brachytherapy Therapy (CTBT), Stereotactic Radiation Therapy | GT Medical Technologies, Inc. | Brain Metastases | 12/25 | 12/27 | | |
SONOBIRD, NCT05902169: Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM |
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| Recruiting | 3 | 560 | Europe, US | SonoCloud-9 (SC9), Carboplatin, CycloButane DiCarboxylic Acid (CBDCA), Lomustine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU), Temozolomide, Temodal | CarThera | Glioblastoma, Recurrent Glioblastoma, GBM | 01/28 | 06/28 | | |
ReSPECT-GBM, NCT01906385: Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT) |
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| Recruiting | 1/2 | 55 | US | Rhenium Liposome Treatment, Rhenium-186 NanoLiposome | Plus Therapeutics, National Cancer Institute (NCI) | Glioma | 01/25 | 01/25 | | |
LIBERATE, NCT05383872: Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects with GlioBlastoma Brain Tumors |
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| Recruiting | N/A | 57 | Canada, US | Focused Ultrasound (Exablate Model 4000) | InSightec | Glioblastoma, Glioma, Liquid Biopsy | 12/24 | 03/25 | | |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
| Babu, Harish |
MTLE, NCT05135091: FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy |
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| Recruiting | 1/2 | 40 | US | NRTX-1001, GABA-secreting interneurons, Sham Comparator | Neurona Therapeutics, California Institute for Regenerative Medicine (CIRM) | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | 05/25 | 05/26 | | |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
| Paul, Alexandra |
PICASSO, NCT05611242: Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial |
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| Recruiting | 3 | 404 | US | MT+CAS with IV-AP, Thrombectomy, MT+CAS with PO-AP, MT+CAT with PO-AP | Mercy Health Ohio | Acute Ischemic Stroke | 03/26 | 05/27 | | |
ROADS, NCT04365374: Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile- (Radiation One and Done Study) |
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| Recruiting | 3 | 180 | US | Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Carrier Tile Brachytherapy Therapy (CTBT), Stereotactic Radiation Therapy | GT Medical Technologies, Inc. | Brain Metastases | 12/25 | 12/27 | | |
| Recruiting | 2/3 | 200 | Europe, Canada, US | Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device, EmboTrap III, Initial medical management (iMM) | Emory University, University of Calgary, University of Cincinnati, Heidelberg University, Children's Hospital Medical Center, Cincinnati | Cerebral Ischemia | 12/24 | 12/24 | | |
NCT05362747: ProduceRx: Improving Weight and Cardiovascular Risk in Adults With Food Insecurity and Obesity |
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| Completed | N/A | 31 | US | Behavioral weight loss and produce vouchers | University of Pennsylvania | Obesity | 06/23 | 06/23 | | |
EMBOLISE, NCT04402632: Embolization of the Middle Meningeal Artery with ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma |
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| Active, not recruiting | N/A | 600 | US | Surgical Management, Surgical Management + Treatment, No Treatment, Treatment | Medtronic Neurovascular Clinical Affairs | Subdural Hematoma | 12/24 | 03/25 | | |
| Completed | N/A | 105 | US | BWL+VOUCHER, BWL+HOME, Behavioral weight loss counseling (BWL) | University of Pennsylvania, National Institute of Nursing Research (NINR) | Obesity, Food Insecurity | 07/24 | 07/24 | | |
WEB PAS, NCT04839705: Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device |
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| Recruiting | N/A | 180 | US | WEB | Microvention-Terumo, Inc. | Wide Neck Bifurcation Intracranial Aneurysms | 12/25 | 12/29 | | |
ARTISSE, NCT02998229: The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs). |
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| Recruiting | N/A | 220 | US | Artisse™ Intrasaccular Device | Medtronic Neurovascular Clinical Affairs | Intracranial Aneurysm | 02/28 | 02/32 | | |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
NCT05409989: MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study |
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| Recruiting | N/A | 154 | US | FRED™ X™, Flow Re-Direction Endoluminal Device X | Microvention-Terumo, Inc. | Intracranial Aneurysm | 09/29 | 11/29 | | |
| Recruiting | N/A | 40000 | Europe, Canada, Japan, US, RoW | Stroke/Thrombectomy/Aneurysm-specific surgical procedures | Medical University of South Carolina | Stroke, Thromboses, Intracranial, Aneurysm, Brain | 01/55 | 01/55 | | |
| Yao, Kevin |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
| David, Dubin |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
| Ahmed, Tuba |
WEB PAS, NCT04839705: Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device |
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| Recruiting | N/A | 180 | US | WEB | Microvention-Terumo, Inc. | Wide Neck Bifurcation Intracranial Aneurysms | 12/25 | 12/29 | | |
NCT04427384: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) |
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| Recruiting | N/A | 600 | US | GammaTile | GT Medical Technologies, Inc. | Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic, Brain Tumor, Adult: Glioblastoma, Brain Tumor, Adult Meningioma | 10/28 | 12/28 | | |
| Gaughan-Maher, Ashley E |
ROADS, NCT04365374: Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile- (Radiation One and Done Study) |
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| Recruiting | 3 | 180 | US | Gamma Tile-Surgically Targeted Radiation Therapy (STaRT), Carrier Tile Brachytherapy Therapy (CTBT), Stereotactic Radiation Therapy | GT Medical Technologies, Inc. | Brain Metastases | 12/25 | 12/27 | | |
| Recruiting | 1 | 6 | US | Olaparib, Lynparza, 17b-estradiol, Estrace | Mary D Chamberlin, Dartmouth-Hitchcock Medical Center | Metastatic Breast Cancer | 12/27 | 12/28 | | |
