The Royal Marsden NHS Foundation Trust (Chelsea Site)
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 19 Trials 
29 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Lee, Richard K
NCT03824119: Postpartum NSAIDS and Maternal Hypertension

Recruiting
4
200
US
Ibuprofen 600 mg, Standard Postpartum Care, Standard Postpartum Care without NSAIDs
University of Southern California
Preeclampsia, Gestational Hypertension, Superimposed Preeclampsia, Chronic Hypertension in Obstetric Context
12/22
12/22
NRG-BN003, NCT03180268: Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Recruiting
3
148
Canada, Japan, US, RoW
Clinical Observation, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, Irradiation, RADIATION, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation
NRG Oncology, National Cancer Institute (NCI)
Grade II Meningioma, Intracranial Meningioma
06/27
08/27
NRG-HN005, NCT03952585: De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Active, not recruiting
2/3
384
Canada, US
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Fludeoxyglucose F-18, 18FDG, FDG, Fludeoxyglucose (18F), fludeoxyglucose F 18, Fludeoxyglucose F18, Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, Fluorodeoxyglucose F18, Image Guided Radiation Therapy, IGRT, image-guided radiation therapy, Image-Guided Radiotherapy, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration
National Cancer Institute (NCI), NRG Oncology
Basaloid Squamous Cell Carcinoma, Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Oropharyngeal Squamous Cell Carcinoma, Papillary Squamous Cell Carcinoma, Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Squamous Cell Carcinoma
03/24
12/25
CIRCULATE-US, NCT05174169: Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Recruiting
2/3
1912
Canada, US
Signatera test, mFOLFOX6 3-6 month, CAPOX 3 month, mFOLFIRINOX, mFOLFOX6 6 month, CAPOX 6 month
NRG Oncology, Natera, Inc., National Cancer Institute (NCI)
Stage III Colon Cancer
03/29
03/30
NCT04824937: Telaglenastat + Talazoparib In Prostate Cancer

Not yet recruiting
2
30
US
Telaglenastat, CB 839, Talazoparib, Taken orally
Massachusetts General Hospital, Calithera Biosciences, Inc, Pfizer, Prostate Cancer Foundation
Prostate Cancer Metastatic
12/21
12/21
I-SPY_COVID, NCT04488081: I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

Recruiting
2
1500
US
Remdesivir, GS-5734, Imatinib Mesylate, Dexamethasone, Cenicriviroc, Icatibant, Firazyr, Apremilast, Otezla, dornase alfa, Pulmozyme, Celecoxib, celebrex, Famotidine, Pepcid, IC14, Aviptadil, Zyesami, narsoplimab, OMS721, Cyproheptadine, periactin, Cyclosporine, CsA
QuantumLeap Healthcare Collaborative, University of California, San Francisco, University of Pennsylvania, Emory University, University of Alabama at Birmingham, University of Colorado, Denver, University of Southern California, Yale University, Wake Forest University Health Sciences, Sanford Health, Long Beach Memorial Medical Center, Georgetown University, University of California, Davis, Hoag Memorial Hospital Presbyterian, Main Line Health, DHR Health Institute for Research and Development, University of California, Irvine, Corewell Health, Kaiser Permanente, University of Michigan, West Virginia University, University of Miami, University Hospitals Cleveland Medical Center, Virtua Health, M.D. Anderson Cancer Center
COVID-19
07/28
07/30
KEYNOTE B36, NCT04892472: EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer

Recruiting
2
100
US
NovoTTF-200T, Pembrolizumab (MK-3475) 200 mg
NovoCure GmbH, Merck Sharp & Dohme LLC
Non-small Cell Lung Cancer
07/24
12/26
NCT06041789: Effect of Acetylcholinesterase Inhibitors on Bone Metabolism

Recruiting
2
45
US
Donepezil, Placebo
Duke University, National Institute on Aging (NIA)
Osteoporosis
06/25
06/25
NCT06731894: Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Not yet recruiting
2
120
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cannabidiol, CBD, CBD Oil, Epidiolex, GWP42003-P, Dronabinol, (-)-.DELTA.9-Tetrahydrocannabinol, Abbott 40566, Delta(9)-Tetrahydrocannibinol, Delta-9-Tetrahydrocannabinol, Delta-9-THC, Delta9-THC, Marinol, SP 104, SP-104, SYNDROS, Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol, Tetrahydrocannabinol, THC, Placebo Administration, Survey Administration
City of Hope Medical Center, National Cancer Institute (NCI)
Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy, Colon Carcinoma
10/26
10/26
NCT04014205: A Study of Tyrosine Kinase Inhibitor Orelabrutinib (ICP-022) in Patients With r/r B-Cell Malignancies

Active, not recruiting
1/2
81
Europe, US, RoW
Orelabrutinib (ICP-022)
Beijing InnoCare Pharma Tech Co., Ltd.
Part 1：r/r B-cell Malignancies, Part 2：B-cell Malignancies
12/23
01/25
CELLO-1, NCT04179864 / 2019-003649-14: A Study of Tazemetostat With Enzalutamide or Abiraterone/Prednisone in Participants With Advanced Prostate Cancer

Checkmark Data from CELLO-1 trial for CRPC at SUO 2022
Dec 2022 - Dec 2022: Data from CELLO-1 trial for CRPC at SUO 2022
Checkmark Safety data from P1b portion of P1b/2 trial in combination with enzalutamide or with abiraterone/prednisone for CRPC at ESMO 2021
Sep 2021 - Sep 2021: Safety data from P1b portion of P1b/2 trial in combination with enzalutamide or with abiraterone/prednisone for CRPC at ESMO 2021
Terminated
1/2
102
Europe, US
Tazemetostat, EPZ-6438, E7438, IPN60200, Abiraterone/prednisone, Zytiga, Enzalutamide, Xtandi
Epizyme, Inc.
Metastatic Prostate Cancer, Metastatic Castration-resistant Prostate Cancer
11/24
11/24
KEYNOTE-E58, NCT04041310: Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors

Active, not recruiting
1/2
115
Europe, Canada, US
GAd-209-FSP low dose, MVA-209-FSP low dose, GAd-209-FSP high dose, MVA-209-FSP high dose, GAd20-209-FSP, RP2D, MVA-209-FSP, RP2D, KEYTRUDA®, pembrolizumab
Nouscom SRL, Merck Sharp & Dohme LLC
Solid Tumor, Adult
04/25
11/26
NCT04524962: Study of Descartes-30 in Acute Respiratory Distress Syndrome

Terminated
1
12
US
Descartes 30
Cartesian Therapeutics, National Heart, Lung, and Blood Institute (NHLBI)
Acute Respiratory Distress Syndrome, Covid19
09/22
09/23
NCT05672342: Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Withdrawn
1
120
US
Cannabidiol, CBD, CBD Oil, Epidiolex, GWP42003-P, Delta-8-Tetrahydrocannabinol, .DELTA.8-TETRAHYDROCANNABINOL, delta-8-THC, Placebo Administration, Questionnaire Administration
City of Hope Medical Center, National Cancer Institute (NCI)
Breast Carcinoma, Chemotherapy-Induced Peripheral Neuropathy, Colon Carcinoma
10/25
10/25
LIBRA, NCT04270799: Lung Nodule Imaging Biobank for Radiomics and AI Research

Recruiting
N/A
1000
Europe
Machine Learning Classification
Royal Marsden NHS Foundation Trust, RM Partners West London Cancer Alliance, Royal Brompton & Harefield NHS Foundation Trust, University College London Hospitals, Imperial College Healthcare NHS Trust, Lewisham and Greenwich NHS Trust, King's College Hospital NHS Trust, Epsom and St Helier University Hospitals NHS Trust, Institute of Cancer Research, United Kingdom, Guy's and St Thomas' NHS Foundation Trust, UCLH Biomedical Research Centre
Lung Cancer, Pulmonary Nodule, Multiple, Pulmonary Nodule, Solitary, Lung Neoplasms
08/21
08/21
NCT01961843: Abiraterone Acetate for Castrate Resistant Prostate Cancer

Active, not recruiting
N/A
40
US
Abiraterone, Abiraterone acetate, Zytiga, Prednisone
Massachusetts General Hospital
Prostate Cancer
06/24
12/24
NCT01961713: Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

Recruiting
N/A
200
US
Massachusetts General Hospital, Prostate Cancer Foundation Clinical Research Consortium
Prostate Cancer
12/25
12/25
NCT02862158: Frequency Doubling Technology (FDT) Mobile Visual Field Testing

Recruiting
N/A
500
US
FDT visual field, Standard HVF
University of Miami
Glaucoma
11/22
11/22
AI-SONAR, NCT05375591: AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer

Recruiting
N/A
1000
Europe
Non-Interventional Study
Royal Marsden NHS Foundation Trust, Institute of Cancer Research, United Kingdom, National Institute for Health Research, United Kingdom, Royal Brompton & Harefield NHS Foundation Trust, Royal Marsden Partners Cancer Alliance, Imperial College London, Oxford University Hospitals NHS Trust, National Heart and Lung Institute
Indeterminate Pulmonary Nodules, Lung Metastases, Second Primary Cancer, Lung Cancer
11/22
11/26
NCT04957433: 'Lung Health Check' Biomarker Study

Recruiting
N/A
1000
Europe
Blood Specimen, Sputum Specimen
Royal Marsden NHS Foundation Trust, Royal Brompton & Harefield NHS Foundation Trust, Imperial College London, Royal Marsden Partners Cancer Alliance
Lung Cancer, Cancer
12/23
12/23
SCOOT, NCT05368298: Sample Collection for DART

Recruiting
N/A
5000
Europe
University of Oxford, Innovate UK, Optellum, National Institute for Health Research, United Kingdom, Cancer Research UK, GE Healthcare, RNA Guardian, Roche Diagnostics GmbH
Lung Cancer
02/25
02/25
PILLCAM, NCT06712095: Video Capsule Examination in Patients With Lynch Syndrome

Recruiting
N/A
25
Europe
Video capsule investigation, Colonoscopy
Royal Marsden NHS Foundation Trust, King's College London
Lynch Syndrome, Li Fraumeni Syndrome, PTEN Hamartoma Syndrome, FAP, MUTYH Biallelic Mutation, STK11 Mutation, CDH1 Gene Mutation, CHEK2 Gene Mutation, BMPR1A Gene Mutation, SMAD4 Gene Mutation
10/25
10/25
DOLCE, NCT05389774: Determining the Impact of Optellum's Lung Cancer Prediction Solution

Recruiting
N/A
2000
Europe
Nottingham University Hospitals NHS Trust, Optellum Ltd.
AI (Artificial Intelligence), Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple, Lung Cancer
01/25
01/25
NCT06500377: Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors

Recruiting
N/A
44
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Meditation Therapy, Meditation, Questionnaire Administration
City of Hope Medical Center, National Cancer Institute (NCI)
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
06/26
06/26
NCT03615794: A Study of Pregnant and Postpartum Women With and Without Mood Disorders

Active, not recruiting
N/A
400
US
Johns Hopkins University, University of Virginia
Bipolar Disorder, Major Depressive Disorder, Postpartum Depression, Postpartum Psychosis
01/24
12/25
NCT06581211: Aromatherapy Oil Associated for Managing Anxiety and Pain During Bone Marrow Biopsy Procedures

Recruiting
N/A
45
US
Aromatherapy and Essential Oils, Aromatherapy, Electronic Health Record Review, Jojoba Oil, Lavender Oil, Common Lavender Oil, English Lavender Oil, Lavandula officinalis Flowering Top Oil, Questionnaire Administration
City of Hope Medical Center, National Cancer Institute (NCI)
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
12/28
12/28
NCT05876676: RDC Biomarker Study

Not yet recruiting
N/A
1000
NA
Royal Marsden NHS Foundation Trust
Cancer
04/25
04/26
NIMBLE, NCT05432739: Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study

Recruiting
N/A
500
Europe
Royal Marsden NHS Foundation Trust, Royal Brompton & Harefield NHS Foundation Trust, Royal Marsden Partners West London Cancer Alliance, Imperial College London, University College London Hospitals, Lewisham and Greenwich NHS Trust, Guy's and St Thomas' NHS Foundation Trust, Epsom and St Helier University Hospitals NHS Trust, King's College Hospital NHS Trust, University College London (UCL) Cancer Institute, Institute of Cancer Research, United Kingdom, Francis Crick Institute, Royal Sussex County Hospital
Lung Cancer
01/26
01/31
Jain, Sejal
AI-SONAR, NCT05375591: AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer

Recruiting
N/A
1000
Europe
Non-Interventional Study
Royal Marsden NHS Foundation Trust, Institute of Cancer Research, United Kingdom, National Institute for Health Research, United Kingdom, Royal Brompton & Harefield NHS Foundation Trust, Royal Marsden Partners Cancer Alliance, Imperial College London, Oxford University Hospitals NHS Trust, National Heart and Lung Institute
Indeterminate Pulmonary Nodules, Lung Metastases, Second Primary Cancer, Lung Cancer
11/22
11/26

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