| Completed | N/A | 4318 | US | Trial Mailed FIT Intervention - Age Group 50-75, Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49, Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49 | UNC Lineberger Comprehensive Cancer Center, National Cancer Institute (NCI), East Carolina University | Colorectal Cancer | 03/23 | 09/24 | | |