UCSF Neurosciences Clinical Research Unit (NCRU)
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 5 Trials 
13 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Boxer, Adam L
NCT03260920: Intranasal Oxytocin for Frontotemporal Dementia

Active, not recruiting
2
112
Canada, US
Syntocinon, Intranasal Oxytocin
Lawson Health Research Institute, Weston Brain Institute, Canadian Institutes of Health Research (CIHR), Berry Consultants
Frontotemporal Dementia
06/23
12/24
SAL-AD, NCT03277573: Salsalate in Patients Mild to Moderate Alzheimer's Disease

Active, not recruiting
1b
40
US
Salsalate, Placebo
Adam Boxer
Alzheimer Disease
04/21
12/21
4RTNI-2, NCT02966145: 4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2

Active, not recruiting
N/A
232
Canada, US
Observational Study
University of California, San Francisco, National Institutes of Health (NIH), National Institute on Aging (NIA)
Corticobasal Degeneration (CBD), Corticobasal Syndrome (CBS), Cortical-basal Ganglionic Degeneration (CBGD), Progressive Supranuclear Palsy (PSP), Nonfluent Variant Primary Progressive Aphasia (nfvPPA), Oligosymptomatic/Variant Progressive Supranuclear Palsy (o/vPSP)
12/24
12/24
4RTNI, NCT01804452: 4 Repeat Tauopathy Neuroimaging Initiative

Active, not recruiting
N/A
110
US
Observational Study
University of California, San Francisco, National Institutes of Health (NIH), National Institute on Aging (NIA)
Progressive Supranuclear Palsy, Corticobasal Degeneration
12/24
12/24
NCT04363684: ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

Recruiting
N/A
2100
Canada, US
Mayo Clinic, University of California, San Francisco, National Institute on Aging (NIA), National Institute of Neurological Disorders and Stroke (NINDS)
Frontotemporal Lobar Degeneration (FTLD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), Behavioral Variant Frontotemporal Dementia (bvFTD), Semantic Variant Primary Progressive Aphasia (svPPA), Nonfluent Variant Primary Progressive Aphasia (nfvPPA), FTD With Amyotrophic Lateral Sclerosis (FTD/ALS), Amyotrophic Lateral Sclerosis, Oligosymptomatic PSP (oPSP), C9orf72, GRN Related Frontotemporal Dementia, MAPT Gene Mutation, TBK1 Gene Mutation, Oligosymptomatic Progressive Supranuclear Palsy
06/25
06/25
NCT06774183: Effect of Presbyopia Correction on Livelihood and Repayment Among Solar Customers in Western Region, Kenya

Not yet recruiting
N/A
1085
NA
Near vision glasses for presbyopia correction
Dot Glasses Kenya, Queen's University Belfast, UK, University of Stellenbosch, Sun King, Livelihood Impact Fund
Presbyopia Correction, Visual Impairment and Blindness (Excl Colour Blindness), Repayment Behaviour, Livelihoods
08/25
09/25
NCT04516499: Neurofilament Surveillance Project (NSP)

Active, not recruiting
N/A
342
US
The Bluefield Project to Cure Frontotemporal Dementia, Mayo Clinic, University of California, San Francisco
Frontotemporal Dementia, Frontotemporal Lobar Degeneration, FTD-GRN, FTD, FTLD
02/27
02/27
Ljubenkov, Peter
INFRONT-3, NCT04374136 / 2019-004066-18: A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia

Active, not recruiting
3
110
Europe, Canada, US, RoW
AL001, Placebo, Open label - AL001
Alector Inc.
Frontotemporal Dementia
09/25
10/27
ROCKIT-1, NCT04734379: Rho Kinase (ROCK) Inhibitor in Tauopathies - 1

Active, not recruiting
2a
15
US
Fasudil
Woolsey Pharmaceuticals
Progressive Supranuclear Palsy, Corticobasal Syndrome
11/22
11/23
NCT04993755 / 2021-002251-11: A Phase 2a Study of TPN-101 in Patients With C9ORF72 ALS/FTD

Active, not recruiting
2a
42
Europe, US
TPN-101, 400 mg/day, Placebo
Transposon Therapeutics, Inc., Transposon Therapeutics, Inc
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
09/23
09/23
INFRONT-2, NCT03987295 / 2019-000138-20: A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients

Completed
2
33
Europe, Canada, US
AL001
Alector Inc., GlaxoSmithKline
Frontotemporal Dementia
06/24
06/24
Veri-T-001, NCT05184569: Veri-T: A Trial of Verdiperstat in Patients With svPPA Due to TDP-43 Pathology

Recruiting
1
64
US
Verdiperstat, BHV-3241
Peter Ljubenkov, MD, National Institutes of Health (NIH), Alzheimer's Association, National Institute on Aging (NIA)
Semantic Dementia
06/26
09/26
ADNI3, NCT02854033: Alzheimer's Disease Neuroimaging Initiative 3

Recruiting
N/A
2000
Canada, US
University of Southern California, Northern California Institute of Research and Education, National Institute on Aging (NIA), Alzheimer's Therapeutic Research Institute
Mild Cognitive Impairment (MCI), Alzheimer's Disease (AD)
12/24
12/24

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