| Ishkanian, Adrian |
SABR-COMET-3, NCT03862911: Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer |
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| Recruiting | N/A | 330 | Europe, Canada, RoW | palliative radiotherapy, Stereotactic ablative radiotherapy | British Columbia Cancer Agency, London Regional Cancer Program, Canada, The Alfred, Beacon Hospital, Ireland, Cancer Trials Ireland, Cancer Research UK Edinburgh Centre, Bon Secours Cork Cancer Centre, UPMC Hillman Cancer Centre, Beatson West of Scotland Cancer Centre, Tom Baker Cancer Centre, Walker Family Cancer Centre, Riverina Cancer Care Centre | Metastatic Tumors | 09/30 | 09/30 | | |
| Palma, David |
| Active, not recruiting | 3 | 204 | Europe, Canada, RoW | Palliative Radiation, Palliative Radiotherapy, Chemotherapy, Immunotherapy, Hormones, Observation, Stereotactic Ablative Radiotherapy | David Palma, Amsterdam University Medical Centre, VUmc Site, British Columbia Cancer - Centre for the North, Beaston West of Scotland Cancer Centre, London Health Sciences Centre | Metastatic Tumors | 01/29 | 01/29 | | |
SABR-SYNC, NCT05717166: A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor. |
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| Recruiting | 3 | 180 | Canada | Palliative Radiotherapy, Chemotherapy, Cytotoxic Systemic Therapy, Hormone therapy, Hormonal Systemic Therapy, Immunotherapy, Targeted Systemic Therapy, Observation, Stereotactic Ablative Radiotherapy, Surgery, Radiofrequency Therapy (RFA), Fractionated Radiation | David Palma | Metastatic Tumor | 04/29 | 04/29 | | |
MISSILE, NCT02136355: A Phase II Trial Measuring the Integration of Stereotactic Radiotherapy Plus Surgery in Early Non-Small Cell Lung Cancer |
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| Completed | 2 | 40 | Canada | Stereotactic Body Radiation Therapy plus Surgery | Lawson Health Research Institute | Non Small Cell Lung Cancer | 11/22 | 11/22 | | |
ORATOR, NCT01590355: A Phase II Randomized Trial for Early-stage Squamous Cell Carcinoma of the Oropharynx: Radiotherapy vs Trans-oral Robotic Surgery |
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| Active, not recruiting | 2 | 68 | Canada, RoW | Radiotherapy, Transoral Robotic Surgery + Neck Dissection | Lawson Health Research Institute | Early-Stage Squamous Cell Carcinoma of the Oropharynx | 09/23 | 09/23 | | |
| Completed | 2 | 49 | Canada | Opioids, PAiN - multimodal analgesia | Lawson Health Research Institute, Ontario Institute for Cancer Research | Head and Neck Cancer, Radiation-Induced Mucositis | 09/23 | 09/23 | | |
| Recruiting | 2 | 106 | Canada | SABR boost and de-escalated chemoradiation, Standard chemoradiation | Centre hospitalier de l'Université de Montréal (CHUM), M.D. Anderson Cancer Center, Lawson Health Research Institute, Jewish General Hospital | Head and Neck Cancer, Oropharynx Cancer, Human Papilloma Virus | 12/24 | 12/26 | | |
| Recruiting | 2 | 155 | Canada, US | Vocal-cord Radiotherapy, Complete Larynx Radiotherapy | Centre hospitalier de l'Université de Montréal (CHUM), London Health Sciences Centre, M.D. Anderson Cancer Center | Cancer Neck, Larynx Cancer, Glottis Tumor | 10/24 | 07/26 | | |
| Active, not recruiting | 2 | 99 | Europe, Canada, RoW | Stereotactic ablative radiotherapy, palliative radiotherapy | Lawson Health Research Institute, London Regional Cancer Program, Canada, VU University of Amsterdam | Metastatic Tumors | 06/26 | 06/26 | | |
| Recruiting | 2 | 98 | Canada | N-Acetyl cysteine, NAC, Dexamethasone Oral, Corticosteroid, N-Acetyl cysteine Placebo, NAC Placebo, Dexamethasone Placebo, Corticosteroid Placebo, Radiation Therapy | David Palma, London Health Sciences Centre, Centre Hospitalier de l'Universite de Montreal (CHUM) | Lung Cancer, Interstitial Lung Disease | 07/28 | 12/32 | | |
| Not yet recruiting | 1 | 48 | NA | stereotactic body radiation therapy (SBRT), Radiation therapy | Lawson Health Research Institute | Thoracic Cancer, Lung Cancer, Esophageal Cancer | 10/26 | 01/27 | | |
NCT04852588: Chest Lymph Node Sampling in Patients With Advanced Lung Cancer to be Treated With Curative-intent Radiation Treatment |
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| Recruiting | N/A | 29 | Canada | Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TFNA), Transesophageal ultrasound-guided fine needle aspiration (EUS-FNA) | Lawson Health Research Institute, Academic Medical Organization of Southwestern Ontario | Non-Small Cell Lung Cancer | 05/25 | 05/25 | | |
DART, NCT05233904: Diagnostic-CT-Enabled Planning: A Randomized Trial in Palliative Radiation Therapy |
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| Recruiting | N/A | 33 | Canada | Diagnostic-CT-enabled Planning, Standard of Care | Lawson Health Research Institute | Advanced Cancer Requiring Palliative Radiation | 06/23 | 08/23 | | |
| Active, not recruiting | N/A | 39 | Europe, Canada | Stereotactic Ablative Radiotherapy | Lawson Health Research Institute, London Health Sciences Centre, University of British Columbia, Western University, Canada | Non Small Cell Lung Cancer, Interstitial Lung Disease | 01/22 | 09/26 | | |
NCT05314946: Nutritional Support During Induction Therapy for Esophageal Cancer |
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| Recruiting | N/A | 26 | Canada | No feeding tube placed, Placement of a percutaneous feeding tube | Mehdi Qiabi | Esophageal Cancer, Nutrition Aspect of Cancer | 09/24 | 12/24 | | |
RT-NOW, NCT06156800: Is Radiation-before-pathology a Feasible Approach in the Palliative Oncology Setting? A Pragmatic Clinical Trial |
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| Recruiting | N/A | 48 | Canada | | David Palma | Cancer | 05/25 | 02/26 | | |
PET-BOOST, NCT02788461: Assessing the Efficacy and Safety of Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non-Small Cell Lung Cancer Receiving Definitive Chemoradiotherapy |
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| Active, not recruiting | N/A | 78 | Canada | Chemoradiotherapy, Chemoradiotherapy with Integrated Boost Dose | Lawson Health Research Institute | Non-Small Cell Lung Cancer | 04/25 | 04/25 | | |
ORATOR2, NCT03210103: Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer |
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| Active, not recruiting | N/A | 61 | Canada, RoW | Radiation, Chemotherapy, if required, Transoral Surgery (TOS) + Neck Dissection, Radiation, if required | Lawson Health Research Institute | Oropharyngeal Cancer | 08/28 | 08/28 | | |
SABR-COMET-3, NCT03862911: Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic (1-3 Metastases) Cancer |
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| Recruiting | N/A | 330 | Europe, Canada, RoW | palliative radiotherapy, Stereotactic ablative radiotherapy | British Columbia Cancer Agency, London Regional Cancer Program, Canada, The Alfred, Beacon Hospital, Ireland, Cancer Trials Ireland, Cancer Research UK Edinburgh Centre, Bon Secours Cork Cancer Centre, UPMC Hillman Cancer Centre, Beatson West of Scotland Cancer Centre, Tom Baker Cancer Centre, Walker Family Cancer Centre, Riverina Cancer Care Centre | Metastatic Tumors | 09/30 | 09/30 | | |
