Zhang, Wei |
NCT04504864: Low-dose Aspirin Therapy in Patients With Ischemic Stroke and Microbleeds |
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| Recruiting | 4 | 400 | RoW | low-dose aspirin, conventional-does aspirin | Xijing Hospital, Shaanxi Provincial People's Hospital, The First Affiliated Hospital of Jiaotong University, Tang-Du Hospital, The First Affiliated Hospital of Xi'an Medical University, Xi'an Central Hospital, Xiangyang Central Hospital, Baoji Central Hospital | Ischemic Stroke | 02/22 | 08/22 | | |
| Active, not recruiting | 4 | 130 | RoW | Dexamethasone lipid microsphere plus ropivacaine, ropivacaine plus D-PAL, Ropivacaine alone | Beijing Tiantan Hospital | Pain, Postoperative | 09/23 | 12/23 | | |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease |
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| Recruiting | 4 | 1312 | RoW | GV-971, Placebo | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer's Disease | 06/29 | 12/29 | | |
NCT04504396: Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy |
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| Completed | 3 | 620 | RoW | GLP-1 receptor agonist, Placebo, PB-119 Placebo | PegBio Co., Ltd. | Type 2 Diabetes Mellitus (T2DM) | 09/22 | 05/23 | | |
NCT04683406: A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A |
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| Completed | 3 | 750 | RoW | ZSP1273 600 mg, Placebo to Oseltamivir, Oseltamivir(oral), Placebo to ZSP1273 | Guangdong Raynovent Biotech Co., Ltd | Influenza A | 04/23 | 05/23 | | |
NCT06103825: A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients With Obstructive Sleep Apnea (OSA) |
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| Recruiting | 3 | 204 | RoW | Solriamfetol, Placebo | Ignis Therapeutics (Suzhou) Limited | Excessive Daytime Sleepiness Associated With Obstructive Sleep Apnea | 09/24 | 10/24 | | |
| Recruiting | 3 | 1200 | Europe, Canada, Japan, US, RoW | Remternetug, LY3372993, Placebo | Eli Lilly and Company | Alzheimer's Disease | 04/29 | 10/30 | | |
| Recruiting | 3 | 1500 | Europe, RoW | Donanemab, (LY3002813), Placebo | Eli Lilly and Company | Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders | 04/27 | 04/27 | | |
NCT05215379: Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer |
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| Recruiting | 2/3 | 180 | RoW | xintilimab injection, Control | Changhai Hospital | Neoadjuvant Chemoradiation Therapy, Rectal Cancer, Immunotherapy, Microsatellite Instability Low | 10/24 | 04/25 | | |
NCT05811442: Study of 50561 in Patients With Mild or Moderate Alzheimer's Disease |
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| Recruiting | 2a | 60 | RoW | 50561 high dose, 50561 low dose, Placebo | Beijing Joekai Biotechnology LLC | Alzheimer's Disease | 05/24 | 06/24 | | |
NCT03746223: Intravitreal Methotrexate and R2(Rituximab & Lenalidomide) Regimen in Newly-diagnosed Primary Vitreoretinal Lymphoma |
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| Recruiting | 2 | 42 | RoW | Methotrexate, Rituximab, Lenalidomide | Peking Union Medical College Hospital | Primary Intraocular Lymphoma | 11/20 | 10/25 | | |
NCT05229029: RSYR for Fatigue Reduction in Cancer Fatigue Caused by Chemotherapy |
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| Active, not recruiting | 2 | 196 | RoW | TCM Formula, RSYR decoction, Placebo, Placebo dicoction | Peking University Cancer Hospital & Institute | Cancer-related Problem/Condition | 09/23 | 06/24 | | |
NCT04899427: Phase II Study of Orelabrutinib Combined With PD-1 Inhibitor in Relapsed/Refractory Primary Central Nervous System Lymphoma |
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| Recruiting | 2 | 32 | RoW | orelabrutinib, Sintilimab, Tislelizumab | Peking Union Medical College Hospital, Beijing Hospital, Beijing Tongren Hospital, Beijing Luhe Hospital, Shanxi Province Renmin Hospital, Henan Cancer Hospital, Henan Province Renmin Hospital, The Second Affiliated Hospital of Dalian Medical University, The Forth Hospital of Hebei Medical University, The First Hospital of Chinese Medical University, Qilu Hospital of Shandong University, The First Hospital of Zhengzhou University | Primary Central Nervous System Lymphoma | 03/23 | 10/23 | | |
NCT06259526: A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression |
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| Recruiting | 2 | 260 | RoW | Placebo group, JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 low-dose group, JS1-1-01 pills; JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 pills; JS1-1-01 placebo pills, JS1-1-01 high-dose group, JS1-1-01 pills; Duloxetine hydrochloride placebo capsules, Active drug group, JS1-1-01 placebo pills; Duloxetine hydrochloride enteric coated capsule | Tasly Pharmaceutical Group Co., Ltd | Depression | 04/25 | 04/25 | | |
NCT05179213: Azacytidine Plus Chidamide in the Treatment of Relapsed and Refractory Angioimmunoblastic T-cell Lymphoma |
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| Not yet recruiting | 2 | 20 | RoW | Azacitidine, Chidamide | Peking Union Medical College Hospital, Beijing Longfu Hospital | Angioimmunoblastic T-cell Lymphoma | 01/24 | 05/24 | | |
NCT06093841: Relmacabtagene Autoleucel as Second-Line Therapy in Adult Patients With Aggressive B-cell NHL |
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| Not yet recruiting | 2 | 46 | RoW | Relmacabtagene Autoleucel, JWCAR029, Fludarabine, Cyclophosphamide | Shanghai Ming Ju Biotechnology Co., Ltd. | Lymphoma, Large B-Cell, Diffuse, Follicular Lymphoma Grade 3B, High-grade B-cell Lymphoma, Mediastinal B-Cell Diffuse Large Cell Lymphoma | 08/24 | 02/27 | | |
NCT05555901: The Efficacy and Safety of Fruquintinib Plus Chemotherapy as Second-line Treatment in Metastatic Colorectal Cancer |
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| Recruiting | 2 | 116 | RoW | Fruquintinib+ chemotherapy, Bevacizumab+ chemotherapy | Fudan University | Metastatic Colorectal Cancer | 09/25 | 09/25 | | |
NCT02987244: Chidamide Plus CHOEP Combined With Upfront ASCT in Untreated Peripheral T-cell Lymphoma |
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| Recruiting | 1/2 | 100 | RoW | Chidamide, epidaza, Cyclophosphamide, Epirubicin, Vindesine, Etoposide, Prednisone | Peking Union Medical College Hospital, Chinese PLA General Hospital, Peking University First Hospital, Peking University Third Hospital, Peking University Cancer Hospital & Institute, Tianjin Medical University Cancer Institute and Hospital | T Cell Non-Hodgkin's Lymphoma | 03/20 | 03/23 | | |
GLORY, NCT04270591: Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer |
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| Recruiting | 1/2 | 183 | Japan, US, RoW | Glumetinib, SCC244 | Haihe Biopharma Co., Ltd. | C-Met Exon 14 Mutation | 10/23 | 12/23 | | |
NCT05464433: Tislelizumab Combined With Mitoxantrone Hydrochloride Liposome in Extranodal Natural Killer/T Cell Lymphoma |
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| Recruiting | 1/2 | 46 | RoW | Tislelizumab combined with Liposomal mitoxantrone hydrochloride, Maintenance of tislelizumab | Sun Yat-sen University | Extranodal Natural Killer T Cell Lymphoma | 01/24 | 01/25 | | |
| Recruiting | 1/2 | 120 | RoW | Chidamide, HDACi, Fludarabine and cyclophosphamide, FC regimen, Anti-CD19 CAR-T cells, Relma-cel, Axi-cel, Other commercial CAR-T cells, Experimental CAR-T cells | Chinese PLA General Hospital | Non Hodgkin's Lymphoma | 06/24 | 06/25 | | |
NCT06393413: To Explore the Therapeutic Potential of Jiedu Yizhi Formula for Alzheimer 's Disease |
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| Completed | 1 | 62 | RoW | Jiedu Yizhi Formula, Donepezil Hydrochloride Tablets | Changchun University of Chinese Medicine | Ensure the Legality and Compliance of the Testing Process | 12/23 | 04/24 | | |
NCT05240950: Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases |
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| Recruiting | 1 | 18 | RoW | Anti-CEA CAR-T Cells | Changhai Hospital | Colorectal Cancer, Metastatic Liver Cancer | 12/23 | 12/26 | | |
NCT05577091: Tris-CAR-T Cell Therapy for Recurrent Glioblastoma |
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| Recruiting | 1 | 10 | RoW | Inverse correlated dual-target, truncated IL7Ra modified CAR -expressing autologous T-lymphocytes., Autologous Tris-CAR-T cell. | Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Tasly Pharmaceutical Group Co., Ltd | Recurrent Glioblastoma | 11/24 | 11/32 | | |
NCT06515938: Study on New Strategies for Hepatitis B Virus Immunization |
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| Completed | N/A | 1169 | RoW | 20μg Engerix-B hepatitis B vaccine, 20μg Kangtai hepatitis B vaccine, 60μg Kangtai hepatitis B vaccine, 20μg CHO | Wu Jiang | Vaccine Reaction | 06/14 | 12/15 | | |
NCT05159804: Association Between Carotid Plaque Length and Cardiovascular Events |
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| Active, not recruiting | N/A | 3637 | RoW | | Changhai Hospital, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine | Coronary Arteriosclerosis | 06/21 | 12/30 | | |
| Recruiting | N/A | 630 | Europe, US, RoW | ROX index algorithm | Hospital Universitari Vall d'Hebron Research Institute | Acute Hypoxemic Respiratory Failure | 12/24 | 06/25 | | |
NCT05843487: Association Between Carotid Plaque Length and Cardiovascular Outcomes |
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| Active, not recruiting | N/A | 3000 | RoW | | Changhai Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital | Coronary Artery Disease, Carotid Plaque | 03/22 | 12/30 | | |
NCT03958435: Real-world Retrospective Data Analysis of Adjuvant Therapy for Patients With Stage II-III Colon Cancer After Radical Surgery |
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| Recruiting | N/A | 20000 | RoW | | Second Affiliated Hospital, School of Medicine, Zhejiang University | Stage II Colon Cancer, Stage III Colon Cancer, Adjuvant Therapy | 10/22 | 12/23 | | |
| Recruiting | N/A | 10254 | RoW | | Limeng Chen | Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder | 12/24 | 12/24 | | |
NCT05485857: Influence of Arrangement of Small Intestine Order on the Recovery of Bowel Function After Laparoscopic Colorectal Surgery |
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| Completed | N/A | 160 | RoW | Arrangement of small intestine order before close the abdomen | Changhai Hospital | Postoperative Complications | 02/23 | 03/23 | | |
NCT05634473: A Study to Evaluate the Sensitivity and Specificity of Inhaled Methacholine in Bronchial Provocation Test |
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| Not yet recruiting | N/A | 280 | RoW | Methacholine Chloride | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Asthma | 02/23 | 06/23 | | |
NCT04853238: Chronic Obstructive Pulmonary Disease (COPD) Maintenance Treatment Patterns in China |
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| Completed | N/A | 1507 | RoW | Prospective observational cohort study | GlaxoSmithKline | Pulmonary Disease, Chronic Obstructive | 11/22 | 02/23 | | |
ZCFZZLXGBDFYHZ, NCT05692258: Acupuncture as an Adjunctive Therapy for Covid-19 Omicron Randomised Controlled Trial in Patients With Moderate/Severe Pneumonia |
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| Recruiting | N/A | 146 | RoW | Acupuncture, basic therapy | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Acupuncture, Covid-19 Omicron, Pulmonary Function | 04/23 | 04/23 | | |
NCT05752097: [18F]AlF-NOTA-FAPI-04 PET/CT in Inflammation and Fibrosis in Renal Diseases |
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| Recruiting | N/A | 30 | RoW | [18F]AlF-NOTA-FAPI-04 PET/CT examination, Renal puncture biopsy | Sichuan Provincial People's Hospital | 18F-FAPI PET/CT Examination, Renal Puncture Biopsy | 08/24 | 11/24 | | |
GJZLBQGNZA, NCT05749354: Clinical Efficacy of Acupuncture on the Liver Meridian in Men With Erectile Dysfunction Reserve |
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| Recruiting | N/A | 159 | RoW | electroacupuncture, acupuncture | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Erectile Dysfunction, Acupuncture Therapy, Median Nerve Disease | 12/23 | 12/23 | | |
PCOS, NCT04984070: Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety |
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| Recruiting | N/A | 100 | RoW | Oral Contraceptives, Combined, Danie-35, Drospirenone and Ethinylestradiol Tablets (I), Drospirenone and Ethinylestradiol Tablets (Ⅱ), Metformin Pill, Metformin, lifestyle intervention | Fudan University | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety | 12/23 | 12/24 | | |
NCT05183425: Patient-derived Organoids Predicts the Clinical Efficiency of Colorectal Liver Metastasis |
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| Recruiting | N/A | 60 | RoW | | Changhai Hospital | Explore the Consistency of Drug Sensitivity Between Primary Colorectal Cancer and Liver Metastases | 12/23 | 12/24 | | |
| Recruiting | N/A | 198 | RoW | electropuncture, acupuncture | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Ovarian Reserve, Acupuncture Therapy, Meridian | 12/23 | 12/23 | | |
NCT05815069: [18F]AlF-NOTA-pentixather PET/CT in Patients With Suspected Primary Hyperaldosteronism |
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| Recruiting | N/A | 20 | RoW | [18F]AlF-NOTA-pentixather PET/CT, pathological examination | Sichuan Provincial People's Hospital | Aldosterone-Producing Adenoma | 01/24 | 06/24 | | |
| Recruiting | N/A | 20 | RoW | Glofitamab | Peking Union Medical College Hospital | DLBCL - Diffuse Large B Cell Lymphoma | 12/27 | 12/28 | | |
NCT06254716: A Study on the Prognosis of Two Different Surgery Methods in Patients With Rectal Endometriosis |
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| Recruiting | N/A | 90 | RoW | disc resection, segmental resection | Fudan University | Gastrointestinal Function, Quality of Life, Pregnancy Outcomes | 12/24 | 12/24 | | |
proOMCRC, NCT04716257: A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients |
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| Recruiting | N/A | 400 | RoW | | West China Hospital, Sun Yat-sen University, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Changhai Hospital, Naval Medical University | Ovarian Metastasis, Colorectal Cancer | 09/25 | 09/25 | | |
NCT06204497: The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients |
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| Recruiting | N/A | 570 | RoW | Stent-based Diverting Technique | Sir Run Run Shaw Hospital | Rectal Neoplasms | 12/24 | 06/25 | | |
VERONICA, NCT05486923: Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population |
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| Recruiting | N/A | 450 | RoW | | Huashan Hospital | Glioma, Patient Reported Outcome Measures, Self Report, Adverse Effects | 04/25 | 12/25 | | |
NCT05882552: Tilted Gaze Target Test in the Examination of Children With Superior Oblique Muscle Palsy |
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| Not yet recruiting | N/A | 80 | NA | Tilted Gaze Target Tast, Conventional Examination Methods | Tianjin Eye Hospital | Children With Torticollis | 06/24 | 12/24 | | |
NCT06510127: An AI Model Predicts the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer: a Multicenter, Bidirectional Cohort Study |
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| Enrolling by invitation | N/A | 840 | RoW | | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Jinan University | Breast Cancer | 06/25 | 01/26 | | |
NCT03651986: Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules |
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| Active, not recruiting | N/A | 10560 | RoW | ctDNA methylation analysis by NGS | AnchorDx Medical Co., Ltd., Xiangya Hospital of Central South University, West China Hospital, Shanghai Zhongshan Hospital, Shanghai Pulmonary Hospital affiliated to Tongji University, First Hospital of China Medical University, Guizhou Provincial People's Hospital, Shanghai Chest Hospital, First Affiliated Hospital, Sun Yat-Sen University, First Affiliated Hospital Xi'an Jiaotong University, Qilu Hospital of Shandong University, Inner Mongolia People's Hospital, The First Affiliated Hospital with Nanjing Medical University, The First Affiliated Hospital of Zhengzhou University, Second Hospital of Jilin University, LanZhou University, Peking University Third Hospital, The First People's Hospital of Yunnan, Shantou Affiliated Hospital of Sun Yat-Sen University, Ruijin Hospital, The Shanghai Jiao Tong University Medical School, Tongji Hospital, The First Affiliated Hospital of Guangzhou Medical University, Xijing Hospital, Air Force Medical University of PLA, Shenzhen People's Hospital, Henan Provincial People's Hospital, Beijing Chao Yang Hospital, Xiamen Second Hospital, The First Affiliated Hospital of Nanchang University | Pulmonary Nodules | 09/24 | 06/25 | | |
NCT05514327: A Study of Ultra-fraction Radiotherapy Bridging CART in R/R DLBCL |
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| Recruiting | N/A | 20 | RoW | ultra-fraction radiotherapy | Peking Union Medical College Hospital | Diffuse Large B Cell Lymphoma, CAR-T, Radiotherapy, Bridging Therapy | 09/24 | 12/24 | | |
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM). |
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| Not yet recruiting | N/A | 1000 | RoW | Continuous Glucose Monitoring System (GX-01S) | Nanjing First Hospital, Nanjing Medical University | Type1 Diabetes Mellitus | 10/26 | 06/27 | | |
NCT04837222: A Study of Brentuximab Vedotin in Adults With CD30-positive Lymphoma |
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| Active, not recruiting | N/A | 1000 | RoW | No Intervention | Takeda | Lymphoma | 06/26 | 06/26 | | |
NCT06723366: Protective Effect of Angong Niuhuang Against Negative Inflammatory Response and Neurologic Dysfunction After Cardiovascular Surgery |
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| Not yet recruiting | N/A | 120 | RoW | Angong Niuhuang Pill (ANP), Control (Standard treatment) | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University, Beijing Anzhen Hospital, Capital Medicine University | Cardio-pulmonary Bypass, Cardiovascular Surgery, Cerebral Protection, Brain Injury | 12/25 | 12/25 | | |
NCT05818267: Efficacy and Safety of Regorafenib Maintenance Therapy in Patients With Metastatic Colorectal Cancer (mCRC) |
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| Recruiting | N/A | 30 | RoW | Regorafenib | Wei Zhang | Colorectal Cancer | 03/25 | 11/25 | | |
NCT05282095: Effect of HPV Integration on Prognosis of Young Women With CIN2 in China |
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| Recruiting | N/A | 300 | RoW | Follow up | Fujian Maternity and Child Health Hospital | Cervical Intraepithelial Neoplasia, HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions | 12/25 | 05/26 | | |
AIM, NCT05032053: Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds |
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| Recruiting | N/A | 3000 | RoW | Antithrombotic drugs | Xijing Hospital, Ankang Central Hospital, Yan'an University Affiliated Hospital | Ischemic Stroke | 12/25 | 10/26 | | |
LPS-IHH, NCT05569577: An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients |
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| Recruiting | N/A | 46 | RoW | Additional hCG injection, estrogen and dydrogesterone | Fudan University | Luteal Phase Deficiency, Luteal Phase Support, Idiopathic Hypogonadotropic Hypogonadism | 12/25 | 12/25 | | |
NCT05923255: LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer |
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| Recruiting | N/A | 568 | RoW | LISH (Laparoscopic Ileocecal-Sparing Right Hemicolectomy), TRH(Traditional Laparoscopic Right Hemicolectomy) | Zhejiang University | Hepatic Flexure Colon Cancer, Proximal Transverse Colon Cancer | 05/26 | 05/31 | | |
| Recruiting | N/A | 100000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia | 01/38 | 01/38 | | |
| Recruiting | N/A | 40000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Alzheimer Disease, Familial Alzheimer Disease (FAD) | 01/38 | 01/38 | | |
NCT05409209: Carotid Plaque Length to Predict Cardiovascular Events |
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| Active, not recruiting | N/A | 3000 | RoW | | Changhai Hospital, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine | Coronary Artery Disease | 12/21 | 12/30 | | |
NCT05513664: Real-World Effectiveness of Osimertinib for Patients With Non-Small Cell Lung Cancer |
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| Not yet recruiting | N/A | 80 | RoW | Osimertinib | Shanghai JMT-Bio Inc., CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | Locally Advanced or Metastatic Non-Small Cell Lung Cancer, EGFR Exon20 Insertion Mutations | 06/23 | 08/23 | | |
Ellis, Peter |
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer |
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| Recruiting | 3 | 1016 | Europe, Canada, Japan, US, RoW | LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed | Eli Lilly and Company, Loxo Oncology, Inc. | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 10/26 | 10/29 | | |
| Withdrawn | 2 | 94 | NA | Durvalumab, MEDI4736, Imfinzi, Stereotactic Body Radiotherapy, Stereotactic Radiation, Stereotactic Radiation Therapy, Circulating Tumor DNA assay, AVENIO ctDNA surveillance assay, MRD Landmark assay | University of British Columbia, AstraZeneca, Ozmosis Research Inc. | Non Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Non-small Cell Lung Cancer Stage I, Lung Cancer, Lung Cancer Stage I, Lung Adenocarcinoma, Stage I, Lung Squamous Cell Carcinoma Stage I | 12/26 | 06/27 | | |
CCTG IND.238A, NCT03847649: A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity - Substudy B: For Continued Treatment (+/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies |
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| Recruiting | 2 | 60 | Canada | Durvalumab, Prednisone, Tremelimumab | Canadian Cancer Trials Group, AstraZeneca | Cancer | 04/30 | 04/31 | | |
Li, Ning |
NCT04351867: A Clinical Trial of Two Adjuvant Chemotherapy Regimens for Postoperative Gastric Cancer |
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| Not yet recruiting | 3 | 196 | RoW | docetaxel plus oxaliplatin and capecitabine, Three medicine combined, oxaliplatin plus capecitabine, Two medicine combined | LiNing | Stomach Neoplasms | 06/24 | 06/24 | | |
NCT06658353: Phase III Clinical Study of VC004 in Patients With Localized Advanced/ Metastatic Solid Tumors |
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| Not yet recruiting | 3 | 54 | RoW | VC004 Capsules | Jiangsu vcare pharmaceutical technology co., LTD | Locally Advanced Solid Tumor | 12/26 | 12/26 | | |
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer |
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| Recruiting | 3 | 1016 | Europe, Canada, Japan, US, RoW | LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed | Eli Lilly and Company, Loxo Oncology, Inc. | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 10/26 | 10/29 | | |
NCT05019794: Infigratinib in Subjects With GC or GEJ With FGFR2 Amplification or Other Solid Tumors With Other FGFR Alterations |
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| Recruiting | 2a | 80 | RoW | Infigratinib, BGJ398 | LianBio LLC | Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Solid Tumor | 12/22 | 12/23 | | |
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NCT03950271: SHR-1210 Combined With Trastuzumab , Oxaliplatin and Capecitabine for Neoadjuvant Therapy of Gastric Adenocarcinoma/Gastroesophageal Junction Adenocarcinoma |
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| Active, not recruiting | 2 | 25 | RoW | SHR-1210 Combined With Trastuzumab , Oxaliplatin and Capecitabine | Henan Cancer Hospital | Gastric Cancer | 01/24 | 12/26 | | |
NeoTOP, NCT06618014: Neoadjuvant Toripalimab Plus Docetaxel and Carboplatin in Patients With Localized TNBC |
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| Completed | 2 | 51 | RoW | Toripalimab, Docetaxel, Carboplatin | Sun Yat-sen University | Breast Cancer, Triple Negative Breast Cancer | 10/24 | 01/25 | | |
NCT04341857: PD-1 Monoclonal Antibody Combined With FLOT Regimen for Neoadjuvant Therapy of Gastric Adenocarcinoma |
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| Recruiting | 2 | 25 | RoW | PD-1 Monoclonal Antibody(Sintilimab) | Henan Cancer Hospital | Gastric and Esophagogastric Junction Adenocarcinoma | 05/22 | 07/22 | | |
NCT04423185: PLATFORM Study of Precision Medicine for Rare Tumors |
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| Not yet recruiting | 2 | 770 | NA | Almonertinib 110 MG, HS-10296, AMEILE, Dacomitinib 45 MG, Vizimpro, Alectinib 150 MG, Alecensa, Crizotinib 250 MG, Xalkori, Pyrotinib 160/80 MG, SHR-1258, Imatinib 400 MG, Gleevec, Niraparib 200/300 MG, Niraparix, Palbociclib 125mg, Ibrance, Vemurafenib 240 MG, Zelboraf, Sintilimab 100MG, Tyvyt, Atezolizumab 1680 MG, TECENTRIQ | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Rare Tumor | 07/22 | 07/23 | | |
NCT04062058: A Phase II Study of Total Neoadjuvant Therapy for Locally Advanced Gastric Cancer |
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| Recruiting | 2 | 82 | RoW | SIB-IMRT, S-1, SOX, Surgery | Jing Jin, M.D., Beijing Hope Run | Gastric Cancer, Neoadjuvant Therapy | 09/22 | 09/23 | | |
NCT04614740: The Phase I/Phase II Clinical Study of VC004 in Patients With Localized Advanced/Metastatic Solid Tumors |
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| Recruiting | 2 | 115 | RoW | VC004 | Jiangsu vcare pharmaceutical technology co., LTD | Locally Advanced Solid Tumor, Metastatic Solid Tumor | 01/24 | 06/24 | | |
NCT06322095: A Study of GH21 Combined With Previous Target Therapy or Immunotherapy in Patients With Advanced Solid Tumors |
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| Recruiting | 2 | 72 | RoW | PD-1, MET inhibitor, ALK inhibitor, BRAF Inhibito, EGFR Monoclonal antibody, GH21, MEK Inhibitor | Suzhou Genhouse Bio Co., Ltd. | Patients With Advanced Solid Tumor, Advanced Solid Tumor With Oncogenic Driver Mutations | 09/25 | 12/25 | | |
NCT06490068: Study of LTC004 Combine With Toripalimab in Patient With Solid Tumors Resistant to Immunotherapy |
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| Recruiting | 2 | 10 | RoW | LTC004+Toripalimab, LTC004 combine with Toripalimab | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Advanced Solid Tumor | 03/26 | 03/26 | | |
NCT05221658: A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCC |
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| Recruiting | 2 | 60 | RoW | HLX07+HLX10+ Cisplatin+5-FU, HLX07 | Shanghai Henlius Biotech | ESCC or Esophageal Adenosquamous Carcinoma | 06/24 | 08/25 | | |
| Not yet recruiting | 2 | 15 | RoW | ES014, ES014 for Injection | Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Elpiscience (Suzhou) Biopharma, Ltd. | Advanced Solid Tumor | 06/26 | 09/26 | | |
| Not yet recruiting | 2 | 42 | RoW | Neratinib tablets, Epilepsy | Convalife (Shanghai) Co., Ltd. | NSCLC | 12/24 | 12/25 | | |
NCT06798207: A Clinical Trial of TQB2102 for Injection in Gynecological Tumors With Recurrent/Metastatic Advanced |
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| Not yet recruiting | 2 | 90 | RoW | TQB2102 for injection | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Gynecological Tumors | 05/26 | 11/26 | | |
NCT04348643: Safety and Efficacy of CEA-Targeted CAR-T Therapy for Relapsed/Refractory CEA+ Cancer |
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| Recruiting | 1/2 | 40 | RoW | CEA CAR-T cells | Chongqing Precision Biotech Co., Ltd | Solid Tumor, Lung Cancer, Colorectal Cancer, Liver Cancer, Pancreatic Cancer, Gastric Cancer, Breast Cancer | 12/23 | 04/24 | | |
TranStar102, NCT04495296: A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors |
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| Recruiting | 1/2 | 320 | RoW | TST001, Oxaliplatin, Capecitabine, Paclitaxel, Gemcitabine, Cisplatin, Nivolumab | Suzhou Transcenta Therapeutics Co., Ltd., Bristol-Myers Squibb | Advanced Cancer | 02/25 | 05/25 | | |
NCT05260385: To Evaluate KC1036 in the Patients with Advanced Digestive System Tumors |
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| Recruiting | 1/2 | 133 | RoW | KC1036 | Beijing Konruns Pharmaceutical Co., Ltd. | Digestive System Tumors | 10/25 | 12/25 | | |
| Recruiting | 1/2 | 134 | US, RoW | PRO1160 | ProfoundBio US Co. | Renal Cell Carcinoma, Nasopharyngeal Carcinoma, Non Hodgkin Lymphoma | 11/26 | 03/27 | | |
NCT06612632: Immunotherapy Rechallenge in Patients with Solid Tumors in Clinical Trials |
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| Recruiting | 1/2 | 100 | RoW | research drug in combination with Toripalimab, Toripalimab | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Cancer | 06/26 | 06/28 | | |
CT041-ST-01, NCT04581473: Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection |
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| Recruiting | 1/2 | 192 | RoW | CT041 autologous CAR T-cell injection, CAR T-cell injection, Physician's Choice(Paclitaxel or Irinotecan or Apatinib or Anti-PD-1 antibody), Best support care(BSC) | CARsgen Therapeutics Co., Ltd., Peking University Cancer Hospital & Institute, Fudan University | Gastric Adenocarcinoma, Pancreatic Cancer, Gastroesophageal Junction Adenocarcinoma | 06/24 | 06/38 | | |
NCT05538195: Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors |
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| Recruiting | 1/2 | 60 | RoW | CEA-targeted CAR-T cells | Chongqing Precision Biotech Co., Ltd | Gastric Cancer, Colon Cancer, Rectal Cancer, Esophageal Cancer, Pancreatic Cancer | 12/24 | 06/25 | | |
| Recruiting | 1/2 | 404 | US, RoW | Rina-S, PRO1184, Rinatabart sesutecan, GEN1184, Carboplatin, Bevacizumab, Pembrolizumab | Genmab | Platinum-Resistant Ovarian Cancer, Platinum Sensitive Ovarian Cancer (PSOC), High Grade Epithelial Ovarian Cancer, High Grade Serous Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Cancer, Endometrial Cancer, Non-small Cell Lung Cancer, Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC), Mesothelioma, Breast Adenocarcinoma, Triple Negative Breast Cancer, Hormone Receptor-positive/Her2 Negative Breast Cancer | 04/26 | 10/26 | | |
NCT06088004: Phase Ⅰ/Ⅱ Clinical Study to Evaluate ABO2011 in Advanced Solid Tumors |
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| Recruiting | 1/2 | 218 | RoW | ABO2011 Injection, ABO2011, ABOD2011, Toripalimab | Suzhou Abogen Biosciences Co., Ltd., Abogen Biosciences (Shanghai) Co., Ltd | Solid Tumor, Adult | 12/26 | 12/27 | | |
NCT04615312: A Trail of CDK4 / 6 Inhibitor and MEK Inhibitor in the Treatment of Metastatic Digestive System Tumors |
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| Recruiting | 1 | 50 | RoW | a CDK4 / 6 inhibitor and a MEK inhibitor | Henan Cancer Hospital | Digestive System Tumors | 08/21 | 08/22 | | |
NCT04326296: The Safety and Tolerability of PD-L1 Monoclonal Antibody Plus Lenalidomide in The Treatment of Colorectal Cancer |
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| Not yet recruiting | 1 | 33 | RoW | PD-L1 Monoclonal Antibody Combined With Lenalidomide | LiNing | Colorectal Neoplasms | 09/22 | 03/23 | | |
NCT05881525: NY-ESO-1 TCR-T Cells for NY-ESO-1 Positive Subjects With Advanced Solid Tumors |
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| Recruiting | 1 | 18 | RoW | TC-N201 cells, IL-2, Fludarabine, Cyclophosphamide, Nab-paclitaxel | TCRCure Biopharma Ltd., Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Advanced Solid Tumors | 10/24 | 03/25 | | |
NCT06205082: A Phase I Clinical Trial to Evaluate LIT-00814 Tablets in Patients With Advanced Solid Tumor |
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| Enrolling by invitation | 1 | 81 | RoW | LIT-00814 | LittDD Medicines Ltd | Advanced Solid Tumor | 10/25 | 06/26 | | |
KSX01-R08-102, NCT06150365: Single Arm Clinical Study on the Safety and Efficacy of Personalized KSX01-TCRT in Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 12 | RoW | KSX01-TCRT cell therapy | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Refractory Solid Tumors, Relapsed Solid Tumors | 12/26 | 12/28 | | |
NCT05152212: Study of LVGN7409 (CD40 Agonist Antibody) in Locally Advanced, Metastatic or Recurrent/Refractory Malignancy |
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| Completed | 1 | 33 | RoW | LVGN7409 | Lyvgen Biopharma Holdings Limited | Cancer | 12/23 | 12/23 | | |
NCT06342336: HS-IT101 Injection in the Treatment of Advanced Solid Tumors |
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| Recruiting | 1 | 44 | RoW | HS-IT101 Injection, HS-IT101 | Qingdao Sino-Cell Biomedicine Co., Ltd., Cancer Institute and Hospital, Chinese Academy of Medical Sciences, The First Hospital of Jilin University, West China Hospital | Solid Tumor | 03/26 | 03/28 | | |
| Recruiting | 1 | 60 | RoW | BT02 monoclonal antibody injection | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Advanced Solid Tumor | 12/24 | 12/24 | | |
NCT05183243: GH21 Capsules for Advanced Solid Tumors: A Study on Safety and Early Results |
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| Recruiting | 1 | 68 | RoW | GH21 Capsule | Suzhou Genhouse Bio Co., Ltd. | Advanced Solid Tumor, Non-Small Cell Lung Cancer, Pancreatic Cancer, Colorectal Cancer, Head and Neck Neoplasm | 12/24 | 02/25 | | |
NCT06328673: A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors |
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| Recruiting | 1 | 160 | US, RoW | DM919, Pembrolizumab, Keytruda | D2M Biotherapeutics Inc. | Advanced Solid Tumor | 12/25 | 03/26 | | |