| Ramsey, Nick F |
| Recruiting | N/A | 2 | Europe | ECoG (electrocorticography) sensing, CortiCom-Utrecht assembly | UMC Utrecht, Johns Hopkins University | Locked-in Syndrome, Neuromuscular Diseases, Brainstem Stroke, Traumatic Brain Injury | 10/26 | 10/27 | | |
NCT02224469: First Study With a Brain Implant to Help Locked-in Patients Communicate at Home |
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| Completed | N/A | 3 | Europe | ECoG (electrocorticography) sensing, Activa PC + S | UMC Utrecht | Locked-In Syndrome | 02/24 | 02/24 | | |
| Pedersen, Susanne Juhl |
| Completed | N/A | 478 | Europe | Supportive care | Susanne Schmidt Pedersen, Odense University Hospital, Aarhus University Hospital, Aalborg University Hospital, University Hospital, Gentofte, Copenhagen, Zealand University Hospital | Implantable Defibrillator User, Distress | 12/22 | 05/23 | | |
eMYHeart, NCT04172974: EHealth Intervention to Manage Depression and Anxiety in Patients with Ischemic Heart Disease |
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| Completed | N/A | 198 | Europe | eHealth intervention, Usual Care | University of Southern Denmark, OPEN - Odense Patient data Explorative Network, The University of Southern Denmark, Odense, Denmark | Depression, Anxiety | 12/23 | 09/24 | | |
| Stella, Pieter |
NCT02661451: Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD) |
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| Active, not recruiting | N/A | 178 | Europe, Canada, US | SAPIEN 3 THV, Optimal Heart Failure Therapy | Cardiovascular Research Foundation, New York, Cardialysis BV, Avania | Aortic Valve Stenosis | 02/23 | 02/25 | | |
| Lier, Astrid van |
| Recruiting | N/A | 30 | Europe | | UMC Utrecht, Odense University Hospital | Cervical Cancer, Gynecologic Cancer | 10/25 | 10/27 | | |
| Aarnoutse, Erik J |
| Recruiting | N/A | 2 | Europe | ECoG (electrocorticography) sensing, CortiCom-Utrecht assembly | UMC Utrecht, Johns Hopkins University | Locked-in Syndrome, Neuromuscular Diseases, Brainstem Stroke, Traumatic Brain Injury | 10/26 | 10/27 | | |
| Boelens, Jaap Jan |
BRIDGE, NCT05787574: A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition |
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| Recruiting | 2 | 39 | US | Emapalumab, Fludarabine and Dexamethasone, Stem Cell Transplant | Memorial Sloan Kettering Cancer Center, Sobi, Inc. | Primary Immune Regulatory Disorder, Autoimmune Lymphoproliferative, Immune System Diseases | 03/27 | 03/27 | | |
NCT04990323: US Study of ECT-001-CB in Pediatric and Young Adult Patients With High-Risk Myeloid Malignancies |
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| Recruiting | 1/2 | 12 | US | ECT-001-CB (UM171-Expanded Cord Blood Transplant), Conditioning Regimen (Preferred): clofarabine:30 mg/m2/day IV x 4 days, fludarabine:10 mg/m2/day IV x 4 days, busulfan: daily for 4 days with cumm Bu target = 90mg h/L, Conditioning Regimen (Alternative): MIDI: fludarabine: 30 mg/m2/day IV x 5 days, cyclophosphamide: 50 mg/kg IV , thiotepa: 5 mg/kg/day IV x 2 days , TBI: 400 cGy, GVHD Prophylaxis: Tacrolimus/MMF | ExCellThera inc., Memorial Sloan Kettering Cancer Center | High Risk Myeloid Malignancies, Cord Blood Transplant | 06/26 | 06/26 | | |
NCT04443907: Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD) |
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| Active, not recruiting | 1 | 4 | US | OTQ923, Adult Part A, Children 2-17 years old - Part B | Novartis Pharmaceuticals | Sickle Cell Disease | 01/25 | 01/25 | | |
NCT05569512: Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation for AML |
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| Terminated | 1 | 1 | US | Uproleselan, Fludarabine, Fludara, Clofarabine, Clolar, Busulfan, Busulfex, Myleran | Malika Kapadia, GlycoMimetics Incorporated | Acute Myeloid Leukemia, Pediatric Cancer | 10/23 | 12/23 | | |
| Vulpen, Marco van |
| Completed | N/A | 80 | Europe | | Erasmus Medical Center, HollandPTC, Amsterdam University Medical Center, Leiden University Medical Center, Delft University of Technology, Medical Center Haaglanden | Astrocytoma, Grade II, Astrocytoma, Grade III, Oligodendroglioma, Oligodendroglioma, Anaplastic | 06/24 | 06/24 | | |
NCT02839863: Utrecht Cohort for Multiple Breast Cancer Intervention Studies and Long-term Evaluation - The UMBRELLA Cohort |
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| Recruiting | N/A | 10000 | Europe | | UMC Utrecht | Breast Cancer | 10/53 | 10/53 | | |
| Meine, Mathias |
| Recruiting | N/A | 130 | Europe | CARTBox | UMC Utrecht, CART-Tech B.V., ZonMw: The Netherlands Organisation for Health Research and Development, Health Holland | Heart Failure | 04/23 | 02/25 | | |
| Recruiting | N/A | 330 | Europe | Pre-implantation planning, ECGI mapping, Post-implantation assessment | EP Solutions SA | Heart Failure With Reduced Ejection Fraction | 09/25 | 06/26 | | |
| Vansteensel, Mariska J |
| Recruiting | N/A | 2 | Europe | ECoG (electrocorticography) sensing, CortiCom-Utrecht assembly | UMC Utrecht, Johns Hopkins University | Locked-in Syndrome, Neuromuscular Diseases, Brainstem Stroke, Traumatic Brain Injury | 10/26 | 10/27 | | |
| Checa, Cesar Magro |
| Recruiting | 2 | 60 | Europe | Filgotinib | UMC Utrecht, Alfasigma S.p.A., ReumaNederland, Autoimmune Research and Collaboration Hub | Behcet's Disease, Idiopathic Inflammatory Myopathies, IgG4-related Disease | 12/26 | 12/26 | | |
