Yang, Yi |
NCT04739592: A Study of Alendronate Sodium Vitamin D3 Tablets on Knee Osteoarthritis |
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| Recruiting | 4 | 60 | RoW | alendronate sodium vitamin D3 tablets, Placebo | Peking Union Medical College Hospital, CSPC Ouyi Pharmaceutical Co., Ltd. | Knee Osteoarthritis | 07/23 | 07/24 | | |
NCT06645522: Safety and Efficacy of Edaravone Dexborneol for Acute Ischemic Stroke |
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| Not yet recruiting | 4 | 1200 | RoW | Edaravone dexborneol, Placebo | Yi Yang | Acute Ischemic Stroke | 10/26 | 01/27 | | |
| Completed | 3 | 1412 | RoW | Injection of recombinant human tissue plasminogen kinase derivatives, Reteplase, brand name: Ruitongli, r-PA, Recombinant human tissue plasminogen activator, Alteplase, brand name: Actilyse, rt-PA | Angde Biotech Pharmaceutical Co., Ltd., Beijing Tiantan Hospital | Acute Ischemic Stroke | 06/23 | 06/23 | | |
NCT05745259: Thrombolysis Treated With TNK-tPA in Acute Ischemic Stroke Patients (3T Stroke-Ⅲ) |
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| Recruiting | 3 | 1630 | RoW | Alteplase, rt-PA, Tenecteplase, TNK-tPA | Beijing Tiantan Hospital, Jiangsu FENG HUA Biotech Pharmaceutical Co., Ltd, The Place Pharmaceutical(Jiangsu) Co., Ltd | Acute Ischemic Stroke | 11/23 | 03/24 | | |
NCT06338995: A Study of Lebrikizumab (LY3650150) in Adult Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) |
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| Recruiting | 3 | 510 | Europe, Canada, Japan, US, RoW | LY3650150, Placebo, Standard therapy for INCS | Eli Lilly and Company | Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) | 10/26 | 02/27 | | |
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer |
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| Recruiting | 3 | 1016 | Europe, Canada, Japan, US, RoW | LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed | Eli Lilly and Company, Loxo Oncology, Inc. | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 10/26 | 10/29 | | |
| Recruiting | 3 | 170 | Europe, Canada, Japan, US, RoW | Selpercatinib, LY3527723, LOXO-292, Placebo | Loxo Oncology, Inc., Eli Lilly and Company | Carcinoma, Non-Small-Cell Lung | 05/27 | 08/32 | | |
NCT04898322: SY-005 (Recombinant Human Annexin A5)in Patients With Sepsis |
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| Recruiting | 2a | 96 | RoW | SY-005, Placebo | Suzhou Yabao Pharmaceutical R&D Co., Ltd. | Sepsis | 07/23 | 07/23 | | |
NCT05865496: A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps |
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| Active, not recruiting | 2 | 90 | RoW | 611, Placebo | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | Sinusitis, Nasal Polyps, Polyps | 05/24 | 07/24 | | |
NCT06664996: Sintilimab Combined SBRT As Neoadjuvant Therapy for Resectable HCC with PVTT |
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| Recruiting | 2 | 33 | RoW | stereotactic body radiation therapy (SBRT), Sintilimab (approved) | West China Hospital | Hepatocellular Carcinoma (HCC) | 10/25 | 10/26 | | |
NCT05686642: Efficacy and Safety of LT3001 on Treating the Acute Ischemic Stroke |
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| Recruiting | 2 | 300 | RoW | LT3001 Drug:high dose, Placebo, LT3001 Drug:low dose | Shanghai Pharmaceuticals Holding Co., Ltd | Acute Ischemic Stroke | 04/25 | 07/25 | | |
NCT06089278: A Clinical Study of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps. |
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| Recruiting | 2 | 160 | RoW | 300mg of TQH2722 injection, 600mg of TQH2722 injection, TQH2722 injection matching placebo | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Sinusitis | 05/25 | 05/25 | | |
NCT06038916: To Evaluate the Safety and Initial Efficacy of STSA-1002 Injection in Patients with Acute Respiratory Distress Syndrome |
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| Recruiting | 1/2 | 60 | RoW | STSA-1002 Injection Placebo, STSA-1002 Injection | Staidson (Beijing) Biopharmaceuticals Co., Ltd | Acute Respiratory Distress Syndrome | 08/25 | 09/26 | | |
NCT05590572: A Study of Sulfatinib on Relapsed or Refractory Drug Resistant Osteosarcoma |
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| Not yet recruiting | 1/2 | 148 | RoW | Sulfatinib, Etoposide, Isophosphamide | Second Affiliated Hospital, School of Medicine, Zhejiang University, Chonnam National University, Peking University People's Hospital, Qilu Hospital of Shandong University, Ruijin Hospital, Shanghai Jiao Tong University Affiliated Sixth People's Hospital | Osteosarcoma | 12/26 | 12/27 | | |
NCT04536337: A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects |
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| Recruiting | 1 | 336 | Europe, RoW | ALG-000184, Placebo, Entecavir | Aligos Therapeutics | Chronic Hepatitis B | 11/23 | 06/24 | | |
NCT04980625: Safety and Efficacy of Remote Ischemic Conditioning Combined With Intravenous Thrombolysis for Acute Ischemic Stroke |
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| Completed | N/A | 558 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Acute Ischemic Stroke | 05/23 | 05/23 | | |
CASCAS, NCT05028855: Cerebral Autoregulation in Patients With Symptomatic Cerebral Atherosclerotic Stenosis |
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| Recruiting | N/A | 850 | RoW | Cerebral autoregulation assessment | Yi Yang, Shenzhen Second People's Hospital, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, The First Affiliated Hospital with Nanjing Medical University, The First Affiliated Hospital of University of South China, Eighth Affiliated Hospital, Sun Yat-sen University, The First Affiliated Hospital of Hebei North University, Qilu Hospital of Shandong University, The Affiliated Hospital of Qingdao University, The Affiliated Hospital of Yanbian University | Cerebrovascular Stroke, Cerebral Artery Stenosis | 12/25 | 08/26 | | |
| Recruiting | N/A | 3000 | RoW | Treatment following current guidelines | Yi Yang, Jiujiang No.1 People's Hospital, Dezhou People's Hospital, The Affiliated Hospital of Yanbian University, First Affilated Hospital of Jiamusi University, Xuchang Central Hospital, Inner Mongolia People's Hospital, Shaoxing People's Hospital, Chinese PLA General Hospital, General Hospital of Ningxia Medical University, General Hospital of Shenyang Military Region, Siping Central People's Hospital, The First Affilated Hospital of the Medical College, Shihezi University, Daqing Oilfieled General Hospital, Heilongjiang Provicial Hospital, The First Affiliated Hospital of Soochow University, Luoyang Central Hospital Affilated to Zhengzhou University, Wuzhou Red Cross Hospital, Cangzhou Central Hospital, Binzhou Medical University, Affilated Hospital of Inner Mongolia University for the Nationalities, Fudan University Pudong Medical Center | Ischemic Stroke | 12/24 | 07/25 | | |
SRICDCA-IVT, NCT05550103: Effect of Serial Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation in Patients With Intravenous Thrombolysis |
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| Recruiting | N/A | 60 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning, Standard medical treatment | Yi Yang | Acute Ischemic Stroke | 02/23 | 05/23 | | |
NCT05599009: Remote Ischemic Conditioning and Dynamic Cerebral Autoregulation in Patients With Intracranial and Extracranial Arteriosclerosis |
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| Recruiting | N/A | 140 | RoW | remote ischemic conditioning, sham remote ischemic conditioning | The First Hospital of Jilin University | Carotid Stenosis, Ischemic Stroke | 02/23 | 02/23 | | |
ESCAPE-SVD, NCT05225948: Effects of Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation, Blood Pressure and Heart Rate Variability in Patients With Cerebral Small Vessel Disease |
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| Recruiting | N/A | 100 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Cerebral Small Vessel Diseases | 07/25 | 10/25 | | |
NCT04541758: Comparing the Efficacy of Conservative Treatment With Minimally Invasive Surgery in the Treatment of Rib Fractures |
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| Not yet recruiting | N/A | 238 | NA | surgical treatment, Conservative treatment | Shanghai 6th People's Hospital | Chest Trauma, Rib Fractures, Surgery--Complications | 06/23 | 06/24 | | |
SERIC-EVT, NCT04977869: Safety and Efficacy Study of Remote Ischemic Conditioning Combined With Endovascular Thrombectomy for Acute Ischemic Stroke Due to Large Vessel Occlusion of Anterior Circulation |
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| Completed | N/A | 498 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Acute Ischemic Stroke | 09/24 | 09/24 | | |
NCT05598658: Effect of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients After Intravenous Thrombolysis (RICCH-IVT) |
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| Completed | N/A | 100 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Remote Ischemic Conditioning | 01/24 | 04/24 | | |
NCT05970653: Effect of RIC on Cerebral Autoregulation in Patients Undergoing Cerebrovascular Stent Implantation |
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| Recruiting | N/A | 104 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Remote Ischemic Conditioning | 05/24 | 08/24 | | |
NCT05843240: Effects of Repetitive Transcranial Magnetic Stimulation on Cerebral Autoregulation in Patients With Acute Ischemic Stroke |
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| Recruiting | N/A | 128 | RoW | Repetitive transcranial magnetic stimulation, Sham repetitive transcranial magnetic stimulation | Yi Yang | Transcranial Magnetic Stimulation | 03/24 | 06/24 | | |
NCT05914623: Effects of High-frequency Repetitive Transcranial Magnetic Stimulation on Cerebral Autoregulation in Patients With Cerebral Small Vessel Disease |
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| Recruiting | N/A | 80 | RoW | Repetitive transcranial magnetic stimulation, Sham repetitive transcranial magnetic stimulation | Yi Yang | Transcranial Magnetic Stimulation | 04/24 | 07/24 | | |
SERIC-EH, NCT03945305: Safety and Efficacy of Remote Ischemic Conditioning Treatment for Community-based Essential Hypertension |
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| Recruiting | N/A | 500 | RoW | Patients are treated with previous antihypertensive treatment plus remote ischemic conditioning., Previous antihypertensive treatment | Yi Yang | Essential Hypertension | 03/24 | 04/24 | | |
NCT05743101: Safety and Efficacy Study of Levofloxacin Combined With Endovascular Thrombectomy for Acute Ischemic Stroke |
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| Not yet recruiting | N/A | 80 | NA | Levofloxacin, Endovascular thrombectomy, Levofloxacin simulant | Yi Yang | Acute Ischemic Stroke | 04/26 | 07/26 | | |
NCT05910242: Efficacy and Safety of Remote Ischemic Conditioning in the Treatment of Essential Hypertension (RICBP-EH) |
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| Recruiting | N/A | 102 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Essential Hypertension | 03/24 | 03/24 | | |
NCT06140888: Effect of Ginkgo Biloba Extract on Cognitive Function in Acute Ischemic Stroke |
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| Not yet recruiting | N/A | 356 | NA | Ginkgo Biloba Extract | Yi Yang | Acute Ischemic Stroke | 10/26 | 04/27 | | |
NCT06137300: Safety and Efficacy of Urinary Kallidinogenase for Large Artery Atherosclerosis Acute Ischemic Stroke |
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| Not yet recruiting | N/A | 986 | RoW | Urinary kallidinogenase for injection, Guideline-prescribed medical therapy | Yi Yang | Acute Ischemic Stroke | 06/26 | 12/27 | | |
NCT05845905: Effects of Remote Ischemic Conditioning on Blood Pressure in Older Patients With Hypertension |
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| Recruiting | N/A | 158 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Essential Hypertension | 12/24 | 12/24 | | |
NCT05915923: Effect of Transcranial Magnetic Stimulation on Dynamic Cerebral Autoregulation in Healthy Adults |
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| Recruiting | N/A | 90 | RoW | 1 Hz Repetitive transcranial magnetic stimulation, 10 Hz Repetitive transcranial magnetic stimulation, Sham Repetitive transcranial magnetic stimulation | Yi Yang | Transcranial Magnetic Stimulation | 04/24 | 04/24 | | |
NCT05741905: Safety and Efficacy of Levofloxacin Combined With Intravenous Thrombolysis for Acute Ischemic Stroke |
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| Recruiting | N/A | 100 | RoW | Levofloxacin, Intravenous Thrombolysis, Levofloxacin simulant | Yi Yang | Acute Ischemic Stroke | 12/24 | 12/24 | | |
NCT06423547: Risk Warning Model of Postoperative Delirium and Long-term Cognitive Dysfunction in Elderly Patients |
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| Not yet recruiting | N/A | 10000 | NA | no intervention | Xuanwu Hospital, Beijing, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences | Postoperative Delirium, Postoperative Neurocognitive Disorder, Surgery | 12/27 | 12/27 | | |
NCT05799326: Safety and Efficacy of Levofloxacin for Acute Ischemic Stroke |
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| Recruiting | N/A | 100 | RoW | Levofloxacin, Levofloxacin simulant | Yi Yang | Acute Ischemic Stroke | 12/24 | 12/24 | | |
NCT04980651: Safety and Efficacy of Remote Ischemic Conditioning for Acute Ischemic Stroke |
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| Recruiting | N/A | 2210 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Acute Ischemic Stroke | 07/25 | 10/25 | | |
SERIC-sICH, NCT03484936: Safety and Efficacy of Remote Ischemic Conditioning in Patients With Spontaneous Intracerebral Hemorrhage |
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| Not yet recruiting | N/A | 530 | RoW | Remote ischemic conditioning, RIC, Sham remote ischemic conditioning, Sham RIC | Yi Yang | Intracranial Hemorrhages | 09/26 | 06/27 | | |
| Not yet recruiting | N/A | 912 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Acute Ischemic Stroke | 09/26 | 09/26 | | |
NCT06595342: A Prospective Cohort of Patients With Cervical/Intracranial Arteries Stenosis in China |
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| Not yet recruiting | N/A | 60000 | RoW | No intervention | The First Hospital of Jilin University | Cervical Artery Stenosis, Intracranial Artery Stenosis | 06/26 | 06/30 | | |
| Not yet recruiting | N/A | 342 | RoW | Osimertinib, Alectinib, TORIPALIMAB INJECTION (JS001 ) combine with chemotherapy | Guangdong Association of Clinical Trials, Nanjing Geneseeq Technology Inc. | Non-Small Cell Lung Cancer | 01/29 | 01/32 | | |
RICCH-IS, NCT05915832: Effects of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients With Ischemic Stroke |
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| Recruiting | N/A | 120 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Acute Ischemic Stroke | 12/24 | 03/25 | | |
SERIC-HS, NCT06702644: Safety and Efficacy of Remote Ischemic Conditioning in Patients with Chronic Internal Carotid Artery Occlusion Receiving Hybird Surgery: a Pilot, Randomized Controlled Trial |
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| Not yet recruiting | N/A | 60 | NA | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Carotid Artery Occlusion | 11/26 | 03/27 | | |
SERIC-CASCEA, NCT06033963: Safety and Efficacy of Remote Ischemic Conditioning in Patients With Carotid Artery Stenosis Receiving Carotid EndArterectomy |
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| Recruiting | N/A | 100 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Carotid Artery Stenosis | 12/24 | 03/25 | | |
NCT05609110: Safety and Efficacy of Remote Ischemic Conditioning for Spontaneous Intracerebral Hemorrhage |
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| Recruiting | N/A | 2000 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Yi Yang | Intracranial Hemorrhages | 01/25 | 05/25 | | |
CRISTINA, NCT05028868: Clinical Research of Intravenous Thrombolysis for Ischemic Stroke in Northeast of China |
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| Recruiting | N/A | 500 | RoW | | Yi Yang | Ischemic Stroke, Thrombosis | 02/25 | 01/26 | | |
NCT06740500: Effect of Bifidobacterium Animalis Subsp. Lactis Bi66 Supplementation on Gut Function in Healthy Adults |
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| Not yet recruiting | N/A | 120 | RoW | Probiotic, Bifidobacterium animalis subsp. lactis Bi66, Placebo | Huazhong University of Science and Technology | Healthy Adult | 06/25 | 08/25 | | |
NCT05798013: Effectiveness of Digital Health Management on Patients With Head and Neck Vascular Stenosis |
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| Not yet recruiting | N/A | 102072 | RoW | Digital health management | Yi Yang | Head and Neck Vascular Stenosis | 10/27 | 10/28 | | |
NCT06045156: Early Tirofiban Administration After Intravenous Thrombolysis in Acute Ischemic Stroke |
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| Recruiting | N/A | 1084 | RoW | Tirofiban, Tirofiban simulant | The First Hospital of Jilin University | Acute Ischemic Stroke | 01/26 | 12/26 | | |
NCT05881226: Application of Biomarkers in Neurological Diseases |
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| Recruiting | N/A | 3000 | RoW | | Yi Yang | Biomarkers | 12/30 | 12/31 | | |