Tropical Diseases Research Centre
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 3 Trials 
9 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Moss, William J
NCT04009343: Pharmacokinetics and Pharmacodynamics of the Gametocytocidal and Post-treatment Chemoprotective Effects of Antimalarials

Active, not recruiting
2/3
182
RoW
Artemether-lumefantrine, Coartem®, Dihydroartemisinin-piperaquine, D-Artepp®
Johns Hopkins Bloomberg School of Public Health, Tropical Diseases Research Centre
Uncomplicated Falciparum Malaria
08/20
03/25
Manyando, Christine
CALINA, NCT04300309: Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria

Terminated
2/3
28
RoW
artemether:lumefantrine (2.5 mg:30 mg)
Novartis Pharmaceuticals, European and Developing Countries Clinical Trials Partnership (EDCTP), Medicines for Malaria Venture (MMV), Switzerland, Groupe de Recherche Action en Santé (GRAS), Ouagadougou, Burkina Faso, Institut de Recherche en sciences de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Burkina Faso
Plasmodium Falciparum Malaria
07/23
05/24
NCT05974267: Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

Completed
2
192
RoW
M5717 60 mg, Pyronaridine, Pyronaridine tetraphosphate, Atovaquone-Proguanil, M5717 200 mg, M5717 660mg
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Malaria Infection
12/24
12/24
TANUMIHARDJO, Sherry A
NCT05319548: Plant Pigments for Human Health: Impact of Lycopene and Anthocyanins on Bioefficacy of Provitamin A Carotenoids From Carrots

Completed
N/A
12
US
Purple-Red Carrot Juice, Red Carrot Juice, Purple Carrot Juice
University of Wisconsin, Madison
Healthy
05/23
05/23
NCT06438562: Evaluation of Vitamin A Absorption From Fortified Bouillon

Recruiting
N/A
60
US, RoW
Unfortified bouillon plus vitamin A in oil, Bouillon fortified with vitamin A #1 plus unfortified oil, Bouillon fortified with vitamin A #2 plus unfortified oil
University of Wisconsin, Madison, Particles for Humanity, PBC, Tropical Diseases Research Centre, Zambia
Healthy Volunteers, Vitamin A
09/25
12/25
RID_VAB, NCT06759493: Validation and Simplification of the Retinol Isotope Dilution Technique in Burkinabe Schoolchildren

Recruiting
N/A
158
RoW
Retinol isotope dilution technique, Modified relative dose response (MRDR) test, 3,4-didehydroretinyl acetate in oil
Institut de Recherche en Sciences de la Sante, Burkina Faso, International Atomic Energy Agency (IAEA)
Vitamin A Deficiency, Inflammation
01/25
06/25
Chileshe, Justin
SBT4EE, NCT04109352: Labelled Carbon Sucrose Breath Test (13C-SBT) as a Marker of Environmental Enteropathy

Recruiting
N/A
600
Europe, RoW
University of Virginia, International Atomic Energy Agency, Flinders University, International Centre for Diarrhoeal Disease Research, Bangladesh, St. John's Research Institute, The University of The West Indies, Mmust Masinde Muliro University of Science and Technology, Asociacion Benefica Prisma, Scottish Universities Environmental Research Centre, University of Michigan, Tropical Diseases Research Centre, Zambia, Gastroenterology Services, Ltd.
Glucose-Galactose Malabsorption, Enteropathy, Malnutrition, Child, Intestinal Permeability, Linear Growth Failure
07/22
12/22
NCT06438562: Evaluation of Vitamin A Absorption From Fortified Bouillon

Recruiting
N/A
60
US, RoW
Unfortified bouillon plus vitamin A in oil, Bouillon fortified with vitamin A #1 plus unfortified oil, Bouillon fortified with vitamin A #2 plus unfortified oil
University of Wisconsin, Madison, Particles for Humanity, PBC, Tropical Diseases Research Centre, Zambia
Healthy Volunteers, Vitamin A
09/25
12/25
Kabuya, Jean-Bertin
PLATFORM, NCT05711485: Platelet-Directed Whole Blood Transfusion Strategy for Malaria

Recruiting
N/A
132
US, RoW
Whole blood transfusion
Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Tropical Diseases Research Centre, University of California, San Francisco, University of Maryland
Severe Malaria, Thrombocytopenia
04/26
04/27

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