| Zhang, Yan |
NCT05291650: Ultrasound-guided Injection of Glucocorticoid Into Infrapatellar Fat Pad in Patients With Knee Osteoarthritis |
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| Completed | 4 | 60 | RoW | Glucocorticoids, Saline, Hyaluronic acid | Zhujiang Hospital | Osteoarthritis, Knee | 09/23 | 12/23 | | |
NCT04790305: Effect of Huaier Granule on Adjuvant Treatment for High-risk Early-stage Triple-negative Breast Cancer |
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| Recruiting | 4 | 1072 | RoW | Huaier Granule, Z20000109（NMPA Approval Number） | Fudan University, LinkDoc Technology (Beijing) Co. Ltd., Huazhong University of Science and Technology | Carcinoma Breast, Triple-negative Breast Cancer, Invasive Ductal Carcinoma, Breast | 12/27 | 07/28 | | |
ETER701, NCT04234607: A Study of TQB2450 or Placebo Combined With Anlotinib, Etoposide and Carboplatin Versus Etoposide and Carboplatin in Subjects With Extensive Small Cell Lung Cancer |
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| Not yet recruiting | 3 | 738 | RoW | TQB2450, Anlotinib, Etoposide, Carboplatin, TQB2450（blank）, Anlotinib（blank) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Extensive Small Cell Lung Cancer | 12/22 | 12/22 | | |
| Active, not recruiting | 3 | 453 | Europe, US, RoW | MRTX849, adagrasib, KRAZATI, Docetaxel, Taxotere | Mirati Therapeutics Inc., Mirati Therapeutics, Inc. | Metastatic Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer | 12/23 | 12/24 | | |
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NCT05181137 / 2021-001940-86: A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis |
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| Recruiting | 3 | 368 | Europe, US, RoW | SHR0302, Placebo | Reistone Biopharma Company Limited, Reistone Biopharma Company Limited | Ulcerative Colitis | 10/24 | 03/25 | | |
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer |
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| Recruiting | 3 | 1016 | Europe, Canada, Japan, US, RoW | LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed | Eli Lilly and Company, Loxo Oncology, Inc. | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 10/26 | 10/29 | | |
NCT02159820: Lower Dose Decitabine (DAC)-Primed TC (Carboplatin-Paclitaxel) Regimen in Ovary Cancer |
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| Recruiting | 2/3 | 500 | RoW | Decitabine (DTC Arm), Paclitaxel and Carboplatin (TC Arm) | Chinese PLA General Hospital | Primary Malignant Neoplasm of Ovary, FIGO Stages II to IV | 06/24 | 06/24 | | |
EVEREST, NCT06531161: EleVation carE: a Randomized Controlled Trial on the Prevention of Acute Mountain Sickness With Suxiao Jiuxin Pill |
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| Not yet recruiting | 2/3 | 168 | NA | Suxiao Jiuxin Pill, Placebo | Peking University First Hospital, Tibet Autonomous Region Hospital of Traditional Tibetan Medicine | Acute Mountain Sickness | 09/24 | 09/25 | | |
NCT03989336: A Study of the Pan-immunotherapy in Patients With Relapsed/Refractory Ovarian Cancer |
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| Completed | 2 | 84 | RoW | Manganese Chloride, nab-paclitaxel, Paclitaxel For Injection (Albumin Bound), Platinum chemotherapy, Sintilimab, anti-PD-1 antibody; PD-1 inhibitor | Chinese PLA General Hospital | Ovarian Cancer | 05/22 | 12/23 | | |
NCT03250962: SHR-1210 Alone or in Combination With Decitabine in Relapsed or Refractory Hodgkin Lymphoma |
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| Recruiting | 2 | 280 | RoW | SHR-1210, Decitabine | Chinese PLA General Hospital | Hodgkin Lymphoma | 07/22 | 03/25 | | |
LEAD, NCT05092412: Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC |
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| Active, not recruiting | 2 | 30 | RoW | Low-dose radiotherapy, Durvalumab, Etoposide, and cisplatin/carboplatin | You Lu, AstraZeneca | Lung Cancer, Extensive-stage Small-cell Lung Cancer, Durvalumab | 02/23 | 06/25 | | |
| Recruiting | 2 | 30 | RoW | Polatuzumab Vedotin, Rituximab, Lenalidomide | Yan Zhang, MD, Peking University Third Hospital, Peking University First Hospital, Chinese PLA General Hospital | Diffuse Large B Cell Lymphoma | 10/25 | 10/27 | | |
PUMCH-NHL-013, NCT05390749: Sequential Treatment With RO-MTX After Pomalidomide, Orelabrutinib, Rituximab (POR) in Newly-diagnosed PCNSL |
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| Recruiting | 2 | 50 | RoW | Orelabrutinib, Pomalidomide, Rituximab, Methotrexate | Peking Union Medical College Hospital, Beijing Tiantan Hospital, Sanbo Brain Hospital Capital Medical University | Primary Central Nervous System Lymphoma | 04/24 | 04/26 | | |
NCT06632262: A Phase 2 Clinical Study of ABSK061 and ABSK043 |
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| Not yet recruiting | 2 | 202 | RoW | ABSK061 + ABSK043, ABSK061+ABSK043 in combination with CAPOX | Abbisko Therapeutics Co, Ltd | HER2-Gastric/Gastroesophageal Junction Cancer, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Solid Tumors | 11/29 | 06/30 | | |
FOCUS-C, NCT05334277: Furmonertinib Monotherapy and Combination Therapy in Advanced EGFR Mutant NSCLC With Uncleared ctDNA |
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| Recruiting | 2 | 280 | RoW | Furmonertinib, AST2818, Furmonertinib/Pemetrexed/Carboplatin, Furmonertinib/Pemetrexed/Carboplatin/Bevacizumab | Sun Yat-sen University, Allist Pharmaceuticals, Inc., GeneCast Biotechnology Co., Ltd. | Non-small Cell Lung Cancer | 02/25 | 02/28 | | |
IMM01-04, NCT05833984: Safety and Efficacy of IMM01 Plus Tislelizumab in Patients With Advanced Solid Tumors and Lymphomas |
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| Recruiting | 1b/2 | 309 | RoW | IMM01, SIRPα Fc, Tislelizumab | ImmuneOnco Biopharmaceuticals (Shanghai) Inc. | Solid Tumor, Classic Hodgkin Lymphoma | 02/24 | 11/24 | | |
NCT03989310: An Open-label, Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic Pancreatic Cancer |
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| Recruiting | 1/2 | 50 | RoW | Manganese Chloride, nab-paclitaxel, Paclitaxel For Injection (Albumin Bound), Gemcitabine, anti-PD-1 antibody, Anti-PD-1 monoclonal antibody; PD-1 inhibitor | Chinese PLA General Hospital | Pancreatic Cancer | 05/21 | 03/22 | | |
NCT04588324: Study of SHR2150 (TLR7 Agonist) in Combination With Chemotherapy Plus PD-1 or CD47 Antibody in Subjects With Unresectable/ Metastatic Solid Tumors |
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| Recruiting | 1/2 | 50 | RoW | SHR2150, Anti-Cancer Agent | Chinese PLA General Hospital | Solid Tumor | 11/21 | 11/22 | | |
NCT04873440: An Open-label, Phase I/II Study of Manganese Plus Radiotherapy in Patients With Metastatic Solid Tumors or Lymphoma |
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| Recruiting | 1/2 | 10 | RoW | Manganese Chloride, Mn2+, Radiotherapy, Chemo-immunotherapy | Chinese PLA General Hospital | Solid Tumor, Lymphoma | 05/22 | 05/23 | | |
REMLA, NCT04120350: R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL：a Multicenter Phase Ib/II Stuty |
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| Recruiting | 1/2 | 47 | RoW | Methotrexate, Rituximab, Lenalidomide | Peking Union Medical College Hospital, Beijing Tiantan Hospital, Xuanwu Hospital, Beijing, Peking University Third Hospital, Beijing Hospital, Peking University First Hospital, Chinese PLA General Hospital | Primary Central Nervous System Lymphoma | 08/22 | 08/24 | | |
NCT05867771: A Study of PM1022 in Patients With Advanced Tumors |
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| Recruiting | 1/2 | 200 | RoW | PM1022 | Biotheus Inc. | Advanced Tumors | 04/24 | 04/25 | | |
NCT05416775: Phase Ib/II Study of SHR-8068 Injection in the Treatment of Advanced Non-small Cell Lung Cancer |
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| Recruiting | 1/2 | 168 | RoW | SHR-8068；Adebrelimab, SHR-8068；adebrelimab and platinum-based chemotherapy, Adebrelimab；platinum-based chemotherapy | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Non-small Cell Lung Cancer | 06/26 | 06/26 | | |
NCT05245916: IBI397 or Combination Therapies in Patients With Advanced Malignancies |
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| Withdrawn | 1a/1b | 30 | RoW | IBI397, IBI397+Sintilimab, IBI397+Rituximab | Innovent Biologics (Suzhou) Co. Ltd. | Advanced Malignancies | 08/23 | 08/23 | | |
NCT06271928: A Multicenter Clinical Study of Yijing Keli in the Treatment of Ovarian Aging |
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| Recruiting | 1 | 100 | RoW | Yijing Keli | Tongji Hospital | Ovarian Aging | 01/24 | 01/25 | | |
NCT04487093: Clinical Study of Neoantigen Vaccine Combined With Targeted Drugs in the Treatment of Non-small Cell Lung Cancer |
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| Recruiting | 1 | 20 | RoW | neoantigen vaccine + EGFR-TKI, neoantigen vaccine + anti-angioge | First Hospital of Shijiazhuang City, Tianjin Hengjia Biotechnology Development co., LTD | Non Small Cell Lung Cancer | 05/22 | 12/22 | | |
NCT06256783: A Clinical Study of Baozhu Keli in the Treatment of Ovarian Aging |
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| Recruiting | 1 | 100 | RoW | Baozhu Keli | Tongji Hospital | Ovarian Aging | 01/24 | 01/25 | | |
| Recruiting | 1 | 132 | Japan, RoW | SHR-A2009 | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Solid Tumors | 12/23 | 12/24 | | |
NCT05508334: A Study to Assess the Safety and Tolerability of RC88 for Patients with Advanced Solid Tumours |
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| Active, not recruiting | 1 | 81 | RoW | RC88, The injectable RC88 | RemeGen Co., Ltd. | Advanced Solid Tumours | 06/25 | 12/25 | | |
| Recruiting | 1 | 156 | US, RoW | CS5001 | CStone Pharmaceuticals | Advanced Solid Tumor, Advanced Lymphoma | 03/25 | 06/25 | | |
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NCT06384352: A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 155 | Canada, US, RoW | YL211 | MediLink Therapeutics (Suzhou) Co., Ltd., Hoffmann-La Roche | Advanced Solid Tumors | 04/27 | 04/29 | | |
| Completed | N/A | 70 | RoW | Plasma exchange (PE), intravenous immunmoglobulin (IVIG), intravenous methylprednisolone (IVMP) | Xuanwu Hospital, Beijing | Autoimmune Encephalitis | 12/22 | 09/24 | | |
NCT03703284: Molecular Mechanisms of Malignant Cerebral Edema After LHI |
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| Recruiting | N/A | 120 | RoW | Treatments to reduce intracranial pressure | Xuanwu Hospital, Beijing | Cerebral Edema | 12/22 | 06/23 | | |
UltraFuture I, NCT05498740: Post-marketing Study in Femoral Popliteal Artery of Drug Coated Balloon Used for Treatment of Lower Limb Ischemia |
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| Recruiting | N/A | 200 | RoW | Drug eluting Balloon | Zhejiang Zylox Medical Device Co., Ltd. | Peripheral Arterial Disease (PAD) | 12/22 | 12/24 | | |
NCT05447572: FIT Combining FC for Predicting MH and Histology Remission in UC |
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| Recruiting | N/A | 300 | RoW | FIT + FC | Shandong University | Ulcerative Colitis, Histology Remission, Fecal Calprotetin, FIT, Mucosal Healing | 12/22 | 12/23 | | |
NCT04361357: The Effects of Enteral Whey Protein Supplement on Serum Albumin Level in Acute Critically Ill Neurological Patients |
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| Recruiting | N/A | 116 | RoW | whey protein | Xuanwu Hospital, Beijing | Nutrition Disorders, Neurologic Disorder | 12/22 | 12/22 | | |
NCT05840861: Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders |
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| Recruiting | N/A | 59 | RoW | Vortioxetine, Quetiapine | Central South University | Major Depressive Disorder, Bipolar Disorder | 08/23 | 09/23 | | |
DELTA, NCT05608655: DKutting Balloon Versus Chocolate Balloon to Treat Femoral and Popliteal Artery Stenosis |
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| Completed | N/A | 188 | RoW | DKutting LL balloon, Chocolate balloon | DK Medical Technology (Suzhou) Co., Ltd. | Femoral Artery Stenosis, Popliteal Artery Stenosis | 01/24 | 02/24 | | |
BIATICH, NCT05593380: The Effect of BIA Monitoring of Brain Edema on the Neurological Prognosis of Supratentorial Massive ICH |
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| Recruiting | N/A | 190 | RoW | Parenchymal Intracranial pressure monitor, Integra Life Sciences Camino Intracranial Monitor, Treatment based on clinical and imaging observations | Xiangya Hospital of Central South University | Cerebral Hemorrhage, Hypertensive, Intracranial Hypertension, Monitoring, Critical Care, Treatment Outcome, Invasive Intracranial Pressure Monitoring, Large-volume Cerebral Hemorrhage | 12/24 | 03/25 | | |
NCT06130319: Correlation of Disease Management and Quality of Life in Patients With Chronic Heart Failure and Their Family Caregivers |
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| Recruiting | N/A | 278 | RoW | | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Chronic Heart Failure | 06/24 | 06/24 | | |
| Not yet recruiting | N/A | 768 | RoW | early pancreatic stent placement (EPSP), late pancreatic stent placement (EPSP) | The First Affiliated Hospital of Anhui Medical University, First Affiliated Hospital Bengbu Medical College, Anqing Municipal Hospital, First Affiliated Hospital of Wannan Medical College, Tongcheng People's Hospital of Anhui province, Fuyang people's hospital | Cholangiopancreatography, Endoscopic Rretrograde, Post-ERCP Pancreatitis | 03/26 | 03/26 | | |
NCT06452173: Risk Prediction Model for Cerebrovascular Events in Carotid Artery Stenosis |
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| Enrolling by invitation | N/A | 300 | RoW | Plasma, carotid high-resolution magnetic resonance imaging | Beijing Tiantan Hospital, Beijing Neurosurgical Institute | Carotid Stenosis | 10/26 | 12/26 | | |
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM). |
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| Not yet recruiting | N/A | 1000 | RoW | Continuous Glucose Monitoring System (GX-01S) | Nanjing First Hospital, Nanjing Medical University | Type1 Diabetes Mellitus | 10/26 | 06/27 | | |
NCT05454397: A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients |
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| Recruiting | N/A | 2000 | RoW | Observational study, no intervention | Nanfang Hospital of Southern Medical University, First Affiliated Hospital of Fujian Medical University, Yantai Yuhuangding Hospital, The First Hospital of Jilin University, Qilu Hospital of Shandong University, ZHEJIANG PROVINCE XIAOSHAN HOSPITAL, The First People's Hospital of Wenling, Ganzhou People's Hospital, Affiliated Hospital of Jining Medical hospital, Henan Provincial People's Hospital, Zhongda Hospital Southeast University, The Second Affiliated Hospital of Harbin Medical University, The First people's Hospital of Kunshan, The 2nd Affiliated Hospital of Wenzhou Medical University, THE FIRST PEOPLE'S HOSPITAL OF JIASHAN, The First Affiliated Hospital of Xi'an Jiaotong University Medical College, Fujian Province Zhangzhou Hospital, People's Hospital of Chongqing, Nanjing Zijin Hospital, Hangzhou Red Cross Hospital, Wenzhou Hospital of Chinese Medicine, Kaifeng Central Hospital, First Affiliated Hospital of Guangxi Medical University, Zhongshan Hospital of Xiamen University, Xi'an Encephalopathy of Traditional Chinese Medicine Hospital, 903 Hospital of the Chinese People's Liberation Army Joint Logistics and Security Forces, Xiangya Hospital of Central South University, Second Affiliated Hospital of Suzhou University, Tongji Hospital, The Affiliated Hospital o fQingdao University, The First Affiliated Hospital of Anhui Medical University, Yancheng Third People's Hospital, Linyi People's Hospital, Dongfang Hospital of Beijing University of Chinese Medicine, Affiliated Hospital of Qingdao University | Acute Stroke | 10/22 | 10/23 | | |
| Li, Jing |
BRAVO, NCT05647915: Effects of Berberine in Reducing Abdominal Visceral Adipose Tissue Among Individuals with Obesity and NAFLD |
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| Completed | 4 | 337 | RoW | Berberine plus lifestyle intervention, Placebo plus lifestyle intervention | China National Center for Cardiovascular Diseases | Obesity, Obesity, Abdominal, NAFLD | 08/24 | 08/24 | | |
NCT06425120: Effect of Xuesaitong Soft Capsules on Major Risk Factors in Patients With Coronary Heart Disease |
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| Not yet recruiting | 4 | 240 | RoW | Xuesaitong Soft Capsule, LixuwangⓇ, Placebo | China National Center for Cardiovascular Diseases | Coronary Heart Disease | 12/24 | 12/24 | | |
NCT04624854: Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD) |
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| Active, not recruiting | 4 | 8250 | RoW | Clopidogrel and Aspirin dual-antiplatelet therapy, Aspirin monotherapy | Harbin Medical University, Chinese Society of Cardiology, Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Heart Diseases, Syndrome Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Coronary Disease, Vascular Diseases | 04/25 | 04/25 | | |
NCT05965284: Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTCAZAREM) |
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| Recruiting | 4 | 40 | RoW | Azathioprine, Telitacicept, Taiai for commercial name | Chinese SLE Treatment And Research Group | ANCA-associated Vasculitis, Maintenance Therapy | 12/25 | 12/26 | | |
ABCD, NCT05749874: Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus |
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| Not yet recruiting | 4 | 6500 | RoW | Berberine plus lifestyle intervention, Placebo plus lifestyle intervention | China National Center for Cardiovascular Diseases | PreDiabetes, Abdominal Obesity, Hypertension, Dyslipidemias | 12/26 | 12/26 | | |
NCT05962840: Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM) |
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| Recruiting | 4 | 40 | RoW | Telitacicept, Taiai for commercial name, Placebo of Telitacicept | Chinese SLE Treatment And Research Group, Peking Union Medical College Hospital | ANCA Associated Vasculitis | 12/26 | 12/26 | | |
EHTASEOCCS, NCT03373058: Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery |
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| Recruiting | 3 | 310 | RoW | Hyperthermic Intraperitoneal Chemotherapy, HIPEC, cytoreductive surgery, CRS, adjuvant chemotherapy, ACT | Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Henan Provincial People's Hospital, Xiangya Hospital of Central South University, The Third Xiangya Hospital of Central South University, Peking University Cancer Hospital & Institute, Peking University People's Hospital, Cancer Hospital of Guizhou Province, Chinese PLA General Hospital, Hebei Medical University Fourth Hospital, The Second Hospital of Hebei Medical University, West China Second University Hospital, Peking Union Medical College Hospital, First Affiliated Hospital, Sun Yat-Sen University, Henan Cancer Hospital, Tianjin Medical University Cancer Institute and Hospital, The Third Affiliated Hospital of Guangzhou Medical University, Wuhan University, RenJi Hospital, Obstetrics & Gynecology Hospital of Fudan University, Southern Medical University, China, Fourth Affiliated Hospital of Guangxi Medical University, Shandong Cancer Hospital and Institute, Beijing Obstetrics and Gynecology Hospital, Chongqing University Cancer Hospital, Xinqiao Hospital of Chongqing, Wuhan Union Hospital, China, First Affiliated Hospital of Chongqing Medical University, Affiliated Cancer Hospital of Shantou University Medical College | Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma | 07/21 | 07/23 | | |
| Terminated | 3 | 372 | Europe, US, RoW | Pamrevlumab, FG-3019, Placebo | FibroGen | Idiopathic Pulmonary Fibrosis | 09/23 | 09/23 | | |
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| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
SHINY, NCT06157502: Shuxuening Injection in the Treatment With Intravenous Thrombolysis in Patients With Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Shuxuening Injection, Placebo | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 06/25 | 12/26 | | |
TAPIS, NCT06316570: Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Early Dual Antiplatelet Therapy, Ticagrelor and Aspirin, Placebo, Placebo of Ticagrelor and Aspirin | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 12/25 | 12/26 | | |
Be-CLEVER, NCT05976152: Effect of Butyphthalide on Cognitive Level Change After Cerebral Vascular Event-a Randomized Control Trial |
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| Recruiting | 3 | 3200 | RoW | dl-3-butylphthalide, DL-3-n-butylphthalide (NBP), dl-3-butylphthalide placebo, NBP placebo | Fudan University | Stroke, Post-stroke Cognitive Impairment (PSCI) | 12/26 | 12/26 | | |
NCT01592968: Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases |
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| Active, not recruiting | 3 | 88 | US | Cognitive Assessment, Quality-of-Life Assessment, Quality of Life Assessment, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Metastatic Malignant Neoplasm, Metastatic Malignant Neoplasm in the Brain | 09/25 | 09/25 | | |
NHIPEC, NCT05246020: Efficacy of Neoadjuvant Hyperthermic Intraperitoneal Chemotherapy in Advanced High-grade Serous Ovarian Cancer (the Trial) |
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| Recruiting | 2 | 80 | RoW | HIPEC, intravenous chemotherapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Hyperthermic Intraperitoneal Chemotherapy, Neoadjuvant Chemotherapy | 12/22 | 12/24 | | |
NCT02713269: Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients with Spine Metastases At Risk for Compressing the Spinal Cord |
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| Active, not recruiting | 2 | 60 | US | Computed Tomography, CAT, CAT Scan, Computerized Axial Tomography, computerized tomography, CT, CT SCAN, tomography, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Thermal Ablation Therapy, thermal ablation | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma, Metastatic Kidney Carcinoma, Metastatic Malignant Neoplasm in the Spine, Metastatic Malignant Neoplasm of Unknown Primary, Metastatic Melanoma, Prostate Carcinoma Metastatic in the Bone, Sarcoma, Solid Neoplasm, Spinal Cord Compression, Stage IV Breast Cancer AJCC V6 and V7, Stage IV Lung Non-Small Cell Cancer AJCC V7, Thyroid Gland Carcinoma | 08/25 | 08/25 | | |
NCT06205927: Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer |
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| Recruiting | 2 | 77 | RoW | Standard carbon ion beam radiotherapy, Carbon ion beam radiotherapy simultaneously dose boost | Jian Chen | Non-small Cell Lung Cancer | 12/24 | 12/26 | | |
NCT06206278: Evaluation of Infigratinib in Patients With Locally Advanced or Metastatic Gastric Cancer or GEJ Adenocarcinoma |
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| Terminated | 2 | 6 | RoW | Infigratinib, BGJ398, BBP-831 | LianBio LLC | Gastric Cancer, Gastroesophageal Junction Adenocarcinoma | 05/24 | 05/24 | | |
NCT06186726: Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial Tumors |
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| Recruiting | 2 | 48 | RoW | carbon ion radiotherapy | Jian Chen | Carbon Ion Radiotherapy, Thymoma, Thymic Carcinoma, Radiotherapy, Chemotherapy | 12/26 | 12/29 | | |
NCT06311981: Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients |
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| Recruiting | 2 | 29 | RoW | carbon ion radiotherapy, targeted therapy, single regimen chemotherapy in sequence with radiotherapy | Jian Chen | Non-small Cell Lung Cancer, Older People, Carbon Ion Radiotherapy, Radiotherapy Side Effect | 06/25 | 06/26 | | |
NCT06311955: Clinical Study of Postoperative Carbon Ion Radiotherapy for Thymus Tumor With Residual Tumor |
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| Recruiting | 2 | 48 | RoW | Carbon ion radiotherapy, combined with platinum-based regimen | Jian Chen | Thymic Epithelial Tumor, Radiotherapy Side Effect, Carbon Ion Radiotheray, Heavy Ion Radiotherapy | 02/28 | 02/29 | | |
NCT06311968: The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor |
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| Recruiting | 2 | 55 | RoW | Proton radiotherapy, combined platinum based chemotherapy | Jian Chen | Thymus Epithelial Tumor, Proton Radiotherapy, Radiation Toxicity | 02/27 | 02/27 | | |
| Not yet recruiting | 2 | 120 | RoW | Metformin Hydrochloride tablet, Metformin, Placebo | Xuanwu Hospital, Beijing, Institute of Zoology, Chinese Academy of Sciences, Beijing Institute of Genomics, Chinese Academy of Sciences, Merck Serono Co., Ltd., China | Metformin, Aging | 09/26 | 07/28 | | |
| Active, not recruiting | 2 | 49 | US | Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Clinical Stage IV Cutaneous Melanoma AJCC V8, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Pathologic Stage IV Cutaneous Melanoma AJCC V8 | 08/26 | 08/26 | | |
NCT05593575: Efficacy and Safety of SPH3127 Tablets on Treating the Diabetic Kidney Disease |
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| Recruiting | 2 | 320 | RoW | SPH3127+SPH3127matching placebo+valsartan matching placebo, SPH3127+valsartan matching placebo, SPH3127 matching placebo+valsartan | Shanghai Pharmaceuticals Holding Co., Ltd | Diabetic Kidney Disease | 06/25 | 06/25 | | |
NCT04516070: Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis |
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| Active, not recruiting | 2 | 55 | US | Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, Stereotactic Radiation Therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8 | 12/26 | 12/26 | | |
NCT05613452: Carbon Ion Therapy for Peripheral Non-small Cell Lung Cancer |
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| Recruiting | 2 | 43 | RoW | Carbon ion beam radiotherapy | Shanghai Proton and Heavy Ion Center | Non-small Cell Lung Cancer | 01/25 | 01/26 | | |
NCT06036966: The Efficacy and Safety of Hetrombopag in Primary Prevention of Thrombocytopenia Induced by the Niraparib Maintenance in Advanced Ovarian Cancer Patients |
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| Not yet recruiting | 2 | 34 | NA | Hetrombopag | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Thrombocytopenia | 07/25 | 07/25 | | |
FRUSICA-1, NCT03903705: : A Phase Ib/II Study To Evaluate Fruquintinib Monotherapy Or Plus Sintilimab In Advanced Solid Tumors |
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| Recruiting | 1/2 | 381 | RoW | Fruquintinib in Combination with Sintilimab, Fruquintinib | Hutchmed | Advanced Solid Tumor | 12/25 | 12/25 | | |
| Recruiting | 1/2 | 180 | RoW | MG-K10, Placebo | Shanghai Mabgeek Biotech.Co.Ltd | Asthma | 12/23 | 06/24 | | |
NCI-2016-00661, NCT02696993: Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer |
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| Active, not recruiting | 1/2 | 80 | US | Cognitive Assessment, Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, BMS-734016, MDX-010, MDX-CTLA4, Yervoy, Laboratory Biomarker Analysis, Nivolumab, BMS-936558, MDX-1106, NIVO, ONO-4538, Opdivo, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy | M.D. Anderson Cancer Center | Metastatic Malignant Neoplasm in the Brain, Stage IV Non-Small Cell Lung Cancer AJCC v7 | 12/24 | 12/24 | | |
NCT04592458: Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients |
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| Not yet recruiting | 1 | 10 | RoW | β-globin restored autologous HSC | BGI-research, Shenzhen Children's Hospital | β-Thalassemia Major | 11/22 | 11/24 | | |
| Recruiting | N/A | 100 | RoW | Automated peritoneal dialysis, Intermittent hemodialysis | Limeng Chen, First Hospital of China Medical University, First Affiliated Hospital Xi'an Jiaotong University, Beijing Anzhen Hospital, Xiangya Hospital of Central South University, Baxter Healthcare Corporation | Acute Kidney Injury | 12/22 | 12/22 | | |
NCT04682795: Comparison of Safety and Efficacy of Needle-Free Injector and Insulin Pen in Patients With T2DM |
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| Recruiting | N/A | 200 | RoW | Needle-free injector, Insulin pen | Second Affiliated Hospital, School of Medicine, Zhejiang University | T2DM (Type 2 Diabetes Mellitus), Needle-free Injector, Time in Range | 12/22 | 12/22 | | |
ESPRIT, NCT04030234: Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs () Study |
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| Completed | N/A | 11255 | RoW | Intensive BP treatment group, Control of SBP to <120 mmHg, Standard BP treatment group, Control of SBP to <140 mmHg | China National Center for Cardiovascular Diseases | Hypertension | 06/23 | 07/23 | | |
NCT05352633: Effects of Intensive Systolic Blood Pressure Lowering Treatment on Out-of-office Blood Pressure - an Ancillary Study to Effects of Intensive Systolic Blood Pressure Lowering Treatment in Reducing RIsk of Vascular evenTs (ESPRIT) Study |
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| Not yet recruiting | N/A | 710 | RoW | Intensive BP Arm, Control of SBP to <120 mmHg, Standard BP Arm, Control of SBP to <140 mmHg | China National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, People's Republic of China | Blood Pressure | 09/23 | 09/23 | | |
PERFECT, NCT06181552: Development of CV Risk Prediction Tools Based on AI and Fundus Imaging Technology Study |
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| Not yet recruiting | N/A | 1072 | NA | fundus photograpgy, optical coherence tomography, OCT, optical coherence tomography angiography, OCT-A | China National Center for Cardiovascular Diseases, Beijing Tongren Hospital | Cardiovascular Diseases | 03/25 | 06/25 | | |
FUTURE, NCT05459519: Effects of Dengzhanxixin Capsule on Platelet Function in Individuals at High Risk for Cardiovascular Disease |
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| Recruiting | N/A | 165 | RoW | Dengzhanxixin Capsule plus Placebo Capsule, Placebo | China National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medial Sciences, Shenzhen, Shenzhen | Diabetes, Hypertension, Hypercholesterolemia | 12/23 | 12/23 | | |
NCT05722275: Prediction of Peritoneal Metastasis for Gastric Cancer Based on Radiomics |
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| Recruiting | N/A | 400 | Europe, RoW | Peritoneal metastasis status ascertainment | Chinese Academy of Sciences, Peking University Cancer Hospital & Institute, Zhenjiang First People's Hospital, The First Affiliated Hospital of Zhengzhou University, Nanfang Hospital of Southern Medical University, Guizhou Provincial People's Hospital, Henan Cancer Hospital, Yunnan Cancer Hospital, Guangdong Provincial People's Hospital, Guangzhou Medical University, Fujian Medical University Union Hospital, Shanxi Province Cancer Hospital, Sun Yat-sen University, Beihang University, Scientific Institute San Raffaele | Gastric Cancer, Peritoneal Metastases | 12/23 | 12/28 | | |
NCT06422052: Epidemiological Investigation of Helicobacter Pylori-infected Patients and the Effect of Eradication Treatment on Dyspepsia Symptoms |
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| Recruiting | N/A | 2242 | RoW | Epidemiological questionnaire and Functional Dyspepsia Symptom Diary（FDSD） | Shanghai Jiao Tong University School of Medicine | Helicobacter Pylori Infection, Dyspepsia | 05/25 | 05/25 | | |
NutriConnect, NCT06263751: Comparing the Effectiveness of Two Produce Prescription Approaches On Fruit and Vegetable Intake and Food Security, While Exploring Implementation Outcomes Such as Reach, Implementation, Sustainability, and Cost |
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| Recruiting | N/A | 240 | US | Product prescription program- NutriConnect Credit, Product prescription program- NutriConnect Delivery | Washington University School of Medicine, Schnuck Markets, Inc., BJC HealthCare | Food Insecurity | 03/25 | 06/25 | | |
NCT06163092: Chronic Endometritis and Benefits of Antibiotics in Women With Recurrent Miscarriage |
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| Not yet recruiting | N/A | 175 | RoW | | Chinese University of Hong Kong | Recurrent Miscarriage | 01/26 | 01/27 | | |
NCT05783986: Developing a MRI-based Deep Learning Model to Predict MMR Status |
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| Not yet recruiting | N/A | 600 | NA | randomly divided | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Sun Yat-sen University | Endometrial Cancer | 06/24 | 12/24 | | |
NCT06622798: Exploratory Study on the Correlation Between HRD Score and PARPi Efficacy Based on Chinese Ovarian Cancer Patients |
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| Recruiting | N/A | 470 | RoW | Non-interventional | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Amoy Diagnostics Co., LTD | Exploring the Correlation of HRD Score Pairs with the Prognosis of Chinese Ovarian Cancer Patients and the Outcome of Maintenance Therapy with PARPi | 01/25 | 07/26 | | |
NCT06035250: AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy |
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| Recruiting | N/A | 200 | Europe, RoW | Neoadjuvant Chemotherapy | Chinese Academy of Sciences, Peking University Cancer Hospital & Institute, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Yunnan Cancer Hospital, Henan Cancer Hospital, Zhenjiang First People's Hospital, First Hospital of China Medical University, Cancer Hospital of Guangxi Medical University, Peking University People's Hospital, Tianjin Medical University Cancer Institute and Hospital, The First Affiliated Hospital of Zhengzhou University, Nanfang Hospital, Southern Medical University, The Affiliated Hospital of Qingdao University, Ruijin Hospital, Sixth Affiliated Hospital, Sun Yat-sen University, Peking Union Medical College Hospital, Xiangya Hospital of Central South University, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, The First Affiliated Hospital of Soochow University, First Affiliated Hospital, Sun Yat-Sen University, Fujian Medical University Union Hospital, Fujian Cancer Hospital, San Raffaele University Hospital, Italy | Gastric Cancer, Image, Pathology | 08/24 | 12/29 | | |
| Recruiting | N/A | 216 | RoW | Baduanjin, Brisk walking | China National Center for Cardiovascular Diseases | Elevated Blood Pressure | 12/24 | 12/25 | | |
NCT05570071: A Study of the Use of Vaginal Radiofrequency Therapy in Treatment of SUI. |
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| Not yet recruiting | N/A | 90 | NA | physical therapy | Qianfoshan Hospital | Urinary Incontinence, Stress | 03/25 | 03/25 | | |
NCT06025045: Dynamic Monitoring of ctDNA Predicts Recurrence of Advanced Ovarian Cancer After Primary Treatments |
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| Recruiting | N/A | 50 | RoW | | Jing Li, Nanjing Shihejiyin Technology, Inc. | Ovarian Cancer Stage IV, Ovarian Cancer Stage III | 08/25 | 08/25 | | |
CHAPERONE, NCT05965115: The China M-protein Screening Project in First-degree Relatives of Myeloma Patient - The Study |
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| Recruiting | N/A | 10000 | RoW | Sample of Blood | Shanghai Zhongshan Hospital | Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance | 08/25 | 08/35 | | |
NCT05613049: Confounding Factors of Chronic Endometritis in Women With Reproductive Failure |
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| Recruiting | N/A | 720 | RoW | | Chinese University of Hong Kong | IVF | 07/27 | 01/28 | | |
NCT05153603: Outcomes of First-line Olaparib Mono-maintenance therapy-a Multicenter, Retrospective Study Using Data From Real-world Clinical Setting |
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| Not yet recruiting | N/A | 50 | NA | Olaparib mono-maintenance therapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Ovarian Neoplasms | 09/22 | 12/22 | | |
| Not yet recruiting | N/A | 300 | NA | Neonatal hyperbilirubinemia | Shanghai First Maternity and Infant Hospital | Jaundice, Neonatal | 09/22 | 09/22 | | |
| Wang, Yan |
NCT06256289: Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome |
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| Not yet recruiting | 4 | 50 | NA | Canagliflozin 100mg Tab, Invokana, Metformin Hydrochloride, Glucophage | Ping Li,MD | Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease | 04/25 | 04/25 | | |
NCT05042375: A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer |
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| Recruiting | 3 | 450 | RoW | camrelizumab + famitinib, pembrolizumab, camrelizumab | Jiangsu HengRui Medicine Co., Ltd. | Non-small Cell Lung Cancer | 12/23 | 12/25 | | |
NCT06300177: D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure |
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| Recruiting | 3 | 522 | RoW | D-1553 Tablet, Docetaxel injection | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Non Small Cell Lung Cancer | 10/26 | 12/27 | | |
| Recruiting | 3 | 700 | US | Apixaban, Eliquis, Aspirin | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage, Atrial Fibrillation | 04/27 | 04/27 | | |
| Completed | 3 | 257 | RoW | Tirzepatide, LY3298176, Placebo | Eli Lilly and Company | Diabetes Type 2, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System Diseases | 07/24 | 07/24 | | |
NCT06738979: A Clinical Study Comparing Semaglutide Injection and Wegovy® for Weight Management in Obese Subjects |
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| Not yet recruiting | 3 | 408 | RoW | TQF3510 (Semaglutide Injection), Wegovy® | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Obesity | 07/26 | 08/26 | | |
