| Cottin, Vincent |
| Recruiting | 4 | 378 | Europe | pirfenidone and nintedanib, pirfenidone or nintedanib | Hospices Civils de Lyon, Ministry of Health | Progressive Idiopathic Pulmonary Fibrosis | 01/26 | 01/26 | | |
| Recruiting | 3 | 1000 | Europe, Canada, US, RoW | Ralinepag, APD811, Placebo | United Therapeutics | PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease | 12/25 | 12/25 | | |
| Active, not recruiting | 3 | 160 | Europe, Canada, Japan, US, RoW | Molgramostim, Recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF), Placebo | Savara Inc., Savara ApS, | Autoimmune Pulmonary Alveolar Proteinosis | 11/23 | 11/24 | | |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
EXAFIP2, NCT05674994: Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 110 | Europe | Methylprednisone/Prednisone, Placebo | Fondation Hôpital Saint-Joseph | Acute Exacerbation of Idiopathic Pulmonary Fibrosis | 10/25 | 12/26 | | |
| Terminated | 2/3 | 202 | Europe, Canada, US, RoW | AV-101, Placebo | Aerovate Therapeutics, Aerovate Therapeutics, Inc. | Pulmonary Arterial Hypertension | 08/24 | 08/24 | | |
| Completed | 2 | 108 | Europe, Canada, US, RoW | rodatristat ethyl 300 mg tablet BID, rodatristat ethyl 600 mg BID, Placebo | Altavant Sciences GmbH | Pulmonary Arterial Hypertension | 06/23 | 08/23 | | |
| Recruiting | N/A | 2500 | Europe | | Institut National de la Santé Et de la Recherche Médicale, France | Idiopathic Interstitial Pneumopathy/Pneumopathy Interstitial Diffuse, Paediatric and Adult Patients | 03/21 | 09/21 | | |
| Completed | N/A | 140 | Europe | Blood sample, Low or upper respiratory tract sample, Stool collection or fecal swab, phone call | Hospices Civils de Lyon | Infection, Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 | 05/22 | 05/22 | | |
I-FILE, NCT04304898: An International Patient-led Registry in Fibrotic Interstitial Lung Diseases Using eHealth Technology |
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| Recruiting | N/A | 700 | Europe | Home spirometry | Erasmus Medical Center | Pulmonary Fibrosis | 07/25 | 07/26 | | |
| Recruiting | N/A | 200 | Europe | | Vincent COTTIN, Hospices Civils de Lyon | Lymphangioleiomyomatosis | 12/24 | 12/25 | | |
| Completed | N/A | 203 | Europe | Oral anticoagulant treatment, warfarin (Coumadine®), fluindione (Préviscan®), acenocoumarol (Sintrom®) | Centre Hospitalier Universitaire de Saint Etienne | Pulmonary Arterial Hypertension | 09/22 | 09/23 | | |
ILDnose, NCT04680832: Exhaled Breath Analysis Using eNose Technology as a Biomarker for Diagnosis and Disease Progression in Fibrotic ILD |
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| Recruiting | N/A | 600 | Europe | Electronic nose, SpiroNose, eNose | Erasmus Medical Center | Pulmonary Fibrosis | 12/25 | 12/26 | | |
| Completed | N/A | 49 | Europe | Rehabilitation, Supervised rehabilitation | Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France | Pulmonary Arterial Hypertension | 12/22 | 01/24 | | |
MAINEPSAN, NCT03290456 / 2018-001215-69: Evaluate the Remission MAINtenance Using Extended Administration of Prednisone in Systemic Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis. |
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| Recruiting | N/A | 146 | Europe | Prednisone 5mg/day extended of 12 additional months, Placebo 5mg/day extended of 12 additionnal months. | Hospices Civils de Lyon, Ministry of health | Granulomatosis With Polyangitis | 06/24 | 06/24 | | |
| Completed | N/A | 86 | Europe | Elemental analysis | University Hospital, Grenoble | Interstitial Lung Disease, Sarcoidosis, Idiopathic Pulmonary Fibrosis | 04/24 | 04/24 | | |
| Recruiting | N/A | 300 | Europe | | Institut National de la Santé Et de la Recherche Médicale, France | Primary Ciliary Dyskinesia | 05/27 | 05/27 | | |
| Recruiting | N/A | 3000 | Europe | | Institut National de la Santé Et de la Recherche Médicale, France | Interstitial Lung Diseases | 03/31 | 03/31 | | |
| REYNAUD-GAUBERT, Martine |
| Recruiting | 4 | 378 | Europe | pirfenidone and nintedanib, pirfenidone or nintedanib | Hospices Civils de Lyon, Ministry of Health | Progressive Idiopathic Pulmonary Fibrosis | 01/26 | 01/26 | | |
| Completed | 3 | 220 | Europe, US, RoW | Liposomal Cyclosporine A, L-CsA, Standard of Care, SoC | Zambon SpA, BREATH Therapeutics Inc. | Bronchiolitis Obliterans, Chronic Rejection of Lung Transplant, Lung Transplant Rejection, Lung Transplant; Complications, Lung Transplant Failure and Rejection, Chronic Lung Allograft Dysfunction | 03/24 | 03/24 | | |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
| Terminated | 2/3 | 202 | Europe, Canada, US, RoW | AV-101, Placebo | Aerovate Therapeutics, Aerovate Therapeutics, Inc. | Pulmonary Arterial Hypertension | 08/24 | 08/24 | | |
NCT05032066: A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis |
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| Terminated | 2 | 153 | Europe, Canada, Japan, US, RoW | HZN-825, Placebo | Amgen | Idiopathic Pulmonary Fibrosis | 07/24 | 01/25 | | |
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| Recruiting | N/A | 300 | Europe | | Institut National de la Santé Et de la Recherche Médicale, France | Primary Ciliary Dyskinesia | 05/27 | 05/27 | | |
| Diaz, Cristina Caballero |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
NCT05032066: A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis |
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| Terminated | 2 | 153 | Europe, Canada, Japan, US, RoW | HZN-825, Placebo | Amgen | Idiopathic Pulmonary Fibrosis | 07/24 | 01/25 | | |
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| Ramirez, Alicia |
| Recruiting | 3 | 1000 | Europe, Canada, US, RoW | Ralinepag, APD811, Placebo | United Therapeutics | PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease | 12/25 | 12/25 | | |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
NCT05032066: A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis |
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| Terminated | 2 | 153 | Europe, Canada, Japan, US, RoW | HZN-825, Placebo | Amgen | Idiopathic Pulmonary Fibrosis | 07/24 | 01/25 | | |
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| DRUCBERT, Mélanie |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
| Rivera, Alicia Ramirez |
| Terminated | 3 | 186 | Europe, Canada, US, RoW | AV-101 | Aerovate Therapeutics, Aerovate Therapeutics Inc | Pulmonary Arterial Hypertension | 08/24 | 08/24 | | |
| Terminated | 2/3 | 202 | Europe, Canada, US, RoW | AV-101, Placebo | Aerovate Therapeutics, Aerovate Therapeutics, Inc. | Pulmonary Arterial Hypertension | 08/24 | 08/24 | | |
| Wilpotte, Celine |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
| Namouri, Yasmine |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
| Benmostafa, Chahinez |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
