University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center
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 128 Trials 
223 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Machtay, Mitchell
NCT00956007: RT With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer

Active, not recruiting
3
702
Canada, US, RoW
cetuximab, intensity-modulated radiation therapy
Radiation Therapy Oncology Group, National Cancer Institute (NCI), NRG Oncology
Head and Neck Cancer
09/23
08/29
NCT03811015: Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Suspended
3
636
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Fludeoxyglucose F-18, 18FDG, FDG, Fludeoxyglucose (18F), fludeoxyglucose F 18, Fludeoxyglucose F18, Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, Fluorodeoxyglucose F18, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Patient Observation, Active Surveillance, deferred therapy, expectant management, Observation, Watchful Waiting, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT
National Cancer Institute (NCI)
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
01/27
01/27
S1914, NCT04214262: Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer

Active, not recruiting
3
480
US
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG 7446, RG-7446, RG7446, RO 5541267, RO-5541267, RO5541267, Tecentriq, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Fludeoxyglucose F-18, 18FDG, FDG, Fludeoxyglucose (18F), fludeoxyglucose F 18, Fludeoxyglucose F18, Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, Fluorodeoxyglucose F18, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Body Radiation Therapy, SABR, SBRT, Stereotactic Ablative Body Radiation Therapy
National Cancer Institute (NCI)
Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8
05/28
05/28
NRG-HN005, NCT03952585: De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Active, not recruiting
2/3
384
Canada, US
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Fludeoxyglucose F-18, 18FDG, FDG, Fludeoxyglucose (18F), fludeoxyglucose F 18, Fludeoxyglucose F18, Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, Fluorodeoxyglucose F18, Image Guided Radiation Therapy, IGRT, image-guided radiation therapy, Image-Guided Radiotherapy, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration
National Cancer Institute (NCI), NRG Oncology
Basaloid Squamous Cell Carcinoma, Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Oropharyngeal Squamous Cell Carcinoma, Papillary Squamous Cell Carcinoma, Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Squamous Cell Carcinoma
03/24
12/25
RTOG 1216, NCT01810913: Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Recruiting
2/3
613
Canada, US, RoW
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG 7446, RG-7446, RG7446, RO 5541267, RO-5541267, RO5541267, Tecentriq, Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cetuximab, C 225, C-225, C225, Cetuximab Biosimilar CDP-1, Cetuximab Biosimilar CMAB009, Cetuximab Biosimilar KL 140, Chimeric Anti-EGFR Monoclonal Antibody, Chimeric MoAb C225, Chimeric Monoclonal Antibody C225, Erbitux, IMC-C225, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Docetaxel, Docecad, RP 56976, RP-56976, RP56976, Taxotere, Taxotere Injection Concentrate, Intensity-Modulated Radiation Therapy, IMRT, Intensity modulated radiation therapy (procedure), Intensity Modulated RT, Intensity-Modulated Radiotherapy, Radiation, Intensity-Modulated Radiotherapy, Laboratory Biomarker Analysis, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Quality-of-Life Assessment, Quality of Life Assessment
National Cancer Institute (NCI), NRG Oncology
Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7, Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7
01/27
01/27
RAPTOR, NCT04402788: Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The Trial

Recruiting
2/3
138
US
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG 7446, RG-7446, RG7446, RO 5541267, RO-5541267, RO5541267, Tecentriq, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Radiation Therapy, Cancer Radiotherapy, Energy Type, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation
National Cancer Institute (NCI), NRG Oncology
Extensive Stage Lung Small Cell Carcinoma
04/27
04/27
NCT04929041: Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

Recruiting
2/3
427
US
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, BMS 734016, BMS-734016, BMS734016, Ipilimumab Biosimilar CS1002, MDX 010, MDX-010, MDX-CTLA4, MDX010, Yervoy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Quality-of-Life Assessment, Quality of Life Assessment, Radiation Therapy, Cancer Radiotherapy, Energy Type, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation
National Cancer Institute (NCI)
Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8
12/27
12/27
JANUS, NCT05610163: Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation

Recruiting
2
312
US
Capecitabine, 5-fluorouracil, Leucovorin calcium, Irinotecan, Oxaliplatin, Long Course Chemoradiotherapy, Computed Tomography, Magnetic Resonance Imaging, Sigmoidoscopy, biopsy
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Locally Advanced Rectal Carcinoma, Stage II Rectal Cancer AJCC V8, Stage III Rectal Cancer AJCC V8
09/25
09/32
GRECO-2, NCT04698915: Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer

Terminated
2
177
Europe, Canada, US
Drug GC4711, Placebo
Galera Therapeutics, Inc.
SBRT, Borderline Resectable Pancreatic Cancer, Unresectable Pancreatic Cancer
11/23
11/23
NCT06086925: A Window of Opportunity Study of Black Raspberry for Patients With HNSCC

Not yet recruiting
1
30
NA
Black Raspberry, BRB
Mitchell Machtay
Squamous Cell Carcinoma of the Oral Cavity or Oropharynx
06/27
12/27
NCT05540899: Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer

Recruiting
1
15
US
Hypofractionated Postoperative Radiotherapy, H-PORT
American College of Radiology, RTOG Foundation, Inc.
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Larynx, Squamous Cell Carcinoma of the Oropharynx, Squamous Cell Carcinoma of the Oral Cavity
11/27
11/28
NCT05334069: Collecting Blood Samples from Patients with and Without Cancer to Evaluate Tests for Early Cancer Detection

Recruiting
N/A
2000
US
Questionnaire Administration, Biospecimen Collection
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Ann Arbor Stage I Lymphoma, Ann Arbor Stage II Lymphoma, Ann Arbor Stage III Lymphoma, Ann Arbor Stage IV Lymphoma, Chronic Lymphocytic Leukemia, Chronic Myeloid Leukemia, Gastroesophageal Junction Adenocarcinoma, Head and Neck Carcinoma, Hematopoietic and Lymphoid Cell Neoplasm, Invasive Breast Carcinoma, Kidney Carcinoma, Malignant Hepatobiliary Neoplasm, Malignant Solid Neoplasm, Melanoma, Muscle-Invasive Bladder Carcinoma, RISS Stage I Plasma Cell Myeloma, RISS Stage II Plasma Cell Myeloma, RISS Stage III Plasma Cell Myeloma, Sarcoma, Stage I Bladder Cancer AJCC V6 and V7, Stage I Breast Cancer AJCC V7, Stage I Colorectal Cancer AJCC V6 and V7, Stage I Esophageal Cancer AJCC V7, Stage I Gastric Cancer AJCC V7, Stage I Lung Cancer AJCC V7, Stage I Ovarian Cancer AJCC V6 and V7, Stage I Pancreatic Cancer AJCC V6 and V7, Stage I Prostate Cancer AJCC V7, Stage I Uterine Corpus Cancer AJCC V7, Stage II Bladder Cancer AJCC V6 and V7, Stage II Breast Cancer AJCC V6 and V7, Stage II Colorectal Cancer AJCC V7, Stage II Esophageal Cancer AJCC V7, Stage II Gastric Cancer AJCC V7, Stage II Lung Cancer AJCC V7, Stage II Ovarian Cancer AJCC V6 and V7, Stage II Pancreatic Cancer AJCC V6 and V7, Stage II Prostate Cancer AJCC V7, Stage II Uterine Corpus Cancer AJCC V7, Stage III Bladder Cancer AJCC V6 and V7, Stage III Breast Cancer AJCC V7, Stage III Colorectal Cancer AJCC V7, Stage III Esophageal Cancer AJCC V7, Stage III Gastric Cancer AJCC V7, Stage III Lung Cancer AJCC V7, Stage III Ovarian Cancer AJCC V6 and V7, Stage III Pancreatic Cancer AJCC V6 and V7, Stage III Prostate Cancer AJCC V7, Stage III Uterine Corpus Cancer AJCC V7, Stage IV Bladder Cancer AJCC V7, Stage IV Breast Cancer AJCC V6 and V7, Stage IV Colorectal Cancer AJCC V7, Stage IV Esophageal Cancer AJCC V7, Stage IV Gastric Cancer AJCC V7, Stage IV Lung Cancer AJCC V7, Stage IV Ovarian Cancer AJCC V6 and V7, Stage IV Pancreatic Cancer AJCC V6 and V7, Stage IV Prostate Cancer AJCC V7, Stage IV Uterine Corpus Cancer AJCC V7, Thyroid Gland Carcinoma
01/26
02/27
ALCHEMIST Screening, NCT02194738: Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The Trial)

Recruiting
N/A
8300
US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Clinical Observation, observation, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Crizotinib, Alkixen, Crizocent, MET Tyrosine Kinase Inhibitor PF-02341066, PF 02341066, PF-02341066, PF-2341066, PF02341066, Xalkori, Cytology Specimen Collection Procedure, Cytologic Sampling, Echocardiography, EC, Erlotinib, Gemcitabine Hydrochloride, dFdCyd, Difluorodeoxycytidine Hydrochloride, Gemcitabine HCI, Gemzar, LY 188011, LY-188011, LY188011, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Pembrolizumab, BCD-201, GME 751, GME751, Keytruda, Lambrolizumab, MK 3475, MK-3475, MK3475, Pembrolizumab Biosimilar BCD-201, Pembrolizumab Biosimilar GME751, Pembrolizumab Biosimilar QL2107, Pembrolizumab Biosimilar RPH-075, QL2107, RPH 075, RPH-075, RPH075, SCH 900475, SCH-900475, SCH900475, Pemetrexed, MTA, Multitargeted Antifolate, Pemfexy, Pemetrexed Disodium, Alimta, Almita, LY231514, N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt, Placebo Administration, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT
National Cancer Institute (NCI)
Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage II Lung Non-Small Cell Cancer AJCC v7, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Cancer AJCC v8
09/26
09/26
Sloan, Andrew E
SENTRY, NCT04562389: Study of Selinexor in Combination with Ruxolitinib in Myelofibrosis

Checkmark Presentation of data from Phase 1 trial for 1L Myelofibrosis at ASH 2022
Dec 2022 - Dec 2022: Presentation of data from Phase 1 trial for 1L Myelofibrosis at ASH 2022
Hourglass Dec 2022 - Dec 2022 : Data from trial in combination with ruxolitinib myelofibrosis
Checkmark Data from trial in combination with ruxolitinib myelofibrosis at ASH 2022
Dec 2022 - Dec 2022: Data from trial in combination with ruxolitinib myelofibrosis at ASH 2022
More
Recruiting
3
350
Europe, Canada, US, RoW
Selinexor, KPT-330, Placebo, Ruxolitinib
Karyopharm Therapeutics Inc
Myelofibrosis
09/25
03/28
TVI-AST-008, NCT05685004: Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

Recruiting
2/3
120
US
TVI-Brain-1, Standard of Care, Radiotherapy, Temozolomide, Chemotherapy
TVAX Biomedical
Glioblastoma Multiforme of Brain
12/26
03/27
hSTAR GBM, NCT05052957: (Hematopoetic Stem Cell (HPC) Rescue for GBM)

Recruiting
2
16
US
P140K-MGMT, O6-benzylguanine, BG, Photon Based Radiotherapy, temozolomide, TMZ, Filgrastim, G-CSF,Granulocyte-Colony Stimulating Factor, carmustine, BCNU,bis-chloronitrosourea
Leland Metheny, National Cancer Institute (NCI)
Glioblastoma Multiforme, Glioblastoma Multiforme, Adult, Supratentorial Glioblastoma, Supratentorial Gliosarcoma
06/25
12/25
ImmuneSense, NCT04485949: A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma

Active, not recruiting
2
93
US
IGV-001 Cell Immunotherapy, Placebo, Standard of Care (SOC): Radiation Therapy, SOC: Temozolomide
Imvax
Glioblastoma
01/25
07/27
NCT01269424: BG & TMZ Therapy of Glioblastoma Multiforme

Completed
1
10
US
MGMTP140K-encoding retroviral vector, O6-benzylguanine, temozolomide, laboratory biomarker analysis, autologous hematopoietic stem cell transplantation, in vitro-treated peripheral blood stem cell transplantation, radiation therapy
Stanton Gerson MD, National Cancer Institute (NCI)
Glioblastoma Multiforme
12/20
09/22
Krishnamurthi, Smitha
SOLARIS, NCT04094688: Vitamin D3 with Chemotherapy and Bevacizumab in Treating Patients with Advanced or Metastatic Colorectal Cancer

Active, not recruiting
3
455
US
Bevacizumab, Oxaliplatin, Leucovorin Calcium, Fluorouracil, Irinotecan Hydrochloride, Irinotecan, Cholecalciferol, Vitamin D3, Quality-of-Life Assessment, Questionnaire Administration
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Colorectal Adenocarcinoma
01/26
07/26
AZUR-2, NCT05855200: Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

Recruiting
3
711
Europe, Canada, Japan, US, RoW
Dostarlimab, CAPEOX, FOLFOX
GlaxoSmithKline
Colonic Neoplasms, Neoplasms, Colon
12/28
12/30
A022004, NCT05710406: Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Active, not recruiting
2/3
1
US
Encorafenib, Braftovi, LGX-818, Cetuximab, Cetuximab Biosimilar CDP-1, Cetuximab Biosimilar KL 140, Chimeric Monoclonal Antibody C225, Erbitux, Biospecimen Collection, Computed Tomography, CAT Scan, CT Scan, Magnetic Resonance Imaging, MRI, Patient Observation, Watchful Waiting
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Colon Adenocarcinoma, Microsatellite Stable Colon Carcinoma, Stage IIB Colon Cancer AJCC V8, Stage IIC Colon Cancer AJCC V8, Stage III Colon Cancer AJCC V8
06/34
06/34
C-800-25, NCT05608044: A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer

Active, not recruiting
2
234
Europe, US, RoW
Botensilimab, AGEN1181, Balstilimab, AGEN2034, Standard of Care
Agenus Inc.
Metastatic Colorectal Cancer
02/25
07/25
NCT05221320: Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) Malignancies

Terminated
2
47
US
Ulixertinib, BVD-523, BVD523, Hydroxychloroquine
BioMed Valley Discoveries, Inc
Tumor, Solid, Gastrointestinal Cancer
05/24
07/24
NCT05356585: Circulating Tumor DNA to Monitor the Efficacy of Total Neoadjuvant Therapy for Rectal Cancer

Withdrawn
N/A
30
US
SignateraTM assay
Case Comprehensive Cancer Center
Colorectal Cancer, Rectal Cancer
06/24
06/24
Silverman, Paula
NCT00060177: Letrozole With or Without Tipifarnib in Treating Women With Locally Advanced, Locally Recurrent, or Metastatic Breast Cancer

Active, not recruiting
2
US
letrozole, tipifarnib
University Hospitals Seidman Cancer Center, National Cancer Institute (NCI)
Breast Cancer
 
 
Jones, Robert
DETERMINE, NCT05768178: Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.

Recruiting
2/3
30
Europe
Vemurafenib, Zelboraf, Cobimetinib, Cotellic
Cancer Research UK, University of Manchester, University of Birmingham, Royal Marsden NHS Foundation Trust, Hoffmann-La Roche
Solid Tumor, Haematological Malignancy, Melanoma, Thyroid Cancer, Papillary, Ovarian Neoplasms, Colorectal Neoplasms, Laryngeal Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioma, Multiple Myeloma, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic
10/29
10/29
CRUKD/21/004, NCT05722886: DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Recruiting
2/3
825
Europe
Alectinib, Alecensa, Atezolizumab, Tecentriq, Entrectinib, Rozlytrek, Trastuzumab in combination with pertuzumab, Herceptin in combination with Perjeta, Vemurafenib in combination with cobimetinib, Zelboraf in combination with Cotellic
Cancer Research UK, University of Manchester, University of Birmingham, Royal Marsden NHS Foundation Trust, Hoffmann-La Roche
Solid Tumor, Haematological Malignancy
10/29
10/29
DETERMINE, NCT05786716: Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations

Recruiting
2/3
30
Europe
Trastuzumab, Herceptin, Pertuzumab, Perjeta
Cancer Research UK, University of Manchester, University of Birmingham, Royal Marsden NHS Foundation Trust, Hoffmann-La Roche
Solid Tumor, Haematological Malignancy, Colorectal Neoplasms, Urinary Bladder Neoplasm, Gallbladder Neoplasms, Salivary Gland Neoplasm, Lung Neoplasm, Pancreatic Neoplasm, Ovarian Neoplasms, Prostatic Neoplasm, Skin Neoplasm
10/29
10/29
DETERMINE, NCT05770102: Trial Treatment Arm 02: Atezolizumab in Adult, Teenage/Young Adults and Paediatric Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

Recruiting
2/3
30
Europe
Atezolizumab, Tecentriq
Cancer Research UK, University of Manchester, University of Birmingham, Royal Marsden NHS Foundation Trust, Hoffmann-La Roche
Malignancy, Malignant Neoplasm, Lymphoproliferative Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Cancer, Colorectal Neoplasms, Endometrial Neoplasms, Melanoma
10/29
10/29
DETERMINE, NCT05770037: Trial Treatment Arm 01: Alectinib in Adult, Teenage/Young Adults (TYA) and Paediatric Patients With ALK Positive Cancers

Recruiting
2/3
30
Europe
Alectinib, Alecensa
Cancer Research UK, University of Manchester, University of Birmingham, Royal Marsden NHS Foundation Trust, Hoffmann-La Roche
Solid Tumor, Haematological Malignancy, Malignant Neoplasm, Lymphoproliferative Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Cancer, Anaplastic Large Cell Lymphoma, Lymphoma, Renal Cell Carcinoma, Neuroblastoma
10/29
10/29
DETERMINE, NCT05770544: Trial Treatment Arm 03: Entrectinib in Adult, Teenage/Young Adults and Paediatric Patients With ROS1 Gene Fusion-positive Cancers.

Recruiting
2/3
30
Europe
Entrectinib, Rozlytrek
Cancer Research UK, University of Manchester, University of Birmingham, Royal Marsden NHS Foundation Trust, Hoffmann-La Roche
Solid Tumor, Haematological Malignancy, Malignancy, Malignant Neoplasm, Lymphoproliferative Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Cancer, Brain Neoplasms, Melanoma, Glioma
10/29
10/29
KEYNOTE-D78, NCT04879329: A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

Recruiting
2
332
Europe, Canada, Japan, US, RoW
disitamab vedotin, RC48-ADC, pembrolizumab, KEYTRUDA®
Seagen Inc., Merck Sharp & Dohme LLC
Urothelial Carcinoma
11/26
05/28
FAKTION, NCT01992952: Fulvestrant +/- Akt Inhibition in Advanced Aromatase Inhibitor Resistant Breast Cancer

Checkmark From P1b/2 FAKTION trial for advanced ER+/HER2- breast cancer at ASCO 2019 [screenshot]
Jun 2019 - Jun 2019: From P1b/2 FAKTION trial for advanced ER+/HER2- breast cancer at ASCO 2019 [screenshot]
Active, not recruiting
1b/2
149
Europe
AZD5363, Placebo, Fulvestrant
Velindre NHS Trust, AstraZeneca, Cenduit LLC, Covance, Cardiff and Vale University Health Board
Estrogen Receptor Positive Breast Cancer
03/19
12/23
NCT05944237: HTL0039732 in Participants with Advanced Solid Tumours

Recruiting
1/2
150
Europe
HTL0039732 Capsules, HTL0039732 Capsules and atezolizumab infusion
Cancer Research UK, Nxera Pharma UK Limited
Neoplasms, Prostatic Neoplasms, Castration-Resistant, Stomach Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Colorectal Neoplasms, Pancreatic Neoplasms, Lung Neoplasms, Urinary Bladder Neoplasms, Mesothelioma, Malignant, Uterine Cervical Neoplasms, Kidney Neoplasms, Sarcoma, Pheochromocytomas
09/26
09/26
NCT04630262: ATTUNE Cementless FB Tibial Base Clinical Study

Terminated
N/A
80
US
ATTUNE Cementless CR Fixed Bearing, ATTUNE Cementless PS Fixed Bearing
DePuy Orthopaedics
Osteoarthritis of the Knee
03/23
03/23
WAVE, NCT04540302: The Merit WRAPSODY AV Access Efficacy Study

Active, not recruiting
N/A
357
Europe, Canada, US, RoW
Merit WRAPSODY Endovascular Stent Graft, PTA
Merit Medical Systems, Inc.
Venous Stenosis, Venous Occlusion
02/24
01/26
NCT05527483: Digital PET/CT Using [Ga-68]PSMA vs. [F-18]NaF for Evaluation of Osseous Metastatic Involvement in Prostate Cancer Patients

Completed
N/A
32
US
[68Ga]PSMA, Flourine-18 [F-18] Sodium Fluoride (NaF), PET/CT
University Hospitals Cleveland Medical Center
Prostate Cancer
10/22
10/22
Mossie-GO, NCT06232954: Evaluation of the Protective Efficacy of a Spatial Repellent to Reduce Malaria Prevalence in Uganda

Recruiting
N/A
5600
RoW
Mossie-Go containing treated transfluthrin disc, Mossie-Go containing untreated blank disc
Africa Power Limited, Malaria Consortium, ARCTECH INNOVATION LIMITED
Malaria, Mosquito-Borne Disease
09/25
09/25
NCT04682665: Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases

Completed
N/A
81
Europe
Icosapent Ethyl Oral Capsule, Placebo
University of Leeds, National Cancer Institute (NCI), Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard School of Public Health (HSPH), University of Bradford
Colon Cancer Liver Metastasis
07/24
07/24
WRAP, NCT05062291: Merit SODY™ Endoprosthesis for Treatment of Stenosis or Occlusion

Recruiting
N/A
500
Europe, RoW
Merit WRAPSODY Endovascular Stent Graft
Merit Medical Systems, Inc.
Venous Stenosis, Venous Occlusion
12/25
07/27
NCT06797193: Ultrasound with Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension

Not yet recruiting
N/A
60
US
Electronic Health Record Review, Liver Biopsy, Biopsy of Liver, Medical Device Usage and Evaluation, Perflutren Lipid Microspheres, Definity, Ultrasound Imaging, 2-Dimensional Grayscale Ultrasound Imaging, 2-Dimensional Ultrasound Imaging, 2D-US, Ultrasonography, Ultrasound, Ultrasound Test, Ultrasound, Medical, US
Mayo Clinic
Cirrhosis
01/27
01/27
TARGET National, NCT04723316: Tumour Characterisation to Guide Experimental Targeted Therapy - National

Recruiting
N/A
6000
Europe
The Christie NHS Foundation Trust
Cancer
01/26
01/28
NCT04907240: Observational GORE® VIABAHN® Endoprosthesis With PROPATEN Bioactive Surface Global Registry

Recruiting
N/A
614
Europe
GORE® VIABAHN® Endoprosthesis with PROPATEN Bioactive Surface (VSX)
W.L.Gore & Associates
Peripheral Artery Disease, Popliteal Aneurysm, Hemodialysis Access, Visceral Artery Aneurysms, Trauma Injury
10/26
10/35
ACTRN12619000470190p: FLASH.V: Flash Glucose Monitoring and Surgery in the Hepatopancreaticobiliary (HPB) Surgery and Liver Transplant Population - Verification Study

Not yet recruiting
N/A
100
 
University of Melbourne: Department of Surgery , Austin Health Liver Transplant Unit, Austin Medical Research Fund
Liver Transplantation ; Anaesthetics
 
 
ACTRN12619000470190: FLASH.V: Flash Glucose Monitoring and Surgery in the Hepatopancreaticobiliary (HPB) Surgery and Liver Transplant Population - Verification Study

Not yet recruiting
N/A
100
 
University of Melbourne: Department of Surgery , Austin Health Liver Transplant Unit, Austin Medical Research Fund
Liver Transplantation , Anaesthetics
 
 
PINCER, NCT05650125: A Platform Study for solId orgaN CancERs

Recruiting
N/A
2000
Europe
Biosampling
University of Liverpool, Countess of Chester NHS Foundation Trust, Liverpool University Hospitals NHS Foundation Trust, Clatterbridge Centre for Oncology, Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool Womens Hospital
Cancer, Surgery
01/30
01/30
Chak, Amitabh
NCT02476279: Stent vs. Indomethacin for Preventing Post-ERCP Pancreatitis

Completed
3
1950
Canada, US
Indomethacin 100 mg rectally immediately after ERCP, NO prophylactic pancreatic stent placement, Indomethacin 100 mg rectally immediately after ERCP AND prophylactic pancreatic stent placement
Medical University of South Carolina, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Post-ERCP Pancreatitis
01/23
01/23
CAPS5, NCT02000089: The Cancer of the Pancreas Screening-5 )Study

Recruiting
3
9000
US
Secretin, ChiRhoStim, MRI, MRCP, Tumor marker gene test with CA19-9
Johns Hopkins University, National Cancer Institute (NCI), National Institutes of Health (NIH)
Pancreas Cancer, Peutz-Jeghers Syndrome (PJS), Gene Mutation, Germline Mutation Carrier, Lynch Syndrome
10/25
12/25
NCT06732388: Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

Not yet recruiting
2
64
US
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Endoscopic Procedure, Endoscopic Examination, Endoscopy, ES, Itraconazole, Lozanoc, Oriconazole, R 51,211, Sporanox, Placebo Administration, Questionnaire Administration, Radiofrequency Ablation, Ablation, Radiofrequency, Radiofrequency Interstitial Ablation, RFA
National Cancer Institute (NCI)
Barrett Esophagus, Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8, Esophageal Adenocarcinoma
01/28
01/28
NCT04939051: Obeticholic Acid for Prevention in Barrett's Esophagus

Recruiting
2
30
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Esophageal Biopsy, Biopsy of Esophagus, Esophagogastroduodenoscopy, EGD, Upper Endoscopy, Liver Ultrasonographic Elastography, Fibroscan, TE, Transient Elastography, VCTE, Vibration-Controlled Transient Elastrography, Obeticholic Acid, INT-747, Ocaliva, Placebo Administration, Questionnaire Administration
National Cancer Institute (NCI)
Barrett Esophagus, Esophageal Adenocarcinoma
09/25
09/26
NCT04880044: Detection of Barrett s Esophagus in Patients Without GERD Symptoms

Recruiting
N/A
500
US
EsoCheck/EsoGuard (EC/EG), Esophago-gastro-duodenoscopy (EGD)
Case Comprehensive Cancer Center
Barrett's Esophagus
06/25
06/26
NCT05210049: Non-endoscopic Esophageal Sampling to Detect Barrett's Esophagus and Esophageal Cancer in Veterans

Recruiting
N/A
125
US
Esocheck/Esoguard
Cleveland VA Medical Research and Education Foundation, United States Department of Defense
Barrett Esophagus, GERD, Obesity, Esophageal Cancer
08/24
08/24
NCT06687603: Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

Not yet recruiting
N/A
800
US
EsoCheck, EsoGuard
Case Comprehensive Cancer Center
Barrett Esophagus, Gastroesophageal Reflux, Esophageal Adenocarcinoma
09/28
09/29
ReBET, NCT03554356: Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)

Recruiting
N/A
70
US
CryoBalloon Focal Ablation System
University of North Carolina, Chapel Hill, PENTAX of America, Inc., Johns Hopkins University
Barrett Esophagus, Intestinal Metaplasia, Esophageal Dysplasia
12/26
12/26
SURVENT, NCT05753748: Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

Recruiting
N/A
680
US
Endoscopic Eradication Therapy
University of Colorado, Denver, Baylor University, University of North Carolina, Medical University of South Carolina, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Barretts Esophagus With Dysplasia, Barrett Esophagus, Esophageal Adenocarcinoma
02/28
02/28
FBE, NCT00288119: Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

Recruiting
N/A
2000
US
Balloon Capsule Device, Esophageal Sampling Device BESD-001, Endoscopy, EGD
Case Western Reserve University, University Hospitals Cleveland Medical Center, Washington University School of Medicine, Fred Hutchinson Cancer Center, University of Washington, Mercy Medical Center, Johns Hopkins University, Mayo Clinic, University of North Carolina, Chapel Hill, The Cleveland Clinic, University of Pennsylvania, Columbia University, VA Puget Sound Health Care System
Barrett's Esophagus, Esophageal Neoplasm
07/28
07/28
Li, Li
NCT04146155: Efficacy and Safety of Liraglutide in Type 2 Diabetes With Lower Extremity Arterial Disease

Recruiting
4
200
RoW
Liraglutide+standard-of-care treatment, Victoza, standard-of-care treatment
Second Affiliated Hospital, School of Medicine, Zhejiang University
Type 2 Diabetes, Peripheral Vascular Disorder Due to Diabetes Mellitus
12/21
12/21
NCT04713358: Effect of Nalmefene on the Quality of Resuscitation in Patients Under General Anesthesia

Recruiting
4
520
RoW
Nalmefene, normal Saline
RenJi Hospital, Shanghai Tong Ren Hospital, First Affiliated Hospital of Guangxi Medical University, The First Affiliated Hospital of Zhengzhou University
Resuscitation
12/23
12/23
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis

Recruiting
4
364
RoW
Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline
Shanghai Pulmonary Hospital, Shanghai, China
Bronchiectasis Adult, Pseudomonas Aeruginosa Infection
10/25
12/25
NCT05622890: A Single-arm Clinical Trial of IMGN853 in Chinese Adult Patients With Platinum-resistant, Epithelial Ovarian Cancer

Recruiting
3
35
RoW
Mirvetuximab Soravtansine, IMGN853, MIRV
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Epithelial Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
04/23
12/23
NCT06697522: Study of Atropine Sulfate Eye Drops(0.01%) in Treating Near-work-induced Transient Myopia in Children

Completed
3
148
RoW
Atropine Sulfate, Investigational product, Placebo, Blank Solvent
Ocumension Therapeutics (Suzhou) Co., Ltd, Beijing Children's Hospital
Myopia
10/23
03/24
NCT05793892: Efficacy and Safety of Lidocaine and Tetracaine Cream for Facial Laser Aesthetics in Chinese Adults

Completed
3
286
RoW
Lidocaine tetracaine cream, test drug:CU-30101, control drug:Pliaglis
Cutia Therapeutics（Wuxi）Co.,Ltd
Analgesia
08/23
10/23
QWINT-2, NCT05362058: A Study of Insulin Efsitora Alfa (LY3209590) Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time

Completed
3
928
Europe, Canada, Japan, US, RoW
Insulin Efsitora Alfa, LY3209590 and Basal Insulin-FC, Insulin Degludec
Eli Lilly and Company
Diabetes, Type 2 Diabetes
04/24
04/24
ATTAIN-OSA, NCT06649045: A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or Overweight

Recruiting
3
600
Europe, Japan, US, RoW
Orforglipron, LY3502970, Placebo
Eli Lilly and Company
OSA, Overweight or Obesity
11/26
01/27
NCT06717152: Efficacy and Safety of SJP-0132 Eye Drops in Chinese Patients With Dry Eye Disease

Recruiting
3
400
RoW
SJP-0132, Placebo
Senju Pharmaceutical Science & Technology (Beijing) Co., Ltd., Senju Pharmaceutical Co., Ltd.
Dry Eye
07/25
08/25
ATTAIN-1, NCT05869903: A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

Active, not recruiting
3
3000
Europe, Japan, US, RoW
Orforglipron, LY3502970, Placebo
Eli Lilly and Company
Obesity, Overweight, Overweight or Obesity
07/25
07/27
TRIUMPH-1, NCT05929066: A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight

Active, not recruiting
3
2300
Europe, Canada, US, RoW
Retatrutide, LY3437943, Placebo
Eli Lilly and Company
Obesity, Overweight, Osteoarthritis, Knee, Obstructive Sleep Apnea
04/26
05/26
Keypoint-1, NCT05302011: Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma

Completed
2
28
RoW
Pembrolizumab, Carboplatin or Cisplatin, chemotherapy, Docetaxel
Peking Union Medical College Hospital
Esophageal Squamous Cell Carcinoma
03/23
06/23
NCT06161272: Fluzoparib With or Without Apatinib in Platinum-sensitive Relapsed Ovarian Cancer Previously Treated With PARPi

Not yet recruiting
2
80
RoW
Fluzoparib, Fluzoparib+Apatinib
Guangxi Medical University
Ovarian Cancer, High Grade Serous Adenocarcinoma of Ovary, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
03/25
01/26
NCT06176235: Teriflunomide Plus High-dose Dexamethasone as First-line Treatment in Newly Diagnosed Primary Immune Thrombocytopenia

Recruiting
2
132
RoW
Teriflunomide, AUBAGIO, Dexamethasone
Peking University People's Hospital, Beijing Luhe Hospital, Chinese PLA General Hospital, Navy General Hospital, Beijing, Beijing Hospital, Beijing Friendship Hospital, Peking University First Hospital, Peking University Third Hospital, China-Japan Friendship Hospital, Beijing Tsinghua Changgeng Hospital
Immune Thrombocytopenia
12/24
05/25
NCT05932524: Low-dose Baricitinib Plus High-dose Dexamethasone for Patients With Newly Diagnosed Immune Thrombocytopenia

Recruiting
2
132
RoW
Baricitinib 2 MG, Olumiant, Dexamethasone, HD-DXM
Peking University People's Hospital, Beijing Luhe Hospital, Chinese PLA General Hospital, Navy General Hospital, Beijing, Beijing Hospital, Beijing Friendship Hospital, Peking University First Hospital, Peking University Third Hospital, China-Japan Friendship Hospital, Beijing Tsinghua Changgeng Hospital
Immune Thrombocytopenia
06/24
06/25
NCT05852847: Low-dose Baricitinib Plus Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia

Recruiting
2
216
RoW
Baricitinib 2 MG [Olumiant], Olumiant, Danazol
Peking University People's Hospital, Beijing Luhe Hospital, Chinese PLA General Hospital, Navy General Hospital, Beijing, Beijing Hospital, Beijing Friendship Hospital, Peking University First Hospital, Peking University Third Hospital, China-Japan Friendship Hospital, Beijing Tsinghua Changgeng Hospital
Immune Thrombocytopenia
11/24
05/25
CRTOG2401, NCT06714708: Low Dose Radiotherapy Combined With Sintilimab and Chemotherapy as Neoadjuvant Therapy for Stage II-III NSCLC

Recruiting
2
86
RoW
Experimental, Active comparator
Anhui Provincial Cancer Hospital
NSCLC, Neoadjuvant Immunotherapy, Low Dose Radiotherapy, Sintilimab
12/26
06/27
JSKN003-102, NCT05744427: Safety and Tolerability of JSKN003 in Chinese Subjects With Advanced Solid Tumors

Hourglass Dec 2024 - Dec 2024 : Results for HER2-low, U/M BC
Recruiting
1/2
725
RoW
JSKN003
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
Advanced Solid Tumor
12/24
12/26
NCT06593093: A Bundled Intervention

Not yet recruiting
1/2
190
US
a bundled intervention, control group
University of Alabama at Birmingham, National Institute on Drug Abuse (NIDA)
Opioid Use Disorder, Opioid Overdose
11/30
11/30
OPAL-1, NCT05970497: A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

Recruiting
1/2
240
US
KB707, Opdualag, KEYTRUDA ®( Pembrolizumab)
Krystal Biotech, Inc.
Cancer, Melanoma Stage III, Melanoma Stage IV, Cutaneous Melanoma
07/27
07/27
NCT04977193: A Study to Evaluate the Safety and Efficacy of ly011 Cell Injection in the Treatment of Advanced Gastric Adenocarcinoma

Recruiting
1
18
RoW
LY011
Shanghai Longyao Biotechnology Inc., Ltd., The Affiliated Hospital of Xuzhou Medical University
Advanced Gastric Adenocarcinoma
05/23
11/24
TQB2858-Ⅰ-06, NCT05068921: A Clinical Trial to Evaluate Tolerability and Pharmacokinetics of TQB2858 Injection in Subjects With Advanced Malignancy

Recruiting
1
40
RoW
TQB2858 injection
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Advanced Cervical Cancer
05/23
07/23
NCT06678581: SAD,MAD and Food Effect Study of SAP-001 Tablets in Chinese Subjects

Completed
1
70
RoW
SAP-001, SAP-001 tablet, Placebo, placebo tablet
Shanton Pharma Co., Ltd.
Gout, Hyperuricemia
12/23
01/24
DEVIF-I, NCT06230822: Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Recruiting
1
9
RoW
VUM02 Injection, Human Umbilical Cord Tissue-derived Mesenchymal Stem Cells Injection
Wuhan Optics Valley Vcanbiopharma Co., Ltd.
Idiopathic Pulmonary Fibrosis
01/25
12/26
OASIS, NCT06063317: A Study of OnCARlytics (CF33-CD19) in Combination with Blinatumomab in Adults with Advanced or Metastatic Solid Tumors

Recruiting
1
33
US
CF33-CD19 IT, CF33-CD19 IV, Blinatumomab, Blincyto
Imugene Limited
Solid Tumor, Adult
06/27
05/29
NCT06104241: BGT007 Cells for the Treatment of Refractory Digestive System Tumors

Recruiting
1
14
RoW
BGT007 Injection
The Affiliated Hospital of Xuzhou Medical University, Guangzhou Bioresette Biomedical Technology Co., Ltd.
Gastrointestinal Cancer
10/26
10/27
NCT06104215: BGT007H Cells for the Treatment of Refractory Digestive System Tumors

Recruiting
1
14
RoW
BGT007H Injection
The Affiliated Hospital of Xuzhou Medical University, Guangzhou Bioresette Biomedical Technology Co., Ltd.
Digestive Tract Cancer
10/26
10/27
Solitaire, NCT04692402: Feasibility Trial Evaluating Efficacy and Safety of â„¢ Thrombus Retrieval Device in the Management of Refractory Thrombus in Patients With Acute Coronary Syndrome

Recruiting
N/A
51
RoW
Solitaireâ„¢ thrombus retrieval device
Paul Ong
Refractory Thrombus in Patients With Acute Coronary Syndrome
06/22
09/22
NCT05469152: Detachable String Magnetically Controlled Capsule Endoscopy for Follow-up of Patients With Esophageal Diseases

Recruiting
N/A
310
RoW
ds-MCE and EGD
Changhai Hospital, Ruijin Hospital, Shanghai Zhongshan Hospital, XuHui District Central Hospital, Yangpu District Central Hospital Affiliated to Tongji University, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 6th People's Hospital
Esophageal Diseases
09/22
09/22
NCT05273840: Effect of Nutritional Supplements on Clinical Outcomes in Patients With Prediabetes and Obesity

Recruiting
N/A
100
RoW
Ivital Control, Produced by Fresenius Kabi, Chocolate flavor, Product specifications: 460g (46g*10), lifestyle intervention
Ningbo No. 1 Hospital
PreDiabetes, Obesity
10/22
11/22
NCT03748563: Accuracy of Magnetically Maneuvered Capsule Endoscopy for Detection of EGV in Patients With Cirrhosis

Completed
N/A
607
RoW
ds-MCE and EGD
Changhai Hospital, Ruijin Hospital, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai East Hospital of Tongji University, Yangpu District Central Hospital Affiliated to Tongji University, Zhujiang Hospital, Qilu Hospital of Shandong University, The Third Xiangya Hospital of Central South University, First Affiliated Hospital Xi'an Jiaotong University, Wuhan Union Hospital, China, The Fifth Affiliated Hospital of Zunyi Medical College, The First Affiliated Hospital of Zhejiang Chinese Medical University, Shanghai Pudong New Area Gongli Hospital
Liver Cirrhosis, Portal Hypertension, Esophageal Varices, Gastric Varix
01/23
03/23
NCT05561855: T2DM Intensity Lifestyle Intervention

Completed
N/A
120
RoW
lifestyle intervention
Ningbo No. 1 Hospital, Peking University
Diabetes Mellitus, Type 2, Overweight or Obesity
06/23
07/23
NCT06493669: Study on the Correlation Between Treg Immune Cells on the Muscle Content and Cognitive Functions of the Elderly

Recruiting
N/A
100
RoW
Cognitive assessment
Fifth Affiliated Hospital, Sun Yat-Sen University
Cognitive Disorder Patients and Cognitive Assessment
12/24
12/24
NCT06371313: Endocrine, Metabolic and Inflammatory Characteristics of Offspring of Mothers With PCOS Hyperandrogenism

Completed
N/A
42
RoW
Guangdong Women and Children Hospital
PCOS
03/24
03/24
NCT05389254: Association Between Time in Range and In-hospital Outcomes in Type 2 Diabetic Patients With Acute Coronary Syndrome

Not yet recruiting
N/A
100
RoW
continuous glucose monitoring system, capillary blood glucose monitoring
Ningbo No. 1 Hospital
Type 2 Diabetes Mellitus, Acute Coronary Syndrome
06/23
12/23
ARM-SI-ALI, NCT04541264: Radiomics Markers to Predict Sepsis Induced Acute Respiratory Distress Syndrome

Recruiting
N/A
300
RoW
radiomic of chest CT
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Early Prediction for Sepsis Induced Acute Lung Injury
08/23
12/23
NCT05455099: A Multicenter Study of Ultrafast Pulse Wave Velocity in Obese Chinese Han Adults

Recruiting
N/A
2400
RoW
Carotid ultrasound examination 1, Carotid ultrasound examination 2
First Hospital of China Medical University
Carotid Artery Diseases
08/23
07/24
NCT05516641: Prebiotics in Rectal Cancer

Recruiting
N/A
20
US
Soluble Corn Fiber, Maltodextrin
Ochsner Health System
Rectal Cancer
12/23
07/24
NCT05482191: Healthy Weight Management Project for Overweight and Obesity Children

Active, not recruiting
N/A
300
RoW
Lifestyle intervention
Ningbo No. 1 Hospital, Peking University
Obesity
12/23
12/25
NCT05482165: Optimizing Intervention Effects in Children and Adolescents

Active, not recruiting
N/A
1800
RoW
Multi-faceted health promotion programme
Ningbo No. 1 Hospital, Peking University
Childhood Obesity
12/23
12/25
NCT05872425: Efficacy and Safety of Dingkundan Combined With Combination Oral Contraceptives in the Treatment of PCOS

Completed
N/A
120
RoW
DingKunDan(GuangYuYuan), DingKunDan(GuangYuYuan): Z20059003, Drospirenone and Ethinylestradiol Tablets (Ⅱ): H20140972, Drospirenone and Ethinylestradiol Tablets (Ⅱ)
Guangdong Women and Children Hospital
PCOS
04/24
04/24
NCT06256848: Effect of Myofascial Release on Dysphagia in Stroke Survivors

Recruiting
N/A
80
RoW
Rehabilitation treatment, Myofascial Release Therapy
Zeng Changhao, People's Hospital of Zhengzhou University
Dysphagia
05/24
05/24
NCT06249516: Effect of Active Breathing Exercises in Stroke Patients With Respiratory Rhythm Disorder

Not yet recruiting
N/A
80
RoW
Rehabilitation training, Active Breathing Exercises
Zeng Changhao, People's Hospital of Zhengzhou University
Respiratory Rhythm Disorder
06/24
06/24
NCT06427018: Expressions of Ezrin and Pip5k1α Proteins in Airway Smooth Muscle of Asthmatic Patients

Recruiting
N/A
60
RoW
No intervention.
Lei-Miao Yin, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 6th People's Hospital, Xiangya Hospital of Central South University, Baoshan Hospital, Shanghai University of Traditional Chinese Medicine
Asthma, Protein
06/25
12/25
 

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