| Marshall, Gailen D |
| Completed | 3 | 397 | Europe, Canada, Japan, US, RoW | GSK3511294 (Depemokimab), Placebo | GlaxoSmithKline, Iqvia Pty Ltd | Asthma | 04/24 | 04/24 | | |
| Recruiting | 3 | 1700 | Europe, Canada, Japan, US, RoW | GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS) | GlaxoSmithKline, Iqvia Pty Ltd | Asthma | 09/25 | 09/25 | | |
|
| Recruiting | 2 | 380 | US | IVIG + Coordinated Care, IVIG Placebo + Coordinated Care, Ivabradine + Coordinated Care, Ivabradine Placebo + Coordinated Care, IVIG + Usual Care, IVIG Placebo + Usual Care, Ivabradine + Usual Care, Ivabradine Placebo + Usual Care | Kanecia Obie Zimmerman | Long COVID, Long Covid19, Long Covid-19 | 12/25 | 03/26 | | |
| Recruiting | 2 | 900 | US | Experimental: Paxlovid 25 day dosing, Experimental: Paxlovid 15 day dosing, Placebo Comparator: Control | Kanecia Obie Zimmerman | Long COVID, Long Covid19 | 07/25 | 10/25 | | |
| Completed | 1 | 86 | US | COVID Convalescent Plasma, CCP, COVID-19 Convalescent Plasma | Gailen D. Marshall Jr., MD PhD, University of Mississippi Medical Center | COVID-19 | 03/23 | 03/23 | | |
NCT05556967: Identification of Surrogate Blood and/or Urine Biomarker for Immulina TM (Trademark) in Normal Humans |
|
|
| Completed | N/A | 20 | US | Immulina, Spirulina | University of Mississippi Medical Center, University of Mississippi National Center for Natural Products Research, National Center for Complementary and Integrative Health (NCCIH) | Adherence, Patient | 10/23 | 10/23 | | |
NCT05172024: Understanding the Long-term Impact of COVID-19 in Adults (RECOVER) |
|
|
| Recruiting | N/A | 14880 | US | | NYU Langone Health, National Heart, Lung, and Blood Institute (NHLBI) | SARS-CoV2 Infection | 04/25 | 05/25 | | |
NCT05447078: Spirulina Oral Supplement for Enhancing Host Resilience to Virus Infection |
|
|
| Recruiting | N/A | 472 | US | Immulina TM, Spirulina, Placebo | University of Mississippi Medical Center, National Center for Complementary and Integrative Health (NCCIH) | Healthy Volunteers | 12/25 | 06/26 | | |
| Active, not recruiting | N/A | 718 | Europe, Canada, Japan, US | DUPIXENT®, dupilumab, REGN668, SAR231893 | Regeneron Pharmaceuticals, Sanofi | Asthma | 07/26 | 07/26 | | |
| Harbrecht, Brian G |
TOWAR, NCT04684719: Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial |
|
|
| Recruiting | 3 | 1020 | US | low titer whole blood, Standard Care | Jason Sperry, United States Department of Defense | Hemorrhagic Shock, Traumatic Injury | 07/25 | 09/25 | | |
| Recruiting | N/A | 2009 | US | Supraglottic airway device, LMA, King, igel, Standard airway management | Jason Sperry, United States Department of Defense | Trauma Injury, Airway Control | 03/25 | 03/26 | | |
| Contact, Central |
NCT03641560: A Safety and Efficacy Study of Enzalutamide in Indian Patients With Progressive Metastatic Castration-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel-Based Chemotherapy |
|
|
| Completed | 4 | 52 | RoW | Enzalutamide, MDV3100, Xtandi, Androgen deprivation therapy (ADT) | Astellas Pharma Inc | Metastatic Castration Resistant Prostate Cancer | 02/24 | 02/24 | | |
NCT02294461: An Asian Study to Evaluate Efficacy and Safety of Oral Enzalutamide in Progressive Metastatic Prostate Cancer Participants |
|
|
| Active, not recruiting | 3 | 395 | RoW | Enzalutamide, Xtandi, MDV3100, Placebo | Astellas Pharma Inc | Progressive Metastatic Prostate Cancer | 09/15 | 06/24 | | |
TAP, NCT05568888: Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( Study ) |
|
|
| Recruiting | 3 | 8000 | Europe, US, RoW | BE1116, 4-Factor Prothrombin Complex, Kcentra®, Beriplex®, Placebo | CSL Behring | Traumatic Injury | 09/26 | 09/26 | | |
NCT02439268: The Safety and Efficacy Study of Vemurafenib (CT) Compared With Vemurafenib (Zelbolaf®) in Advanced Patients Harboring the V600 BRAF Mutation |
|
|
| Active, not recruiting | 2 | 100 | RoW | Vemurafenib, Zelboraf, Vemurafenib (CT), RO5185426, PLX4032 | Cancer Centre of Monoclonal Therapy, LLC, The European Association for Cancer Research, Melanoma Research Foundation, Alliance for Clinical Trials in Oncology in EU | Colorectal Cancer, Recurrent/Refractory BRAFV600E-mutant Gliomas, Advanced Cancers, Melanoma, Advanced BRAF-mutant Cancers | 07/15 | 05/18 | | |
NCT02430220: The Safety and Efficacy Study of Regorafenib (CT) Compared With Regorafenib (STIVARGA) in Patients With Solid Tumors |
|
|
| Active, not recruiting | 2 | 152 | RoW | Regorafenib (CT), BAY 73-4506, Regorafenib (STIVARGA) | Cancer Centre of Monoclonal Therapy, LLC, Clinical Cancer Hospital, Bayer | Solid Tumors, Colorectal Cancer | 04/18 | 09/18 | | |
| Active, not recruiting | 2 | 100 | US | ALG-055009, Placebo | Aligos Therapeutics | NASH, MASH, Metabolic Dysfunction-Associated Steatohepatitis, Nonalcoholic Steatohepatitis | 11/24 | 12/24 | | |
PRL-02-1001, NCT04729114: Open-label, Multicenter Study of Intramuscular PRL-02 Depot in Patients With Advanced Prostate Cancer |
|
|
| Recruiting | 1/2 | 100 | US | PRL-02 injection, prednisone, dexamethasone, docetaxel infusion | Astellas Pharma Global Development, Inc. | Prostate Cancer, mCRPC, mCSPC | 12/24 | 04/25 | | |
NCT06285214: Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome |
|
|
| Recruiting | 1 | 44 | US | V117957, Placebo | Imbrium Therapeutics, Purdue Pharma LP | Interstitial Cystitis/Bladder Pain Syndrome | 06/26 | 06/26 | | |
NCT04285827: Safety of Single Doses of CSL889 in Adult Patients With Sickle Cell Disease |
|
|
| Completed | 1 | 28 | Europe, US | CSL889 | CSL Behring | Sickle Cell Disease | 07/23 | 07/23 | | |
NCT03426254: Comparison of Safety and Clinical Benefit of Injections Subcutaneously Talazoparib Versus Oral Talazoparib in Patients With Solid Tumors |
|
|
| Withdrawn | 1 | 10 | RoW | Injections Subcutaneously Talazoparib, MDV3800, BMN673, Oral capsules Talazoparib | Center Trials & Treatment, BioGene Pharmaceutical | Advanced or Recurrent Solid Tumors, Breast Neoplasm | 12/23 | 01/24 | | |
|
NCT06364696: A Study to Find a Suitable Dose of ASP4396 in Adults With Solid Tumors |
|
|
| Recruiting | 1 | 175 | US | ASP4396 | Astellas Pharma Inc | Solid Tumor | 04/27 | 04/27 | | |
NCT06248086: A Study to Find a Suitable Dose of ASP2802 in People With CD20-positive B-cell Lymphomas |
|
|
| Recruiting | 1 | 21 | RoW | ASP2802, MACT, MA-20, ASP101G, MicAbody | Astellas Pharma Global Development, Inc. | B-cell Lymphoma | 06/26 | 08/31 | | |
| Recruiting | 1 | 229 | US | ASP1012, Pembrolizumab | Astellas Pharma Global Development, Inc. | Solid Tumor | 06/29 | 06/29 | | |
NCT06024642: Study of V117957 in Overactive Bladder Syndrome |
|
|
| Completed | 1 | 51 | US | V117957, Placebo | Imbrium Therapeutics, Purdue Pharma LP | Overactive Bladder Syndrome | 05/24 | 05/24 | | |
| Completed | N/A | 1332 | US | | Shire | Hunter Syndrome | 02/23 | 02/23 | | |
NCT05104840: A Randomized Study to Determine the Expression of the Furin Protein in Patients With SARS-CoV-2 and Vaccinated Against Coronavirus |
|
|
| Terminated | N/A | 2432 | US, RoW | | Center Trials & Treatment, Oleg Martynenko | COVID-19, SARS-CoV-2, Furin, RGMc Processing, Paired Basic Amino Acid Cleaving Enzyme (PACE) | 03/23 | 03/23 | | |
| Recruiting | N/A | 1257 | US | | Shire | Gaucher Disease | 01/25 | 01/25 | | |
OPTION-VMS, NCT06049797: A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats |
|
|
| Recruiting | N/A | 1000 | US | Fezolinetant, ESN364, VEOZAH, Paroxetine, Citalopram, Escitalopram, Desvenlafaxine, Venlafaxine, Gabapentin, Clonidine, Pregabalin, Oxybutynin, Any other SSRI/SNRI not already specified, Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above | Astellas Pharma Global Development, Inc. | Hot Flashes | 02/26 | 11/26 | | |
NCT03971253: Japan Post-Marketing Surveillance for Peficitinib to Assess Safety and Effectiveness in the Patients With Rheumatoid Arthritis |
|
|
| Recruiting | N/A | 3000 | Japan | Peficitinib, ASP015K, Smyraf | Astellas Pharma Inc | Rheumatoid Arthritis (RA) | 12/25 | 12/25 | | |
NCT05886348: The Evaluation of Safety and Myopia Progression Control Using Novel Spectacle Lens |
|
|
| Active, not recruiting | N/A | 249 | RoW | Model-A Novel spectacle lens, Model-B Novel spectacle lens, Single vision spectacle lens | HOYA Lens Thailand LTD. | Myopia | 05/26 | 05/27 | | |
NCT06011954: A Study to Survey Adults in South Korea With Cancer Who Receive PADCEV Injection |
|
|
| Recruiting | N/A | 235 | RoW | Enfortumab Vedotin, PADCEV, ASG-22CE | Astellas Pharma Korea, Inc., Seagen Inc. | Urothelial Cancer | 07/27 | 07/27 | | |
| Recruiting | N/A | 350 | US | Veye Lung nodules | Aidence | Lung; Node | 07/21 | 07/21 | | |
| Kutcher, Matthew |
| Active, not recruiting | 4 | 3239 | Europe, US, RoW | theraputic heparin, unfractionated heparin, Enoxaparin, Dalteparin, Tinzaparin, Heparin, prophylactic heparin, enoxaparin, dalteparin, Fondparinux, P2Y12, Ticagrelor, Prasugrel, Clopidogrel, Crizanlizumab Injection, SGLT2 inhibitor, dapagliflozin, empagliflozin, canagliflozin, ertugliflozin | Matthew Neal MD, National Heart, Lung, and Blood Institute (NHLBI) | Covid19 | 08/23 | 06/24 | | |
TOWAR, NCT04684719: Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial |
|
|
| Recruiting | 3 | 1020 | US | low titer whole blood, Standard Care | Jason Sperry, United States Department of Defense | Hemorrhagic Shock, Traumatic Injury | 07/25 | 09/25 | | |
| Completed | 2 | 200 | US | Cold Stored Platelets (CSP), Standard Care | Jason Sperry, United States Department of Defense | Trauma, Hemorrhage | 10/23 | 11/23 | | |
