| Reyzelman, Alexander |
NCT03754465: Clinical Study of ALLO-ASC-SHEET in Subjects With Diabetic Foot Ulcers |
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| Active, not recruiting | 2 | 56 | US | ALLO-ASC-DFU, Hydrogel sheet containing Allogenic Mesenchymal Stem Cells, Hydrogel SHEET(Vehicle control), Hydrogel sheet without Allogenic Mesenchymal Stem Cells | Anterogen Co., Ltd. | Diabetic Foot Ulcer | 11/23 | 05/24 | | |
PL-5, NCT06189638: Phase II Study to Evaluate Efficacy and Safety of AMP Peptide in Mild Infections of Diabetic Foot Ulcers |
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| Active, not recruiting | 2 | 90 | US | Antimicrobial Peptide PL-5 Topical Spray and Placebo, AMP PL-5 and Placebo | Jiangsu ProteLight Pharmaceutical & Biotechnology Co., Ltd., Parexel | Diabetic Foot Ulcers | 12/26 | 12/27 | | |
EnEPC-CLI, NCT02805023: BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI) |
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| Recruiting | 1/2 | 50 | US, RoW | BGC101 (autologous EnEPC preparation), Control medium | BioGenCell Ltd., Laniado Hospital, Rabin Medical Center | Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease | 12/27 | 12/27 | | |
NCT05494450: An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds |
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| Terminated | N/A | 46 | US | ExufiberAG+ | Molnlycke Health Care AB | Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer | 11/22 | 11/22 | | |
NCT05608317: A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam Dressing |
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| Recruiting | N/A | 20 | US | ALLEVYN Non-Adhesive | Molnlycke Health Care AB | Wounds, Wound of Skin, Wound Leg, Venous Leg Ulcer | 07/24 | 11/24 | | |
NCT04564443: A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot |
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| Active, not recruiting | N/A | 222 | US | Medaxis Debritom+, Sharp Surgical Debridement, Additional Outer Dressing Application, Offloading, Pressure Relief, Fibracol Wound Dressing, Calcium Alginate | Medaxis, LLC, Professional Education and Research Institute | Diabetic Foot Ulcer, Diabetic Foot | 12/24 | 12/24 | | |
NCT05588583: A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing. |
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| Recruiting | N/A | 68 | US | Mepilex Up | Molnlycke Health Care AB | Wounds, Wound of Skin, Wound Leg, Wound; Foot, Diabetic Foot Ulcer, Venous Leg Ulcer | 03/24 | 03/24 | | |
Mavericks, NCT05758545: Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers |
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| Recruiting | N/A | 450 | US | COMS One device, Concurrent Optical and Magnetic Stimulation, Sham device | Piomic Medical, NAMSA | Diabetic Foot Ulcer | 06/27 | 06/27 | | |
| Garcia, Jose Luis |
NCT05894577: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm F (Montelukast) |
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| Completed | 3 | 1453 | US | Placebo, Montelukast | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 07/23 | 01/24 | | |
NCT04885530: ACTIV-6: COVID-19 Study of Repurposed Medications |
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| Completed | 3 | 10956 | US | Ivermectin, Ivermectin Tablets, Fluvoxamine, Fluvoxamine Maleate Tablets, Fluticasone, Fluticasone Furoate, Placebo, Montelukast, Metformin | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 04/24 | 04/24 | | |
NCT06042855: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin) |
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| Completed | 3 | 3214 | US | Placebo, Metformin | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 06/24 | 11/24 | | |
NCT06261957: A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants ≥ 18 Years of Age With Asthma |
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| Recruiting | 3 | 412 | Europe, Canada, US, RoW | Salbutamol HFA-134a, Salbutamol HFA-152a | GlaxoSmithKline | Asthma | 04/25 | 04/25 | | |
| Completed | 3 | 806 | Europe, Canada, US, RoW | Placebo, Mepolizumab | GlaxoSmithKline, PPD DEVELOPMENT, LP | Pulmonary Disease, Chronic Obstructive | 08/24 | 08/24 | | |
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GRIT, NCT04867317: Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD) |
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| Recruiting | 3 | 172 | US | Somatropin, Placebo | VA Office of Research and Development | Adult Growth Hormone Deficiency, Mild Traumatic Brain Injury | 03/26 | 03/28 | | |
| Completed | 2 | 203 | Europe, US, RoW | Olorofim, F901318 | F2G Biotech GmbH, Iqvia Pty Ltd | Invasive Fungal Infections | 02/23 | 02/23 | | |
NCT05312567: FP-101 Versus Placebo in the Treatment of Menopausal Vasomotor Symptoms |
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| Completed | 2 | 105 | US | FP-101 | Fervent Pharmaceuticals, ICON plc | Vasomotor Symptoms, Menopause | 04/23 | 07/23 | | |
| Completed | 2 | 39 | Europe, US, RoW | RGH-706, Placebo | Gedeon Richter Plc., Gedeon Richter Plc, Chemical Works of Gedeon Richter Plc | Prader-Willi Syndrome | 04/24 | 04/24 | | |
| Recruiting | 2 | 20 | US | Recombinant human growth hormone, Somatropin, Genotropin, Humatrope, Norditropin | Baylor College of Medicine, United States Department of Defense | Gulf War Syndrome, Adult Growth Hormone Deficiency | 05/25 | 09/25 | | |
TEMEC, NCT04301765: Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency |
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| Recruiting | 2 | 230 | US | testosterone 1.62% gel, placebo gel | Seattle Institute for Biomedical and Clinical Research | Hypogonadism, Male, Cancer, Fatigue | 01/26 | 01/26 | | |
NCT04049331: Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone |
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| Recruiting | 2 | 240 | US | Testosterone Undecanoate 750 MG/3 ML Intramuscular Solution [AVEED], study drug, placebo | Seattle Institute for Biomedical and Clinical Research | Hypogonadism, Male, Fatigue Syndrome, Chronic | 01/26 | 01/26 | | |
| Terminated | 1/2 | 102 | Europe, US | Tazemetostat, EPZ-6438, E7438, IPN60200, Abiraterone/prednisone, Zytiga, Enzalutamide, Xtandi | Epizyme, Inc. | Metastatic Prostate Cancer, Metastatic Castration-resistant Prostate Cancer | 11/24 | 11/24 | | |
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| Terminated | N/A | 32 | Europe | dPR and FFR | Opsens, Inc. | Aortic Stenosis | 03/23 | 04/23 | | |
NCT03867357: Intramuscular Mechanisms of Androgen Deprivation-related Sarcopenia |
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| Completed | N/A | 60 | US | GnRH agonist, Zoladex, Goserelin | Seattle Institute for Biomedical and Clinical Research, United States Department of Defense, University of Washington | Metastatic Prostate Cancer, Androgen Deprivation Therapy | 09/23 | 09/23 | | |
Mavericks, NCT05758545: Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers |
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| Recruiting | N/A | 450 | US | COMS One device, Concurrent Optical and Magnetic Stimulation, Sham device | Piomic Medical, NAMSA | Diabetic Foot Ulcer | 06/27 | 06/27 | | |
NCT04364256: Muscle Stimulation for Physical Function During Stem Cell Transplant |
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| Recruiting | N/A | 46 | US | RS-4i Plus Sequential Stimulator (RS Medical, Vancouver, WA), NMES, e-stim | VA Office of Research and Development | Autologous Hematopoietic Stem Cell Transplant | 12/25 | 05/26 | | |
| Rowe, Vincent |
Mavericks, NCT05758545: Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers |
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| Recruiting | N/A | 450 | US | COMS One device, Concurrent Optical and Magnetic Stimulation, Sham device | Piomic Medical, NAMSA | Diabetic Foot Ulcer | 06/27 | 06/27 | | |
| Peralta, Maria |
NCT04176120: Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU) |
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| Completed | 3 | 220 | US | TTAX01, Standard Care | Tissue Tech Inc. | Diabetic Foot Infection, Non-healing Wound, Non-healing Diabetic Foot Ulcer | 01/24 | 06/24 | | |
NCT04667416: Safety and Preliminary Efficacy of PalinGen Flow Amniotic Tissue Allograft in Chronic Ulcers of the Lower Extremities |
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| Active, not recruiting | 2 | 82 | US | PalinGen Flow Amniotic Tissue Allograft | Amnio Technology, LLC | Chronic Ulcer of Lower Extremity | 03/24 | 01/25 | | |
NCT04564443: A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot |
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| Active, not recruiting | N/A | 222 | US | Medaxis Debritom+, Sharp Surgical Debridement, Additional Outer Dressing Application, Offloading, Pressure Relief, Fibracol Wound Dressing, Calcium Alginate | Medaxis, LLC, Professional Education and Research Institute | Diabetic Foot Ulcer, Diabetic Foot | 12/24 | 12/24 | | |
NCT06035536: Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers |
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| Recruiting | N/A | 120 | US | Symphony™ plus Off-loading, Wound Dressing comprising of calcium alginate Fibracol | Aroa Biosurgery Limited, Professional Education and Research Institute | Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Chronic Foot Ulcer | 12/24 | 12/24 | | |
Mavericks, NCT05758545: Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers |
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| Recruiting | N/A | 450 | US | COMS One device, Concurrent Optical and Magnetic Stimulation, Sham device | Piomic Medical, NAMSA | Diabetic Foot Ulcer | 06/27 | 06/27 | | |
| Fortt, Tabitha |
NCT05894577: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm F (Montelukast) |
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| Completed | 3 | 1453 | US | Placebo, Montelukast | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 07/23 | 01/24 | | |
NCT04885530: ACTIV-6: COVID-19 Study of Repurposed Medications |
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| Completed | 3 | 10956 | US | Ivermectin, Ivermectin Tablets, Fluvoxamine, Fluvoxamine Maleate Tablets, Fluticasone, Fluticasone Furoate, Placebo, Montelukast, Metformin | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 04/24 | 04/24 | | |
NCT06042855: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin) |
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| Completed | 3 | 3214 | US | Placebo, Metformin | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 06/24 | 11/24 | | |
| Achong, Angel |
CHANGE AFIB, NCT05130268: Early Dronedarone Versus Usual Care to Improve Outcomes in Persons With Newly Diagnosed Atrial Fibrillation |
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| Completed | 4 | 339 | US | Dronedarone, Multaq | American Heart Association, Duke Clinical Research Institute, Sanofi | Atrial Fibrillation | 01/24 | 06/24 | | |
NCT05894577: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm F (Montelukast) |
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| Completed | 3 | 1453 | US | Placebo, Montelukast | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 07/23 | 01/24 | | |
NCT04885530: ACTIV-6: COVID-19 Study of Repurposed Medications |
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| Completed | 3 | 10956 | US | Ivermectin, Ivermectin Tablets, Fluvoxamine, Fluvoxamine Maleate Tablets, Fluticasone, Fluticasone Furoate, Placebo, Montelukast, Metformin | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 04/24 | 04/24 | | |
NCT06042855: ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin) |
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| Completed | 3 | 3214 | US | Placebo, Metformin | Susanna Naggie, MD, National Center for Advancing Translational Sciences (NCATS), Vanderbilt University Medical Center | Covid19 | 06/24 | 11/24 | | |
NCT05805046: Study of Avelle™ Negative Pressure Wound Therapy (NPWT) System |
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| Withdrawn | N/A | 59 | US | Negative Pressure Wound Therapy System, Avelle™ Negative Pressure Wound Therapy System | ConvaTec Inc. | Surgical Wound, Recent, Surgical Wound Leak, Dehiscence Wound, Trauma-related Wound | 10/23 | 10/23 | | |
NCT05590715: International Multicentric Observational Study to Characterize Subpopulations of Patients with Autism Spectrum Disorder |
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| Recruiting | N/A | 1500 | Europe, US, RoW | | Stalicla SA | Autism Spectrum Disorder | 12/25 | 12/25 | | |
Mavericks, NCT05758545: Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers |
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| Recruiting | N/A | 450 | US | COMS One device, Concurrent Optical and Magnetic Stimulation, Sham device | Piomic Medical, NAMSA | Diabetic Foot Ulcer | 06/27 | 06/27 | | |
| Garcia, Mari |
NCT05543707: PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19 |
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| Terminated | 2 | 242 | US | PBI-0451 (Pomotrelvir), Active, Placebo | Pardes Biosciences, Inc. | COVID-19 | 01/23 | 04/23 | | |
Mavericks, NCT05758545: Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers |
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| Recruiting | N/A | 450 | US | COMS One device, Concurrent Optical and Magnetic Stimulation, Sham device | Piomic Medical, NAMSA | Diabetic Foot Ulcer | 06/27 | 06/27 | | |
