| Enrolling by invitation | N/A | 1000 | Europe | Open surgery, Laparoscopic surgery, Robotic surgery, taTME | Hospital Central de la Defensa Gómez Ulla, Clinica Universidad de Navarra, Universidad de Navarra | PROM, Rectal Cancer, Functional Bowel Disorder | 12/25 | 12/27 | | |
| Recruiting | N/A | 200 | Europe | Open Total Mesorectal Excision, Laparoscopic Total Mesorectal Excision, Robotic Total Mesorectal Excision, Transanal Total Mesorectal Excision | University Hospital Gregorio Marañón, University of Navarrra Hospital (Clinica Universitaria), Hospital de Leon, Hospital del Río Hortega | Sphincter Ani Incontinence, Rectal Cancer | 09/25 | 09/28 | | |
| Recruiting | N/A | 300 | Europe, RoW | | Bordeaux Colorectal Institute Academy | Colorectal Surgery, Benign or Malignant Rectal or Colon Tumors | 01/27 | 01/27 | | |