| Perrotin, Franck |
| Terminated | 3 | 429 | Europe, RoW | Balloon catheter + oral misoprostol, Oral misoprostol alone | University Hospital, Toulouse | Maternal Obesity | 02/23 | 02/23 | | |
APPART, NCT05625724: Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology |
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| Recruiting | 3 | 1164 | Europe | Aspirin, Placebo | University Hospital, Toulouse | ART, Pre-Eclampsia | 05/25 | 05/26 | | |
PREGRALL, NCT03183440: Efficacy Of Antenatal Maternal Supplementation With GOS/Inulin Prebiotics On Atopic Dermatitis Prevalence In High-Risk One-Year-Old Children |
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| Recruiting | N/A | 376 | Europe | PREBIOTICS, PLACEBO | Nantes University Hospital | Dermatitis, Atopic | 08/23 | 08/23 | | |
FETH, NCT03648645: Hypertensive Pregnant Women Monitored by Teletransmitted Self-measurements of Blood Pressure |
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| Active, not recruiting | N/A | 50 | Europe | Self measurement of blood pressure | Rennes University Hospital | Hypertension in Pregnancy | 11/23 | 11/23 | | |
Antenatal, NCT03116217: Validation of a Fetal Urine Peptidome-based Classifier to Predict Post-natal Renal Function in Posterior Urethral Valves |
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| Recruiting | N/A | 400 | Europe | | University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France | Posterior Urethral Valves | 12/23 | 12/23 | | |
| Recruiting | N/A | 322 | Europe | | University Hospital, Brest | Cholestasis of Pregnancy | 06/25 | 06/25 | | |
RANSPRE, NCT05521776: Impact of First-trimester Preeclampsia Screening on Perinatal and Maternal Morbidity |
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| Recruiting | N/A | 14500 | Europe | First-trimester preeclampsia screening (FMF triple test) | Assistance Publique - Hôpitaux de Paris, URC-CIC Paris Descartes Necker Cochin, INSERM, Epopé team | Preeclampsia (PE) | 10/25 | 10/25 | | |
| DESTRIEUX, Christophe |
| Recruiting | 3 | 486 | Europe | Intensified protocol, Stupp protocol | Centre Oscar Lambret, Association de Neuro-Oncologues d'Expression Francaise, Erasme University Hospital | Glioblastoma | 05/25 | 11/27 | | |
| BONNET-BRILHAULT, Frédérique |
NCT02878499: Do Sleep and Circadian Rhythm Disturbances Impact the Cognitive and Behavioural Development of Children With Autism? |
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| Recruiting | N/A | 105 | Europe | polysomnography | University Hospital, Strasbourg, France | Autism Spectrum Disorder | 12/22 | 02/23 | | |
| Garot, Denis |
| Recruiting | 3 | 270 | Europe | Placebos, Dobutamine | University Hospital, Limoges, Centre d'Investigation Clinique 1415 | Sepsis, Cardiomyopathies, Hypoperfusion, Left Ventricular Systolic Dysfunction | 12/25 | 12/25 | | |
NCT04612413: A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients |
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| Active, not recruiting | 2 | 160 | Europe, RoW | Allocetra-OTS, Placebo | Enlivex Therapeutics Ltd., Cato Research, Accelsiors CRO & Consultancy Services | Sepsis, Community-acquired Pneumonia, Urinary Tract Infections, Cholecystitis, Acute, Cholangitis Acute, Intraabdominal Infections | 12/24 | 03/25 | | |
| Recruiting | N/A | 350 | Europe | Blood samples, Tracheal Aspirates, Surplus of Broncho-alveolar lavage fluid | University Hospital, Tours | Community-acquired Pneumonia, Acute Respiratory Distress Syndrome, Innate Immunity | 09/24 | 03/25 | | |
POSTPONE, NCT06743529: Immediate Versus Substantiated Antibiotic Therapy in Suspected Non-Severe Ventilator-Associated Pneumonia |
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| Not yet recruiting | N/A | 686 | Europe, RoW | control group, Conservative strategy | Nantes University Hospital | Ventilator-Associated Pneumonia (VAP) | 10/28 | 01/29 | | |
| Recruiting | N/A | 20000 | Europe, RoW | VAP | European Clinical Research Alliance for Infectious Diseases (ECRAID), Centre Hospitalier Universitaire Dupuytren de Limoges (CHUL), Université de Genève (UNIGE), University Medical Center Utrecht (UMCU) | Ventilator Associated Pneumonia | 12/25 | 03/26 | | |
PROBIty, NCT05686577: How to Reduce Unnecessary Blood Cultures: Construction and Validation of a Predictive Score for Blood Culture Positivity in Intensive Care |
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| Completed | N/A | 2411 | Europe | no intervention | University Hospital, Tours | Infection, Bacterial, Infection, Fungal, Bacteremia | 09/23 | 10/23 | | |
| Corcia, Philippe |
| Terminated | 3 | 489 | Europe, Canada, US, RoW | Reldesemtiv, Placebo | Cytokinetics | Amyotrophic Lateral Sclerosis | 07/23 | 07/23 | | |
| Recruiting | 3 | 184 | Europe | Tauroursodeoxycholic Acid, TUDCA,Tudcabil, Taurolite | Humanitas Mirasole SpA, University of Ulm, University of Sheffield, University Hospital, Tours, KU Leuven, UMC Utrecht, University of Dublin, Trinity College, Bruschettini S.r.l., Istituto Superiore di Sanità, Motor Neurone Disease Association | Amyotrophic Lateral Sclerosis | 03/25 | 03/25 | | |
THERAMAG, NCT05136976: Rituximab Therapy in Anti-Myelin Associated Glycoprotein Patients With Characteristics of Good Responders |
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| Recruiting | 3 | 90 | Europe | Rituximab infusion, Mabthera, Placebo infusion, Sodium chloride (NaCl), Premedications | Centre Hospitalier Universitaire de Saint Etienne, Ministry of Health, France | Anti-MAG Neuropathy | 12/25 | 12/25 | | |
| Recruiting | 2 | 80 | Europe | NX210c, Placebo | Axoltis Pharma, ACT4ALS network | Amyotrophic Lateral Sclerosis | 02/26 | 02/26 | | |
| Active, not recruiting | 2 | 51 | Europe | IFB-088 50mg/day, IFB-088, Icerguastat, Placebo, Riluzole 100mg/day, Riluzole | InFlectis BioScience, InFlectis BioScience, | Amyotrophic Lateral Sclerosis, ALS | 01/25 | 01/25 | | |
| Completed | N/A | 1000 | Europe | Blood | University Hospital, Tours, Biogen | Amyotrophic Lateral Sclerosis | 03/22 | 05/23 | | |
| Active, not recruiting | N/A | 9 | Europe | Samples, Indirect calorimetry, Electrical bioimpedance | University Hospital, Tours | Amyotrophic Lateral Sclerosis | 01/23 | 01/24 | | |
| Completed | N/A | 55 | Europe | Measure of visual acuity, Interferometry, Samples of basal tears, Central corneal sensitivity, Slit lamp examination and undilated fundus, Conjunctival impression, Evaluation of the corneal innervation | University Hospital, Tours | Amyotrophic Lateral Sclerosis | 09/23 | 09/23 | | |
FG-CoALS, NCT06147843: French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis |
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| Recruiting | N/A | 1000 | Europe | Blood sample | University Hospital, Limoges, National Research Agency, France, Centre de Recherche en biomédecine de Strasbourg INSERM UMR-S1118, Institut du Cerveau et de la Moelle épinière, Institut National de la Santé et de la Recherche Médical - délégation Grand Ouest INSERM U1253, Klinik für Neurologie, Universitäts- und Rehabilitationskliniken Ulm (RKU), Centre de Données Cliniques et de Recherche CDCR, UMR Inserm U1253-IBRain-Neurogénétique et Physiopathologie Neuronale, France Cohorte | Amyotrophic Lateral Sclerosis | 09/27 | 09/29 | | |
| Recruiting | N/A | 50 | Europe | | University Hospital, Limoges | Amyotrophic Lateral Sclerosis | 12/24 | 12/24 | | |
| Recruiting | N/A | 600 | Europe | Saliva sample | ZIWIG, Monitoring Force Group | Amyotrophic Lateral Sclerosis, Sporadic, Amyotrophic Lateral Sclerosis | 07/25 | 07/25 | | |
| Recruiting | N/A | 1000 | Europe | biomarkers (composite analysis) | University Hospital, Lille | Amyotrophic Lateral Sclerosis, Motor Neuron Disease | 01/26 | 01/26 | | |
| GISSOT, Valérie |
REMBAU, NCT02423499: Features Emotional Responses in Adults With Autism: Comparison With Bipolar Disorder |
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| Recruiting | N/A | 90 | Europe | | University Hospital, Tours | Autism Spectrum Disorder, Bipolar Disorder | 05/21 | 05/21 | | |
| Recruiting | N/A | 30 | Europe | | University Hospital, Tours, Kahler Communication France | Communication, Personality | 09/21 | 12/21 | | |
| Completed | N/A | 815 | Europe, US, RoW | | BioMérieux, Vanderbilt University Medical Center, Centre d'Investigation Clinique - Limoges | Infection, Sepsis | 05/22 | 05/22 | | |
| Completed | N/A | 19 | Europe | 24h urine, urine sample | University Hospital, Tours | Lymphangioleiomyomatosis, Tuberous Sclerosis Complex | 10/22 | 10/22 | | |
| Recruiting | N/A | 60 | Europe | Cerebral neuroinflammation evaluation | University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France | Depressive Disorder | 01/24 | 01/24 | | |
| Completed | N/A | 55 | Europe | Measure of visual acuity, Interferometry, Samples of basal tears, Central corneal sensitivity, Slit lamp examination and undilated fundus, Conjunctival impression, Evaluation of the corneal innervation | University Hospital, Tours | Amyotrophic Lateral Sclerosis | 09/23 | 09/23 | | |
COVIFERON, NCT06762002: Impaired Type I IFN Immunity Due to Autoantibodies or a Genetic Defect: a Prospective National Cohort |
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| Not yet recruiting | N/A | 500 | Europe | blood sample | Institut National de la Santé Et de la Recherche Médicale, France | Immunology, Allergy, Genetic Diseases, Infectious Diseases | 01/29 | 01/29 | | |
BARRIG, NCT06670937: Role of BARriers in IgG-Pathogen Interactions At the Mucosal Surface in Human Airways |
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| Not yet recruiting | N/A | 30 | Europe | Induced sputum, Blood sample | University Hospital, Tours | Bronchiectasis Adult | 01/26 | 01/26 | | |
| Machet, Laurent |
RITUX-MMP, NCT03295383: Randomized Clinical Trial Comparing the Safety and Efficacy of Rituximab Versus Oral Cyclophosphamide in Severe Forms of Mucous Membrane Pemphigoid |
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| Recruiting | 3 | 130 | Europe | Rituximab 1g IV, Cyclophosphamide 50Mg Oral Tablet, Placebo of Rituximab, Placebo Oral Tablet | University Hospital, Rouen | Severe Forms of Mucous Membrane Pemphigoid | 11/22 | 11/23 | | |
CANNABITCH, NCT06435299: Efficacy and Tolerance of Cannabidiol in Patients with Severe Pruritus: a Multicenter, Double-blind, Randomized, Placebo-controlled Study |
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| Not yet recruiting | 3 | 218 | Europe | Cannabis oil, Placebo | University Hospital, Brest | Pruritus | 07/27 | 07/27 | | |
| Active, not recruiting | 2 | 170 | Europe, US | IPH4102, lacutamab | Innate Pharma | Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides/Sezary Syndrome | 10/23 | 01/26 | | |
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| Active, not recruiting | 2 | 271 | Europe | Nivolumab + Ipilimumab, Encorafenib + Binimetinib | European Organisation for Research and Treatment of Cancer - EORTC | Unresectable Stage III Melanoma, Stage IV Melanoma | 10/23 | 01/27 | | |
| Recruiting | N/A | 225 | Europe | Sampling | University Hospital, Tours | Vasculitis | 12/37 | 12/37 | | |
| Recruiting | N/A | 9000 | Europe | | University Hospital, Lille | Adnexal Tumor of Skin, Merkel Cell Carcinoma, Advanced Basal Cell Carcinoma Requiring Systemic Treatment | 12/25 | 12/25 | | |
| SALIBA, Elie |
EPIREMED, NCT02757794: Long-term Effects of Visual Spatial Working Memory Training Program Performed at Preschool Age in Very Preterm Infants With Visual Spatial Working Memory Deficit. A Randomized Controlled Trial |
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| Completed | N/A | 166 | Europe | computerized cognitive remediation program, standard remediation | Assistance Publique Hopitaux De Marseille | Children Born Extremely Premature, Disturbance of Visuo-spatial Working Memory | 08/19 | 08/19 | | |
| MAILLOT, François |
| Recruiting | N/A | 225 | Europe | Sampling | University Hospital, Tours | Vasculitis | 12/37 | 12/37 | | |
MATAC, NCT06444477: Molecular Analysis of Thrombocytopenia and Cancer (): Investigating Antigenic Mimicry Between Platelets and Tumor Cells in Patients With Immune Thrombocytopenia (ITP) Associated With Cancer |
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| Not yet recruiting | N/A | 70 | Europe | ITP and cancer | University Hospital, Bordeaux | Immune Thrombocytopenia, Immune Thrombocytopenic Purpura, Neoplasms, Cancer | 12/24 | 12/24 | | |
| Recruiting | N/A | 350 | Europe | Blood samples, Tracheal Aspirates, Surplus of Broncho-alveolar lavage fluid | University Hospital, Tours | Community-acquired Pneumonia, Acute Respiratory Distress Syndrome, Innate Immunity | 09/24 | 03/25 | | |
| Mercier, Emmanuelle |
| Recruiting | 3 | 270 | Europe | Placebos, Dobutamine | University Hospital, Limoges, Centre d'Investigation Clinique 1415 | Sepsis, Cardiomyopathies, Hypoperfusion, Left Ventricular Systolic Dysfunction | 12/25 | 12/25 | | |
| Recruiting | 3 | 20000 | Europe, Canada, Japan, US, RoW | Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, IFN-β1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, acetylsalicylic acid, P2Y12 inhibitor, Clopidogrel, Prasugrel, Ticagrelor, No simvastatin, Simvastatin, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Ramipril, Lisinopril, Perindopril, Enalapril, Trandolapril, Captopril, Angiotensin Receptor Blockers, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Paxlovid, Remdesivir, Nirmatrelvir/ritonavir + remdesivir | UMC Utrecht, Australian and New Zealand Intensive Care Research Centre, Medical Research Institute of New Zealand, Unity Health, Berry Consultants, Global Coalition for Adaptive Research, University of Pittsburgh Medical Center, Intensive Care National Audit & Research Centre, St. Marianna University School of Medicine, Nat Intensive Care Surveillance - MORU, National University Hospital, Singapore | Community-acquired Pneumonia, Influenza, COVID-19 | 02/26 | 02/28 | | |
NCT05962606: Safety and Efficacy of AON-D21 in Severe Community-Acquired Pneumonia. |
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| Recruiting | 2 | 150 | Europe | AON-D21, Placebo | Aptarion Biotech AG | Community-acquired Pneumonia | 05/26 | 06/26 | | |
NESOI-2, NCT05867875: Non-invasive Early Oxygen- Reserve-index (ORI) Determination to Prevent Hypoxaemia During Endotracheal Intubation |
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| Recruiting | N/A | 950 | Europe | Unblinded ORI values, Blinded ORI values | Nantes University Hospital | Intensive Care Unit | 08/25 | 09/25 | | |
| Recruiting | N/A | 350 | Europe | Blood samples, Tracheal Aspirates, Surplus of Broncho-alveolar lavage fluid | University Hospital, Tours | Community-acquired Pneumonia, Acute Respiratory Distress Syndrome, Innate Immunity | 09/24 | 03/25 | | |
NUTRIREA-4, NCT06581939: Impact of an Early and Extended Rehabilitation Program Combining Individually Tailored Nutrition and Physical Activities on Patient Outcomes After Invasive Mechanical Ventilation and Vasopressor Therapy in the ICU |
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| Recruiting | N/A | 830 | Europe | Rehabilitation group, Control group | Nantes University Hospital | Mechanical Ventilation | 06/27 | 12/27 | | |
| Active, not recruiting | N/A | 17 | Europe | ECCO2R | Assistance Publique - Hôpitaux de Paris, Ministry of Health, France, Xenios AG | COPD Acute Exacerbation | 05/24 | 03/25 | | |
| EHRMANN, Stephan |
INASED, NCT04341350: Comparison of an Inhaled Sedation Strategy to an Intravenous Sedation Strategy in Intensive Care Unit Patients Treated with Invasive Mechanical Ventilation |
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| Recruiting | 3 | 250 | Europe | Propofol + analgesic drug, Isoflurane + analgesic drug | University Hospital, Brest | Prevention of Delirium | 08/25 | 08/26 | | |
| Not yet recruiting | N/A | 754 | Europe | Strategy for continuing oral intake, Fasting strategy | University Hospital, Tours | Patient in Acute Respiratory Failure, Continuation of Oral Intake | 09/27 | 10/27 | | |
| Recruiting | N/A | 350 | Europe | Blood samples, Tracheal Aspirates, Surplus of Broncho-alveolar lavage fluid | University Hospital, Tours | Community-acquired Pneumonia, Acute Respiratory Distress Syndrome, Innate Immunity | 09/24 | 03/25 | | |
DC-SCENIC, NCT05627167: Daytime Cyclic Enteral Nutrition Versus Standard Continuous Enteral Nutrition in the Intensive Care Unit: a Pilot Randomized Controlled Trial |
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| Recruiting | N/A | 318 | Europe | day time cyclic nutrition, continuous nutrition | Centre Hospitalier le Mans | Enteral Nutrition | 02/25 | 02/26 | | |
IMPROVE, NCT04148443: Impact of Preoxygenation Time on End-tidal Oxygen Concentration and on Hypoxic Events Occurring After Intubation in the Intensive Care Unit. |
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| Withdrawn | N/A | 110 | Europe | Preoxygenation, Preoxygenation (longer) | Centre Hospitalier Régional d'Orléans | Preoxygenation, Intubation, Intensive Care Unit | 12/24 | 12/24 | | |
| Recruiting | N/A | 300 | Europe | quality of life questionnaire | University Hospital, Tours | SARS-CoV 2 Pneumonia | 05/25 | 05/25 | | |
| LINASSIER, Claude |
SPICI, NCT05219318: Treatment Pause Versus Treatment Continuation in IMDC Good or Intermediate Risk With Only One Adverse Prognostic Factor in mRCC Patients With an Objective Response at 12 Months of Treatment With PD1/ PDL1 ICIs + VEGFR-Tyrosine Kinase Inhibitors |
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| Recruiting | 3 | 372 | Europe | Combination PD-1/PD-L1 ICI + VEGFR-TKI, Treatment pause | University Hospital, Bordeaux | Metastatic Renal Cell Carcinoma, Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC Score | 01/25 | 01/25 | | |
| Recruiting | 3 | 300 | Europe | Darolutamide 300 mg, Nubeqa®, Placebo, Androgen deprivation therapy, ADT | UNICANCER, Bayer | Prostate Cancer Metastatic | 03/28 | 09/37 | | |
CINECI, NCT04487457: Prospective Study to Evaluate the Blood Kinetics of Immune Cells and Immunosuppressive Cytokines After Exposure to an Immunity Checkpoint Inhibitor (ICI): Study of the Impact of Chemotherapy |
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| Completed | N/A | 31 | Europe | Blood samples | University Hospital, Tours | Non Small Cell Lung Cancer, Bladder Cancer, ENT Cancer | 09/22 | 09/22 | | |
PRISM care, NCT02849535: Impact of the PRISM-care Multidisciplinary Oncology Program on Secured Drug Intake of Patients With Kidney Cancer |
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| Recruiting | N/A | 190 | Europe | PRISM care program | Hospices Civils de Lyon | Metastatic Renal Cell Carcinoma | 04/23 | 04/23 | | |
PROMECI, NCT05415787: Evaluation of the Technical Feasibility of Testing ct DNA for Homologous Recombination Gene Variants in Metastatic Prostate Cancer. |
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| Completed | N/A | 40 | Europe | Blood sample, Urine sample | University Hospital, Tours | Circulating Tumor DNA, Metastatic Prostate Cancer | 01/24 | 01/24 | | |
| ZEMMOURA, Ilyess |
| Recruiting | 3 | 486 | Europe | Intensified protocol, Stupp protocol | Centre Oscar Lambret, Association de Neuro-Oncologues d'Expression Francaise, Erasme University Hospital | Glioblastoma | 05/25 | 11/27 | | |
POLO, NCT04702581: A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than Surgery |
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| Recruiting | 3 | 280 | Europe | PCV chemotherapy, Radiotherapy and PCV chemotherapy | Hospices Civils de Lyon | Oligodendroglioma, Low-grade Oligodendroglioma, 1p19q Codeletion | 12/30 | 12/30 | | |
| BRUYERE, Franck |
SUGAR, NCT05826509: SUrGery with or Without DARolutamide in High-risk And/or Locally Advanced Prostate Cancer |
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| Recruiting | 2 | 240 | Europe | Surgery alone, Peri-operative darolutamide + surgery. | Institut Claudius Regaud, Bayer | Prostate Cancer | 05/30 | 05/30 | | |
| Completed | N/A | 296 | Europe | prostate biopsy, Urinary sampling, Rectal swabbing before biopsies are performed | Centre Hospitalier Universitaire de Nice | Prostatic Neoplasm | 10/22 | 06/23 | | |
PROMECI, NCT05415787: Evaluation of the Technical Feasibility of Testing ct DNA for Homologous Recombination Gene Variants in Metastatic Prostate Cancer. |
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| Completed | N/A | 40 | Europe | Blood sample, Urine sample | University Hospital, Tours | Circulating Tumor DNA, Metastatic Prostate Cancer | 01/24 | 01/24 | | |
| Recruiting | N/A | 50 | Europe | urethral bladder resection | University Hospital, Tours | Elastographic Measurement, Intravesical Pressure Measurement | 02/25 | 02/25 | | |
| Active, not recruiting | N/A | 280 | Europe | Low insufflation pressure (7mm Hg) for Robotic Assisted Partial Nephrectomy, Standard insufflation pressure (12mm Hg) for Robotic Assisted Partial Nephrectomy | University Hospital, Bordeaux | Kidney Tumors Treated With Minimally Invasive Surgery | 04/24 | 05/24 | | |
AblaJ, NCT04913753: Relevance of the Urine Bacterial Culture Performed Before Double J Ablation for Post-operative Urinary Tract Infection Prevention |
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| Recruiting | N/A | 2200 | Europe | CBEU, No CBEU | University Hospital, Tours | Urinary Infection | 09/24 | 10/24 | | |
| Recruiting | N/A | 30000 | Europe, RoW | Radical nephrectomy versus partial nephrectomy (according surgeon judgement) | University Hospital, Bordeaux | Kidney Cancer | 12/40 | 12/40 | | |
| Active, not recruiting | N/A | 1360 | Europe | Comparisons between the Prostatic urethral lift (PUL) and the TURP/Laser cohorts, Comparison between the Prostatic urethral lift (PUL) and the SNDS cohorts | University Hospital, Bordeaux, Bordeaux PharmacoEpi | Benign Prostatic Hyperplasia | 12/24 | 06/26 | | |
| Recruiting | N/A | 500 | Europe | | Centre Hospitalier Universitaire, Amiens | Bladder Cancer, Cystoscopy, Artificial Intelligence | 05/27 | 05/29 | | |
| Legras, Annick |
| Recruiting | 3 | 270 | Europe | Placebos, Dobutamine | University Hospital, Limoges, Centre d'Investigation Clinique 1415 | Sepsis, Cardiomyopathies, Hypoperfusion, Left Ventricular Systolic Dysfunction | 12/25 | 12/25 | | |
REAVD3D, NCT04222764: Evaluation of the Right Ventricular Systolic Function Using Real-time Three-dimensional Echocardiography in Intensive Care Unit Patients |
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| Completed | N/A | 341 | Europe | Real-time three-dimensional echocardiography | University Hospital, Limoges | Ventricular Dysfunction, Right, Lung Diseases, Intensive Care Units | 09/23 | 09/23 | | |
| Recruiting | N/A | 350 | Europe | Blood samples, Tracheal Aspirates, Surplus of Broncho-alveolar lavage fluid | University Hospital, Tours | Community-acquired Pneumonia, Acute Respiratory Distress Syndrome, Innate Immunity | 09/24 | 03/25 | | |
| Desmidt, Thomas |
NCT03454646: Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL) |
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| Not yet recruiting | 4 | 1205 | Europe | cholinesterase inhibitors (CI) (donepezil, galantamine or rivastigmine) | University Hospital, Bordeaux | Alzheimer Disease, Cholinesterase Inhibitors | 04/27 | 09/27 | | |
| Recruiting | 3 | 1500 | Europe, RoW | Donanemab, (LY3002813), Placebo | Eli Lilly and Company | Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders | 04/27 | 04/27 | | |
| Recruiting | N/A | 60 | Europe | EMONO, Medical Air | University Hospital, Tours | Late-Life Depression, Resistant Depression, Treatment | 12/24 | 12/24 | | |
| Recruiting | N/A | 60 | Europe | Cerebral neuroinflammation evaluation | University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France | Depressive Disorder | 01/24 | 01/24 | | |
| Recruiting | N/A | 300 | Europe | Ultrasound examination | University Hospital, Tours | Neurocognitive Disorders | 03/26 | 03/31 | | |
| Laffon, Marc |
| Recruiting | 3 | 360 | Europe | Milrinone 1 Mg/mL Solution for Injection, Corotrope, Saline solution for injection, Sodium Chloride 0.9% | University Hospital, Angers | Vasospasm | 08/23 | 02/24 | | |
| Not yet recruiting | N/A | 5000 | Europe | questionnaire filling | Centre Hospitalier Universitaire de NÄ«mes | Critical Illness, Covid19, Stress Disorders, Post-Traumatic | 09/22 | 09/22 | | |
ACUCESAR, NCT06119971: Effect of Acupressure on the "Yin-Tang" and "Shen-Men" Points on Pre and Postoperative Anxiety in Elective Caesarean Section: a Prospective, Single-blind, Randomised, Controlled Trial |
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| Completed | N/A | 44 | Europe | ACUPRESSURE | University Hospital, Tours | Cesarean Section, Pregnancy, Preoperative Anxiety | 03/23 | 03/23 | | |
OSPAIL, NCT05562141: Oxidative Stress in the Patient With Peroperative Analgesia by Intravenous Lidocaine |
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| Completed | N/A | 20 | Europe | Blood sample | University Hospital, Tours | Oxidative Stress, Analgesia | 07/23 | 07/23 | | |
| Adam, Sylvain Marchand |
| Active, not recruiting | 3 | 597 | Europe, RoW | Placebo, Inhaled Treprostinil, Tyvaso, Treprostinil Ultrasonic Nebulizer | United Therapeutics | Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease | 07/25 | 07/25 | | |
EXAFIP2, NCT05674994: Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis |
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| Recruiting | 3 | 110 | Europe | Methylprednisone/Prednisone, Placebo | Fondation Hôpital Saint-Joseph | Acute Exacerbation of Idiopathic Pulmonary Fibrosis | 10/25 | 12/26 | | |
NCT05032066: A Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic Pulmonary Fibrosis |
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| Terminated | 2 | 153 | Europe, Canada, Japan, US, RoW | HZN-825, Placebo | Amgen | Idiopathic Pulmonary Fibrosis | 07/24 | 01/25 | | |
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AKAPI, NCT06585020: Amikacin Liposome Inhalation Suspension for Treatment of Mycobacterium Xenopi Pulmonary Infection |
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| Not yet recruiting | 2 | 190 | Europe | Arikayce, standard treatment | Centre Hospitalier Universitaire, Amiens, University Hospital, Angers, Hospital Avicenne, University Hospital, Bordeaux, University Hospital, Brest, CH Compiègne, Créteil Hospital, Centre Hospitalier Universitaire Dijon, University Hospital, Grenoble, Centre Hospitalier le Mans, Hôpital de la Croix-Rousse, APHM - Nord, Hôpital Saint Joseph, CH Mulhouse, CH Orléans, Tenon Hospital, Paris, Hôpital Necker-Enfants Malades, CH PERPIGNAN, Poitiers University Hospital, CH Pontoise, CHU de Reims, Rennes University Hospital, CHU de Rouen - Accueil, Central Hospital Saint Quentin, IHU Strasbourg, University Hospital, Tours, CH Abbeville, CH Cannes | Mycobacterium; Xenopi, Lung Diseases | 08/26 | 08/27 | | |
| Completed | N/A | 19 | Europe | 24h urine, urine sample | University Hospital, Tours | Lymphangioleiomyomatosis, Tuberous Sclerosis Complex | 10/22 | 10/22 | | |
| BAKHOS, DAVID |
| Recruiting | N/A | 102 | Europe | ECochG monitored CI surgery incl. corrective action guide, Routine CI surgery without ECochG monitoring | Advanced Bionics AG | Hearing Loss, Sensorineural, Severe-to-profound Hearing Loss | 06/26 | 06/26 | | |
| Recruiting | N/A | 150 | Europe | Wicking, No wicking | University Hospital, Tours | Post-Op Complication, Otologic Disease | 05/25 | 05/26 | | |
PULSE, NCT06013215: Electrical Impulse Parameters and Neuronal Population in the Cochlear Implanted Patient- |
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| Not yet recruiting | N/A | 15 | NA | Cochlear implant (Oticon) stimulation parameter optimization | University Hospital, Tours | Sensorineural Hearing Loss | 11/25 | 11/25 | | |
ROBIICCA, NCT05696171: Clinical Evaluation of Robot-assisted Cochlear Implant Insertion in Adults Using RobOtol® Compared to Manual Insertion |
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| Recruiting | N/A | 550 | Europe | Cochlear implant manual insertion, Cochlear implant robotized insertion | Nantes University Hospital | Profound Bilateral Hearing Loss | 05/26 | 05/26 | | |
| MARCHAND-ADAM, Sylvain |
| Recruiting | 4 | 378 | Europe | pirfenidone and nintedanib, pirfenidone or nintedanib | Hospices Civils de Lyon, Ministry of Health | Progressive Idiopathic Pulmonary Fibrosis | 01/26 | 01/26 | | |
| Terminated | 3 | 372 | Europe, US, RoW | Pamrevlumab, FG-3019, Placebo | FibroGen | Idiopathic Pulmonary Fibrosis | 09/23 | 09/23 | | |
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| Completed | 3 | 397 | Europe, Canada, Japan, US, RoW | GSK3511294, Depemokimab, Placebo | GlaxoSmithKline, Iqvia Pty Ltd | Asthma | 04/24 | 04/24 | | |
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| Active, not recruiting | 3 | 1667 | Europe, Canada, Japan, US, RoW | GSK3511294 (Depemokimab), Mepolizumab, Benralizumab, Placebo, Standard of care (SoC), Pre-filled Syringes (PFS) | GlaxoSmithKline, Iqvia Pty Ltd | Asthma | 10/25 | 10/25 | | |
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EvER-ILD2, NCT05596786: Evaluation of Efficacy and Safety of Rituximab in Patients With Progressive Interstitial Lung Disease (ILD) With Inflammatory Component: a Multicentre Double-blind Placebo-controlled Randomized Trial |
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| Recruiting | 3 | 126 | Europe | Rituximab, Placebo | University Hospital, Tours | Lung Diseases | 07/26 | 07/26 | | |
