University Hospital of TOURS
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 93 Trials 
129 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Perrotin, Franck
BIGW, NCT03435458: Balloon to Induce Labor in Generous Women.

Terminated
3
429
Europe, RoW
Balloon catheter + oral misoprostol, Oral misoprostol alone
University Hospital, Toulouse
Maternal Obesity
02/23
02/23
APPART, NCT05625724: Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology

Recruiting
3
1164
Europe
Aspirin, Placebo
University Hospital, Toulouse
ART, Pre-Eclampsia
05/25
05/26
PREGRALL, NCT03183440: Efficacy Of Antenatal Maternal Supplementation With GOS/Inulin Prebiotics On Atopic Dermatitis Prevalence In High-Risk One-Year-Old Children

Recruiting
N/A
376
Europe
PREBIOTICS, PLACEBO
Nantes University Hospital
Dermatitis, Atopic
08/23
08/23
FETH, NCT03648645: Hypertensive Pregnant Women Monitored by Teletransmitted Self-measurements of Blood Pressure

Active, not recruiting
N/A
50
Europe
Self measurement of blood pressure
Rennes University Hospital
Hypertension in Pregnancy
11/23
11/23
Antenatal, NCT03116217: Validation of a Fetal Urine Peptidome-based Classifier to Predict Post-natal Renal Function in Posterior Urethral Valves

Recruiting
N/A
400
Europe
University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France
Posterior Urethral Valves
12/23
12/23
INTREPIDE, NCT05197387: Association of Intrahepatic Cholestasis of Pregnancy and Chronic Placental Inflammation

Recruiting
N/A
322
Europe
University Hospital, Brest
Cholestasis of Pregnancy
06/25
06/25
RANSPRE, NCT05521776: Impact of First-trimester Preeclampsia Screening on Perinatal and Maternal Morbidity

Recruiting
N/A
14500
Europe
First-trimester preeclampsia screening (FMF triple test)
Assistance Publique - Hôpitaux de Paris, URC-CIC Paris Descartes Necker Cochin, INSERM, Epopé team
Preeclampsia (PE)
10/25
10/25
DESTRIEUX, Christophe
StrateGlio, NCT03663725 / 2018-000410-38: Treatment Intensification With Temozolomide in Adults With a Glioblastoma

Recruiting
3
486
Europe
Intensified protocol, Stupp protocol
Centre Oscar Lambret, Association de Neuro-Oncologues d'Expression Francaise, Erasme University Hospital
Glioblastoma
05/25
11/27
LABBE, Catherine
NCT05714891: Neoadjuvant Platform Trial in Non-Small Cell Lung Cancer

Active, not recruiting
2
4
Canada
JDQ443
Canadian Cancer Trials Group, Novartis
NSCLC
08/26
03/28
RIVAL, Gilles
BPCO, NCT05577767: Does Longitudinal Nursing Follow-up Improve Smoking Cessation in Patients Referred for COPD Screening

Recruiting
N/A
233
Europe
Centre Hospitalier de Valence
COPD, Nurse's Role
09/25
09/26
HAGE, Wissam EL
DISCO, NCT03758105: Transcranial Direct Current Stimulation (tDCS) Cost-utility-analysis in Medical Care on Depressive Episode With One Drug Therapy Failure.

Active, not recruiting
N/A
214
Europe
tDCS associated with usual care, Usual care
Nantes University Hospital
Depression
11/23
11/23
DEPREDICT, NCT03690856: Clinical and Neurobiological Profile Predictive of Pejorative Outcome of Depression

Recruiting
N/A
150
Europe
inflammatory, neuropsychological and neuroimaging assessment
Rennes University Hospital
Depression
01/24
01/24
MINDDE, NCT05654948: Characterisation of Fundamental Decision Making in People Suffering From a Characterised Depressive Episode

Completed
N/A
80
Europe
computerised cognitive performance test : MindPulse, MindPulse
University Hospital, Tours
Depressive Episode
04/24
04/24
MULLEMAN, Denis
SEQUENS-RA, NCT05428488: Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis

Recruiting
3
220
Europe, RoW
Abatacept (W12-W48), TNF Inhibitor (W12-W48), TNF Inhibitor (W0-W12)
University Hospital, Montpellier
Rheumatoid Arthritis
11/24
11/25
CRI-RA, NCT04870203: Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis

Recruiting
3
178
Europe, RoW
baricitinib treatment, adalimumab, Placebo
University Hospital, Bordeaux, Eli Lilly and Company, Biogen, Ministry for Health and Solidarity, France
Rheumatoid Arthritis
12/25
12/25
RESPOND-IL17, NCT05812157: Optimizing Anti-IL17 Antibody Therapy by Associating Fiber Supplementation to Correct Treatment-aggravated Gut Dysbiosis in Axial Spondyloarthritis -

Recruiting
N/A
36
Europe
Daily dietary supplementation with Fibruline, Anti-IL-17 therapy
Centre Hospitalier Universitaire de Nīmes
Axial Spondyloarthritis
12/26
12/26
CAMUS, Vincent
ECHELON-3, NCT04404283 / 2020-002686-33: Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

Hourglass Jan 2023 - Dec 2023 : From:ECHELON-3 trial in combination with brentuximab vedotin and rituximab for r/r DLBCL
Active, not recruiting
3
240
Europe, Canada, US, RoW
Brentuximab vedotin, Rituximab, Lenalidomide, Placebo
Seagen Inc.
Diffuse Large B-cell Lymphoma
05/25
04/27
NCT03870776: RESIST : Administration of MAP4343 in Antidepressant Non-Responders Patients Experiencing a Major Depressive Episode

Active, not recruiting
2
110
Europe
MAP4343, Placebo
Mapreg, Eurofins Optimed
Depression
12/24
03/25
SGN35-032, NCT04569032 / 2020-002336-74: A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Active, not recruiting
2
82
Europe, US, RoW
brentuximab vedotin, ADCETRIS, cyclophosphamide, doxorubicin, prednisone
Seagen Inc.
Peripheral T-cell Lymphoma
05/24
12/25
PAMAL, NCT03946332: Physical Activity for Myeloma Autograft Longitudinal Study

Recruiting
N/A
100
Europe
Physical exercises, Optional physical exercises
Centre Hospitalier Universitaire, Amiens, University Hospital, Rouen, University Hospital, Caen
Physical Activity, Multiple Myeloma, Quality of Life
05/23
12/23
InflaDep, NCT03314155: Cerebral Neuroinflammation During Major Depressive Episode

Recruiting
N/A
60
Europe
Cerebral neuroinflammation evaluation
University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France
Depressive Disorder
01/24
01/24
CELERITY, NCT06744075: Study of the Clearance of Minimal Residual Disease Measured At the End of First-line Treatment in Patients with Lymphoma

Not yet recruiting
N/A
108
Europe
Blood assessment
Centre Henri Becquerel
B-cell Lymphoma, Hodgkin Lymphoma
12/25
12/27
PEPAMARKER, NCT05384392: Biomarkers Predictive of Thymic Evolution and Therapeutic Response at 2 Years in Patients With a First Psychotic Episode

Not yet recruiting
N/A
217
Europe
Recorded interview, Clinical scales, Blood sample, MRI scans of the brain
University Hospital, Brest
First-episode Psychosis
01/26
01/28
RT-CAR, NCT05675982: Real-Time Monitoring of Circulating Tumor DNA and Study of Prognostic Factors in Patients Treated With CAR-T Cells

Not yet recruiting
N/A
40
Europe
CAR-T cells monitoring
Centre Henri Becquerel
Diffuse Large B Cell Lymphoma
01/25
01/26
RESILIENCE, NCT05223413: REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs

Recruiting
N/A
608
Europe
RIPC, Simulated RIPC (Sham)
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, European Commission
Anthracycline-induced Cardiac Toxicity, Lymphoma
08/25
05/26
PTCL-SEQ, NCT06089941: Circulating Tumor DNA Sequencing in Patients With Peripheral T-cell Lymphomas

Not yet recruiting
N/A
45
Europe
circulating tumoral DNA detection
Centre Henri Becquerel
Peripheral T Cell Lymphoma
11/25
11/26
CAMIL, NCT04824950: Circulating Tumor DNA in Primary Mediastinal Large B-cell Lymphoma (PMBL)

Recruiting
N/A
87
Europe
Circulating tumor DNA monitoring
Centre Henri Becquerel
Primary Mediastinal Large B-cell Lymphoma
03/28
03/28
TRANSCRIPT, NCT05444712: Transplantation After Complete Response In Patients With T-cell Lymphoma

Recruiting
N/A
204
Europe
Chemotherapy + follow up, Chemotherapy + ASCT + follow up
Hospices Civils de Lyon
Peripheral T Cell Lymphoma
04/28
04/28
GISSOT, Valérie
REMBAU, NCT02423499: Features Emotional Responses in Adults With Autism: Comparison With Bipolar Disorder

Recruiting
N/A
90
Europe
University Hospital, Tours
Autism Spectrum Disorder, Bipolar Disorder
05/21
05/21
COCACE, NCT04533126: Channels of Communication & Brain Functioning: Pilot fMRI Study

Recruiting
N/A
30
Europe
University Hospital, Tours, Kahler Communication France
Communication, Personality
09/21
12/21
SepSIGN, NCT04261621: Early Identification of SEPsis SIGNs in Emergency Department

Completed
N/A
815
Europe, US, RoW
BioMérieux, Vanderbilt University Medical Center, Centre d'Investigation Clinique - Limoges
Infection, Sepsis
05/22
05/22
LAM-CAK, NCT05323370: Lymphangioleiomyomatosis, a Study on Cathepsin K

Completed
N/A
19
Europe
24h urine, urine sample
University Hospital, Tours
Lymphangioleiomyomatosis, Tuberous Sclerosis Complex
10/22
10/22
InflaDep, NCT03314155: Cerebral Neuroinflammation During Major Depressive Episode

Recruiting
N/A
60
Europe
Cerebral neuroinflammation evaluation
University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France
Depressive Disorder
01/24
01/24
LARMOMIQUE, NCT04953286: Ocular Surface Metabolo-lipidomics in Lateral Amyotrophic Sclerosis

Completed
N/A
55
Europe
Measure of visual acuity, Interferometry, Samples of basal tears, Central corneal sensitivity, Slit lamp examination and undilated fundus, Conjunctival impression, Evaluation of the corneal innervation
University Hospital, Tours
Amyotrophic Lateral Sclerosis
09/23
09/23
COVIFERON, NCT06762002: Impaired Type I IFN Immunity Due to Autoantibodies or a Genetic Defect: a Prospective National Cohort

Not yet recruiting
N/A
500
Europe
blood sample
Institut National de la Santé Et de la Recherche Médicale, France
Immunology, Allergy, Genetic Diseases, Infectious Diseases
01/29
01/29
BARRIG, NCT06670937: Role of BARriers in IgG-Pathogen Interactions At the Mucosal Surface in Human Airways

Not yet recruiting
N/A
30
Europe
Induced sputum, Blood sample
University Hospital, Tours
Bronchiectasis Adult
01/26
01/26
COTTIER, Jean-Philippe
InflaDep, NCT03314155: Cerebral Neuroinflammation During Major Depressive Episode

Recruiting
N/A
60
Europe
Cerebral neuroinflammation evaluation
University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France
Depressive Disorder
01/24
01/24
CAMOMILLE, NCT04113395: Concordance and Accuracy of MRI in the Detection of Meningiomas: Optimizing Sequences With Low Doses of Gadolinium

Recruiting
N/A
500
Europe
sequences T1 FE, T1 TFE sequences
Fondation Ophtalmologique Adolphe de Rothschild
Meningioma
12/25
12/25
RESYSTAA, NCT05391113: REward SYSTem in Autism Spectrum Disorder and Addictive Disorder

Recruiting
N/A
78
Europe
MRI, Functionnal MRI, EEG, Electro Encephalography
University Hospital, Tours, INSERM UMR-1253, Tours, France
Autism Spectrum Disorder
07/26
01/27
RIBEIRO, Maria Joao SANTIAGO
KING, NCT05512403: Evaluation of Diagnostic Performances of 18F-FDOPA PET KInetics

Recruiting
3
88
Europe
PET/CT with 18F-DOPA
Central Hospital, Nancy, France
Glioma
12/25
10/26
VA-BAT, NCT05011383: High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

Recruiting
2
51
US
High dose testosterone, Bipolar androgen therapy
VA Office of Research and Development
Metastatic Prostate Cancer
08/26
08/27
PROGRESS10, NCT04650165: 10-year Progression of Diabetic Retinopathy: Identification of Signs and Surrogate Outcomes

Completed
N/A
119
Europe
Association for Innovation and Biomedical Research on Light and Image
Diabetic Retinopathy
03/24
03/24
NHLBI-MDS, NCT02775383: The National Myelodysplastic Syndromes (MDS) Study

Active, not recruiting
N/A
3500
US, RoW
Therapeutic
National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI)
Myelodysplastic Syndromes (MDS)
03/25
06/25
EYE-MARKER, NCT02500862: Characterization of Potential Biomarkers of Eye Disease and Vision

Active, not recruiting
N/A
100
Europe
Association for Innovation and Biomedical Research on Light and Image
Eye Disease
12/26
12/26
BLOUIN, Pascale
CAALL-F01, NCT02716233: A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents

Recruiting
3
1578
Europe
pegaspargase 1250 IU/m2 x 2, ONCASPAR 1250 IU/m2 x 2, pegaspargase 2500 IU/m2 x 1, ONCASPAR 2500 IU/m2 x 1
Assistance Publique - Hôpitaux de Paris, Shire
Acute Lymphoblastic Leukemia
04/26
04/26
SIOP-EP-II, NCT02265770 / 2013-002766-39: An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma

Recruiting
2/3
536
Europe, RoW
16 weeks of VEC + CDDP, Vincristine, Etoposide, Cyclophosphamide, Cisplatin, VEC + HD-MTX, Methotrexate, Chemotherapy + Valproate, Carboplatin, Valproate, Conformal radiotherapy, VEC, Chemotherapy, conformal radiotherapy +/- boost
Centre Leon Berard
Childhood Ependymoma
06/28
08/31
RETINO2018, NCT04681417 / 2019-005039-94: Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome

Recruiting
2/3
225
Europe
Melphalan or Melphalan + Topotecan, Alkeran, Topotecan Accord; Topotecan Hospira chemotherapy, etoposide, carboplatin and vincristine or local ophthalmological treatment without IV chemotherapy, etoposide, carboplatin and vincristine chemotherapy, Carboplatin administered on Day 1, platinum-based chemotherapy, Thermotherapy (local treatment), Thermotherapy after carboplatin administered on Day 1, Cryotherapy (local treatment), Iodine-125 plaques (local treatment), Intravitreal Melphalan chemotherapy injections (local treatment)
Institut Curie, Fondation Rothschild Paris
Retinoblastoma
01/35
01/36
RETINO2011, NCT02866136: Conservative Treatments of Retinoblastoma

Active, not recruiting
2
133
Europe
VP16, carboplatin, etoposide, vepesid, chemotherapy, Melphalan, Alkeran, chemotherapy, VP16, carboplatin, vincristin, etoposide, vepesid, leurocristine, Oncovin, chemotherapy, Carboplatin + laser day 1 (chemothermotherapy), Carbo-laser, platinum-based chemotherapy, Laser (local treatment), Laser diode, cryoapplication (local treatment), I125 radioactive plaques (local treatment), intravitreal Melphalan (local treatment)
Institut Curie, Fondation Rothschild Paris
Retinoblastoma, Children, Retinal Neoplasm
01/23
09/35
NCT02870907 / 2009-016448-38: Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009)

Recruiting
2
185
Europe
Observation, Low risk group, Etoposide, Intermediate risk sub group 1, Vincristine, Intermediate risk sub group 2, Orbital irradiation, High risk group, Carboplatin, Cyclophosphamide, Thiotepa, Cytapheresis, Peripheral bood stem cell transplantation
Institut Curie
Retinoblastoma
03/30
09/30
MILA, NCT05792007: Study of the Medullary Microenvironment in Acute Childhood Leukemia

Recruiting
N/A
40
Europe
Biological sampling in patients, Biological sampling in control patients
University Hospital, Tours
Acute Lymphoid Leukemia, Acute Myeloid Leukemia in Children
10/26
10/28
MICCHADO, NCT03496402: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults

Active, not recruiting
N/A
600
Europe
Sampling on blood, bone marrow and cerebrospinal fluid
Institut Curie
Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma Family of Tumors, Osteosarcoma, Leukemia, Central Nervous System Tumor
04/27
08/27
Machet, Laurent
RITUX-MMP, NCT03295383: Randomized Clinical Trial Comparing the Safety and Efficacy of Rituximab Versus Oral Cyclophosphamide in Severe Forms of Mucous Membrane Pemphigoid

Recruiting
3
130
Europe
Rituximab 1g IV, Cyclophosphamide 50Mg Oral Tablet, Placebo of Rituximab, Placebo Oral Tablet
University Hospital, Rouen
Severe Forms of Mucous Membrane Pemphigoid
11/22
11/23
CANNABITCH, NCT06435299: Efficacy and Tolerance of Cannabidiol in Patients with Severe Pruritus: a Multicenter, Double-blind, Randomized, Placebo-controlled Study

Not yet recruiting
3
218
Europe
Cannabis oil, Placebo
University Hospital, Brest
Pruritus
07/27
07/27
TELLOMAK, NCT03902184 / 2018-003969-33: IPH4102 Alone or in Combination With Chemotherapy in Patients With Advanced T Cell Lymphoma

Checkmark Preliminary efficacy data from TELLOMAK trial for Sezary syndrome at ASH 2022
Dec 2022 - Dec 2022: Preliminary efficacy data from TELLOMAK trial for Sezary syndrome at ASH 2022
Checkmark Data from stage 2 cohort of TELLOMAK trial for mycosis fungoides
Sep 2022 - Sep 2022: Data from stage 2 cohort of TELLOMAK trial for mycosis fungoides
Checkmark Preliminary efficacy data from stage 1 of TELLOMAK trial for mycosis fungoides at ICML 2021
More
Active, not recruiting
2
170
Europe, US
IPH4102, lacutamab
Innate Pharma
Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides/Sezary Syndrome
10/23
01/26
EBIN, NCT03235245 / 2017-002887-42: Immunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and Binimetinib

Active, not recruiting
2
271
Europe
Nivolumab + Ipilimumab, Encorafenib + Binimetinib
European Organisation for Research and Treatment of Cancer - EORTC
Unresectable Stage III Melanoma, Stage IV Melanoma
10/23
01/27
BIOVAS, NCT05565885: Search for BIO Diagnostic and Prognostic Markers in Adult VAScularitis

Recruiting
N/A
225
Europe
Sampling
University Hospital, Tours
Vasculitis
12/37
12/37
CARADERM, NCT03210935: French National Database of Rare Dermatological Cancers

Recruiting
N/A
9000
Europe
University Hospital, Lille
Adnexal Tumor of Skin, Merkel Cell Carcinoma, Advanced Basal Cell Carcinoma Requiring Systemic Treatment
12/25
12/25
MAILLOT, François
BIOVAS, NCT05565885: Search for BIO Diagnostic and Prognostic Markers in Adult VAScularitis

Recruiting
N/A
225
Europe
Sampling
University Hospital, Tours
Vasculitis
12/37
12/37
MATAC, NCT06444477: Molecular Analysis of Thrombocytopenia and Cancer (): Investigating Antigenic Mimicry Between Platelets and Tumor Cells in Patients With Immune Thrombocytopenia (ITP) Associated With Cancer

Not yet recruiting
N/A
70
Europe
ITP and cancer
University Hospital, Bordeaux
Immune Thrombocytopenia, Immune Thrombocytopenic Purpura, Neoplasms, Cancer
12/24
12/24
ImPACT, NCT03379207: Innate Immune Response During Community Acquired Pneumonia

Recruiting
N/A
350
Europe
Blood samples, Tracheal Aspirates, Surplus of Broncho-alveolar lavage fluid
University Hospital, Tours
Community-acquired Pneumonia, Acute Respiratory Distress Syndrome, Innate Immunity
09/24
03/25
Maruani, Annabel
BRAVE-AA-PEDS, NCT05723198: A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

Recruiting
3
595
Europe, Canada, Japan, US, RoW
Baricitinib, LY3009104, Placebo
Eli Lilly and Company
Areata Alopecia, Alopecia, Hypotrichosis, Hair Diseases, Skin Diseases, Pathological Conditions, Anatomical
09/24
08/29
TOPGUN, NCT04128722: TOPical Sirolimus in linGUal Microcystic Lymphatic Malformation -

Recruiting
2
12
Europe
Sirolimus Oral Liquid Product 1mg/mL, Experimental treatment
University Hospital, Tours
Lingual Microcystic Lymphatic Malformations
02/25
07/25
SESAM, NCT05577754: Assessment of the Efficacy and Safety of Alpelisib (BYL719) in Pediatric and Adult Patients with Megalencephaly-CApillary Malformation Polymicrogyria Syndrome (MCAP)

Recruiting
2
20
Europe
Alpelisib (BYL719), Matching placebo, Optional lumbar puncture + blood sample
Centre Hospitalier Universitaire Dijon, Novartis Pharmaceuticals
Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)
03/27
03/27
NCT04451902: COVID-19 and Rare Skin Diseases European Observational Study During an Epidemic

Recruiting
N/A
80
Europe, RoW
Imagine Institute
Rare Diseases
04/22
12/22
MARKS, NCT06103903: Measure of Acceptance of chRonic Visible sKin conditionS

Recruiting
N/A
250
Europe
Questionnaire
University Hospital, Tours, INSERM UMR 1246 SPHERE
Acceptance of Visible Chronic Dermatological Disease, Disease Acceptance, Psychological Well-Being, Social Segregation
12/25
12/25
FARD, NCT05954416: (RaDiCo Cohort) (RaDiCo-)

Recruiting
N/A
900
Europe
Institut National de la Santé Et de la Recherche Médicale, France
Inherited Epidermolysis Bullosa, Ichthyosis, Ectodermal Dysplasia, Incontinentia Pigmenti, Neurofibromatosis Type 1, Albinism, Pemphigus, Mucous Membrane Pemphigoid, Palmoplantar Keratoderma
03/27
03/27
COVER, NCT04352036: Constitution of a Prospective Cohort of Patients With Acute Suppurative Hidrosadenitis Followed in the Great West: the Cohort (Verneuil Cohort)

Recruiting
N/A
465
Europe
no interventional study
Nantes University Hospital
Acute Hidrosadenitis
02/30
02/30
Beaufils, Emilie
PAPPEL, NCT06263868: First Observatory of Precocious Puberty.

Not yet recruiting
N/A
3360
Europe
Hospices Civils de Lyon
Puberty, Precocious
03/28
03/28
Santiago-Ribeiro, Maria-Joao
NCT04265209 / 2019-000247-27: [18F] LBT-999 PET Compared to [123I]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tremor

Recruiting
3
152
Europe
SPECT, PET
Zionexa
Parkinson Disease, Essential Tremor
09/24
12/24
InflaDep, NCT03314155: Cerebral Neuroinflammation During Major Depressive Episode

Recruiting
N/A
60
Europe
Cerebral neuroinflammation evaluation
University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France
Depressive Disorder
01/24
01/24
GISSOT, Valerie
PINK-AD, NCT04570761: Effects of Auditory Brain Stimulation by "Pink Noise" on Memory Capacities in Alzheimer's Disease: Proof of Concept Study

Recruiting
N/A
30
Europe
Dreem headband
University Hospital, Tours
Alzheimer's Disease (AD)
03/24
03/24
ZEMMOURA, Ilyess
StrateGlio, NCT03663725 / 2018-000410-38: Treatment Intensification With Temozolomide in Adults With a Glioblastoma

Recruiting
3
486
Europe
Intensified protocol, Stupp protocol
Centre Oscar Lambret, Association de Neuro-Oncologues d'Expression Francaise, Erasme University Hospital
Glioblastoma
05/25
11/27
POLO, NCT04702581: A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than Surgery

Recruiting
3
280
Europe
PCV chemotherapy, Radiotherapy and PCV chemotherapy
Hospices Civils de Lyon
Oligodendroglioma, Low-grade Oligodendroglioma, 1p19q Codeletion
12/30
12/30
Stephan, Jean-Louis
RETINO2018, NCT04681417 / 2019-005039-94: Ocular Conservative Treatment for Retinoblastoma : Efficacy of the New Management Strategies and Visual Outcome

Recruiting
2/3
225
Europe
Melphalan or Melphalan + Topotecan, Alkeran, Topotecan Accord; Topotecan Hospira chemotherapy, etoposide, carboplatin and vincristine or local ophthalmological treatment without IV chemotherapy, etoposide, carboplatin and vincristine chemotherapy, Carboplatin administered on Day 1, platinum-based chemotherapy, Thermotherapy (local treatment), Thermotherapy after carboplatin administered on Day 1, Cryotherapy (local treatment), Iodine-125 plaques (local treatment), Intravitreal Melphalan chemotherapy injections (local treatment)
Institut Curie, Fondation Rothschild Paris
Retinoblastoma
01/35
01/36
RETINO2011, NCT02866136: Conservative Treatments of Retinoblastoma

Active, not recruiting
2
133
Europe
VP16, carboplatin, etoposide, vepesid, chemotherapy, Melphalan, Alkeran, chemotherapy, VP16, carboplatin, vincristin, etoposide, vepesid, leurocristine, Oncovin, chemotherapy, Carboplatin + laser day 1 (chemothermotherapy), Carbo-laser, platinum-based chemotherapy, Laser (local treatment), Laser diode, cryoapplication (local treatment), I125 radioactive plaques (local treatment), intravitreal Melphalan (local treatment)
Institut Curie, Fondation Rothschild Paris
Retinoblastoma, Children, Retinal Neoplasm
01/23
09/35
NCT02870907 / 2009-016448-38: Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated (RB SFCE 2009)

Recruiting
2
185
Europe
Observation, Low risk group, Etoposide, Intermediate risk sub group 1, Vincristine, Intermediate risk sub group 2, Orbital irradiation, High risk group, Carboplatin, Cyclophosphamide, Thiotepa, Cytapheresis, Peripheral bood stem cell transplantation
Institut Curie
Retinoblastoma
03/30
09/30
X-MAIDReg, NCT06278337: X-linked Moesin Associated Immunodeficiency

Recruiting
N/A
16
Europe, Japan, US, RoW
genetic restrospective study
Institut National de la Santé Et de la Recherche Médicale, France
Immune Deficiency, Autoimmune Diseases, Infections, Diagnosis
08/26
01/27
EXOCARE, NCT03472807: EXOme Rare Cancers in Children

Recruiting
N/A
300
Europe, RoW
Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available
University Hospital, Angers
Predisposition, Genetic, Cancer Childhood, Development Delay
02/25
08/25
Desmidt, Thomas
NCT03454646: Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL)

Not yet recruiting
4
1205
Europe
cholinesterase inhibitors (CI) (donepezil, galantamine or rivastigmine)
University Hospital, Bordeaux
Alzheimer Disease, Cholinesterase Inhibitors
04/27
09/27
TRAILBLAZER-ALZ 5, NCT05508789: A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease

Recruiting
3
1500
Europe, RoW
Donanemab, (LY3002813), Placebo
Eli Lilly and Company
Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders
04/27
04/27
PROTO-BRAIN, NCT05007028: Nitrous Oxide for Late-Life Depression -

Recruiting
N/A
60
Europe
EMONO, Medical Air
University Hospital, Tours
Late-Life Depression, Resistant Depression, Treatment
12/24
12/24
InflaDep, NCT03314155: Cerebral Neuroinflammation During Major Depressive Episode

Recruiting
N/A
60
Europe
Cerebral neuroinflammation evaluation
University Hospital, Toulouse, Institut National de la Santé Et de la Recherche Médicale, France
Depressive Disorder
01/24
01/24
COG-PULCE, NCT05129150: Cognitive Disorders and Brain Pulse

Recruiting
N/A
300
Europe
Ultrasound examination
University Hospital, Tours
Neurocognitive Disorders
03/26
03/31
TAUVERON, Valerie
ACTIODERM, NCT04252690: Physiological Study to Assess Mechanism of Action of MOBIDERM® in Lower-limb Lymphedema Patients

Completed
N/A
9
Europe
MOBIDERM® autofit : auto-adjustable compression stocking
Thuasne, University Hospital, Tours, Delta Consultants
Lymphedema of Leg, Lymphedema Congenital, Lymphedema Primary, Lymphedema, Secondary
06/22
06/22
LYMphoNIGHT, NCT04203069: Auto-Adjustable MOBIDERM® Autofit NIGHT-time Compression Armsleeve in the Upper Limb LYMphedema in Maintenance Phase

Completed
N/A
63
Europe, RoW
Control group : Day-time compression sleeve, Intervention group : Day-time compression sleeve and Night-time MOBIDERM® Autofit
Thuasne, International Clinical Trials Association
Lymphedema of Upper Arm
12/23
09/24
D'ALTEROCHE, Louis
GAVAPROSEC, NCT03705078: "Early TIPS" Versus Glue Obliteration to Prevent Rebleeding From Gastric Varices

Completed
N/A
104
Europe
Transjugular Portosytemic Shunt (TIPS), glue obliteration
Centre Hospitalier Universitaire de Besancon
Bleeding Gastric Varices, Cirrhosis
03/23
02/24
BuleDelta, NCT04166266: National Cohort of Patients Co-infected with Hepatitis B and Delta Viruses

Recruiting
N/A
800
Europe
Blood draw for the laboratory assessment
ANRS, Emerging Infectious Diseases
Hepatitis D, Chronic, Hepatitis B, Chronic
12/27
06/28
MORINIERE, Sylvain
PATHOS, NCT02215265 / 2014-003392-32: Post-operative Adjuvant Treatment for HPV-positive Tumours

Recruiting
3
1100
Europe, US, RoW
Cisplatin, Postoperative radiotherapy
Lisette Nixon, UNICANCER, AdventHealth, University of Leipzig, Princess Alexandra Hospital, Brisbane, Australia, Stanford University
Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer
10/26
04/27
TORPHYNX, NCT04224389: IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas

Recruiting
N/A
150
Europe
transoral resection, IMRT
Gustave Roussy, Cancer Campus, Grand Paris
Squamous Cell Carcinoma
06/29
06/29
Eph-L, NCT06014710: Modelling of Pharyngeal Laryngeal Effectiveness

Recruiting
N/A
520
Europe
Swallowing evaluation
University Hospital, Toulouse, National Research Agency, France, Institut de Recherche en Informatique de Toulouse (IRIT), Laboratoire parole et langage, Swallis Medical
Swallowing Disorders
12/24
06/25
SALAME, Ephrem
HALT, NCT06535945: Influence of Human Albumin Supplementation on Kidney Dysfunction After Liver Transplantation

Not yet recruiting
4
400
Europe
Albumin administration
Rennes University Hospital, Ministry of Health, France
Liver Transplantation, Acute Kidney Injury
03/28
04/28
Ta-Len-Tra, NCT05901194: Lenvatinib Treatment in Waiting List of Liver Transplantation After TACE Failure in Patients With Hepatocellular Carcinoma

Not yet recruiting
1/2
25
Europe
Lenvatinib
Assistance Publique - Hôpitaux de Paris, Laboratoire EISAI
Hepatocellular Carcinoma Non-resectable
12/26
07/27
BIOSUPORT, NCT03997253: Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management

Recruiting
N/A
430
Europe
blood and urine samples
University Hospital, Limoges, University Hospital Federation FHU SUPORT
Organ Transplantation
02/25
11/25
Clinique, Centre d'Investigation
NCT06035367: SKAMo-2: the Real-life Test of Continuous Photoacoustic Signal by Neogly in Patients With Type I Diabetes

Recruiting
N/A
10
Europe
Non-invasive continuous monitoring device to record photoacoustic signal
Eclypia
Diabetes
10/23
10/23
Clementy, Nicolas
CANVAS-R, NCT06159764: National Registry of Cardioneuroablation in Recurrent Reflex Syncope

Recruiting
N/A
50
Europe
Cardioneuroablation
University Hospital, Bordeaux
Syncope, Vasovagal, Bradycardia, Heart Arrest
01/26
01/26
NCT04735016: DiamondTemp Global Registry

Recruiting
N/A
1000
Europe, RoW
DiamondTemp™ Ablation System
Medtronic Cardiac Rhythm and Heart Failure
Arrhythmia
03/31
03/31
ANIMATION, NCT04347109: cArdiac Non Invasive MApping in resynchronizaTION

Suspended
N/A
50
Europe
Non invasive epicardial mapping, Cardio Insight system, ECG imaging
University Hospital, Tours
Cardiac Resynchronization Therapy
12/25
12/25
CROSS-LEFT-AF, NCT05162716: Cardiac ResynchrOniSation Via Stimulation of the LEFT Bundle in AF Patients.

Recruiting
N/A
50
Europe
Single-chamber pacemaker implantation with left bundle branch area pacing, Atrioventricular junction ablation
Nicolas Clementy, MD, PhD, Dr Arnaud BISSON
Pacing-Induced Cardiomyopathy
05/22
10/22
Pierre, Bertrand
NCT04619888: HeartLogic France Study: Heart Failure Patients Managed With the HeartLogic Algorithm

Recruiting
N/A
310
Europe
HeartLogic
Poitiers University Hospital
Heart Failure
07/23
07/23
ASTRAL-4LV, NCT04463641: Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy

Active, not recruiting
N/A
92
Europe
Implantation of the Axone 4LV Lead
MicroPort CRM
Heart Failure, Cardiac Resynchronization Therapy
06/24
12/27
 

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