Shen, Feng |
| Not yet recruiting | 4 | 336 | RoW | Danning Tablet, Biliflow (NPN 80073325, manufactured by Shanghai Hutchison Pharmaceuticals Limited) | Eastern Hepatobiliary Surgery Hospital | Polyps Gallbladder | 08/24 | 11/24 | | |
NCT05862337: Anlotinib Hydrochloride Capsules Combined With Penpulimab Injection for the Treatment of Hepatocellular Carcinoma at High Risk of Recurrence. |
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| Recruiting | 3 | 480 | RoW | Anlotinib hydrochloride capsules, Penpulimab injection, Anlotinib hydrochloride capsules -matching placebo, Penpulimab injection -matching placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Hepatocellular Carcinoma | 08/24 | 12/26 | | |
| Not yet recruiting | 3 | 165 | RoW | TQB3454 tablets, TQB3454 tablets matching placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Biliary Carcinoma | 12/26 | 12/26 | | |
NCT05913336: A Study of Remimazolam Tosilate for Prolonged Sedation in the ICU |
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| Recruiting | 1/2 | 20 | RoW | Remimazolam Tosilate | Jiangsu HengRui Medicine Co., Ltd. | Sedation in the ICU | 11/23 | 11/23 | | |
| Recruiting | 1/2 | 103 | RoW | TQB2102 for injection | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | Biliary Tract Cancer | 05/25 | 12/25 | | |
NCT05292443: Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated Primary Liver Cancer |
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| Withdrawn | N/A | 300 | RoW | Observation | Geneplus-Beijing Co. Ltd., Eastern Hepatobiliary Surgery Hospital | Primary Liver Cancer, Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma, Combined Hepatocellular-cholangiocarcinoma | 03/23 | 03/23 | | |
Chen, Wei |
NCT06467513: To Investigate the Effect of Esketamine Hydrochloride on Pulmonary Complications |
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| Recruiting | 4 | 102 | RoW | Esketamine hydrochloride injection, 0.9% sodium chloride injection | Zhang XIao Mei | Heart Diseases, Heart Valve Diseases | 05/25 | 05/25 | | |
| Active, not recruiting | 4 | 800 | RoW | Sodium Oligomannate Capsules (GV-971) | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer Disease | 01/25 | 06/25 | | |
NCT06597201: Evaluate the Efficacy and Safety of Amino Acid (15) Peritoneal Dialysis Solution in Peritoneal Dialysis Patients with Malnutrition. |
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| Recruiting | 4 | 400 | RoW | amino acid (15) peritoneal dialysis solution, glucose peritoneal dialysis solution | Chengdu Qingshan Likang Pharmaceutical Co., Ltd | End Stage Renal Disease (ESRD) | 06/25 | 06/25 | | |
NCT05721404: Icodextrin Postpones the Shift of Low Dose to Full Dose Dialysis in the First Year of Incremental Peritoneal Dialysis |
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| Recruiting | 4 | 194 | RoW | Icodextrin Peritoneal Dialysis Solution, Hypertonic Dextrose solution | First Affiliated Hospital, Sun Yat-Sen University, Baxter Healthcare Corporation | Peritoneal Dialysis | 04/25 | 12/25 | | |
NCT04381143: ASPIrin in Reducing Events in Dialysis ( ASPIRED ) |
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| Recruiting | 4 | 9000 | RoW | Aspirin 100 mg Oral Tablet, Matching Placebo | Guangdong Provincial People's Hospital, The George Institute | CKD (Chronic Kidney Disease) Stage 5D | 09/26 | 12/26 | | |
NCT06720233: Efficacy and Safety Study of SAL-0951 in the Treatment of Renal Anemia in Patients Receiving Peritoneal Dialysis |
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| Completed | 3 | 37 | RoW | SAL-0951 tablets, SAL-0951 group | Shenzhen Salubris Pharmaceuticals Co., Ltd. | Anemia | 10/24 | 10/24 | | |
NCT05629390: Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA Study |
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| Completed | 3 | 163 | RoW | Lotilaner, TP-03, S-Misoxam, Vehicle Control | LianBio LLC | Blepharitis | 09/23 | 04/24 | | |
NCT06720025: Study of SAL-0951 Compared to Recombinant Human Erythropoietin in Anemic Patients Receiving Maintenance Hemodialysis |
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| Completed | 3 | 100 | RoW | SAL-0951 tablets, SAL-0951 group, rHuEPO injection, rHuEPO group | Shenzhen Salubris Pharmaceuticals Co., Ltd. | Anemia | 06/24 | 06/24 | | |
| Recruiting | 3 | 450 | Europe, US, RoW | LY3650150, Placebo, Standard therapy for INCS | Eli Lilly and Company | Perennial Allergic Rhinitis (PAR) | 10/25 | 02/27 | | |
NCT04370925: Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis |
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| Recruiting | 3 | 688 | RoW | Radical colectomy, HIPEC, Systemic chemotherapy | Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Nanfang Hospital of Southern Medical University, Sun Yat-sen University, Sixth Affiliated Hospital, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangdong Provincial People's Hospital, Meizhou People's Hospital, First People's Hospital of Foshan, Shantou Central Hospital, Jiangmen Central Hospital, Shenzhen Second People's Hospital, Zhongshan People's Hospital, Guangdong, China, ZhuHai Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing Hospital, Beijing Cancer Hospital, Peking University People's Hospital, Fudan University, The Second Affiliated Hospital of Chongqing Medical University, Chongqing University Cancer Hospital, First Affiliated Hospital of Chongqing Medical University, Second Affiliated Hospital, School of Medicine, Zhejiang University, Wuhan Union Hospital, China, Renmin Hospital of Wuhan University, Wuhan University, Sichuan Provincial People's Hospital, West China Hospital, The People's Hospital of Leshan, People’s Hospital of Deyang City, Hebei Medical University Fourth Hospital, The First Affiliated Hospital of Nanchang University, The Affiliated Hospital Of Southwest Medical University, The Affiliated Hospital of Xuzhou Medical University, People's Hospital of Guangxi, The Third People's Hospital of Chengdu, The Affiliated Tumor Hospital of Guangxi Medical University | Colorectal Cancer | 04/24 | 04/26 | | |
| Recruiting | 3 | 1200 | Europe, Canada, Japan, US, RoW | Remternetug, LY3372993, Placebo | Eli Lilly and Company | Alzheimer's Disease | 04/29 | 10/30 | | |
NCT06717152: Efficacy and Safety of SJP-0132 Eye Drops in Chinese Patients With Dry Eye Disease |
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| Recruiting | 3 | 400 | RoW | SJP-0132, Placebo | Senju Pharmaceutical Science & Technology (Beijing) Co., Ltd., Senju Pharmaceutical Co., Ltd. | Dry Eye | 07/25 | 08/25 | | |
| Recruiting | 3 | 400 | Europe, Canada, Japan, US, RoW | tucatinib, TUKYSA, ONT-380, ARRY-380, PF-07265792, trastuzumab, Herceptin, bevacizumab, Avastin, cetuximab, Erbitux, oxaliplatin, leucovorin, levoleucovorin, fluorouracil | Seagen Inc., Merck Sharp & Dohme LLC | Colorectal Neoplasms | 08/25 | 04/28 | | |
| Recruiting | 3 | 1500 | Europe, RoW | Donanemab, (LY3002813), Placebo | Eli Lilly and Company | Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders | 04/27 | 04/27 | | |
| Recruiting | 2/3 | 230 | Canada, US | MN-166, ibudilast, placebo | MediciNova | Amyotrophic Lateral Sclerosis | 12/25 | 12/26 | | |
NCT06470191: A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy. |
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| Recruiting | 2/3 | 216 | RoW | B007, Cyclosporin Capsules | Shanghai Jiaolian Drug Research and Development Co., Ltd, Shanghai Pharmaceuticals Holding Co., Ltd | Primary Membranous Nephropathy | 12/26 | 12/26 | | |
NCT05811442: Study of 50561 in Patients With Mild or Moderate Alzheimer's Disease |
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| Recruiting | 2a | 60 | RoW | 50561 high dose, 50561 low dose, Placebo | Beijing Joekai Biotechnology LLC | Alzheimer's Disease | 05/24 | 06/24 | | |
NCT06435182: Study of OT202 in Treating Moderate to Severe Dry Eye |
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| Completed | 2 | 213 | RoW | OT202 conc 0.5%, Investigational product, OT202 conc 0.1%, Placebo | Ocumension Therapeutics (Shanghai) Co., Ltd | Dry Eye | 01/24 | 01/24 | | |
NCT05810961: A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients with Primary Membranous Nephropathy (ZL-1103-014) |
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| Terminated | 2 | 8 | RoW | efgartigimod IV, placebo | argenx, Zai Lab Pty. Ltd. | Membranous Nephropathy | 08/24 | 08/24 | | |
NCT05810948: A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients with Lupus Nephritis (ZL-1103-013) |
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| Recruiting | 2 | 60 | RoW | efgartigimod IV, Placebo | argenx, Zai Lab (Shanghai) Co., Ltd. | Lupus Nephritis | 07/25 | 09/25 | | |
NCT05593575: Efficacy and Safety of SPH3127 Tablets on Treating the Diabetic Kidney Disease |
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| Recruiting | 2 | 320 | RoW | SPH3127+SPH3127matching placebo+valsartan matching placebo, SPH3127+valsartan matching placebo, SPH3127 matching placebo+valsartan | Shanghai Pharmaceuticals Holding Co., Ltd | Diabetic Kidney Disease | 06/25 | 06/25 | | |
NICRRBTC, NCT06699459: Irinotecan Liposomes +5-FU/LV Versus Capecitabine in Patients of Recurrence After Resection of Resectable BTC |
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| Not yet recruiting | 2 | 76 | RoW | Irinotecan Liposome, Irinotecan Liposome+LV/5-FU, Capecitabine | Sir Run Run Shaw Hospital, Zhejiang Cancer Hospital, RenJi Hospital, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Fujian Provincial Hospital, Ningbo No. 1 Hospital, Shaoxing People's Hospital, Southern Medical University, China, First Affiliated Hospital, Sun Yat-Sen University | Biliary Tract Carcinoma | 11/26 | 11/26 | | |
NCT06760182: Clinical Trial of TQH2722 Injection in Patients With Seasonal Allergic Rhinitis |
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| Not yet recruiting | 2 | 168 | RoW | TQH2722 injection, TQH2722 Placebo | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | Seasonal Allergic Rhinitis | 06/25 | 08/25 | | |
MAGIC, NCT05053802: Efficiency and Safety of Microwave Ablation Plus Immune Checkpoint Inhibitor for Patients With Multiple Primary Lung Cancer: A Open, Multi-center, Phase II Clinical Trial |
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| Recruiting | 2 | 146 | RoW | Microwave ablation plus Camrelizumab, Microwave ablation | Shanghai Pulmonary Hospital, Shanghai, China | Multiple Primary Lung Cancer | 09/25 | 09/27 | | |
| Suspended | 2 | 279 | Europe, US, RoW | zetomipzomib, KZR-616, placebo, matching placebo | Kezar Life Sciences, Inc. | Lupus Nephritis | 05/26 | 07/26 | | |
NCT06474416: A Study of the Safety, Tolerability and Prelinminary Efficacy of BD111 in Herpes Simplex Virus Type I Stromal Keratitis |
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| Recruiting | 1 | 16 | RoW | BD111 Injection (Investigative New Drug), BD111 Lentivirus-like particles, HSV-1-erasing lentiviral particles, HELP, Triple-drugs therapy of HSV-1 stromal keratitis, Ganciclovir Ophthalmic Gel, Valacyclovir Hydrochloride Tablets, Prednisolone Acetate Ophthalmic Suspension | Shanghai BDgene Co., Ltd. | Herpes Simplex Virus Type I Stromal Keratitis | 09/25 | 09/25 | | |
NCT05633459: A Study Evaluating the Safety and Tolerability of QRL-201 in ALS |
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| Recruiting | 1 | 64 | Europe, Canada | Multiple ascending doses of QRL-201, Multiple ascending doses of Placebo, QRL-201, Placebo | QurAlis Corporation | Amyotrophic Lateral Sclerosis | 08/26 | 08/26 | | |
| Recruiting | N/A | 5000 | RoW | No Intervention: Observational Cohort | First Affiliated Hospital, Sun Yat-Sen University | Lupus Nephritis (LN) | 12/50 | 12/50 | | |
| Terminated | N/A | 1706 | RoW | SpO2 directed oxygen therapy | Wuhan Union Hospital, China, Wu Jieping Medical Foundation | Critical Illness | 05/22 | 05/22 | | |
NCT05311462: An Observational Cohort Study to Obese Patients With Weight Cycling |
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| Active, not recruiting | N/A | 180 | RoW | | Peking Union Medical College Hospital | Weight Cycling, Obesity | 01/25 | 12/28 | | |
NCT05570435: Efficacy of Milk Product Supplemented With Bioactives in Lowering Post Meal Glucose Response |
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| Completed | N/A | 31 | RoW | Blood collection | Société des Produits Nestlé (SPN), Peking Union Medical College Hospital | Healthy, PreDiabetes, Adult, Asian | 03/23 | 03/23 | | |
NCT05857917: Virtual Reality for for Pain and Anxiety Distraction Strategy on Peritoneal Catheter Insertion |
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| Recruiting | N/A | 70 | RoW | Virtual Reality | First Affiliated Hospital, Sun Yat-Sen University | Renal Function Disorder | 10/23 | 10/23 | | |
NCT05859165: To Evaluate Clinical Efficacy and Safety of Diabetes-Specific Formula (Nutren Diabetes) |
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| Recruiting | N/A | 250 | RoW | Nutren Diabetes, Fresubin Diabetes | Société des Produits Nestlé (SPN), Nestle Health Science | Diabetes Mellitus | 12/24 | 06/25 | | |
| Recruiting | N/A | 70 | US | Administration of the ASk Questions in GYnecologic Oncology (ASQ-GYO) Question Prompt List | Ira Winer | Ovarian Cancer, Endometrial Cancer, Cervical Cancer, Vulvar Cancer, Vaginal Cancer, Gestational Trophoblastic Disease | 05/26 | 05/27 | | |
NCT05651321: Studies on the Impact of Taste-aware Intelligent Analysis of Oral Nutritional Supplements |
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| Recruiting | N/A | 108 | RoW | Samples materials of basic taste stimuli and enteral nutrition preparations | Peking Union Medical College Hospital | Cancer- and Cancer Treatment-Related Conditions, Stroke | 06/24 | 12/24 | | |
WHIP, NCT06545721: Weight Cycling on Hyperandrogenemia and Insulin Resistance in Polycystic Ovary Syndrome |
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| Not yet recruiting | N/A | 425 | RoW | Adjusting dietary structure + exercise + behavioral intervention | Peking Union Medical College Hospital | Polycystic Ovary Syndrome | 08/25 | 08/26 | | |
| Active, not recruiting | N/A | 11737 | US | | Tulane University, National Heart, Lung, and Blood Institute (NHLBI), National Institute on Aging (NIA), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute of Environmental Health Sciences (NIEHS) | Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Coronary Disease, Hypertension | 11/29 | 11/29 | | |
NCT05190848: Correlation of Microbiome and Metabonomics With IgA Nephropathy |
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| Recruiting | N/A | 600 | RoW | | Guangdong Provincial People's Hospital | IgA Nephropathy | 12/24 | 12/24 | | |
NCT06793475: Aponermin-Based Bridging Therapy Prior to CAR-T Infusion in Relapsed/Refractory Multiple Myeloma Patients With Extramedullary Disease |
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| Recruiting | N/A | 20 | RoW | anti-BCMA/GPRC5D bispecific CAR-T, Apornemin, Carfilzomib, Thalidomide, Dexamethasone | Institute of Hematology & Blood Diseases Hospital, China | Extramedullary Multiple Myeloma | 06/26 | 12/26 | | |
| Not yet recruiting | N/A | 2000 | RoW | | China-Japan Friendship Hospital, Second Affiliated Hospital of Xi'an Jiaotong University, First Hospital of China Medical University, Henan Provincial People's Hospital, Second Xiangya Hospital of Central South University, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Sichuan University, Ruijin Hospital Affiliated to Shanghai Jiao Tong University, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China | Chronic Obstructive Pulmonary Disease (COPD), Asthma, Bronchiectasis | 07/28 | 07/28 | | |
NCT04212494: Thrombus Aspiration in STEMI Patients With High Thrombus Burden |
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| Recruiting | N/A | 3838 | RoW | Thrombus aspiration, PCI Alone | Guangdong Provincial People's Hospital, Zhongshan People's Hospital, Guangdong, China, Kaiping Central Hospital, The Second Affiliated Hospital of Shantou University Medical College, The Third Xiangya Hospital of Central South University, Sihui City People's Hospital, Shenzhen Baoan District Shiyan People's Hospital, People's Hospital of Nanxiong County, Yuebei People's Hospital, Weifang Medical University, Wuzhou Gongren Hospital, Dafeng Hospital of Chaoyang District in Shantou City, Shenzhen Baoan People's Hospital, Dongguan People's Hospital, Yangchun People's Hospital, Taishan People's Hospital, The Second People's Hospital of Foshan, Guangzhou Hospital of integrated Traditional and West Medicine, Guangning People's Hospital, Foshan Sanshui District People's Hospital, Qingyuan People's Hospital, Luhe County People's Hospital, People's Hospital of Xinjiang Uygur Autonomous Region, The Fourth People's Hospital of Chenzhou, People's Hospital of Dapu County, Shenzhen People's Hospital, Heyuan people's Hospital, Huaiji People's Hospital, People's Hospital of Yingde City, Qingyuan Hospital of Traditional Chinese Medicine Affiliated To Guangzhou University of Traditional Chinese Medicine, Zhongshan Hospital Of Traditional Chinese Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Lianzhou People's Hospital, Lianping Xian Ren Ming Yi Yuan, Guangxi Zhuang Autonomous Region Nationalities Hospital, Liuzhou Municipal Liutie Central Hospital, Chen Zhou 3RD People's Hospital, Longgang District Central Hospital of Shenzhen, The Affiliated Shunde Hospital of Jinan University, Shenzhen Longhua District Central Hospital, Shantou Central Hospital, Tongxiang First People's Hospital, Bobai County People's Hospital, Guangxi, Meizhou Traditional Chinese Medicine Hospital, The Third Affiliated Hospital of Sun Yat-Sen University, Yuedong Hospital, Shenzhen Third People's Hospital, Yangjiang People's Hospital, Jiangmen Central Hospital, Eighth Affiliated Hospital, Sun Yat-sen University, The First People's Hospital of Kashgar Erea, First People's Hospital of Foshan, Zhaoqing Gaoyao People's Hospital, People's Hospital of Nanhai District, Foshan, The Second Affiliated Hospital of Dalian Medical University, Nanning Second People's Hospital, The Second People's Hospital of Nanhai District of Foshan, Shangyou People's Hospital | ST-segment Elevation Myocardial Infarction (STEMI) | 08/25 | 02/26 | | |
NCT05754866: Transbronchial Lung Cryobiopsy in Undiagnosed Acute Respiratory Failure |
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| Recruiting | N/A | 100 | RoW | Transbronchial lung cryobiopsy, Transbronchial lung biopsy | China-Japan Friendship Hospital | Acute Respiratory Failure, Acute Respiratory Distress Syndrome | 11/25 | 11/25 | | |
NCT05188885: A Real World, Multi-centric, Observational Registry Study of Chronic Kidney Diseases |
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| Recruiting | N/A | 90000 | RoW | | Guangdong Provincial People's Hospital | Chronic Kidney Disease | 12/26 | 12/28 | | |
Wang, Jian |
NCT04275323: Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1) |
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| Completed | 3 | 302 | RoW | NL003, HGF plasmid, pCK-HGF-X7, Normal Saline, Placebo | Beijing Northland Biotech. Co., Ltd. | Arterial Occlusive Disease, Ischemia, Ulcers, Peripheral Vascular Disease | 06/24 | 06/24 | | |
| Completed | 3 | 242 | RoW | NL003, HGF plasmid, pCK-HGF-X7, Normal Saline, Placebo | Beijing Northland Biotech. Co., Ltd. | Arterial Occlusive Disease, Ischemia, Ulcers, Peripheral Vascular Disease | 12/23 | 12/23 | | |
NCT05042375: A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer |
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| Recruiting | 3 | 450 | RoW | camrelizumab + famitinib, pembrolizumab, camrelizumab | Jiangsu HengRui Medicine Co., Ltd. | Non-small Cell Lung Cancer | 12/23 | 12/25 | | |
NCT04370925: Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis |
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| Recruiting | 3 | 688 | RoW | Radical colectomy, HIPEC, Systemic chemotherapy | Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Nanfang Hospital of Southern Medical University, Sun Yat-sen University, Sixth Affiliated Hospital, Sun Yat-sen University, First Affiliated Hospital, Sun Yat-Sen University, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangdong Provincial People's Hospital, Meizhou People's Hospital, First People's Hospital of Foshan, Shantou Central Hospital, Jiangmen Central Hospital, Shenzhen Second People's Hospital, Zhongshan People's Hospital, Guangdong, China, ZhuHai Hospital, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing Hospital, Beijing Cancer Hospital, Peking University People's Hospital, Fudan University, The Second Affiliated Hospital of Chongqing Medical University, Chongqing University Cancer Hospital, First Affiliated Hospital of Chongqing Medical University, Second Affiliated Hospital, School of Medicine, Zhejiang University, Wuhan Union Hospital, China, Renmin Hospital of Wuhan University, Wuhan University, Sichuan Provincial People's Hospital, West China Hospital, The People's Hospital of Leshan, People’s Hospital of Deyang City, Hebei Medical University Fourth Hospital, The First Affiliated Hospital of Nanchang University, The Affiliated Hospital Of Southwest Medical University, The Affiliated Hospital of Xuzhou Medical University, People's Hospital of Guangxi, The Third People's Hospital of Chengdu, The Affiliated Tumor Hospital of Guangxi Medical University | Colorectal Cancer | 04/24 | 04/26 | | |
RECAST-MT, NCT06559241: Remote Ischemic Conditioning for Acute Ischemic Stroke Treated with Mechanical Thrombectomy() |
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| Recruiting | 3 | 2105 | RoW | 14-day remote ischemic conditioning, 14-day RIC, 30-day remote ischemic conditioning, 30-day RIC, Endovascular thrombectomy, EVT, Best medical management | Capital Medical University | Acute Ischemic Stroke, Anterior Circulation Brain Infarction | 11/26 | 02/27 | | |
NCT06010693: A Study of Daridorexant in Chinese Patients With Insomnia Disorder |
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| Completed | 3 | 206 | RoW | Daridorexant, Placebo | Jiangsu Simcere Pharmaceutical Co., Ltd. | Insomnia Disorder | 04/24 | 05/24 | | |
NCT05180734: PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer |
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| Active, not recruiting | 3 | 878 | RoW | JS001/Placebo, Postoperative Adjuvant Chemotherapy, JS001/placebo combine with Postoperative Adjuvant Chemotherapy | Shanghai Junshi Bioscience Co., Ltd. | Gastric or Esophagogastric Junction Adenocarcinoma | 06/26 | 07/28 | | |
NCT05849727: A Clinical Study of TQH3821 Tablets in the Treatment of Treated Rheumatoid Arthritis |
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| Recruiting | 2 | 180 | RoW | TQH3821 tablets 200 mg, TQH3821 tablets matching placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Rheumatoid Arthritis | 06/24 | 12/24 | | |
iMHRT-LARC, NCT06599827: Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC |
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| Not yet recruiting | 2 | 54 | RoW | moderately hypofractionated radiotherapy, chemotherapy, immunotherapy, Total mesorectal excision (TME) surgery | Shanghai Zhongshan Hospital | Rectal Cancer | 09/26 | 09/29 | | |
NCT05115500: ADC Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of HER-2 Positive Advanced Solid Tumors(PRaG3.0) |
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| Not yet recruiting | 2 | 55 | RoW | ADC Combined With Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 | Second Affiliated Hospital of Soochow University | Carcinoma, Solid Tumor | 10/24 | 04/25 | | |
OP-TNT, NCT05563922: Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma |
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| Recruiting | 2 | 56 | RoW | Total Neoadjuvant Chemoradiotherapy, Total Neoadjuvant Treatment | Shanghai Zhongshan Hospital | Rectal Cancer | 08/25 | 08/27 | | |
NCT04528056: Pilot Study of the Safety and Efficacy of Sulfasalazine in Pulmonary Arterial Hypertension |
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| Recruiting | 1/2 | 80 | RoW | Sulfasalazine, Ambrisentan, Sulfasalazine's placebo, Ambrisentan's placebo | RenJi Hospital | Pulmonary Arterial Hypertension | 12/21 | 10/22 | | |
NCT04164485: Functional Collagen Scaffold for Laryngeal Soft Tissue Regeneration |
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| Recruiting | 1/2 | 60 | RoW | Functional collagen scaffold transplantation, Autologous adipose cell transplantation | Chinese Academy of Sciences, Peking Union Medical College | Glottic Insufficiency | 12/22 | 12/22 | | |
NCT03716011: A Postmarket Clinical Trial for EXCROSSAL Stent in CAD Patients With 3-month DAPT or 12-month DAPT |
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| Not yet recruiting | N/A | 2700 | RoW | EXCROSSAL | JW Medical Systems Ltd | Coronary Artery Disease | 12/21 | 12/25 | | |
NCT06239454: Interleaving Stimulation Improves Dyskinesia in Parkinson's Disease |
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| Recruiting | N/A | 50 | RoW | interleaving stimulation, empirical stimulation | Huashan Hospital, Medtronic | Parkinson's Disease | 12/24 | 02/25 | | |
NCT04363658: Efficacy Study of Hydrocephalus Surgery by Methods of Neuroelectrophysiology |
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| Recruiting | N/A | 65 | US | | Xiangya Hospital of Central South University | Hydrocephalus | 12/22 | 12/22 | | |
NCT06181773: Empowering Parents to Optimize Feeding Practices With Preschool Children (EPO Feeding Program) |
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| Completed | N/A | 84 | RoW | EPO Feeding Program | King's College London | Feeding Practices | 03/24 | 03/24 | | |
NCT04367116: The Study to Evaluate the Safety and Efficacy of Spinal Cord Stimulation on Progressive Supranuclear Palsy |
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| Terminated | N/A | 3 | RoW | Spinal Cord Stimulation | Huashan Hospital | Progressive Supranuclear Palsy, Spinal Cord Stimulation | 12/23 | 12/23 | | |
| Completed | N/A | 210 | RoW | OrbusNeich Scoreflex TRIO, OrbusNeich Scoreflex NC | OrbusNeich, CCRC Medtech (Shanghai) Co., Ltd. | Coronary Arteriosclerosis | 04/24 | 05/24 | | |
NCT06300216: A Real-world Study of Octreotide Microspheres in Chinese Patients With Neuroendocrine Tumors |
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| Not yet recruiting | N/A | 500 | RoW | Octreotide microspheres | Qilu Hospital of Shandong University | Neuroendocrine Tumors | 11/27 | 05/28 | | |
NCT06319131: Nadroparin Versus TIPS in Cirrhotic Patients With Refractory Asymptomatic PVT |
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| Not yet recruiting | N/A | 84 | NA | TIPS, Nadroparin | Shanghai Zhongshan Hospital, Shanghai 6th People's Hospital, ShuGuang Hospital, Tongji Hospital, Renmin Hospital of Wuhan University | Portal Vein Thrombosis | 05/25 | 05/26 | | |
| Recruiting | N/A | 128 | RoW | Calorie-restricted diet (CRD), Time-restricted eating (TRE) | Xiaoyan Shi, Soochow University | Childhood Obesity | 12/25 | 12/26 | | |
SPEED, NCT05561699: Sequential Preoperative Penpulimab Combined With Chemoradiotherapy(CRT) for Locally Advanced Esophageal Squamous Cell Cancer |
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| Not yet recruiting | N/A | 66 | RoW | Penpulimab Combined With CRT | Shanghai Zhongshan Hospital | Esophageal Squamous Cell Carcinoma | 09/24 | 12/24 | | |
| Active, not recruiting | N/A | 51 | RoW | MitraClip procedure | Abbott Medical Devices | Mitral Regurgitation | 05/24 | 05/25 | | |
NCT05516680: Effects and Central Mechanism of Electroacupuncture and MRI-navigated rTMS for PSD |
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| Recruiting | N/A | 64 | RoW | electro-acupuncture, MRI-navigated rTMS | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Post-stroke Depression, Healthy | 06/25 | 08/25 | | |
| Recruiting | N/A | 1017 | US, RoW | Infuse™ Bone Graft (Infuse™), Intervertebral body fusion device and Medtronic posterior Fixation Systems | Medtronic Spinal and Biologics | Degenerative Disease of the Lumbosacral Spine | 04/26 | 04/28 | | |
| Active, not recruiting | N/A | 17875 | RoW | | Peking University People's Hospital, BeijingNewBiorayTechnologyCo.,Ltd., Hangzhou Newhorizon Health Technology Co., Ltd. | Human Papillomavirus Infection, Cervical Cancer, Negative For Intraepithelial Lesion Or Malignancy, Atypical Squamous Cells of Undetermined Significance, Atypical Squamous Cells, Cannot Rule Out High-grade Squamous Intraepithelial Lesion, Cervical Squamous Intraepithelial Lesion, Low-Grade Squamous Intraepithelial Lesions, High-Grade Squamous Intraepithelial Lesions, Cervical Intraepithelial Neoplasia Grade I, Cervical Intraepithelial Neoplasia Grade II, Cervical Intraepithelial Neoplasia, Grade III, Atypical Glandular Cells, Atypical Glandular Cells Not Otherwise Specified, Atypical Glandular Cells, Favor Neoplastic, Cervical Squamous Cell Carcinoma, Adenocarcinoma in Situ, Cervical Adenocarcinoma | 07/26 | 08/27 | | |
| Recruiting | N/A | 1332 | RoW | The lying flat (0°-10°) head position for 72 hours, The The head elevation (30°-40°) position for 72 hours | Zhengzhou Yuan | Stroke, Acute, Endovascular Therapy | 11/25 | 04/26 | | |
BEST-BAO, NCT05631847: Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke |
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| Recruiting | N/A | 336 | RoW | Endovascular treatment, Intravenous thrombolysis (Alteplase) | Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion, Thrombosis, Alteplase, Endovascular Treatment | 01/27 | 05/27 | | |
NCT04078230: Regional or Extend LymphAdenectomy During Resection of Intrahepatic Cholangiocarcinoma |
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| Recruiting | N/A | 168 | US, RoW | Extend LymphAdenectomy | Second Affiliated Hospital, School of Medicine, Zhejiang University | Intrahepatic Cholangiocarcinoma | 12/27 | 12/27 | | |
ForPDCN, NCT03649503: The National Registry Study for the Real-world Patients with Parkinsonian Disorders in China |
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| Recruiting | N/A | 100000 | RoW | No intervention | Huashan Hospital, First Affiliated Hospital, Sun Yat-Sen University, Tianjin Medical University General Hospital, Peking Union Medical College Hospital, Chinese PLA General Hospital, Shanghai Zhongshan Hospital, The First Affiliated Hospital of the Fourth Military Medical University, Affiliated Hospital of North Sichuan Medical College, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Changshu Hospital of Traditional Chinese Medicine, The Affiliated Hospital of Qingdao University, Guangxi Ruikang Hospital, Xi'an Central Hospital, First Affiliated Hospital of Chongqing Medical University, The First Hospital of Hebei Medical University, Jieyang People's Hospital, Luoyang Central Hospital, Taian City Central Hospital, Gansu Provincial Hospital, First Affiliated Hospital of Harbin Medical University, Daqing Oil Field Hospital, Fujian Provincial Hospital, The Affiliated Hospital of Xuzhou Medical University, Taizhou Hospital, Zhejiang Hospital, The 101st Hospital of Chinese People's Liberation Army, The First Affiliated Hospital of Zhengzhou University, The First Affiliated Hospital of Dalian Medical University, China-Japan Union Hospital, Jilin University, Wuhan No.1 Hospital, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Northern Jiangsu People's Hospital, Shanghai Tongji Hospital, Tongji University School of Medicine, Shanghai 5th People's Hospital, Third People's Hospital, Huzhou City, Zhejiang Province, China, Suzhou Municipal Hospital, Ningbo No. 1 Hospital, The First People's Hospital of Changzhou, Affiliated Hospital of Jiangsu University, The Second Affiliated Hospital of Harbin Medical University, The First Affiliated Hospital with Nanjing Medical University, Fujian Medical University Union Hospital, Shanghai Changzheng Hospital, Second Affiliated Hospital of Nanchang University, Jingjiang People's Hospital, Qingdao Municipal Hospital, Xi'an No.3 Hospital, Lianyungang Hospital Affiliated Bengbu Medical College, The First People's Hospital of Jingzhou, Shanghai 10th People's Hospital, Huadong Hospital, No. 102 Hospital of Chinese People's Liberation Army, Shandong Provincial Hospital, Anhui Provincial Hospital, Affiliated Hospital of Guangdong Medical University | Parkinsonian Disorders | 09/28 | 09/33 | | |
Wang, Ji Yao |
NCT03363763: Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex |
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| Terminated | 2 | 24 | US, RoW | Sirolimus 0.2%, Rapamune, rapamycin, mTOR inhibitor, Sirolimus 0.4%, Placebo ointment, Placebo | Aucta Pharmaceuticals, Inc | Angiofibroma of Face, Tuberous Sclerosis | 03/23 | 03/23 | | |
NCT05531669: Effect of PLAY Project Intervention Program on Children With ASD |
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| Recruiting | N/A | 200 | RoW | PLAY Project, Parental Education | Tongji Hospital, Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology, Fuzhou Children's Hospital of Fujian Medical University, Third Affiliated Hospital of Zhengzhou University, Shenzhen Hospital of Southern Medical University, Children's Hospital of Zhejiang University School of Medicine | Autism Spectrum Disorder | 12/23 | 12/23 | | |
Cai, Xiujun |
NCT05862337: Anlotinib Hydrochloride Capsules Combined With Penpulimab Injection for the Treatment of Hepatocellular Carcinoma at High Risk of Recurrence. |
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| Recruiting | 3 | 480 | RoW | Anlotinib hydrochloride capsules, Penpulimab injection, Anlotinib hydrochloride capsules -matching placebo, Penpulimab injection -matching placebo | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Hepatocellular Carcinoma | 08/24 | 12/26 | | |
PANOVA-3, NCT03377491: Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel |
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| Completed | 3 | 571 | Europe, Canada, US, RoW | NovoTTF-200T, TTFields, Gemcitabine, nab paclitaxel | NovoCure Ltd. | Pancreas Adenocarcinoma | 10/24 | 10/24 | | |
PRECAM-R, NCT05752136: Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma |
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| Recruiting | 3 | 108 | RoW | Envafolimab | Sir Run Run Shaw Hospital | Rectal Cancer | 04/25 | 12/28 | | |
PRECAM, NCT05216653: Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma |
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| Active, not recruiting | 2 | 32 | RoW | Envafolimab, KN053, Oxaliplatin, Capecitabine, Short-course Radiation, TME surgery, total mesorectal excision | Sir Run Run Shaw Hospital | MSS Locally Advanced Rectal Adenocarcinoma | 03/23 | 03/25 | | |
NCT06266832: The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma |
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| Recruiting | 2 | 30 | RoW | Adebrelimab, SHR-1316, Oxaliplatin, Capecitabine, Short-course Radiation, Biopsy | Sir Run Run Shaw Hospital | Rectal Adenocarcinoma | 01/25 | 12/27 | | |
RECMULRA-TNT, NCT05858567: Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma |
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| Recruiting | 2 | 30 | RoW | Envafolimab | Sir Run Run Shaw Hospital | Rectal Cancer | 12/24 | 06/25 | | |
NCT05035108: The Treatment of Bioartificial Liver With hiHep Cells After Extensive Hepatectomy |
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| Recruiting | 1 | 10 | RoW | hiHep bioartificial liver therapy | Sir Run Run Shaw Hospital, Hexaell Biotech Co., Ltd | Hepatoma Resectable | 11/21 | 12/21 | | |
NCT06560827: CT011 Autologous CAR-T Cells in Patients With Hepatocellular Carcinoma at Risk of Recurrence After Surgical Resection |
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| Recruiting | 1 | 30 | RoW | CT011 CAR-GPC3 T Cells Injection | CARsgen Therapeutics Co., Ltd., Shanghai Zhongshan Hospital | HCC | 12/26 | 06/27 | | |
NCT06019702: Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen Alone in Subjects With Advanced Digestive System Neoplasms |
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| Recruiting | 1 | 20 | RoW | iNeo-Vac-R01 | Sir Run Run Shaw Hospital, Hangzhou Neoantigen Therapeutics Co., Ltd. | Digestive System Neoplasms | 08/27 | 12/27 | | |
NCT06026800: Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Combination With Standard First-line Treatment in Subjects With Advanced Digestive System Neoplasms |
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| Recruiting | 1 | 20 | RoW | iNeo-Vac-R01 | Sir Run Run Shaw Hospital, Hangzhou Neoantigen Therapeutics Co., Ltd. | Digestive System Neoplasms | 08/27 | 12/27 | | |
NCT06026774: Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Subjects With Resected Digestive System Neoplasms |
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| Recruiting | 1 | 20 | RoW | iNeo-Vac-R01 in combination with standard adjuvant therapy | Sir Run Run Shaw Hospital, Hangzhou Neoantigen Therapeutics Co., Ltd. | Digestive System Neoplasms | 08/27 | 12/27 | | |
NCT06587152: Clinical Trial to Evaluate the Efficacy and Safety of a Thoracic and Abdominal Endoscopic Surgical System |
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| Enrolling by invitation | N/A | 60 | RoW | Robot-assisted surgery | Cornerstone Robotics | Pathologic Stage I Gastric Cancer AJCC v8, Colorectal Cancer, Esophageal Cancer, Hepatectomy, Radical Hysterectomy | 09/24 | 02/25 | | |
NCT06204497: The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients |
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| Recruiting | N/A | 570 | RoW | Stent-based Diverting Technique | Sir Run Run Shaw Hospital | Rectal Neoplasms | 12/24 | 06/25 | | |
SEPEN-CD, NCT06587178: Semi-elemental Versus Polymeric EEN in the Preoperative Optimization for Patients with CD |
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| Not yet recruiting | N/A | 304 | RoW | peptison liquid, Nutricia, Amsterdam, Netherlands, Enteral nutritional suspension | Wei Zhou | Crohn Disease, Nutrition Disorders, Surgery | 12/25 | 12/25 | | |
Qin, Lunxiu |
NAUTICALCRC, NCT05004350: A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer. |
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| Active, not recruiting | 2 | 103 | RoW | Encorafenib, Braftovi®, PF-07263896, W0090, LGX818, ONO-7702, Cetuximab, Erbitux®, C225, FOLFIRI, Folinic acid + Fluorouracil + Irinotecan | Pierre Fabre Medicament, Merck KGaA, Darmstadt, Germany | BRAF V600E, Metastatic Colorectal Cancer | 12/23 | 01/25 | | |
NCT04974281: PD-1 Antibody and Lenvatinib Plus TACE on Downstaging BCLC B/C HCC |
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| Recruiting | 1 | 50 | RoW | PD-1 and Lenvatinib Plus TACE | Fudan University | Hepatocellular Carcinoma | 12/22 | 12/22 | | |
NCT03838796: Lenvatinib Combined With TACE to Prevent the Recurrence in High-risk Patients With Hepatocellular Carcinoma |
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| Active, not recruiting | N/A | 297 | RoW | lenvatinib, lenvatinib treatment, TACE, transcatheter arterial chemoembolization | Fudan University | Hepatocellular Carcinoma | 06/22 | 06/23 | | |
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NCT02526043: Laparoscopic Versus Open Liver Resection for Hepatocellular Carcinoma |
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| Active, not recruiting | N/A | 180 | RoW | laparoscopic hepatectomy, Open hepatectomy | Fudan University | Hepatocellular Carcinoma | 12/22 | 12/22 | | |