| Craft, Suzanne |
| Active, not recruiting | 2/3 | 326 | US | Placebo oral tablet, Placebo, extended release metformin, Metformin | Columbia University, Johns Hopkins University, National Institute on Aging (NIA), University of Rochester, University of Iowa, Boston University, Wake Forest University, Rush University, Pennington Biomedical Research Center, University of Miami, Emory University, Georgetown University, NYU Langone Health, University of California, Berkeley, The University of Texas Health Science Center at San Antonio, University of Washington, State University of New York - Upstate Medical University, University of Texas Southwestern Medical Center, University at Buffalo, University of Cincinnati, Eastern Virginia Medical School, Medical College of Wisconsin, University of Kansas Medical Center, University of New Mexico, Stanford University, University of California, Irvine, Cornell University | Mild Cognitive Impairment | 04/26 | 04/27 | | |
NCT03857321: Study of Nasal Insulin to Fight Forgetfulness - Device Study |
|
|
| Active, not recruiting | 2 | 30 | US | Insulin, Humulin® R U-100, Placebo, placebo to Humulin® R U-100, Sterile saline, intranasal nebulizer-like device | Wake Forest University Health Sciences | Mild Cognitive Impairment, Cognitive Impairment | 08/25 | 08/25 | | |
| Suspended | 2 | 30 | US | 20 IU Humulin® R U-100 (NDC: 0002-8215, Eli Lilly & Company), Humulin® R U-100, 40 IU Humulin® R U-100 (NDC: 0002-8215, Eli Lilly & Company) | Wake Forest University Health Sciences | Mild Cognitive Impairment, Cognitive Impairment | 10/26 | 10/27 | | |
| Completed | 2 | 30 | US | Insulin (Humulin® R U-100), Empagliflozin 10 MG, Aptar Pharma CPS Intranasal Delivery Device, Placebo (Insulin Diluent), Placebo (Capsules) | Wake Forest University Health Sciences | Mild Cognitive Impairment, Cognitive Impairment, Alzheimer Disease | 09/24 | 09/24 | | |
| Active, not recruiting | 2 | 48 | Europe, US | Dasatinib + Quercetin, Placebo Capsules | Wake Forest University Health Sciences, The University of Texas Health Science Center at San Antonio | Alzheimer Disease, Early Onset, Mild Cognitive Impairment | 01/28 | 01/29 | | |
START, NCT05531656: A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease |
|
|
| Recruiting | 2 | 540 | US | CT1812, Study Drug Active, Placebo, Matching Placebo | Cognition Therapeutics, National Institute on Aging (NIA), Alzheimer's Clinical Trials Consortium | Early Alzheimer's Disease | 04/27 | 04/27 | | |
| Not yet recruiting | 2 | 40 | NA | Insulin (Humulin® R U-100), Placebo, Insulin Diluent, Aptar Pharma CPS Intranasal Delivery Device | Wake Forest University Health Sciences | Mild Cognitive Impairment, Cognitive Impairment, Alzheimer Disease, Early Onset | 05/29 | 05/31 | | |
AcAc PET, NCT03130036: Biodistribution of [11C]Acetoacetate/[18F]Fluorodeoxyglucose in Subjects With Risk Factors for Alzheimer's Disease |
|
|
| Completed | N/A | 42 | US | [11C]Acetoacetate[18F]Fluorodeoxyglucose positron emission tomography scan | Wake Forest University Health Sciences | Mild Cognitive Impairment | 06/24 | 06/24 | | |
| Completed | N/A | 220 | US | | University of Southern California, National Institute on Aging (NIA), Alzheimer's Therapeutic Research Institute, Alzheimer's Clinical Trials Consortium, Brigham and Women's Hospital, Cleveland Clinic Lou Ruvo Center for Brain Health | Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer Disease, Dementia | 04/24 | 04/24 | | |
NCT03089827: Biodistribution of [11C]PIB in Patients With Risk Factors for Alzheimer's Disease |
|
|
| Enrolling by invitation | N/A | 800 | US | | Wake Forest University Health Sciences | Alzheimer Disease, Mild Cognitive Impairment | 04/30 | 04/31 | | |
| Recruiting | N/A | 120 | US | low carbohydrate/high fat diet, low fat/high carbohydrate diet | Wake Forest University Health Sciences, National Institute on Aging (NIA) | Alzheimer Disease, Mild Cognitive Impairment | 04/25 | 04/26 | | |
| Dahl, Deborah |
| Completed | 2 | 30 | US | Insulin (Humulin® R U-100), Empagliflozin 10 MG, Aptar Pharma CPS Intranasal Delivery Device, Placebo (Insulin Diluent), Placebo (Capsules) | Wake Forest University Health Sciences | Mild Cognitive Impairment, Cognitive Impairment, Alzheimer Disease | 09/24 | 09/24 | | |
