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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Rapacciuolo, Antonio
ARMYDA-AMULET, NCT05554822: Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study	Recruiting	3	574	Europe	Aspirin 100mg, Aspirin 100 mg OD plus clopidogrel 75 mg OD	Azienda Ospedaliero Universitaria Maggiore della Carita, Abbott Medical Devices	Left Atrial Appendage Occlusion, Antiplatelet Therapy	12/23	12/23
CRT-NEXT, NCT03587064: Comparison of CRT-D and CRT-DX Systems	Recruiting	N/A	640	Europe	Conventional 3-lead CRT defibrillator system implantation, 2-lead CRT defibrillator system implantation	Associazione Portatori Dispositivi Impiantabili Cardiaci	Heart Failure, Cardiac Resynchronization Therapy	04/25	04/25
TRICE-HF, NCT05103267: Tauropace to Prevent Cardiac Implantable Device Infections in Heart Failure Patients	Recruiting	N/A	500	Europe	Tauropace	Federico II University	Infection Cardiac, Heart Failure, Cardiac Implantable Electronic Device Infections, High Risk	06/23	06/24
Multitude, NCT06311149: Multicenter Evaluation of Patients Using LATITUDE Monitoring System	Recruiting	N/A	20000	Europe		University Hospital of Ferrara	Cardiovascular Diseases, Arrhythmias, Cardiac, Heart Failure, Sudden Cardiac Death	12/43	12/43
ASTRAL-4LV, NCT04463641: Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy	Active, not recruiting	N/A	92	Europe	Implantation of the Axone 4LV Lead	MicroPort CRM	Heart Failure, Cardiac Resynchronization Therapy	06/24	12/27
OSIRIS, NCT04118803: Observational Study on Inappropriate Therapies	Active, not recruiting	N/A	881	Europe, US	ICD replacement or upgrade	MicroPort CRM	Inappropriate Shocks From Implanted Defibrillator, ICD Replacement or Upgrade	05/25	05/25
REACTION, NCT05175937: REal World Assessment for Patients Implanted With Implantable CardioverTer DefibrIllatOr Using Bluetooth Technology	Recruiting	N/A	1104	Europe	smartphone APP based remote monitoring, bedside transmitter based remote monitoring	Federico II University	Cardiac Arrhythmias, Sudden Cardiac Death, Heart Failure	12/23	04/25

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Rapacciuolo, Antonio
ARMYDA-AMULET, NCT05554822: Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study	Recruiting	3	574	Europe	Aspirin 100mg, Aspirin 100 mg OD plus clopidogrel 75 mg OD	Azienda Ospedaliero Universitaria Maggiore della Carita, Abbott Medical Devices	Left Atrial Appendage Occlusion, Antiplatelet Therapy	12/23	12/23
CRT-NEXT, NCT03587064: Comparison of CRT-D and CRT-DX Systems	Recruiting	N/A	640	Europe	Conventional 3-lead CRT defibrillator system implantation, 2-lead CRT defibrillator system implantation	Associazione Portatori Dispositivi Impiantabili Cardiaci	Heart Failure, Cardiac Resynchronization Therapy	04/25	04/25
TRICE-HF, NCT05103267: Tauropace to Prevent Cardiac Implantable Device Infections in Heart Failure Patients	Recruiting	N/A	500	Europe	Tauropace	Federico II University	Infection Cardiac, Heart Failure, Cardiac Implantable Electronic Device Infections, High Risk	06/23	06/24
Multitude, NCT06311149: Multicenter Evaluation of Patients Using LATITUDE Monitoring System	Recruiting	N/A	20000	Europe		University Hospital of Ferrara	Cardiovascular Diseases, Arrhythmias, Cardiac, Heart Failure, Sudden Cardiac Death	12/43	12/43
ASTRAL-4LV, NCT04463641: Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy	Active, not recruiting	N/A	92	Europe	Implantation of the Axone 4LV Lead	MicroPort CRM	Heart Failure, Cardiac Resynchronization Therapy	06/24	12/27
OSIRIS, NCT04118803: Observational Study on Inappropriate Therapies	Active, not recruiting	N/A	881	Europe, US	ICD replacement or upgrade	MicroPort CRM	Inappropriate Shocks From Implanted Defibrillator, ICD Replacement or Upgrade	05/25	05/25
REACTION, NCT05175937: REal World Assessment for Patients Implanted With Implantable CardioverTer DefibrIllatOr Using Bluetooth Technology	Recruiting	N/A	1104	Europe	smartphone APP based remote monitoring, bedside transmitter based remote monitoring	Federico II University	Cardiac Arrhythmias, Sudden Cardiac Death, Heart Failure	12/23	04/25