| Boudreaux, Edwin D |
| Recruiting | N/A | 670 | US | Jaspr App + JAH, ETAU, Enhanced Treatment As Usual | University of Massachusetts, Worcester, Ohio State University, Evidence-Based Practice Institute, Seattle, WA, Worcester Polytechnic Institute, National Institute of Mental Health (NIMH), University of Colorado, Denver | Suicidal Ideation, Suicide Attempt, Self Harm | 04/27 | 04/27 | | |
| Recruiting | N/A | 44000 | US | Telehealth in preventing suicide (TIPS), Modified ED-SAFE, Treatment as Usual (TAU) | University of Massachusetts, Worcester, Community HealthLink, Collective Medical, National Institute of Mental Health (NIMH) | Suicide Risk | 09/25 | 09/25 | | |
| Recruiting | N/A | 102 | US | OARSCM Software Application, Opioid Addiction Recovery Support - Contingency Management (OARSCM), MyMAT Software Application, MyMAT | Q2i, LLC, University of Massachusetts, Worcester, National Institute on Drug Abuse (NIDA) | Opioid Use Disorder | 05/25 | 05/25 | | |
| Completed | N/A | 493756 | US | Suicide Risk Screening, Safety Planning, Care transition facilitation, A Lean Implementation Strategy | University of Massachusetts, Worcester, National Institute of Mental Health (NIMH) | Suicide | 12/23 | 12/23 | | |
| Enrolling by invitation | N/A | 27908 | US | Jaspr App | University of Massachusetts, Worcester, Ohio State University, Evidence-Based Practice Institute, Seattle, WA, National Institute of Mental Health (NIMH), Worcester Polytechnic Institute, University of Colorado, Denver | Suicidal Ideation, Suicide Attempt, Self Harm | 06/27 | 06/27 | | |
| Hanel, Ricardo A |
NECC, NCT04852783: US IDE Study of the Contour NEurovasCular System™ for IntraCranial Aneurysm Repair |
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| Active, not recruiting | 4 | 250 | US | Contour Neurovascular System | Cerus Endovascular, Inc. | Aneurysm, Intracranial | 12/25 | 12/29 | | |
CAPTIVA, NCT05047172: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis |
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| Recruiting | 3 | 1683 | US | Ticagrelor + Aspirin, Brilinta, Rivaroxaban + Aspirin, Xarelto, Clopidogrel + Aspirin, Plavix, Risk Factor Management | University of Florida, National Institute of Neurological Disorders and Stroke (NINDS), University of Cincinnati, Medical University of South Carolina, Janssen Scientific Affairs, LLC, AstraZeneca | Intracranial Arteriosclerosis, Stroke | 05/28 | 05/28 | | |
| Recruiting | 2/3 | 200 | Europe, Canada, US | Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device, EmboTrap III, Initial medical management (iMM) | Emory University, University of Calgary, University of Cincinnati, Heidelberg University, Children's Hospital Medical Center, Cincinnati | Cerebral Ischemia | 12/24 | 12/24 | | |
| Recruiting | 1 | 24 | US | PP-007 (Two doses administered 24±6 hours apart) + SOC (IVT or MT or IVT+MT), Sanguinate | Prolong Pharmaceuticals | Acute Ischemic Stroke | 12/24 | 02/25 | | |
NCT04518670: Success in Comaneci-assist Coils Embolization Surveillance Study (SUCCESS) |
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| Completed | N/A | 90 | US | Comaneci Embolization Assist Device | Rapid Medical | Intracranial Aneurysm | 05/24 | 07/24 | | |
| Completed | N/A | 121 | Canada, US, RoW | AneurysmFlow | Philips Clinical & Medical Affairs Global | Intracranial Aneurysm | 11/23 | 11/23 | | |
STEM, NCT04410146: The SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma |
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| Completed | N/A | 310 | Europe, US | SQUID Embolization, SQUID Embolization and Surgical Evacuation, Surgical Evacuation, Other: Medical Management | Balt USA, Balt Extrusion, Embo-Flüssigkeiten A.G., AXIOM Real Time Metrics | Subdural Hematoma, Chronic | 02/24 | 05/24 | | |
NCT05018650: A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX) |
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| Active, not recruiting | N/A | 250 | US, RoW | Route 92 Medical Reperfusion System | Route 92 Medical, Inc. | Acute Ischemic Stroke | 06/24 | 06/24 | | |
NCT05232838: US Pilot Study of the CereVasc® EShunt® System in Normal Pressure Hydrocephalus |
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| Recruiting | N/A | 50 | US | eShunt Implant | CereVasc Inc, AlvaMed, Inc., Simplified Clinical Data Systems, LLC | Hydrocephalus, Normal Pressure, Hydrocephalus | 01/25 | 01/30 | | |
VANTAGE, NCT04391803: EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms with the Pipeline™ Flex Embolization Device with Shield TEchnology™ (ELEVATE) |
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| Recruiting | N/A | 200 | NA | Pipeline™ Flex Embolization Device with Shield Technology™, Pipeline™ Shield Device | Medtronic Neurovascular Clinical Affairs | Intracranial Aneurysm, Ruptured Aneurysm | 01/26 | 01/27 | | |
EMBOLISE, NCT04402632: Embolization of the Middle Meningeal Artery with ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma |
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| Active, not recruiting | N/A | 600 | US | Surgical Management, Surgical Management + Treatment, No Treatment, Treatment | Medtronic Neurovascular Clinical Affairs | Subdural Hematoma | 12/24 | 03/25 | | |
| Recruiting | N/A | 2000 | Europe, US, RoW | EmboTrap® Revascularization Device, CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter, CEREGLIDE 71 Intermediate Catheter | Cerenovus, Part of DePuy Synthes Products, Inc. | Cerebral Stroke | 03/25 | 06/25 | | |
| Recruiting | N/A | 520 | US | Conventional Surgery, Middle Meningeal Artery Embolization (MMAE) | The University of Texas Medical Branch, Galveston, National Institute of Neurological Disorders and Stroke (NINDS) | Chronic Subdural Hematoma | 09/28 | 09/28 | | |
NCT04701684: WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment) |
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| Recruiting | N/A | 564 | Europe, US, RoW | Direct to Angio Suite (DTAS) Philips' CBCT triage, Conventional CT/MR triage | Philips Clinical & Medical Affairs Global | Stroke, Acute | 12/25 | 12/25 | | |
| Active, not recruiting | N/A | 246 | US | Treatment of Intracranial Aneurysms | Medtronic Neurovascular Clinical Affairs | Intracranial Aneurysm | 03/26 | 04/28 | | |
| Recruiting | N/A | 225 | Europe, US | Millipede System | Perfuze | Acute Ischemic Stroke | 07/25 | 10/25 | | |
CLASS, NCT05636124: Kaneka IED Coil System for the Treatment of Wide Necked Ruptured and Unruptured Intracranial Aneurysms |
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| Recruiting | N/A | 50 | US | Kaneka i-ED coil | Icahn School of Medicine at Mount Sinai, Kaneka Corporation | Intracranial Aneurysms, Wide Neck Intracranial Aneurysms | 07/25 | 07/25 | | |
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial |
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| Active, not recruiting | N/A | 2486 | Europe, Canada, US, RoW | Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS | Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS) | Carotid Stenosis | 02/26 | 02/26 | | |
| Recruiting | N/A | 150 | US | Citadel Embolization Device | Stryker Neurovascular | Unruptured Wide-neck Aneurysms | 06/26 | 06/26 | | |
CAPTIVA-MRI, NCT05907629: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging |
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| Recruiting | N/A | 300 | US | MRI | Yale University, National Institute of Neurological Disorders and Stroke (NINDS) | Stroke, Intracranial Atherosclerotic Stenosis (ICAS) | 03/29 | 03/29 | | |
| Recruiting | N/A | 2000 | Europe, US, RoW | EmboTrap® Revascularization Device, CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter | Cerenovus, Part of DePuy Synthes Products, Inc. | Cerebral Stroke | 07/24 | 10/24 | | |
| Bodkin, Noelle |
PICASSO, NCT05611242: Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial |
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| Recruiting | 3 | 404 | US | MT+CAS with IV-AP, Thrombectomy, MT+CAS with PO-AP, MT+CAT with PO-AP | Mercy Health Ohio | Acute Ischemic Stroke | 03/26 | 05/27 | | |
| Recruiting | 2/3 | 200 | Europe, Canada, US | Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device, EmboTrap III, Initial medical management (iMM) | Emory University, University of Calgary, University of Cincinnati, Heidelberg University, Children's Hospital Medical Center, Cincinnati | Cerebral Ischemia | 12/24 | 12/24 | | |
NCT05018650: A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX) |
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| Active, not recruiting | N/A | 250 | US, RoW | Route 92 Medical Reperfusion System | Route 92 Medical, Inc. | Acute Ischemic Stroke | 06/24 | 06/24 | | |
WEB PAS, NCT04839705: Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device |
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| Recruiting | N/A | 180 | US | WEB | Microvention-Terumo, Inc. | Wide Neck Bifurcation Intracranial Aneurysms | 12/25 | 12/29 | | |
CREST-2, NCT02089217: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial |
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| Active, not recruiting | N/A | 2486 | Europe, Canada, US, RoW | Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA, Intensive Medical Management - no CAS | Thomas G. Brott, M.D., National Institute of Neurological Disorders and Stroke (NINDS) | Carotid Stenosis | 02/26 | 02/26 | | |
| Recruiting | N/A | 150 | US | Citadel Embolization Device | Stryker Neurovascular | Unruptured Wide-neck Aneurysms | 06/26 | 06/26 | | |
| Bankier, Alexander |
DEEP-Lung-IV, NCT04994795: Predictive Multimodal Signatures Associated With Response to Treatment and Prognosis of Patients With Stage IV Non-small Cell Lung Cancer |
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| Active, not recruiting | N/A | 4000 | Europe, Canada, US, RoW | Predictive models (data collection) | Sophia Genetics SAS | Non-small Cell Lung Cancer Metastatic | 12/24 | 02/25 | | |
| Singh, Jasmeet |
PICASSO, NCT05611242: Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial |
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| Recruiting | 3 | 404 | US | MT+CAS with IV-AP, Thrombectomy, MT+CAS with PO-AP, MT+CAT with PO-AP | Mercy Health Ohio | Acute Ischemic Stroke | 03/26 | 05/27 | | |
WEB PAS, NCT04839705: Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device |
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| Recruiting | N/A | 180 | US | WEB | Microvention-Terumo, Inc. | Wide Neck Bifurcation Intracranial Aneurysms | 12/25 | 12/29 | | |
| Recruiting | N/A | 150 | US | Citadel Embolization Device | Stryker Neurovascular | Unruptured Wide-neck Aneurysms | 06/26 | 06/26 | | |
NCT05409989: MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study |
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| Recruiting | N/A | 154 | US | FRED™ X™, Flow Re-Direction Endoluminal Device X | Microvention-Terumo, Inc. | Intracranial Aneurysm | 09/29 | 11/29 | | |
| Paulsen, Richard |
WEB PAS, NCT04839705: Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device |
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| Recruiting | N/A | 180 | US | WEB | Microvention-Terumo, Inc. | Wide Neck Bifurcation Intracranial Aneurysms | 12/25 | 12/29 | | |
NCT05409989: MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study |
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| Recruiting | N/A | 154 | US | FRED™ X™, Flow Re-Direction Endoluminal Device X | Microvention-Terumo, Inc. | Intracranial Aneurysm | 09/29 | 11/29 | | |
| Abdelsalem, Ahmed |
| Recruiting | N/A | 150 | US | Citadel Embolization Device | Stryker Neurovascular | Unruptured Wide-neck Aneurysms | 06/26 | 06/26 | | |
| Dornbos, David |
NCT06119061: Telavancin Blood and Cerebrospinal Fluid Concentrations in Patients With Subarachnoid Hemorrhage |
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| Recruiting | 4 | 20 | US | Telavancin Injection, Vibativ | Aaron Cook, Cumberland Pharmaceuticals | Subarachnoid Hemorrhage, Aneurysmal | 12/25 | 01/26 | | |
WEB PAS, NCT04839705: Post Approval Study - Evaluate the Long-Term Safety and Effectiveness of the WEB Device |
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| Recruiting | N/A | 180 | US | WEB | Microvention-Terumo, Inc. | Wide Neck Bifurcation Intracranial Aneurysms | 12/25 | 12/29 | | |
