| Hussain, Arif |
| Recruiting | 3 | 738 | Europe, US, RoW | Docetaxel 75 mg/m2, Docetaxel 60 mg/m2, Radium-223 | Memorial Sloan Kettering Cancer Center, Bayer | Prostate Cancer | 06/26 | 06/26 | | |
NCT04691804 / 2020-006063-28: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer |
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| Active, not recruiting | 3 | 496 | Europe, US, RoW | Fuzuloparib , Abiraterone acetate and Prednisone, SHR3162, Fuzuloparib Placebo， Abiraterone acetate and Prednisone | Jiangsu HengRui Medicine Co., Ltd. | Metastatic Castration-Resistant Prostate Cancer (mCRPC) | 12/26 | 12/26 | | |
PSMA-DC, NCT05939414: An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC. |
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| Recruiting | 3 | 450 | Europe, Canada, Japan, US, RoW | AAA617, (177Lu) vipivotide tetraxetan | Novartis Pharmaceuticals | Oligometastatic Prostate Cancer (OMPC) | 12/27 | 07/30 | | |
LUCIDA, NCT05458544: [Lu-177]Ludotadipep in Castration-resistant Prostate Cancer(CRPC): Investigation of Drug and Application |
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| Recruiting | 1/2 | 26 | US | [177Lu]Ludotadipep 3.7 GBq | FutureChem | Metastatic Castration-resistant Prostate Cancer | 06/25 | 06/25 | | |
| Recruiting | 1/2 | 144 | US | ONC-392, A humanized anti-CTLA4 IgG1 monoclonal antibody, Gotistobart, lutetium Lu 177 vipivotide tetraxetan, IV infusion, Q6W for up to 6 doses., Pluvicto | OncoC4, Inc., Prostate Cancer Clinical Trials Consortium | Metastatic Castration-resistant Prostate Cancer | 06/26 | 06/27 | | |
| Khalil, Maha |
LuTK02, NCT04495153: CAN-2409 Plus Prodrug With Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC |
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| Active, not recruiting | 2 | 90 | US | Aglatimagene besadenovec, CAN-2409, AdV-tk | Candel Therapeutics, Inc., NYU Langone Health | Non Small Cell Lung Cancer | 12/24 | 12/26 | | |
| Scilla, Katherine |
NCT04699838: Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer |
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| Recruiting | 2 | 30 | US | Cisplatin, Carboplatin, Etoposide, Durvalumab, Ceralasertib | Muhammad Furqan, AstraZeneca | Extensive Stage Small Cell Lung Cancer | 09/25 | 09/25 | | |
NCT04499053: Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer |
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| Recruiting | 2 | 18 | US | Durvalumab, Tremelimumab | Georgetown University, AstraZeneca | Carcinoma, Non-Small Cell Lung | 02/27 | 12/27 | | |
NCT03918252: Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma |
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| Active, not recruiting | 2 | 30 | US | Nivolumab Injection, Optivo, Ipilimumab Injection, Yervoy | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bristol-Myers Squibb | Mesothelioma | 06/25 | 06/26 | | |
| Recruiting | 1/2 | 500 | Europe, Canada, Japan, US, RoW | Oral repotrectinib (TPX-0005), repotrectinib | Turning Point Therapeutics, Inc., Zai Lab (Shanghai) Co., Ltd. | Locally Advanced Solid Tumors, Metastatic Solid Tumors | 02/28 | 02/28 | | |
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NCT05374538: VIC-1911 Monotherapy in Combination With Sotorasib for the Treatment of KRAS G12C-Mutant Non-Small Cell Lung Cancer |
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| Terminated | 1a/1b | 4 | US | VIC-1911, sotorasib, LUMAKRAS | Vitrac Therapeutics, LLC, Westat | Non-small Cell Lung Cancer | 08/23 | 08/23 | | |
LIQUIK, NCT04703153: LIQUId Biopsy for Detection of Actionable Genomic BiomarKers in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) |
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| Active, not recruiting | N/A | 151 | US | | Lucence Health Inc. | Non Small Cell Lung Cancer | 12/22 | 12/24 | | |
| Langlois, Robia-Janee |
NCT05374538: VIC-1911 Monotherapy in Combination With Sotorasib for the Treatment of KRAS G12C-Mutant Non-Small Cell Lung Cancer |
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| Terminated | 1a/1b | 4 | US | VIC-1911, sotorasib, LUMAKRAS | Vitrac Therapeutics, LLC, Westat | Non-small Cell Lung Cancer | 08/23 | 08/23 | | |
