| Torres, Carlos |
NCT05532787: Comparison of Accelerated Diagnostic Pathways for Acute Chest Pain in Emergency Departments in the United Arab Emirates |
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| Recruiting | N/A | 1200 | RoW | Application of acute chest pain risk stratification scores (HEART and EDACS) | Zayed Military Hospital | Acute Coronary Syndrome, Chest Pain | 02/23 | 03/23 | | |
NCT05325294: Evaluation of the Advanced Hybrid Closed Loop (AHCL) System in Type 1 Adults and Pediatrics Utilizing Lyumjev® |
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| Completed | N/A | 244 | US | MiniMed 780G System | Medtronic Diabetes, Eli Lilly and Company | Type 1 Diabetes | 01/24 | 01/24 | | |
NCT05224258: Evaluation of the MiniMed™ 780G System in Type 1 Adult and Pediatric Subjects Utilizing Insulin Fiasp® |
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| Completed | N/A | 240 | Canada, US, RoW | MiniMed 780G System | Medtronic Diabetes | Type 1 Diabetes | 06/24 | 06/24 | | |
| Iancu, Daniela |
ACT-TBI, NCT04318665: Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients ( Study) |
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| Completed | N/A | 200 | Canada | CT Perfusion | University of Manitoba, Canadian Institutes of Health Research (CIHR) | Traumatic Brain Injury | 08/23 | 08/23 | | |
| Completed | N/A | 205 | Europe, Canada | endovascular coiling with any type of currently approved coil (first or second generation), endovascular stenting with or without coiling. The stent may be any of the currently approved stents for intracranial aneurysms. | Centre hospitalier de l'Université de Montréal (CHUM), University Hospital, Brest | Intracranial Aneurysm | 01/23 | 04/23 | | |
iWEB, NCT03936647: The RISE Trial: A Randomized Trial on Intra-Saccular Endobridge Devices |
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| Recruiting | N/A | 250 | Canada | surgical clipping, simple coiling, high-porosity stenting with/ without coiling, intra-arterial flow diversion with/ without coiling, WEB embolization device | Centre hospitalier de l'Université de Montréal (CHUM) | Intracranial Aneurysm, Brain Aneurysm, Unruptured Cerebral Aneurysm, Ruptured Cerebral Aneurysm, Cerebral Aneurysm | 01/25 | 01/26 | | |
2BE3, NCT06034847: Treatment of Persistent Distal Occlusion After Successful Proximal Recanalization in Thrombectomy |
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| Not yet recruiting | N/A | 300 | Canada | Mechanical thrombectomy in proximal large vessels, Rescue mechanical thrombectomy in distal vessels | Centre hospitalier de l'Université de Montréal (CHUM) | Stroke, Acute Thrombotic | 01/28 | 01/29 | | |
| Papp, Steven |
NCT02999022: Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT) |
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| Recruiting | 2 | 160 | Canada | Lithium Carbonate, Lithium, Lactose Placebo, placebo | Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR) | Fractures | 12/24 | 06/25 | | |
| Not yet recruiting | N/A | 120 | Canada | Indwelling Catheter, Intermittent Catheterization | Ottawa Hospital Research Institute, The Ottawa Hospital | Urogenital, Urinary Tract Infections, Hip Fractures, Catheter Complications | 05/23 | 07/23 | | |
COPE, NCT04274530: Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial |
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| Recruiting | N/A | 1000 | Canada, US | Cognitive Behavioural Therapy, CBT | McMaster University, Orthopaedic Trauma Association, Canadian Institutes of Health Research (CIHR) | Pain, Postoperative, Pain, Acute, Pain, Chronic, Fractures, Closed, Fractures, Open | 08/25 | 08/25 | | |
| Dowlatshahi, Dar |
| Active, not recruiting | 4 | 948 | Europe, Canada, US, RoW | Edoxaban, Lixiana, Savaysa, Non-anticoagulant medical therapy | Population Health Research Institute | Intracranial Hemorrhages, Atrial Fibrillation | 04/26 | 10/26 | | |
| Recruiting | 3 | 860 | Europe, Canada, Japan, US | Recombinant Activated Factor VII (rFVIIa), NovoSeven, NiaStase, Placebo | Joseph Broderick, MD, Novo Nordisk A/S, National Institute of Neurological Disorders and Stroke (NINDS) | Intracerebral Hemorrhage | 01/28 | 01/28 | | |
| Recruiting | 2/3 | 200 | Europe, Canada, US | Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device, EmboTrap III, Initial medical management (iMM) | Emory University, University of Calgary, University of Cincinnati, Heidelberg University, Children's Hospital Medical Center, Cincinnati | Cerebral Ischemia | 12/24 | 12/24 | | |
| Terminated | 2 | 142 | Canada | labetalol/hydralazine/enalapril | University of Alberta | Intracerebral Hemorrhage | 11/21 | 12/21 | | |
| Recruiting | N/A | 45 | Canada | FDG PET/CT, Usual Care | Ottawa Hospital Research Institute, Brain Canada, Heart and Stroke Foundation of Canada, Canadian Stroke Consortium (CSC) | Occult Cancer | 01/25 | 01/26 | | |
| Active, not recruiting | N/A | 530 | Europe, Canada, US | endovascular thrombectomy (EVT), solitaire X, Standarad medical care | Dr. Michael D Hill, University of Calgary | Acute Ischemic Stroke | 12/25 | 06/26 | | |
| Schwarz, Betty Anne |
| Completed | N/A | 323 | Canada | flow diversion, conservative management, endovascular coiling, balloon parent vessel occlusion, surgical clipping | Centre hospitalier de l'Université de Montréal (CHUM), Centre de Recherche du Centre Hospitalier de l'Université de Montréal | Intracranial Aneurysm | 01/23 | 01/23 | | |
| Completed | N/A | 205 | Europe, Canada | endovascular coiling with any type of currently approved coil (first or second generation), endovascular stenting with or without coiling. The stent may be any of the currently approved stents for intracranial aneurysms. | Centre hospitalier de l'Université de Montréal (CHUM), University Hospital, Brest | Intracranial Aneurysm | 01/23 | 04/23 | | |
NCT03031873: Evaluation of Susceptibility-weighted Magnetic Resonance Imaging and 4d-time-resolved Magnetic Resonance Angiography in Brain Arteriovenous Malformations |
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| Recruiting | N/A | 12 | Canada | MRI perfusion imaging | Ottawa Hospital Research Institute | Arteriovenous Malformations | 03/24 | 03/24 | | |
| Kapur, Atul |
INITIATE, NCT04163081: The Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments |
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| Recruiting | N/A | 1208 | Canada | Quit Card Intervention (QCI) | Ottawa Heart Institute Research Corporation, Canadian Institutes of Health Research (CIHR) | Nicotine Dependence, Cigarettes, Nicotine Withdrawal | 08/25 | 03/27 | | |
| Gallant, Jodi |
NCT02999022: Lithium for Fracture Treatment: a Double Blind Randomized Controlled Trial (LiFT) |
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| Recruiting | 2 | 160 | Canada | Lithium Carbonate, Lithium, Lactose Placebo, placebo | Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR) | Fractures | 12/24 | 06/25 | | |
COPE, NCT04274530: Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial |
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| Recruiting | N/A | 1000 | Canada, US | Cognitive Behavioural Therapy, CBT | McMaster University, Orthopaedic Trauma Association, Canadian Institutes of Health Research (CIHR) | Pain, Postoperative, Pain, Acute, Pain, Chronic, Fractures, Closed, Fractures, Open | 08/25 | 08/25 | | |
| MacFadden, Derek |
| Recruiting | 4 | 8000 | Europe, Canada, RoW | Cefazolin, Penicillin, Benzylpenicillin, Penicillin G, Clindamycin, Lincomycin, Vancomycin, Daptomycin, Effectiveness of early switch to oral antibiotics, Whole body FDG PET/CT Imaging | University of Melbourne, Berry Consultants, McGill University Health Centre/Research Institute of the McGill University Health Centre, Menzies School of Health Research, Aotearoa Clinical Trials, Queensland University of Technology, Sunnybrook Health Sciences Centre, Tan Tock Seng Hospital, Telethon Kids Institute, The Peter Doherty Institute for Infection and Immunity, The University of Queensland, UMC Utrecht, Radboud University Medical Center, King's College London, Rambam Health Care Campus, University College, London, Houston Medical Research Institute | Staphylococcus Aureus Bacteremia | 12/28 | 12/28 | | |
TAPER-V, NCT04138706: Initial Vancomycin Taper for the Prevention of Recurrent Clostridium Difficile Infection |
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| Active, not recruiting | 3 | 263 | Canada | Vancomycin, Placebos | McGill University Health Centre/Research Institute of the McGill University Health Centre, Canadian Institutes of Health Research (CIHR) | Clostridium Difficile Infection | 10/24 | 10/24 | | |
| Recruiting | N/A | 1440 | Canada | Clinical Decision Support Algorithm for Empiric Antibiotics in Sepsis, Decision Support Tool | Ottawa Hospital Research Institute, Canadian Institutes of Health Research (CIHR) | Sepsis, Bacterial Infections, Community-Acquired Infections, Hospital Infection | 03/25 | 06/25 | | |
| Recruiting | N/A | 550 | Canada, US | Start Antibiotics / Continue Antibiotics for treatment of bacteriuria, No Antibiotics for treatment of bacteriuria | Mount Sinai Hospital, Canada, Sault Area Hospital, Michael Garron Hospital, Unity Health Toronto, The Ottawa Hospital, Northwestern Memorial Hospital | Infectious Disease | 09/27 | 09/27 | | |
| Sackett-Fox, Krysten |
| Recruiting | 2/3 | 200 | Europe, Canada, US | Immediate mechanical thrombectomy(iMT) using EmboTrap Revascularization Device, EmboTrap III, Initial medical management (iMM) | Emory University, University of Calgary, University of Cincinnati, Heidelberg University, Children's Hospital Medical Center, Cincinnati | Cerebral Ischemia | 12/24 | 12/24 | | |
