| Recruiting | 3 | 500 | Canada, Japan, US, RoW | Hydrocortisone, sodium succinate, SOLU-CORTEF- hydrocortisone sodium succinate injection, Normal saline | Jerry Zimmerman, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Canadian Institutes of Health Research (CIHR), Canadian Critical Care Trials Group, Children's Hospital of Eastern Ontario | Septic Shock | 09/26 | 12/26 | | |