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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
HUCHET, Aymeri
BECOME-MB, NCT04074096 / 2021-006331-26: Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis	Active, not recruiting	2	10	Europe	Stereotaxic radiosurgery (SRS), Binimetinib Oral Tablet, Mektovi, Encorafenib Oral Capsule, Braftovi, Pembrolizumab, Keytruda	UNICANCER, European Association of Dermato Oncology, Pierre Fabre Medicament, Merck Sharp & Dohme LLC	Malignant Melanoma, BRAF V600 Mutation, Brain Metastases	04/25	04/29
IPANEMA, NCT06599879: Irradiation in Paediatrics: Neurocognition, Neuroimaging and Evaluation of Memory and Attention	Not yet recruiting	N/A	130	Europe	Neuropsychological assessments:	Institut Claudius Regaud	Brain Tumor, Pediatric	12/29	12/29

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
HUCHET, Aymeri
BECOME-MB, NCT04074096 / 2021-006331-26: Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis	Active, not recruiting	2	10	Europe	Stereotaxic radiosurgery (SRS), Binimetinib Oral Tablet, Mektovi, Encorafenib Oral Capsule, Braftovi, Pembrolizumab, Keytruda	UNICANCER, European Association of Dermato Oncology, Pierre Fabre Medicament, Merck Sharp & Dohme LLC	Malignant Melanoma, BRAF V600 Mutation, Brain Metastases	04/25	04/29
IPANEMA, NCT06599879: Irradiation in Paediatrics: Neurocognition, Neuroimaging and Evaluation of Memory and Attention	Not yet recruiting	N/A	130	Europe	Neuropsychological assessments:	Institut Claudius Regaud	Brain Tumor, Pediatric	12/29	12/29