Marrouche, Nassir F |
EDORA, NCT04704050: Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence |
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| Terminated | 4 | 22 | US | dronedarone 400 mg Oral Tablet, Multaq®, Placebo | Tulane University School of Medicine, University of Washington, Marrek, INC, Sanofi, Preventice, Mckesson | Atrial Fibrillation, Atrial Fibrillation Recurrent | 12/22 | 12/22 | | |
FROZEN-AF, NCT04133168: Boston Scientific's Cryoballoon in the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation |
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| Completed | N/A | 458 | Europe, Canada, US, RoW | Boston Scientific Cardiac Cryoablation System | Boston Scientific Corporation | Paroxysmal Atrial Fibrillation | 11/22 | 08/23 | | |
NCT04843371: PPG to Predict Ejection Fraction and Other Echographic Data in the General Population |
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| Recruiting | N/A | 500 | US | Photoplethysmography | Tulane University | Valvular Heart Disease, Pericardial Disease, Cardiomyopathies | 04/26 | 04/26 | | |
WEAICOR, NCT04605965: Wearables to Investigate the Long Term Cardiovascular and Behavioral Impacts of COVID-19 |
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| Active, not recruiting | N/A | 200 | US | | Tulane University, Biostrap | Covid19, Cardiovascular Complication, Behavioral Changes | 09/25 | 09/25 | | |
| Recruiting | N/A | 20 | US | | Tulane University | Atrial Fibrillation | 12/26 | 12/26 | | |
NCT04769310: Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study |
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| Recruiting | N/A | 120 | US | Cardiac and Brain MRI | Tulane University | Atrial Fibrillation, Stroke, Stroke, Cardiovascular, Vascular Cognitive Impairment, Strokes Thrombotic, Stroke, Ischemic | 01/26 | 01/26 | | |
NCT05014802: Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery |
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| Recruiting | N/A | 50 | US | | Tulane University | Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia | 08/26 | 08/26 | | |
| Recruiting | N/A | 10000 | US | Smartwatch | Tulane University, Samsung Electronics | Heart Diseases | 10/27 | 10/27 | | |
NCT04814420: Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study |
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| Recruiting | N/A | 60 | US | Delayed enhancement magnetic resonance imaging (DE-MRI) | Tulane University | Atrial Fibrillation, Obstructive Sleep Apnea | 12/25 | 12/25 | | |
TiPP, NCT04703166: Tulane iPredict, Prevent Study to Evaluate the Progression of Atrial Myopathy. |
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| Not yet recruiting | N/A | 300 | US | Samsung Galaxy Watch Active2 | Tulane University School of Medicine, Samsung, Preventice | Atrial Fibrillation | 12/27 | 12/27 | | |
LUX-Dx TRENDS, NCT04790344: Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System. |
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| Active, not recruiting | N/A | 525 | US | Investigational LUX-Dx ICM Implant | Boston Scientific Corporation | Heart Failure | 05/26 | 06/26 | | |
Thourani, Vinod |
| Recruiting | 3 | 3200 | Europe, Canada, US | Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy | Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center | Atrial Fibrillation, Stroke, Bleeding | 06/25 | 06/25 | | |
NCT02732691: JENAVALVE AS EFS TRIAL: Pericardial TAVR Aortic Stenosis Study |
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| Active, not recruiting | N/A | 68 | Europe, US, RoW | JenaValve Pericardial TAVR System | JenaValve Technology, Inc. | Aortic Valve Stenosis, Heart Valve Diseases, Heart Diseases, Cardiovascular Diseases, Ventricular Outflow Obstruction | 05/19 | 04/24 | | |
| Terminated | N/A | 12 | US | Edwards Cardioband System, Transcatheter mitral valve repair (TMVr), Guideline Directed Medical Therapy | Edwards Lifesciences | Functional Mitral Regurgitation, Mitral Regurgitation, Mitral Insufficiency | 07/19 | 09/22 | | |
NCT03539458: Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification |
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| Completed | N/A | 11 | US | Tendyne Mitral Valve System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Annular Calcification, Mitral Annulus Calcification, Cardiovascular Diseases, Valve Heart Disease, Heart Valve Diseases, Heart Valve Calcification, Mitral Valve Disease | 11/19 | 06/24 | | |
NCT02732704: THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study |
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| Active, not recruiting | N/A | 100 | Europe, US | JenaValve Pericardial TAVR System | JenaValve Technology, Inc. | Aortic Regurgitation | 08/22 | 09/27 | | |
| Active, not recruiting | N/A | 180 | US | JenaValve Trilogy Heart Valve System | JenaValve Technology, Inc. | Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency, Aortic Valve Disease | 08/23 | 08/28 | | |
| Active, not recruiting | N/A | 25 | US | HARPOON™ Beating Heart Mitral Valve Repair System | Edwards Lifesciences | Mitral Regurgitation | 12/27 | 12/27 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Recruiting | N/A | 15 | US | Transcatheter Tricuspid Valve Replacement | Trisol Medical | Tricuspid Regurgitation | 01/25 | 07/27 | | |
| Enrolling by invitation | N/A | 1300 | US | Decision Aid, Shared Decision Making Skills Training | Massachusetts General Hospital, University of California, San Francisco, University of Colorado, Denver, University of North Carolina, Chapel Hill, Emory University, University of Pennsylvania, University of Texas Southwestern Medical Center, University of Washington, Patient-Centered Outcomes Research Institute | Aortic Stenosis | 05/27 | 10/27 | | |
SUMMIT, NCT03433274: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation |
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| Recruiting | N/A | 958 | Canada, US | Tendyne Mitral Valve System, MitraClip System | Abbott Medical Devices | Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease, Heart, Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease | 05/24 | 06/28 | | |
| Recruiting | N/A | 50 | Canada, US | Cephea Mitral Valve System | Abbott Medical Devices | Mitral Regurgitation | 03/26 | 03/31 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
NCT05913908: EFS of the DUO System for Tricuspid Regurgitation |
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| Recruiting | N/A | 15 | US | DUO Transcatheter Tricuspid Coaptation Valve System, DUO System | CroiValve Limited | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases | 12/25 | 10/29 | | |
| Not yet recruiting | N/A | 50 | US | JenaValve Trilogy Heart Valve System | JenaValve Technology, Inc. | Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency, Aortic Valve Disease, Left Ventricular Dysfunction | 12/25 | 12/26 | | |
| Recruiting | N/A | 870 | Canada, US | Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | 12/27 | 12/31 | | |
| Not yet recruiting | N/A | 1016 | NA | Transcatheter Aortic Valve Replacement (TAVR) using Trilogy THV System, SAVR | JenaValve Technology, Inc. | Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency | 02/26 | 02/36 | | |
NCT06680427: Siegel™ Transcatheter Aortic Valve Replacement System (TAVR) Early Feasibility Study |
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| Recruiting | N/A | 15 | US | Siegel Transcatheter Aortic Valve (TAVR) | MiRus | Aortic Stenosis Symptomatic | 01/26 | 01/26 | | |
NCT03382457: Clinical Study of Edwards Cardioband FIT Valve Repair System |
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| Recruiting | N/A | 55 | US | Transcatheter Tricuspid Valve Repair, Edwards Cardioband Tricuspid Valve Repair | Edwards Lifesciences | Tricuspid Regurgitation | 12/26 | 12/31 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
PRIMARY, NCT05051033: Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds |
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| Recruiting | N/A | 450 | Europe, Canada, US | Mitral valve repair, Mitral valve surgery, Transcatheter edge-to-edge repair, TEER | Annetine Gelijns, National Heart, Lung, and Blood Institute (NHLBI) | Mitral Valve Regurgitation | 01/28 | 01/32 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
Kipperman, Robert |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
| Recruiting | N/A | 870 | Canada, US | Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | 12/27 | 12/31 | | |
NCT03382457: Clinical Study of Edwards Cardioband FIT Valve Repair System |
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| Recruiting | N/A | 55 | US | Transcatheter Tricuspid Valve Repair, Edwards Cardioband Tricuspid Valve Repair | Edwards Lifesciences | Tricuspid Regurgitation | 12/26 | 12/31 | | |
ENVISION, NCT05932615: IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation |
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| Enrolling by invitation | N/A | 1500 | Canada, US | Navitor Transcatheter Aortic Valve Implantation (TAVI) System, Any Commercially Available Transcatheter Aortic Valve (CAV) System | Abbott Medical Devices | Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder | 04/27 | 04/36 | | |
Zajarias, Alan |
| Active, not recruiting | N/A | 53 | US, RoW | Edwards SAPIEN 3 transcatheter valve, Model 9600TFX, TMVR | Edwards Lifesciences | Mitral Valve Insufficiency, Mitral Valve Disease, Mitral Valve Regurgitation, Heart Failure | 08/22 | 08/31 | | |
NCT02661451: Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD) |
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| Active, not recruiting | N/A | 178 | Europe, Canada, US | SAPIEN 3 THV, Optimal Heart Failure Therapy | Cardiovascular Research Foundation, New York, Cardialysis BV, Avania | Aortic Valve Stenosis | 02/23 | 02/25 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
| Recruiting | N/A | 870 | Canada, US | Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | 12/27 | 12/31 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
| Recruiting | N/A | 125 | Canada, US | Edwards SAPIEN 3/SAPIEN 3 Ultra THV | Edwards Lifesciences | Aortic Stenosis, Aortic Stenosis, Severe | 01/33 | 04/38 | | |
Brown, Christina |
POLAR BEAR, NCT04332822 / 2018-003889-14: A Randomized, Multicenter, Phase III Trial Comparing Treatment With R-mini-CHOP With R-mini-CHP + Polatuzumab Vedotin in Patients With Diffuse Large Cell B Cell Lymphoma |
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| Recruiting | 3 | 300 | Europe, RoW | R-pola-mini-CHP, R-mini-CHOP | Nordic Lymphoma Group, Roche Pharma AG | DLBCL, Diffuse Large B Cell Lymphoma | 12/25 | 12/28 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
Damiano, Marci |
NCT05014802: Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery |
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| Recruiting | N/A | 50 | US | | Tulane University | Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia | 08/26 | 08/26 | | |
Jr, Ralph Damiano |
NCT05014802: Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery |
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| Recruiting | N/A | 50 | US | | Tulane University | Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia | 08/26 | 08/26 | | |
Kachroo, Puja |
| Recruiting | N/A | 110 | US, RoW | NEXUS Aortic Stent Graft System | Endospan Ltd. | Aortic Dissection, Aortic Aneurysm, Intramural Hematoma, Penetrating Aortic Ulcer | 11/24 | 10/29 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Recruiting | N/A | 216 | US | ACCEL® Absorbable Hemostat Powder, Gelfoam® (Absorbable Gelatin Sponge, Pfizer Manufacturer Part Number 0342-01), SURGIFOAM® (Absorbable Gelatin Sponge, Manufacturer Part Number ETH1974). | Hemostasis, LLC | Hemostasis | 11/24 | 01/25 | | |
| Active, not recruiting | N/A | 115 | US | AMDS | Artivion Inc., Syneos Health | Acute Aortic Dissection | 12/23 | 12/29 | | |
| Active, not recruiting | N/A | 1070 | Europe, US | Edwards EVOQUE System, Transcatheter tricuspid valve replacement, Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure | 06/24 | 12/29 | | |
| Recruiting | N/A | 870 | Canada, US | Edwards PASCAL System, Transcatheter tricuspid valve repair (TTVr), Optimal Medical Therapy | Edwards Lifesciences | Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease | 12/27 | 12/31 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
NCT04124120: Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women |
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| Recruiting | N/A | 2000 | Europe, Canada, Japan, US, RoW | Single arterial graft, Multiple arterial grafting | Weill Medical College of Cornell University, New York Presbyterian Hospital, Sunnybrook Health Sciences Centre, Cedars-Sinai Medical Center, Columbia University, Duke University | Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting | 03/30 | 03/30 | | |
| Recruiting | N/A | 200 | Europe, US | Thoraflex Hybrid, RelayPro NBS | Vascutek Ltd., Bolton Medical | Thoracic Diseases, Aortic Aneurysm, Aortic Dissection, Thoracic Aortic Aneurysm, Thoracic Aortic Dissection | 12/35 | 12/36 | | |
Hermeyer, James |
NCT05076604: Effects of Microplegia on Transfusion Rates After Cardiac Surgery |
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| Completed | 4 | 314 | US | Cardioplegia Solution, Microplegic Solution No. 1 | Washington University School of Medicine, Quest Medical, Inc | Aortic Valve Disease, Mitral Valve Disease | 06/23 | 08/23 | | |
| Recruiting | 3 | 3200 | Europe, Canada, US | Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy | Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center | Atrial Fibrillation, Stroke, Bleeding | 06/25 | 06/25 | | |
| Recruiting | N/A | 216 | US | ACCEL® Absorbable Hemostat Powder, Gelfoam® (Absorbable Gelatin Sponge, Pfizer Manufacturer Part Number 0342-01), SURGIFOAM® (Absorbable Gelatin Sponge, Manufacturer Part Number ETH1974). | Hemostasis, LLC | Hemostasis | 11/24 | 01/25 | | |
| Active, not recruiting | N/A | 115 | US | AMDS | Artivion Inc., Syneos Health | Acute Aortic Dissection | 12/23 | 12/29 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
Kotkar, Kunal |
NCT05575128: Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures |
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| Recruiting | N/A | 100 | US | Behavioral activation, Medication optimzation, Care as usual | Washington University School of Medicine, National Institute of Mental Health (NIMH) | Cardiac Surgery, Older Adults, Depression, Anxiety | 11/24 | 03/25 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
Harris, Patrice |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |