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6 Active 5 Inactive 11 All	Not yet recruiting Recruiting Enrolling by invitation Active, not recruiting Available No longer recruiting	Industry lead sponsor Industry collaborator Coop Other	US Canada Japan Europe RoW	N/A 1 2 3 4	Highlight changes:- Show only changed items Enrollment:

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6 Trials

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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Satler, Lowell
NCT02661451: Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)	Active, not recruiting	N/A	178	Europe, Canada, US	SAPIEN 3 THV, Optimal Heart Failure Therapy	Cardiovascular Research Foundation, New York, Cardialysis BV, Avania	Aortic Valve Stenosis	02/23	02/25
CLASP IID, NCT03706833: Edwards PASCAL /IIF Pivotal Clinical Trial	Recruiting	N/A	1247	Europe, Canada, US	Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System	Edwards Lifesciences	Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation	01/25	04/30
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement	Active, not recruiting	N/A	1948	Canada, US	ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL	Boston Scientific Corporation	Aortic Stenosis	06/24	09/34
MITRAL-II, NCT04408430: The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).	Recruiting	N/A	210	US	Transseptal ViMAC, ViMAC	Mayra Guerrero	Mitral Annular Calcification, Mitral Stenosis, Mitral Regurgitation, Mitral Valve Disease	12/24	12/24
NCT05069558: Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion	Active, not recruiting	N/A	450	Europe, Canada, US	Investigational PFO Closure Device, Standard of Care PFO Closure Device	Occlutech International AB	Stroke, Patent Foramen Ovale, PFO	11/25	10/26
NCT03142152: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR	Recruiting	N/A	300	Europe, US	Carillon Mitral Contour System, Carillon, Percutaneous mitral valve repair, Guideline Directed Heart Failure Medication	Cardiac Dimensions, Inc.	Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases	12/26	12/30
Corso, Paul
No trials found