University Hospitals Dorset NHS Foundation Trust
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 3 Trials 
25 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
McCarthy, Helen
RAINBOW, NCT04061512: Rituximab and Ibrutinib (RI) Versus Dexamethasone, Rituximab and Cyclophosphamide (DRC) as Initial Therapy for Waldenström's Macroglobulinaemia

Recruiting
2/3
148
Europe
Dexamethasone, cyclophosphamide, rituximab, Rituximab, ibrutinib
University College, London, Janssen-Cilag Ltd.
Waldenstrom Macroglobulinemia
03/30
03/30
PembroWM, NCT03630042 / 2018-001767-23: Investigating the Safety and Efficacy of Rituximab and Pembrolizumab in Relapsed/Refractory Waldenström's Macroglobulinaemia

Completed
2
17
Europe
Pembrolizumab, Rituximab
University College, London, Merck Sharp & Dohme LLC
Waldenstrom Macroglobulinemia
09/21
02/24
REPAIR-MDS, NCT04997811: Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes

Recruiting
2
120
Europe
Sodium Valproate, Bezafibrate, Medroxyprogesterone, Danazol
Prof. Janet Dunn, Blood Cancer UK, Dudley Group NHS Foundation Trust, University of Birmingham, University of Manchester, King's College Hospital NHS Trust
Myelodysplastic Syndromes (MDS)
01/25
06/25
Sutton, Paul
REMACS, NCT05219058: Reconstruction in Extended MArgin Cancer Surgery

Recruiting
N/A
236
Europe
Biological mesh reconstruction, Myocutaneous flap reconstruction, Primary closure reconstruction
University Hospital Southampton NHS Foundation Trust, Salisbury NHS Foundation Trust, University of Southampton, Dorset County Hospital NHS Foundation Trust, The Leeds Teaching Hospitals NHS Trust, Mid Yorkshire Teaching NHS Trust, Newcastle-upon-Tyne Hospitals NHS Trust, University Hospitals Dorset NHS Foundation Trust, Somerset NHS Foundation Trust, Swansea Bay University Health Board, Portsmouth Hospitals NHS Trust, Hampshire Hospitals NHS Foundation Trust, Royal Devon and Exeter NHS Foundation Trust, Sussex Partnership NHS Foundation Trust, London North West Healthcare NHS Trust, Manchester University NHS Foundation Trust, NHS Greater Glasgow and Clyde, The Christie NHS Foundation Trust
Surgery--Complications, Pelvic Cancer, Abdominal Cancer, Quality of Life
09/26
01/28
King, Emma
PATHOS, NCT02215265 / 2014-003392-32: Post-operative Adjuvant Treatment for HPV-positive Tumours

Recruiting
3
1100
Europe, US, RoW
Cisplatin, Postoperative radiotherapy
Lisette Nixon, UNICANCER, AdventHealth, University of Leipzig, Princess Alexandra Hospital, Brisbane, Australia, Stanford University
Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer
10/26
04/27
VAROT, NCT05847556: Video Game Hearing Tests for Remote Monitoring of Ototoxicity

Recruiting
N/A
140
Europe
video game hearing tests, SSIN-VR, Spatial Speech in Noise-Virtual Reality, Audio-training, SSIN-Loc training, Spatial Speech in Noise and Localisation Training
Imperial College London
Aminoglycoside Toxicity, Aminoglycoside-Induced Hearing Loss, Hearing Loss, Video Games
09/23
09/23
Jordan, Andrew
OUTREACH, NCT03293147: Urine Analysis and Antihypertensive Treatment

Completed
N/A
200
Europe
HPLC-MS/MS-guided intervention, Standard care
University of Manchester, British Heart Foundation, Manchester Academic Health Science Centre, Omron Healthcare Co., Ltd.
Hypertension, Adherence, Medication
08/23
09/23
NCT06005220: SBD121, a Synbiotic Medical Food for RA Management

Recruiting
N/A
140
Europe, RoW
SBD121, Placebo
Solarea Bio, Inc
Rheumatoid Arthritis
06/25
07/25
ACTRN12611000102976: A randomised controlled trial of forearm strengthening exercises in osteoarthritis of the small joints of the hand

Not yet recruiting
N/A
66
 
Westmead Hospital, Department of Rheumatology
Primary osteoarthritis of small joints of the hand
 
 
Hamid, Mohamed
REPAIR-MDS, NCT04997811: Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes

Recruiting
2
120
Europe
Sodium Valproate, Bezafibrate, Medroxyprogesterone, Danazol
Prof. Janet Dunn, Blood Cancer UK, Dudley Group NHS Foundation Trust, University of Birmingham, University of Manchester, King's College Hospital NHS Trust
Myelodysplastic Syndromes (MDS)
01/25
06/25
NCT05270551: The Effect of Accelerated Rehabilitation After Anterior Cruciate Ligament Reconstruction With and Without Suture Tape Reinforcement

Not yet recruiting
N/A
114
NA
ACL Reconstruction
Assiut University
ACL Injury
03/23
05/23
NCT05420740: Impact of Aerobika OPEP in Improving Small Airway Parameters in COPD

Completed
N/A
53
RoW
Aerobika OPEP
National University of Malaysia
COPD
04/23
06/23
NCT06162429: Medical Thoracoscopy With Flexible Bronchoscopy Versus Semi-Rigid Pleuroscope in Pleural Effusion (FLEXPLEUR)

Completed
N/A
188
RoW
Flexible Bronchoscopy, Semi-Rigid Pleuroscopy
National University of Malaysia
Pleural Effusion
11/24
11/24
VR-STICH, NCT06247800: Virtual Reality: Distraction During Small Bore Intercostal Chest Drain Insertion

Recruiting
N/A
80
RoW
Virtual Reality Device, Without virtual reality
National University of Malaysia
Pleural Effusion
12/26
12/26
SENSHIP, NCT06314620: Normal Saline Flushing With And Without Heparin Lock In Maintaining Small Bore Intercostal Chest Catheter (ICC) Patency

Recruiting
N/A
40
RoW
Heparin saline lock, Without heparin saline lock
National University of Malaysia
Pleural Effusion
03/27
06/27
SyProNAC, NCT06377410: Efficacy & Safety of Dry Powder Ivy Extract (Syrup Prospan) Versus NAC Among COPD Patients

Recruiting
N/A
100
RoW
Syrup Prospan, N-Acetylcysteine
National University of Malaysia
Chronic Obstructive Pulmonary Disease
11/26
11/26
CASPAM, NCT06564896: Conventional CPAP Airsense 10 VS Portable Air-Mini CPAP For Obstructive Sleep Apnea

Recruiting
N/A
50
RoW
CPAP Airsense 10 vs Air-Mini
National University of Malaysia
Obstructive Sleep Apnea
12/26
01/27
NCT05903417: Pleural Irrigation With Normal Saline Versus Intrapleural Fibrinolytic

Recruiting
N/A
78
RoW
Intrapleural fibrinolytic with alteplase 5mg and pulmozyme 5 mg, Saline irrigation with 250 mls normal saline (over 1 hour)
National University of Malaysia
Pleural Infection
10/25
10/25
NCT05087901: Multifocal Electroretinography Before and After Silicone Oil Removal

Recruiting
N/A
30
RoW
Multifocal electroretinogram
Minia University
Silicone Oil Filled Eyes
01/22
03/22
Harding, Stephen
E-Drone, NCT04990843: Transforming the Energy Demand of Supply Chains Through Integrated UAV-to-land Logistics for 2030

Completed
N/A
24
Europe
Bournemouth University, University of Southampton, University College, London, University of Leeds
Health Knowledge, Attitudes, Practice
12/23
12/23
Grigsby, Stephanie
NCT04059822: Slow and Deep Breathing to Lower Blood Pressure in Women With Pregnancy-induced Hypertension

Suspended
N/A
67
Europe
Slow and deep breathing
Bournemouth University
Pregnancy-Induced Hypertension
12/26
12/26
SMA-NBS, NCT05481164: Newborn Screening for Spinal Muscular Atrophy

Recruiting
N/A
45000
Europe
University of Oxford, Novartis Gene Therapies, Hoffmann-La Roche, Oxford University Hospitals NHS Trust
Muscular Atrophy, Spinal
03/25
03/25
Research, Head of
REPAIR-MDS, NCT04997811: Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes

Recruiting
2
120
Europe
Sodium Valproate, Bezafibrate, Medroxyprogesterone, Danazol
Prof. Janet Dunn, Blood Cancer UK, Dudley Group NHS Foundation Trust, University of Birmingham, University of Manchester, King's College Hospital NHS Trust
Myelodysplastic Syndromes (MDS)
01/25
06/25
Hockings, Catherine
REPAIR-MDS, NCT04997811: Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes

Recruiting
2
120
Europe
Sodium Valproate, Bezafibrate, Medroxyprogesterone, Danazol
Prof. Janet Dunn, Blood Cancer UK, Dudley Group NHS Foundation Trust, University of Birmingham, University of Manchester, King's College Hospital NHS Trust
Myelodysplastic Syndromes (MDS)
01/25
06/25
Zoysa, Neil De
HoT, NCT05604963: Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers

Recruiting
N/A
456
Europe
Total Thyroidectomy, Hemithyroidectomy
University College, London, National Institute for Health Research, United Kingdom
Differentiated Thyroid Cancer
07/28
07/31

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