| Shelton, Richard C |
| Not yet recruiting | 4 | 2726 | Canada, US | Cariprazine, Vraylar, Aripiprazole/Escitalopram combination, Abilify/ Lexapro, Quetiapine, Seroquel, Lurasidone, Latuda | Massachusetts General Hospital, Patient-Centered Outcomes Research Institute | Bipolar I Disorder, Depression | 02/30 | 02/30 | | |
NCT05169710 / 2021-002126-24: A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder. |
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| Terminated | 3 | 83 | Europe, Canada, Japan, US | SEP-4199 CR 200 mg, SEP-4199 CR 400 mg, Placebo | Sumitomo Pharma America, Inc., Sunovion Pharmaceuticals Inc. | Depressive Episodes, Bipolar I Depression | 10/23 | 10/23 | | |
NCT05729373: A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder |
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| Recruiting | 2/3 | 434 | Europe, Japan, US | SEP-363856, Placebo | Otsuka Pharmaceutical Development & Commercialization, Inc. | Generalized Anxiety Disorder | 02/26 | 02/26 | | |
ENLIGHTEN, NCT05113771: A Biomarker-Guided, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With Treatment-Resistant Depression |
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| Completed | 2 | 197 | Canada, US | Liafensine, Placebo | Denovo Biopharma LLC | Treatment Resistant Depression | 02/24 | 03/24 | | |
NCT04923685: MicroRNA Correlates of Childhood Maltreatment and Suicidality |
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| Recruiting | N/A | 450 | US | Trier Social Stress Test, TSST | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideation | 09/25 | 09/25 | | |
NCT05437588: Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents |
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| Recruiting | N/A | 240 | US | Genetic testing | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD, Depression, Depression, Teen, Depression and Suicide, Depression in Adolescence, Suicide | 06/27 | 06/27 | | |
RECOVER, NCT03887715: A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression |
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| Recruiting | N/A | 6800 | US | Vagus Nerve Stimulation (VNS), VNS | LivaNova | Treatment Resistant Depression | 02/28 | 12/30 | | |
| Dwivedi, Yogesh |
NCT04923685: MicroRNA Correlates of Childhood Maltreatment and Suicidality |
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| Recruiting | N/A | 450 | US | Trier Social Stress Test, TSST | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideation | 09/25 | 09/25 | | |
NCT05437588: Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents |
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| Recruiting | N/A | 240 | US | Genetic testing | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD, Depression, Depression, Teen, Depression and Suicide, Depression in Adolescence, Suicide | 06/27 | 06/27 | | |
| Stewart, Allison |
NCT04923685: MicroRNA Correlates of Childhood Maltreatment and Suicidality |
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| Recruiting | N/A | 450 | US | Trier Social Stress Test, TSST | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideation | 09/25 | 09/25 | | |
| McCrory, Brittany |
NCT05437588: Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents |
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| Recruiting | N/A | 240 | US | Genetic testing | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD, Depression, Depression, Teen, Depression and Suicide, Depression in Adolescence, Suicide | 06/27 | 06/27 | | |
| Alldredge, Annalyse M |
NCT04923685: MicroRNA Correlates of Childhood Maltreatment and Suicidality |
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| Recruiting | N/A | 450 | US | Trier Social Stress Test, TSST | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideation | 09/25 | 09/25 | | |
NCT05437588: Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents |
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| Recruiting | N/A | 240 | US | Genetic testing | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD, Depression, Depression, Teen, Depression and Suicide, Depression in Adolescence, Suicide | 06/27 | 06/27 | | |
| Burns, Jennifer |
NCT05437588: Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents |
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| Recruiting | N/A | 240 | US | Genetic testing | University of Alabama at Birmingham, National Institute of Mental Health (NIMH) | Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD, Depression, Depression, Teen, Depression and Suicide, Depression in Adolescence, Suicide | 06/27 | 06/27 | | |
