La Paz University Hospital Trials

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Primary compl

Study compl

Canales, Miguel

ECHELON-3, NCT04404283 / 2020-002686-33: Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

Jan 2023 - Dec 2023 : From:ECHELON-3 trial in combination with brentuximab vedotin and rituximab for r/r DLBCL

Active, not recruiting

241

Europe, Canada, US, RoW

Brentuximab vedotin, Rituximab, Lenalidomide, Placebo

Seagen, a wholly owned subsidiary of Pfizer

Diffuse Large B-cell Lymphoma

11/25

CRESCENDO, NCT06072131: To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

Recruiting

504

Europe, Canada, US, RoW

Belinostat Injection, Beleodaq®, Pralatrexate Injection, Folotyn®, CHOP, Cyclophosphamide, Hydroxydaunorubicin (doxorubicin), Oncovin (vincristine), and Prednisone, COP, Cyclophosphamide, Oncovin (vincristine), and Prednisone

Acrotech Biopharma Inc.

Peripheral T Cell Lymphoma

07/30

11/30

NCT04442022 / 2020-000605-84: A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) with or Without Selinexor in Patients with Relapsed/Refractory Diffuse Large B-cell Lymphoma

Recruiting

2/3

501

Europe, US, RoW

Selinexor (combination therapy), Placebo matching for Selinexor (combination therapy), Rituximab (combination therapy), Gemcitabine (combination therapy), Dexamethasone (combination therapy), Cisplatin (combination therapy), Selinexor (continuous therapy), Placebo matching for Selinexor (continuous therapy)

Karyopharm Therapeutics Inc

Relapsed/refractory Diffuse Large B-cell Lymphoma

12/25

SGN35-032, NCT04569032 / 2020-002336-74: A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Active, not recruiting

Europe, US, RoW

brentuximab vedotin, ADCETRIS, cyclophosphamide, doxorubicin, prednisone

Seagen, a wholly owned subsidiary of Pfizer

Peripheral T-cell Lymphoma

05/24

12/25

RESILIENCE, NCT05223413: REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs

Recruiting

N/A

608

Europe

RIPC, Simulated RIPC (Sham)

Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, European Commission

Anthracycline-induced Cardiac Toxicity, Lymphoma

06/26

12/26

Feliu, Jaime

ASPIRE, NCT05254171: Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

Recruiting

2/3

600

Europe, US, RoW

SBP-101, ivospemin, Nab-paclitaxel, Abraxane, Gemcitabine, Gemzar, Placebo

Panbela Therapeutics, Inc.

Pancreatic Cancer Metastatic, Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Stage IV

08/26

01/27

IMC-C103C-101, NCT03973333: Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab

Withdrawn

1/2

Europe, US

IMC-C103C, Atezolizumab, TECENTRIQ

Immunocore Ltd

Select Advanced Solid Tumors

09/23

PAUF, NCT05141149 / 2021-000682-32: First in Human Phase1/2a Clinical Trial of Anti- Monoclonal Antibody PBP1510 in Patients With Pancreatic Cancer

Recruiting

1/2

Europe, US, RoW

PBP1510 (400mg/16mL), Gemcitabine (1000 mg/m^2)

Prestige Biopharma Limited, Prestige Biopharma Limited

Pancreatic Cancer

02/26

12/26

CHEMOFAST, NCT04247464: Short-term Fasting as an Enhancer of Chemotherapy: Pilot Clinical Study on Colorectal Carcinoma Patients

Completed

N/A

Europe

Fasting

IMDEA Food, Hospital Infanta Sofia, Hospital Universitario La Paz

Fasting

02/23

Espinosa, Enrique

EBIN, NCT03235245 / 2017-002887-42: Immunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and Binimetinib

Active, not recruiting

271

Europe

Nivolumab + Ipilimumab, Encorafenib + Binimetinib

European Organisation for Research and Treatment of Cancer - EORTC

Unresectable Stage III Melanoma, Stage IV Melanoma

10/23

01/27

OCULE-01, NCT06717126: A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma

Recruiting

Europe

roginolisib, IOA-244, Investigator choice of standard therapy

iOnctura

Uveal Melanoma, Ocular Melanoma

12/27

12/28

Gomez, Carmen

EXO, NCT05563402: "Evaluation of Usability and Safety of the Self-balancing Walking System Atalante in Patients With Multiple Sclerosis"

Completed

N/A

Europe

Atalante

Multiple Sclerosis Center of Catalonia

Multiple Sclerosis, Ataxia, Paraplegia

12/22

03/23

NCT06615947: Conventional Multidisciplinary Gait Rehabilitation VR Robotic Self-balancing Based Gait Rehabilitation

Enrolling by invitation

N/A

Europe

Robotic gait training, Robotic, Atalante Gait Training, tRHB, Physical therapy, gait training

Multiple Sclerosis Center of Catalonia

Multiple Sclerosis, Gait Disorders, Neurologic

03/25

Sanchez, Andres F

innovaTV 301, NCT04697628 / 2019-001655-39: Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

Active, not recruiting

502

Europe, Canada, Japan, US, RoW

tisotumab vedotin, TIVDAK, PF-08046057, topotecan, vinorelbine, gemcitabine, irinotecan, pemetrexed

Seagen, a wholly owned subsidiary of Pfizer, Genmab

Cervical Cancer

07/23

05/26

ABX464-106, NCT05507216: ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2

Recruiting

612

Europe, Canada, Japan, US, RoW

ABX464, Obefazimod, Placebo

Abivax S.A.

Ulcerative Colitis

03/25

04/25

ABTECT, NCT05535946: - Maintenance

Recruiting

1050

Europe, Canada, Japan, US, RoW

ABX464, Obefazimod, Placebo

Abivax S.A.

Ulcerative Colitis

01/26

01/30

CAMPFIRE, NCT05999994: A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Recruiting

105

Europe, Japan, US, RoW

Ramucirumab, LY3009806, Cyclophosphamide, Vinorelbine, Gemcitabine, LY188011, Docetaxel, Abemaciclib, LY2835219, Irinotecan, Temozolomide

Eli Lilly and Company

Neoplasms, Child, Adolescent

05/27

NCT05440786 / 2021-004734-11: CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Active, not recruiting

Europe, Japan, US, RoW

Abemaciclib, LY2835219, Irinotecan, Temozolomide

Eli Lilly and Company

Sarcoma, Ewing, Neoplasm Metastasis

01/25

09/28

STRO-002-GM1, NCT03748186: Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers

Completed

136

Europe, US

STRO-002

Sutro Biopharma, Inc.

Ovarian Cancer, Ovarian Carcinoma, Ovary Cancer, Endometrial Cancer, Endometrioid Adenocarcinoma, Fallopian Tube Cancer, Primary Peritoneal Carcinoma

06/24

Ruiz, Elena SÃ¡ez

IMPRICA, NCT03803280: Implementation of Enhanced Recovery Protocol in Spain

Recruiting

N/A

2000

Europe

ERAS program

Grupo Español de Rehabilitación Multimodal, Instituto de Investigación Sanitaria Aragón, Instituto Aragones de Ciencias de la Salud

Major Surgery

07/22

12/22

LESAS, NCT04305314: Long-term Enlarged Survival After an Enhanced Recovery Protocol ().

Recruiting

N/A

750

Europe

PRI (Enhanced Recovery after surgery protocol)

Grupo Español de Rehabilitación Multimodal, Instituto de Salud Carlos III, Instituto de Investigación Sanitaria Aragón

Major Surgery

09/22

09/25

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

FLOE, NCT06047132: PREDICTIVE ABILITY OF A PANEL OF BIOMARKERS IN SALIVA IN HEALTHY AND PERIODONTALLY AFFECTED SUBJECTS

Active, not recruiting

N/A

100

Europe

Salivaru biomarkers

Universidad Complutense de Madrid

Periodontitis, Saliva, Biomarkers

06/24

01/25

LeakyBraInCS, NCT05950009: Relationship Between Major Depression and Periodontal Diseases

Recruiting

N/A

122

Europe

No intervention (observational studies)

Universidad Complutense de Madrid, Ministerio de Economía y Competitividad, Spain

Major Depressive Disorder, Periodontitis

01/26

03/26

LeakBrainRCT, NCT06036472: Impact of Periodontal Therapy on Mental Health Parameters

Recruiting

N/A

Europe

Standard periodontal therapy (steps 1 & 2), supragingival debridement with anesthesia (step 1)

Universidad Complutense de Madrid, Ministerio de Economía y Competitividad, Spain

Periodontitis, Depression

01/26

Alonso, Marta

NCT06214052: VH4524184 Proof-of-Concept in Treatment-Naïve Adults Living With HIV-1

Completed

Europe, Canada, US, RoW

VH4524184, Placebo

ViiV Healthcare, GlaxoSmithKline

HIV Infections

06/24

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Borobia, Alberto

VORIGENPHARM, NCT04238884: Effectiveness and Efficiency of a Voriconazole Preemptive Genotyping Strategy

Recruiting

146

Europe

Voriconazole preemptive genotyping strategy, Voriconazole clinical practice

Instituto de Investigación Hospital Universitario La Paz

Invasive Fungal Infections

01/20

12/22

DermAtOmics, NCT05692843: Optimization of Cyclosporin in Atopic Dermatitis Through Multiomic Predictive Models of Treatment Response

Recruiting

100

Europe

Cyclosporin A, Prospective, Follow-up of Cyclospoin treatment already started, Ambispective

Instituto de Investigación Hospital Universitario La Paz

Atopic Dermatitis

11/23

07/24

Gutierrez, Juan

POTHeR, NCT06911736: Effect of the Postoperative Trendelenburg Position on Chronic Subdural Hematoma Recurrence

Recruiting

N/A

254

RoW

Trendelenburg position

Universidad de Antioquia

Chronic Subdural Hematoma, Trendelenburg, Recurrence, Mortality, Prognosis, Clinical Trials

02/25

04/27

Bravo, Maria Fe

AGES-Mind, NCT03309475: Effectiveness of a Mindfulness-based Group Training Addressing Social Cognition in First Episode Psychosis

Completed

N/A

Europe

SocialMIND, Mindfulness-based social cognition training, Mindfulness-based social cognition group training, MB-SCT, Psychoeducational multicomponent intervention, PMI, Structured psychoeducational group, Psychoeducational group, Psychoeducation group, Psychosocial treatment, Psychotropic treatment, Drug treatment

Instituto de Investigación Hospital Universitario La Paz, Carlos III Health Institute, European Regional Development Fund

Schizophrenia and Disorders With Psychotic Features, Psychotic Episode

01/23

Munoz, Ainoa

AGES-Mind, NCT03309475: Effectiveness of a Mindfulness-based Group Training Addressing Social Cognition in First Episode Psychosis

Completed

N/A

Europe

Instituto de Investigación Hospital Universitario La Paz, Carlos III Health Institute, European Regional Development Fund

Schizophrenia and Disorders With Psychotic Features, Psychotic Episode

01/23

Gimeno, Blanca Fuentes

AMASCIS-02, NCT04280003: Allogeneic Adipose Tissue-derived Mesenchymal Stem Cells in Ischemic Stroke

Recruiting

Europe

Alogenic adipose tissue-derived stem cells, Placebo solution

Instituto de Investigación Hospital Universitario La Paz

Ischemic Stroke, Adipose Tissue-derived Stem Cell, Functional Status

07/23

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Tension, NCT03094715: Efficacy and Safety of Thrombectomy in Stroke With Extended Lesion and Extended Time Window

Terminated

N/A

253

Europe, Canada, RoW

Thrombectomy, Mechanical thrombectomy, Best medical care, Control group

University Hospital Heidelberg, Karolinska University Hospital, Eppdata GmbH Hamburg, Germany, Aarhus University Hospital, Medical University Innsbruck, Groupe Hospitalier Pitie-Salpetriere, Oslo University Hospital, University Hospital, Martin, Charles University, Czech Republic, Hospices Civils de Lyon, CHU de Reims, Epidemiological and Clinical Research Information Network, STROKE ALLIANCE FOR EUROPE, International Consortium for Health Outcome Measurement, Inc., Europan Society for Minimally Invasive Neurological Therapy, Universitätsklinikum Hamburg-Eppendorf

Stroke, Acute, Cerebral Stroke, Cerebrovascular Stroke, Apoplexy; Brain

05/23

11/23

NCT05871502: Glycemia and Ischemia Reperfusion Brain Injury in Patients With Acute Cerebral Infarction Treated With Mechanical Thrombectomy

Recruiting

N/A

100

Europe

Subcutaneous blood glucose monitoring device

Instituto de Investigación Hospital Universitario La Paz

Cerebral Infarction

04/25

GÃ³mez, Lydia de la Fuente

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Iborra, Cristian Sempere

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

LeciÃ±ana, MarÃa Alonso de

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

ZÃºÃ±iga, Raquel GutiÃ©rrez

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

TÃ ppero, JosÃ© LÃ³pez

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Yvorra, Silvia Pastor

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Bobillo, Ricardo Riguel

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

ARIES, NCT05486221: Atrial Imaging and Cardiac Rhythm In Embolic Stroke

Recruiting

N/A

150

Europe

Extensive cardiologic work-up

Instituto de Investigación Hospital Universitario La Paz, Hospital Universitario La Paz, Proyecto Ictus- Grupo Estudio Enfermedades CerebroVasculares de la Sociedad Española de Neurología

Cryptogenic Stroke, Atrial Fibrillation, Atrial Dilatation, Stroke, Ischemic

12/22

KOALA-IS, NCT05486351: Keeping Oral o Parental AnticoaguLation in the Acute Phase of Cardioembolic Ischemic Stroke

Recruiting

N/A

318

Europe

Observation

Instituto de Investigación Hospital Universitario La Paz, Hospital Universitario La Paz, Daiichi Sankyo, Inc., Fundación Freno al ICTUS

Cardioembolic Stroke, Anticoagulant Therapy, Stroke Recurrence, Haemorrhagic Transformation Stroke

12/23

Ares, Gerardo Ruiz

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Pardo, Jorge RodrÃguez

NCT05357989 / 2022-001542-38: A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD

Completed

523

Europe, US

buntanetap/posiphen, Posiphen Tartrate, ANVS401, Placebo

Annovis Bio Inc., TFS Trial Form Support

Parkinson's Disease, Idiopathic

12/23

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Bueno, Nereida

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Blanco, Paloma

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Soria-Juan, Barbara

NCT04741321: Validation of VascuQol-6 Spanish Version

Recruiting

N/A

104

Europe

VascuQol-6 questionnaire Spanish version

Instituto de InvestigaciÃ³n Sanitaria de la FundaciÃ³n JimÃ©nez DÃaz

Peripheral Artery Disease

02/21

Arcas, Mireia

NOMA, NCT04466007: Safety and Efficacy of Allogeneic Adipose Tissue Mesenchymal Stem Cells in Diabetic Patients With Critical Limb Ischemia

Completed

Europe

High dose allogeneic mesenchymal stromal cells, Low dose allogeneic mesenchymal stromal cells, Placebos

Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Clinica Universidad de Navarra, Universidad de Navarra, Hospital Universitario La Paz, Gregorio Marañón Hospital, Hospital Clínico Universitario de Valladolid, Hospital Universitario Virgen de la Arrixaca, University of Salamanca, Hospital General Universitario de Alicante, Hospital Universitario La Fe, Hospital Victoria Eugenia Cruz Roja Española

Limb Ischemia, Diabetic Foot

05/24

12/24

NCT06144567: Response to Upadacitinib of Enthesitis Evaluated by Ultrasound in Patients With Psoriatic Arthritis

Not yet recruiting

N/A

Europe

Upadacitinib, Rinvoq

Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Hospital Universitario de Móstoles

Psoriatic Arthritis

06/26

Jurado, Alfonso

RollerCoaster, NCT04181268 / 2011-002445-36: ROtational Atherectomy, Lithotripsy or LasER for the Treatment of CAlcified STEnosis

Recruiting

N/A

150

Europe

Percutaneous coronary Intervention

Hospital Universitario La Paz

Coronary Artery Disease

11/23

ASSIST, NCT06939738: Artificial Intelligence Scalable Solution for ST Myocardial Infarction

Recruiting

N/A

500

Europe

Idoven 1903 S.L.

Acute Myocardial Infarction (AMI)

11/25

Galeote, Guillermo

CRATER, NCT05353946: Coronary Rotational Atherectomy Elective vs. Bailout in Severely Calcified Lesions and Chronic Renal Failure

Recruiting

N/A

124

Europe

Percutaneous coronary intervention (PCI)

Guillermo Galeote; MD, PhD

Coronary Artery Disease, Chronic Renal Failure

12/22

12/23

Gonzalez, Patricio

TREX, NCT03089905: A Study to Compare the Long-term Outcomes After Two Different Anaesthetics

Active, not recruiting

450

Europe, US, RoW

Sevoflurane, Sevorane, Remifentanil, Ultiva, Dexmedetomidine, Precedex, Dexmedetomidine Ever Pharma

Murdoch Childrens Research Institute, Sydney Children's Hospitals Network, Baylor College of Medicine, Boston Children's Hospital, The Cleveland Clinic, University of Texas, Southwestern Medical Center at Dallas, Royal Children's Hospital, Children's Hospital of Philadelphia, Queensland Children's Hospital, Perth Children's Hospital, Women and Children's Hospital, Istituto Giannina Gaslini, Flinders Medical Centre

Anesthesia, Neurotoxicity, Child Development

03/26

06/26

Mannucci, Alessandro

AACRC, NCT06342440: Early Detection of Advanced Adenomas and Colorectal Cancer

Recruiting

N/A

2000

Europe, Japan, US, RoW

DENEB, DENEB (DEtection of colorectal NEoplasias in Blood)

City of Hope Medical Center

Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenocarcinoma, Colorectal Disorders, Colorectal Dysplasia, Colorectal Cancer Stage I, Colorectal Cancer Stage II, Colorectal Cancer Stage III, Colorectal Cancer Stage IV, Colorectal Neoplasms Malignant, Colorectal Serrated Adenocarcinoma, Colorectal Adenoma With Severe Dysplasia, Colorectal Adenoma With Mild Dysplasia, Colorectal Adenoma With Moderate Dysplasia, Colorectal Adenoma and Carcinoma 1, Colorectal Adenomatous Polyp, Colorectal Adenocarcinoma Metastatic in the Liver

12/25

T1CR, NCT06314971: Predicting Local and Distant Recurrence in T1 Colorectal Cancer

Recruiting

N/A

200

Europe, Japan, US

Tw1CE, T1 Colorectal cancer rEcurrence (Tw1CE)

City of Hope Medical Center

Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I, Colorectal Neoplasms Malignant, Colorectal Cancer Recurrent

06/26

CENSURE, NCT06314958: Stage II/III Colorectal Cancer Recurrence

Recruiting

N/A

400

Europe, US, RoW

CENSURE, CENSURE (CpG mEthylation-based epigeNetic SignatURE)

City of Hope Medical Center

Colorectal Cancer, Colorectal Adenocarcinoma, Colorectal Cancer Stage II, Colorectal Cancer Stage III, Colorectal Cancer Recurrent

06/25

PCDC, NCT06388967: Pancreatic Cancer Detection Consortium

Recruiting

N/A

2000

Japan, US, RoW

PANcreatic cancer Exosome Early detectiON (PANXEON), PANXEON (PANcreatic cancer Exosome Early detectiON)

City of Hope Medical Center

Pancreatic Cancer, Pancreatic Carcinoma, Pancreatic Adenocarcinoma, Pancreatic Ductal Adenocarcinoma, Pancreatic Neoplasms, Pancreatic Cancer Stage I, Pancreatic Cancer Stage, Pancreatic Cancer Resectable, Pancreatic Cancer Stage 0, Pancreatic Cancer Stage II, Pancreatic Cancer Stage III, Pancreatic Cancer, Adult, Pancreatic Cancer Non-resectable

11/25

ENCODE, NCT06342401: Early Onset Colorectal Cancer Detection

Recruiting

N/A

400

Europe, Japan, US

ENCODE, ENCODE (Early oNset COlorectal cancer DEtection)

City of Hope Medical Center

Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I, Colorectal Cancer Stage IV, Colorectal Cancer Stage II, Colorectal Cancer Stage III, Colorectal Neoplasms Malignant

10/25

ENCORE, NCT06271980: Early-Onset Colorectal Cancer Recurrence

Completed

N/A

177

ENCORE, ENCORE (Early oNset COlorectal cancer REcurrence)

City of Hope Medical Center, IRCCS San Raffaele Hospital, Milan, Italy, Institute of Biomedical Research of Salamanca, Salamanca, Spain

Colorectal Cancer Recurrent, Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I, Colorectal Cancer Stage II, Colorectal Cancer Stage III

02/24

EMERALD, NCT06381583: A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma

Completed

N/A

658

EMERALD (Esophageal MicroRNAs for BaRRett's esophagus, Adenocarcinoma, and Dysplasia)

City of Hope Medical Center

Esophagus Cancer, Esophageal Cancer Stage, Esophageal Cancer, Esophageal Neoplasms, Esophagus Adenocarcinoma, Esophagus, Barrett, Barrett Esophagus, Barrett Adenocarcinoma, Barrett Epithelium, Barretts Esophagus With Dysplasia, Barrett's Esophagus Without Dysplasia, Barretts Esophagus With High Grade Dysplasia, Barretts Esophagus With Low Grade Dysplasia, Barrett Esophagus, Long-Segment, Barrett's Esophagus With Dysplasia, Unspecified, Barrett's Esophagus With Esophagitis, Gastroesophageal Reflux, Reflux Disease, Esophageal Adenocarcinoma, Esophageal Dysplasia, Esophageal Neoplasms Malignant

04/24

LYNX-EYE, NCT06708429: Lynch Syndrome X-Talk of Enteral Mucosa With Immune System

Recruiting

N/A

300

Europe, US

LYNX EYE (Lynch syndrome X-Talk of Enteral mucosa with Immune System)

San Raffaele University

Lynch Syndrome, Lynch Syndrome I, Lynch Syndrome II, Lynch Syndrome I (Site-specific Colonic Cancer), HNPCC, HNPCC Gene Mutation, Hereditary Cancer Syndrome, Hereditary Cancer, MLH1 Gene Mutation, MLH1 Gene Deletion+Duplication, MLH1 Loss of Expression, MLH1 Gene Inactivation, MSH2 Gene Mutation, MSH2 Gene Deletion+Duplication, MSH2 Loss of Expression, MSH2 Gene Inactivation, MSH6 Gene Mutation, MSH6 Loss of Expression, MSH6 Gene Inactivation, PMS2 Gene Mutation, PMS2 Gene Inactivation, PMS2 Loss of Expression

06/33

06/34

DEMETRA, NCT05732623: Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

Recruiting

N/A

2300

Europe, US

Semi Quantitative Food Frequency Questionnaire (SQFFQ)

San Raffaele University, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy, Ospedale Civile Guglielmo da Saliceto, Piacenza, Italy, Centro di Riferimento Oncologico di Aviano, Aviano, Italy, Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Bari, Italy, Gastroenterology Unit, University Hospital of Padova, Padova, Italy, Clinical Gastroenterology Unit, Azienda Ospedaliero Universitaria Careggi, Firenze, Italy, IRCCS Arcispedale S. Maria Nuova - Azienda Ospedaliera di Reggio Emilia, Reggio Emilia, Italy, Azienda Ospedaliera San Gerardo di Monza, Monza, Italy, Azienda ULSS5 Polesana, Rovigo, Italy, Istituto Tumori Regina Elena - IRCCS IFO, Roma, Italy, University Hospital of Padova, Padova, Italy, IRCCS De Bellis, Castellana Grotte, Italy, University Hospital HELIOS Klinikum Wuppertal, Center for Hereditary Tumors, University of Witten-Herdecke, Wuppertal, Germany, Hospital of the University of Munich (LMU), Campus Großhadern, Munich, Germany, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain, Helsinki University Hospital, Helsinki, Finland, Oslo University Hospital (OUS), Institute for Cancer Genetics and Informatics Norwegian Radium Hospital, Oslo, Norway, Department of Medicine University of Chicago Medicine, Illinois, USA, University of Colorado Hospital, CO, USA, University of Michigan Ann Arbor, Michigan, USA, Columbia University Irving Medical Center, New York, NY, The James Comprehensive Cancer Center, Columbus, OH, USA, Ohio State University, Cleveland Clinic Main Campus, Cleveland, OH, USA, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia

Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk Reduction

01/30

01/35

Borobia-Perez, Alberto M

NCT05965414: Safety and Pharmacokinetics of Single Ascending Doses and Multiple Ascending Doses of CS6253 in Healthy Volunteers

Completed

Europe

CS6253 Solution for Injection, Placebo

Artery Therapeutics, Inc., National Institute on Aging (NIA)

Alzheimer's Disease

07/24

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Canales, Miguel

ECHELON-3, NCT04404283 / 2020-002686-33: Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

Jan 2023 - Dec 2023 : From:ECHELON-3 trial in combination with brentuximab vedotin and rituximab for r/r DLBCL

Active, not recruiting

241

Europe, Canada, US, RoW

Brentuximab vedotin, Rituximab, Lenalidomide, Placebo

Seagen, a wholly owned subsidiary of Pfizer

Diffuse Large B-cell Lymphoma

11/25

CRESCENDO, NCT06072131: To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

Recruiting

504

Europe, Canada, US, RoW

Acrotech Biopharma Inc.

Peripheral T Cell Lymphoma

07/30

11/30

NCT04442022 / 2020-000605-84: A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) with or Without Selinexor in Patients with Relapsed/Refractory Diffuse Large B-cell Lymphoma

Recruiting

2/3

501

Europe, US, RoW

Karyopharm Therapeutics Inc

Relapsed/refractory Diffuse Large B-cell Lymphoma

12/25

SGN35-032, NCT04569032 / 2020-002336-74: A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Active, not recruiting

Europe, US, RoW

brentuximab vedotin, ADCETRIS, cyclophosphamide, doxorubicin, prednisone

Seagen, a wholly owned subsidiary of Pfizer

Peripheral T-cell Lymphoma

05/24

12/25

RESILIENCE, NCT05223413: REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs

Recruiting

N/A

608

Europe

RIPC, Simulated RIPC (Sham)

Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III, European Commission

Anthracycline-induced Cardiac Toxicity, Lymphoma

06/26

12/26

Feliu, Jaime

ASPIRE, NCT05254171: Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

Recruiting

2/3

600

Europe, US, RoW

SBP-101, ivospemin, Nab-paclitaxel, Abraxane, Gemcitabine, Gemzar, Placebo

Panbela Therapeutics, Inc.

Pancreatic Cancer Metastatic, Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Stage IV

08/26

01/27

IMC-C103C-101, NCT03973333: Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab

Withdrawn

1/2

Europe, US

IMC-C103C, Atezolizumab, TECENTRIQ

Immunocore Ltd

Select Advanced Solid Tumors

09/23

PAUF, NCT05141149 / 2021-000682-32: First in Human Phase1/2a Clinical Trial of Anti- Monoclonal Antibody PBP1510 in Patients With Pancreatic Cancer

Recruiting

1/2

Europe, US, RoW

PBP1510 (400mg/16mL), Gemcitabine (1000 mg/m^2)

Prestige Biopharma Limited, Prestige Biopharma Limited

Pancreatic Cancer

02/26

12/26

CHEMOFAST, NCT04247464: Short-term Fasting as an Enhancer of Chemotherapy: Pilot Clinical Study on Colorectal Carcinoma Patients

Completed

N/A

Europe

Fasting

IMDEA Food, Hospital Infanta Sofia, Hospital Universitario La Paz

Fasting

02/23

Espinosa, Enrique

EBIN, NCT03235245 / 2017-002887-42: Immunotherapy With Ipilimumab and Nivolumab Preceded or Not by a Targeted Therapy With Encorafenib and Binimetinib

Active, not recruiting

271

Europe

Nivolumab + Ipilimumab, Encorafenib + Binimetinib

European Organisation for Research and Treatment of Cancer - EORTC

Unresectable Stage III Melanoma, Stage IV Melanoma

10/23

01/27

OCULE-01, NCT06717126: A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal Melanoma

Recruiting

Europe

roginolisib, IOA-244, Investigator choice of standard therapy

iOnctura

Uveal Melanoma, Ocular Melanoma

12/27

12/28

Gomez, Carmen

EXO, NCT05563402: "Evaluation of Usability and Safety of the Self-balancing Walking System Atalante in Patients With Multiple Sclerosis"

Completed

N/A

Europe

Atalante

Multiple Sclerosis Center of Catalonia

Multiple Sclerosis, Ataxia, Paraplegia

12/22

03/23

NCT06615947: Conventional Multidisciplinary Gait Rehabilitation VR Robotic Self-balancing Based Gait Rehabilitation

Enrolling by invitation

N/A

Europe

Robotic gait training, Robotic, Atalante Gait Training, tRHB, Physical therapy, gait training

Multiple Sclerosis Center of Catalonia

Multiple Sclerosis, Gait Disorders, Neurologic

03/25

Sanchez, Andres F

innovaTV 301, NCT04697628 / 2019-001655-39: Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

Active, not recruiting

502

Europe, Canada, Japan, US, RoW

tisotumab vedotin, TIVDAK, PF-08046057, topotecan, vinorelbine, gemcitabine, irinotecan, pemetrexed

Seagen, a wholly owned subsidiary of Pfizer, Genmab

Cervical Cancer

07/23

05/26

ABX464-106, NCT05507216: ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2

Recruiting

612

Europe, Canada, Japan, US, RoW

ABX464, Obefazimod, Placebo

Abivax S.A.

Ulcerative Colitis

03/25

04/25

ABTECT, NCT05535946: - Maintenance

Recruiting

1050

Europe, Canada, Japan, US, RoW

ABX464, Obefazimod, Placebo

Abivax S.A.

Ulcerative Colitis

01/26

01/30

CAMPFIRE, NCT05999994: A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Recruiting

105

Europe, Japan, US, RoW

Ramucirumab, LY3009806, Cyclophosphamide, Vinorelbine, Gemcitabine, LY188011, Docetaxel, Abemaciclib, LY2835219, Irinotecan, Temozolomide

Eli Lilly and Company

Neoplasms, Child, Adolescent

05/27

NCT05440786 / 2021-004734-11: CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Active, not recruiting

Europe, Japan, US, RoW

Abemaciclib, LY2835219, Irinotecan, Temozolomide

Eli Lilly and Company

Sarcoma, Ewing, Neoplasm Metastasis

01/25

09/28

STRO-002-GM1, NCT03748186: Study of STRO-002, an Anti-Folate Receptor Alpha (FolRα) Antibody Drug Conjugate in Ovarian & Endometrial Cancers

Completed

136

Europe, US

STRO-002

Sutro Biopharma, Inc.

Ovarian Cancer, Ovarian Carcinoma, Ovary Cancer, Endometrial Cancer, Endometrioid Adenocarcinoma, Fallopian Tube Cancer, Primary Peritoneal Carcinoma

06/24

Ruiz, Elena SÃ¡ez

IMPRICA, NCT03803280: Implementation of Enhanced Recovery Protocol in Spain

Recruiting

N/A

2000

Europe

ERAS program

Grupo Español de Rehabilitación Multimodal, Instituto de Investigación Sanitaria Aragón, Instituto Aragones de Ciencias de la Salud

Major Surgery

07/22

12/22

LESAS, NCT04305314: Long-term Enlarged Survival After an Enhanced Recovery Protocol ().

Recruiting

N/A

750

Europe

PRI (Enhanced Recovery after surgery protocol)

Grupo Español de Rehabilitación Multimodal, Instituto de Salud Carlos III, Instituto de Investigación Sanitaria Aragón

Major Surgery

09/22

09/25

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

FLOE, NCT06047132: PREDICTIVE ABILITY OF A PANEL OF BIOMARKERS IN SALIVA IN HEALTHY AND PERIODONTALLY AFFECTED SUBJECTS

Active, not recruiting

N/A

100

Europe

Salivaru biomarkers

Universidad Complutense de Madrid

Periodontitis, Saliva, Biomarkers

06/24

01/25

LeakyBraInCS, NCT05950009: Relationship Between Major Depression and Periodontal Diseases

Recruiting

N/A

122

Europe

No intervention (observational studies)

Universidad Complutense de Madrid, Ministerio de Economía y Competitividad, Spain

Major Depressive Disorder, Periodontitis

01/26

03/26

LeakBrainRCT, NCT06036472: Impact of Periodontal Therapy on Mental Health Parameters

Recruiting

N/A

Europe

Standard periodontal therapy (steps 1 & 2), supragingival debridement with anesthesia (step 1)

Universidad Complutense de Madrid, Ministerio de Economía y Competitividad, Spain

Periodontitis, Depression

01/26

Alonso, Marta

NCT06214052: VH4524184 Proof-of-Concept in Treatment-Naïve Adults Living With HIV-1

Completed

Europe, Canada, US, RoW

VH4524184, Placebo

ViiV Healthcare, GlaxoSmithKline

HIV Infections

06/24

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Borobia, Alberto

VORIGENPHARM, NCT04238884: Effectiveness and Efficiency of a Voriconazole Preemptive Genotyping Strategy

Recruiting

146

Europe

Voriconazole preemptive genotyping strategy, Voriconazole clinical practice

Instituto de Investigación Hospital Universitario La Paz

Invasive Fungal Infections

01/20

12/22

DermAtOmics, NCT05692843: Optimization of Cyclosporin in Atopic Dermatitis Through Multiomic Predictive Models of Treatment Response

Recruiting

100

Europe

Cyclosporin A, Prospective, Follow-up of Cyclospoin treatment already started, Ambispective

Instituto de Investigación Hospital Universitario La Paz

Atopic Dermatitis

11/23

07/24

Gutierrez, Juan

POTHeR, NCT06911736: Effect of the Postoperative Trendelenburg Position on Chronic Subdural Hematoma Recurrence

Recruiting

N/A

254

RoW

Trendelenburg position

Universidad de Antioquia

Chronic Subdural Hematoma, Trendelenburg, Recurrence, Mortality, Prognosis, Clinical Trials

02/25

04/27

Bravo, Maria Fe

AGES-Mind, NCT03309475: Effectiveness of a Mindfulness-based Group Training Addressing Social Cognition in First Episode Psychosis

Completed

N/A

Europe

Instituto de Investigación Hospital Universitario La Paz, Carlos III Health Institute, European Regional Development Fund

Schizophrenia and Disorders With Psychotic Features, Psychotic Episode

01/23

Munoz, Ainoa

AGES-Mind, NCT03309475: Effectiveness of a Mindfulness-based Group Training Addressing Social Cognition in First Episode Psychosis

Completed

N/A

Europe

Instituto de Investigación Hospital Universitario La Paz, Carlos III Health Institute, European Regional Development Fund

Schizophrenia and Disorders With Psychotic Features, Psychotic Episode

01/23

Gimeno, Blanca Fuentes

AMASCIS-02, NCT04280003: Allogeneic Adipose Tissue-derived Mesenchymal Stem Cells in Ischemic Stroke

Recruiting

Europe

Alogenic adipose tissue-derived stem cells, Placebo solution

Instituto de Investigación Hospital Universitario La Paz

Ischemic Stroke, Adipose Tissue-derived Stem Cell, Functional Status

07/23

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Tension, NCT03094715: Efficacy and Safety of Thrombectomy in Stroke With Extended Lesion and Extended Time Window

Terminated

N/A

253

Europe, Canada, RoW

Thrombectomy, Mechanical thrombectomy, Best medical care, Control group

Stroke, Acute, Cerebral Stroke, Cerebrovascular Stroke, Apoplexy; Brain

05/23

11/23

NCT05871502: Glycemia and Ischemia Reperfusion Brain Injury in Patients With Acute Cerebral Infarction Treated With Mechanical Thrombectomy

Recruiting

N/A

100

Europe

Subcutaneous blood glucose monitoring device

Instituto de Investigación Hospital Universitario La Paz

Cerebral Infarction

04/25

GÃ³mez, Lydia de la Fuente

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Iborra, Cristian Sempere

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

LeciÃ±ana, MarÃa Alonso de

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Yvorra, Silvia Pastor

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Bobillo, Ricardo Riguel

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

ARIES, NCT05486221: Atrial Imaging and Cardiac Rhythm In Embolic Stroke

Recruiting

N/A

150

Europe

Extensive cardiologic work-up

Instituto de Investigación Hospital Universitario La Paz, Hospital Universitario La Paz, Proyecto Ictus- Grupo Estudio Enfermedades CerebroVasculares de la Sociedad Española de Neurología

Cryptogenic Stroke, Atrial Fibrillation, Atrial Dilatation, Stroke, Ischemic

12/22

KOALA-IS, NCT05486351: Keeping Oral o Parental AnticoaguLation in the Acute Phase of Cardioembolic Ischemic Stroke

Recruiting

N/A

318

Europe

Observation

Instituto de Investigación Hospital Universitario La Paz, Hospital Universitario La Paz, Daiichi Sankyo, Inc., Fundación Freno al ICTUS

Cardioembolic Stroke, Anticoagulant Therapy, Stroke Recurrence, Haemorrhagic Transformation Stroke

12/23

Ares, Gerardo Ruiz

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Pardo, Jorge RodrÃguez

NCT05357989 / 2022-001542-38: A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD

Completed

523

Europe, US

buntanetap/posiphen, Posiphen Tartrate, ANVS401, Placebo

Annovis Bio Inc., TFS Trial Form Support

Parkinson's Disease, Idiopathic

12/23

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Bueno, Nereida

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Blanco, Paloma

NCT04289493: DUbbing Language-therapy CINEma-based in Aphasia Post-Stroke

Completed

N/A

Europe

Language and functional communication therapy

Instituto de Investigación Hospital Universitario La Paz, Universidad Pontificia Comillas, Asociación Afasia Activa, La Caixa Foundation

Aphasia, Post-Ictal

09/24

Soria-Juan, Barbara

NCT04741321: Validation of VascuQol-6 Spanish Version

Recruiting

N/A

104

Europe

VascuQol-6 questionnaire Spanish version

Peripheral Artery Disease

02/21

Arcas, Mireia

NOMA, NCT04466007: Safety and Efficacy of Allogeneic Adipose Tissue Mesenchymal Stem Cells in Diabetic Patients With Critical Limb Ischemia

Completed

Europe

High dose allogeneic mesenchymal stromal cells, Low dose allogeneic mesenchymal stromal cells, Placebos

Limb Ischemia, Diabetic Foot

05/24

12/24

NCT06144567: Response to Upadacitinib of Enthesitis Evaluated by Ultrasound in Patients With Psoriatic Arthritis

Not yet recruiting

N/A

Europe

Upadacitinib, Rinvoq

Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz, Hospital Universitario de Móstoles

Psoriatic Arthritis

06/26

Jurado, Alfonso

RollerCoaster, NCT04181268 / 2011-002445-36: ROtational Atherectomy, Lithotripsy or LasER for the Treatment of CAlcified STEnosis

Recruiting

N/A

150

Europe

Percutaneous coronary Intervention

Hospital Universitario La Paz

Coronary Artery Disease

11/23

ASSIST, NCT06939738: Artificial Intelligence Scalable Solution for ST Myocardial Infarction

Recruiting

N/A

500

Europe

Idoven 1903 S.L.

Acute Myocardial Infarction (AMI)

11/25

Galeote, Guillermo

CRATER, NCT05353946: Coronary Rotational Atherectomy Elective vs. Bailout in Severely Calcified Lesions and Chronic Renal Failure

Recruiting

N/A

124

Europe

Percutaneous coronary intervention (PCI)

Guillermo Galeote; MD, PhD

Coronary Artery Disease, Chronic Renal Failure

12/22

12/23

Gonzalez, Patricio

TREX, NCT03089905: A Study to Compare the Long-term Outcomes After Two Different Anaesthetics

Active, not recruiting

450

Europe, US, RoW

Sevoflurane, Sevorane, Remifentanil, Ultiva, Dexmedetomidine, Precedex, Dexmedetomidine Ever Pharma

Anesthesia, Neurotoxicity, Child Development

03/26

06/26

Mannucci, Alessandro

AACRC, NCT06342440: Early Detection of Advanced Adenomas and Colorectal Cancer

Recruiting

N/A

2000

Europe, Japan, US, RoW

DENEB, DENEB (DEtection of colorectal NEoplasias in Blood)

City of Hope Medical Center

12/25

T1CR, NCT06314971: Predicting Local and Distant Recurrence in T1 Colorectal Cancer

Recruiting

N/A

200

Europe, Japan, US

Tw1CE, T1 Colorectal cancer rEcurrence (Tw1CE)

City of Hope Medical Center

Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I, Colorectal Neoplasms Malignant, Colorectal Cancer Recurrent

06/26

CENSURE, NCT06314958: Stage II/III Colorectal Cancer Recurrence

Recruiting

N/A

400

Europe, US, RoW

CENSURE, CENSURE (CpG mEthylation-based epigeNetic SignatURE)

City of Hope Medical Center

Colorectal Cancer, Colorectal Adenocarcinoma, Colorectal Cancer Stage II, Colorectal Cancer Stage III, Colorectal Cancer Recurrent

06/25

PCDC, NCT06388967: Pancreatic Cancer Detection Consortium

Recruiting

N/A

2000

Japan, US, RoW

PANcreatic cancer Exosome Early detectiON (PANXEON), PANXEON (PANcreatic cancer Exosome Early detectiON)

City of Hope Medical Center

11/25

ENCODE, NCT06342401: Early Onset Colorectal Cancer Detection

Recruiting

N/A

400

Europe, Japan, US

ENCODE, ENCODE (Early oNset COlorectal cancer DEtection)

City of Hope Medical Center

10/25

ENCORE, NCT06271980: Early-Onset Colorectal Cancer Recurrence

Completed

N/A

177

ENCORE, ENCORE (Early oNset COlorectal cancer REcurrence)

City of Hope Medical Center, IRCCS San Raffaele Hospital, Milan, Italy, Institute of Biomedical Research of Salamanca, Salamanca, Spain

Colorectal Cancer Recurrent, Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I, Colorectal Cancer Stage II, Colorectal Cancer Stage III

02/24

EMERALD, NCT06381583: A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal Adenocarcinoma

Completed

N/A

658

EMERALD (Esophageal MicroRNAs for BaRRett's esophagus, Adenocarcinoma, and Dysplasia)

City of Hope Medical Center

04/24

LYNX-EYE, NCT06708429: Lynch Syndrome X-Talk of Enteral Mucosa With Immune System

Recruiting

N/A

300

Europe, US

LYNX EYE (Lynch syndrome X-Talk of Enteral mucosa with Immune System)

San Raffaele University

06/33

06/34

DEMETRA, NCT05732623: Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

Recruiting

N/A

2300

Europe, US

Semi Quantitative Food Frequency Questionnaire (SQFFQ)

Colorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk Reduction

01/30

01/35

Borobia-Perez, Alberto M

NCT05965414: Safety and Pharmacokinetics of Single Ascending Doses and Multiple Ascending Doses of CS6253 in Healthy Volunteers

Completed

Europe

CS6253 Solution for Injection, Placebo

Artery Therapeutics, Inc., National Institute on Aging (NIA)

Alzheimer's Disease

07/24

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