| yang, li |
NCT04376528: Mycophenolate Mofetil Versus Cyclosporin A in the Treatment of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome Due to Nonresponse to Standard Therapy |
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| Recruiting | 4 | 89 | RoW | Cyclosporin A, Mycophenolate Mofetil | West China Hospital | Hepatitis, Autoimmune, Primary Biliary Cholangitis, Immunosuppression | 12/21 | 12/21 | | |
NCT04617561: Ursodeoxycholic Acid Combined With Low Dose Glucocorticoid in the Treatment of PBC With AIH Features II |
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| Recruiting | 4 | 90 | RoW | Ursodeoxycholic acid, UDCA;Ursofalk(250mg*25,Losan Pharma GmbH), Ursodeoxycholic acid+Low Dose Glucocorticoid(Methylprednisolone), Medrol（4mg*30,pfizer ltalia srl) | West China Hospital | Hepatitis, Autoimmune, Primary Biliary Cholangitis | 11/22 | 11/22 | | |
NCT04618575: Ursodeoxycholic Acid Combined With Total Glucosides of Paeony in the Treatment of PBC With AIH Features 1 |
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| Recruiting | 4 | 137 | RoW | Ursodeoxycholic acid combined with total glucosides of paeony, Ursodeoxycholic acid only | West China Hospital | Hepatitis, Primary Biliary Cholangitis, Autoimmune | 11/22 | 11/22 | | |
NCT04553003: Glucocorticosteroid Therapy on Drug-induced Liver Injury: a Prospective Non-randomized Concurrent Control Trial |
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| Recruiting | 4 | 80 | RoW | Glucocorticoids+hepatoprotectant, prednisone, methylprednisolone, hepatoprotectant, Ademetionine1,4-Butanedisulfonate, Polyene Phosphatidyl choline | Li Yang | Drug-induced Liver Injury | 04/25 | 04/25 | | |
NCT05463965: A Study to Evaluate the Efficacy and Safety of QM1114-DP for the Treatment of Moderate to Severe Glabellar Lines |
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| Completed | 3 | 605 | RoW | QM1114-DP, OnabotulinumtoxinA, Placebo | Galderma R&D | Moderate to Severe Glabellar Lines | 01/23 | 06/23 | | |
NCT06775860: ICP-332 in Subjects with Moderate to Severe Atopic Dermatitis |
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| Recruiting | 3 | 552 | RoW | ICP-332 Tablets, ICP-332 Placebo Tablets | Beijing InnoCare Pharma Tech Co., Ltd. | Atopic Dermatitis | 11/26 | 12/26 | | |
METIS, NCT02831959: Pivotal, Open-label, Randomized Study of Radiosurgery with or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases from Non-small Cell Lung Cancer (NSCLC). |
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| Completed | 3 | 298 | Europe, Canada, US, RoW | NovoTTF-200M device, Best Standard of Care | NovoCure GmbH | Brain Metastases from Non-small Cell Lung Cancer (NSCLC) | 11/24 | 11/24 | | |
| Active, not recruiting | 2/3 | 350 | Europe, Japan, US, RoW | Abemaciclib, LY2835219, Abiraterone Acetate, Prednisone, Placebo | Eli Lilly and Company | Prostate Cancer | 01/24 | 06/26 | | |
NCT06413654: A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD) |
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| Recruiting | 2/3 | 132 | RoW | B001, Placebo | Shanghai Jiaolian Drug Research and Development Co., Ltd, Shanghai Pharmaceuticals Holding Co., Ltd | Neuromyelitis Optica Spectrum Disorders | 10/27 | 02/29 | | |
NCT04492293: An Efficacy and Safety Study of ICP-192 in Subjects With Bladder Urothelial Cancer |
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| Recruiting | 2 | 115 | RoW | ICP-192 | Beijing InnoCare Pharma Tech Co., Ltd. | Bladder Urothelial Cancer | 12/24 | 06/25 | | |
NCT02874586: Plasma Exchange Combination of Immunosuppressive Regimens for Auto-immune Hepatitis |
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| Recruiting | N/A | 20 | RoW | Plasma exchange combination of immunosuppressive regimens | Xiaoli Fan | Hepatitis, Autoimmune | 04/21 | 09/21 | | |
NCT02994537: Study of the Clinical Features of Autoimmune Hepatitis |
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| Recruiting | N/A | 500 | RoW | Different biochemical results or pathogenesis. | Li Yang, West China Hospital | Hepatitis, Autoimmune | 06/22 | 12/22 | | |
NCT02936596: Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome |
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| Recruiting | N/A | 53 | RoW | Ursodeoxycholic acid combination of immunosuppressive agents, Ursodeoxycholic Acid | Xiaoli Fan | Hepatitis, Autoimmune, Cholangitis, Liver Cirrhosis, Biliary, Cholestasis | 06/22 | 06/22 | | |
| Recruiting | N/A | 910 | RoW | second forward view | Zhu Xiaojia | Adenoma Detection Rate | 06/22 | 06/22 | | |
NCT06597838: Development and Validation of a Real-time Prediction Model for Acute Kidney Injury in Hospitalized Patients |
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| Recruiting | N/A | 161876 | RoW | | Peking University First Hospital | Prediction Model | 10/24 | 12/24 | | |
NCT06417736: Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age Women |
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| Recruiting | N/A | 75 | RoW | Megestrol Acetate 40 MG, membrane-inhibiting formula | Women's Hospital School Of Medicine Zhejiang University | Endometrial Cancer Stage I, Endometrial Hyperplasia | 07/25 | 12/26 | | |
NCT05152446: Implementation of an Infusion Management Scheme to Improve Patient Outcome in Tertiary Children's Hospitals |
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| Terminated | N/A | 1000 | RoW | Infusion management scheme | Children's Hospital of Fudan University, Xiamen Children's Hospital, Anhui Provincial Children's Hospital, Dalian women and children's medical group, First Affiliated Hospital of Guangxi Medical University, Qidong Women's and Children's Health, Chengdu Women's and Children's Central Hospital, Hunan Children's Hospital, Tongji Hospital | Children,Hospitalized, Infusion, Infections | 11/24 | 11/24 | | |
NCT06076057: Vital Signs Monitoring of Emergency Responders in Different States |
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| Recruiting | N/A | 135 | RoW | vital signs monitoring | Qilu Hospital of Shandong University | Heart Rate Monitoring | 12/23 | 02/24 | | |
NCT06606522: A Clinical Diagnostic System for Intrinsic Acute Kidney Disease |
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| Completed | N/A | 1360 | RoW | Clinical model, Urinary biomarkers | Peking University First Hospital, Affiliated Hospital of Hebei University, Beijing Miyun Hospital, Dongzhimen Hospital, Beijing University of Chinese Medicine, Taiyuan Central Hospital of Shanxi Medical University | Acute Kidney Disease | 06/24 | 09/24 | | |
NCT06384300: Financial Incentives and Motivational Intervention to Improve Gastric Cancer Screening in China |
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| Not yet recruiting | N/A | 5000 | NA | Financial Incentives, Motivational Intervention, Mixed Intervention | Peking University | Gastric Cancer | 01/27 | 07/27 | | |
NCT03933891: Magnetic Resonance Technics for the Assessment of Liver Function Before and After TIPS |
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| Recruiting | N/A | 200 | RoW | TIPS | West China Hospital | Liver Cirrhosis, Transjugular Intrahepatic Portosystemic Shunt (TIPS), Functional Magnetic Resonance Imaging | 08/24 | 05/25 | | |
| Recruiting | N/A | 420 | RoW | second examination of the proximal colon | Third People's Hospital of Jingdezhen City | Adenoma Miss Rate | 12/24 | 12/24 | | |
NCT06123858: Non-alcoholic Steatohepatitis Registry Platform Study |
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| Recruiting | N/A | 2500 | RoW | | AstraZeneca | NASH With Fibrosis | 12/26 | 12/26 | | |
| Peng, Xingchen |
NCT04414566: Induction Chemotherapy Plus Radiotherapy Alone in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma |
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| Not yet recruiting | 3 | 562 | RoW | gemcitabine and cisplatin; docetaxel, cisplatin and fluorouracil, GP;TPF, IMRT, IMRT and concurrent cisplatin | West China Hospital | Nasopharyngeal Carcinoma | 05/22 | 05/25 | | |
| Active, not recruiting | 3 | 291 | Europe, Canada, Japan, US, RoW | Selpercatinib, LY3527723, LOXO-292, Cabozantinib, Vandetanib | Loxo Oncology, Inc., Eli Lilly and Company | Medullary Thyroid Cancer | 05/23 | 02/26 | | |
NCT05805800: Olanzapine and 5-HT3 With or Without Dexamethasone to Prevent CINV |
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| Recruiting | 3 | 238 | RoW | 5HT3RA+Olanzapine, 5HT3RA+Olanzapine+Dexamethasone | Xingchen Peng | Chemotherapy-induced Nausea and Vomiting | 03/24 | 03/25 | | |
NCT06663956: A Randomized Controlled Trial of a Web-based Platform for Cancer Pain Management |
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| Recruiting | 3 | 100 | RoW | a patient self-reporting applet | West China Hospital | Cancer Pain | 10/26 | 10/26 | | |
NCT04316039: Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After Surgery |
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| Recruiting | 2/3 | 250 | RoW | Temozolomide, intensity modulated radiation therapy | West China Hospital | Low-grade Glioma | 04/23 | 12/28 | | |
| Completed | 2 | 160 | RoW | Streptococcus salivarius K12, OralBiotic BLIS K12 (NOW Foods, USA), Streptococcus salivarius K12 simulants | West China Hospital, Project funding | Head and Neck Squamous Cell Carcinoma | 11/22 | 11/22 | | |
NCT04318730: Phase II Study for Combination of Camrelizumab and Apatinib in the Second-line Treatment of Recurrent or Metastatic Adrenocortical Carcinoma |
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| Recruiting | 2 | 21 | RoW | Camrelizumab, Apatinib | West China Hospital | Adrenocortical Carcinoma | 12/23 | 04/25 | | |
| Recruiting | 2 | 28 | RoW | Nab-paclitaxel, Albumin-bound paclitaxel, Abraxane, Cisplatin, CDDP, Tislelizumab, BGB-A317, Afatinib | West China Hospital | Head and Neck Squamous Cell Carcinoma | 08/23 | 08/24 | | |
| Recruiting | 2 | 23 | RoW | Tislelizumab, BGB-A317, Afatinib | West China Hospital | Head and Neck Cancer | 08/23 | 08/24 | | |
NCT05659186: PD-1 Inhibitor and Anlotinib Combined With Multimodal Radiotherapy in Recurrent or Metastatic Anaplastic Thyroid Cancer |
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| Recruiting | 2 | 20 | RoW | Tislelizumab, BGB-A317, Anlotinib, AL3818, Radiotherapy | West China Hospital | Thyroid Cancer | 12/24 | 12/25 | | |
NCT06804850: A Randomized Controlled Study Comparing Low-dose Radiotherapy Combined With Target-free Therapy Versus Target-free Therapy Alone in Neoadjuvant Treatment for Resectable Head and Neck Squamous Cell Carcinoma. |
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| Not yet recruiting | 2 | 98 | RoW | Tislelizumab, Immunotherapy, Afatinib, Targeted therapy, Low dose radiotherapy, Radiotherapy | West China Hospital | Head and Neck Cancer | 06/26 | 06/26 | | |
NCT05299203: BH4 in the Prevention and Treatment of Radiation-induced Skin Reactions for Head and Neck Squamous Cell Carcinoma (Including Nasopharyngeal Carcinoma) |
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| Not yet recruiting | 1a/1b | 18 | NA | Sapropterin dihydrochloride tablets | West China Hospital | Head and Neck Squamous Cell Carcinoma | 12/22 | 05/23 | | |
NCT05714748: Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors |
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| Recruiting | 1 | 9 | RoW | EBV mRNA vaccine | West China Hospital | Malignant Tumors | 01/24 | 01/25 | | |
NCT05707910: Clinical Study of Therapeutic Immunological Agent for EBV-positive Advanced Malignant Tumors |
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| Recruiting | 1 | 9 | RoW | EBV immunological agent, Toripalimab 240mg | West China Hospital | Malignant Tumor | 01/24 | 01/25 | | |
NCT05738447: Application of mRNA Immunotherapy Technology in Hepatitis B Virus-related Refractory Hepatocellular Carcinoma |
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| Recruiting | 1 | 9 | RoW | HBV mRNA vaccine | West China Hospital | Liver Cancer, Hepatocellular Carcinoma | 01/24 | 01/25 | | |
NCT06332664: Early Nutrition Intervention for M1 Stage Cancer Patients |
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| Recruiting | 1 | 194 | RoW | Early Nutrition Intervention | Xingchen Peng | Nutrition, Cancer Metastatic | 01/25 | 07/25 | | |
NCT06494189: Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma |
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| Recruiting | 1 | 29 | RoW | Tislelizumab, Afatinib, Low dose radiotherapy | West China Hospital | Head and Neck Cancer | 07/25 | 12/25 | | |
NCT06519552: A Clinical Study Evaluating the Safety, Tolerability, and Initial Efficacy of JWK008 in Patients With Mucopolysaccharidosis Type I |
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| Recruiting | 1 | 6 | RoW | JWK008 Single intravenous infusion administration | West China Hospital | Mucopolysaccharidosis Type I | 06/26 | 06/29 | | |
NCT06666153: Clinical Study of Therapeutic Immunological Agent for EBV Lymphoproliferative Diseases |
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| Not yet recruiting | 1 | 27 | RoW | EBV immunological agent | West China Hospital | CAEBV (Chronic Active Epstein-Barr Virus Infection) Syndrome, PTLDs | 12/25 | 12/26 | | |
NCT06080984: The Application of Novel Oncolytic Virus in Late Stage Solid Tumors |
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| Recruiting | 1 | 24 | RoW | Oncolytic Virus SDJ001, Oncolytic Virus YD06-1 | West China Hospital | Malignant Tumor | 10/24 | 10/25 | | |
NCT06741982: A Clinical Study on Neoadjuvant Treatment of Resectable Head and Neck Squamous Carcinoma With Immune-targeted Therapy and Lysogenic HSV Virus |
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| Recruiting | 1 | 21 | RoW | Lysogenic HSV virus., Biological agent, Tislelizumab, Immunotherapy, Afatinib, Targeted therapy | West China Hospital | HNSCC, Lysogenic HSV Virus, Neoadjuvant Therapy, Immunotherapy, Targeted Therapy | 12/26 | 12/26 | | |
NCT06114056: A Clinical Study Evaluating the Safety, Tolerability, and Initial Efficacy of Single Intravenous Infusion of JWK007 in Patients With Duchenne Muscular Dystrophy (DMD) |
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| Recruiting | 1 | 6 | RoW | JWK007 Single intravenous infusion administration | West China Hospital | Duchenne Muscular Dystrophy | 06/25 | 12/28 | | |
NCT06272617: Acupuncture for Prevention and Treatment of Oral-related Complications Caused by Radiotherapy for Head and Neck Cancer |
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| Recruiting | N/A | 138 | RoW | verum acupuncture, sham acupuncture | West China Hospital, West China Fourth Hospital, Sichuan University | Malignant Tumor of Head and/or Neck, Radiotherapy; Complications | 07/24 | 07/25 | | |
NCT05828004: Effect of Whole-Course Multidisciplinary Care Intervention on Patients With Head and Neck Carcinoma |
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| Completed | N/A | 226 | RoW | Whole-Course Multidisciplinary Care Intervention | West China Hospital | Head and Neck Carcinoma | 10/23 | 12/23 | | |
NCT06390176: Lactobacillus Rhamnosus GG Alleviates Oral Mucositis in Patients Undergoing Radiotherapy |
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| Recruiting | N/A | 132 | RoW | Lactobacillus rhamnosus GG powder, Placebo-containing tablets, Radiotherapy | West China Hospital | Oral Mucositis | 03/25 | 03/25 | | |
NCT06285591: Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors |
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| Recruiting | N/A | 160 | RoW | Lactobacillus Reuteri Tablets, Placebo-containing tablets, Radiotherapy | West China Hospital, The General Hospital of Western Theater Command | Oral Mucositis (Ulcerative) Due to Radiation | 12/24 | 12/24 | | |
NCT06484166: Efficacy of Fullerene in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer . |
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| Not yet recruiting | N/A | 132 | NA | Fullerene cream, Trolamine (Biafine) | West China Hospital | Radiation Dermatitis | 12/24 | 04/25 | | |
NCT06690346: Systematic Oral Education for Prevention of Oral-related Complications Caused by Radiotherapy for Head and Neck Cancer |
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| Recruiting | N/A | 150 | RoW | Systematic oral health education, Routine oral health education | West China Hospital, West China Fourth Hospital, Sichuan University | Malignant Tumor of Head And/or Neck, Radiotherapy; Complications | 08/25 | 08/26 | | |
NCT06674499: Development and Evaluation of a Self-Management Model for Cancer Rehabilitation |
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| Recruiting | N/A | 144 | RoW | Self-help rehabilitation model, Conventional rehabilitation model | Xingchen Peng | Head and Neck Cancer, Rehabilitation, Psychotherapy | 12/26 | 06/27 | | |
