Academic Unit of Neurology, Trinity College Dublin, The University of Dublin
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 3 Trials 
7 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Hardiman, Orla
COURAGE-ALS, NCT04944784 / 2020-004040-29: A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)

Terminated
3
486
Europe, Canada, US, RoW
Reldesemtiv, Placebo
Cytokinetics
Amyotrophic Lateral Sclerosis
07/23
07/23
COURAGE OLE, NCT05442775 / 2021-004727-33: A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031)

Terminated
3
71
Europe, Canada, US, RoW
Reldesemtiv
Cytokinetics, Cytokinetics Inc
Amyotrophic Lateral Sclerosis
06/23
06/23
LIGHTHOUSE II, NCT05193994: Triumeq in Amyotrophic Lateral Sclerosis

Active, not recruiting
3
390
Europe, RoW
Dolutegravir, Abacavir and Lamivudine, Triumeq, Placebo
Macquarie University, Australia, King's College London, Stichting TRICALS Foundation
Amyotrophic Lateral Sclerosis
08/26
08/26
NCT05633459: A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

Recruiting
1
64
Europe, Canada
Multiple ascending doses of QRL-201, Multiple ascending doses of Placebo, QRL-201, Placebo
QurAlis Corporation
Amyotrophic Lateral Sclerosis
08/26
08/26
NCT06320444: Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Recruiting
N/A
240
Europe
232 Electrode Electrophysiology (EEG-ECG-EMG-EXG), Peripheral Nerve Stimulation, Vibration Induced Stimulation
University of Dublin, Trinity College, Motor Neurone Disease Association, UK, Irish Research Council, IE, Health Research Board, IE, Research Motor Neurone, IE, Thierry Latran Foundation, FR, ALS Association, USA
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, Motor Neuron Disease Progressive Spinal Muscle Atrophy, Primary Lateral Sclerosis, Multiple Sclerosis, Postpoliomyelitis Syndrome
12/24
07/25
NCT04918251: EEG and TMS-based Biomarkers of ALS, MS and FTD

Recruiting
N/A
400
Europe
128 electrode electroencephalography (EEG), Transcranial magnetic stimulation (TMS)
University of Dublin, Trinity College, Motor Neurone Disease Association, UK, Irish Research Council, IE, Health Research Board, IE, Research Motor Neurone, IE, Thierry Latran Foundation, FR, ALS Association, USA
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Multiple Sclerosis
02/23
04/23
MotorMarker, NCT05663008: Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis

Recruiting
N/A
400
Europe
128 electrode electroencephalography (EEG), Bipolar surface electromyography (sEMG), High-density electromyography (HD-EMG)
University of Dublin, Trinity College, Motor Neurone Disease Association, UK, Irish Research Council, IE, Research Motor Neuron, IE, Thierry Latran Foundation, FR, ALS Association, USA
ALS (Amyotrophic Lateral Sclerosis), Postpoliomyelitis Syndrome, Spinal Muscular Atrophy
01/27
09/27

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