| Singer, Mervyn |
NUC-CAP, NCT05647096: Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating CfDNA/NETs in Subjects with Sepsis |
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| Not yet recruiting | N/A | 73 | Europe | NucleoCapture device | Santersus AG, ISS AG | Sepsis, Respiratory Failure | 05/27 | 05/27 | | |
| Forster, Martin D |
COSTAR Lung, NCT04655976 / 2020-003433-37: Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy |
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| Active, not recruiting | 3 | 758 | Europe, Canada, Japan, US, RoW | Cobolimab, Dostarlimab, Docetaxel | GlaxoSmithKline | Lung Cancer, Non-Small Cell | 04/25 | 10/25 | | |
| Active, not recruiting | 2 | 130 | Europe | Avelumab, Cetuximab | University College, London, Merck KGaA, Darmstadt, Germany | Head and Neck Cancer, Squamous Cell Carcinoma | 09/21 | 10/24 | | |
| Completed | 2 | 12 | Europe | Afatinib, Giotrif | University College, London, Boehringer Ingelheim | Non-small Cell Lung Cancer | 03/23 | 03/23 | | |
| Active, not recruiting | 2 | 171 | Europe, US, RoW | eftilagimod alpha, IMP321, efti, eftilagimod alfa, pembrolizumab (KEYTRUDA®), MK-3475 | Immutep S.A.S., Merck Sharp & Dohme LLC | HNSCC | 03/24 | 03/25 | | |
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| Active, not recruiting | 2 | 63 | Europe | Pembrolizumab, Keytruda | University College, London, Merck Sharp & Dohme LLC | Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma | 01/24 | 01/26 | | |
| Recruiting | 1/2 | 110 | Europe, US | CAR-GPC3 T Cells, BOXR1030 | Sotio Biotech Inc., SOTIO Biotech AG, SOTIO Biotech a.s. | Hepatocellular Carcinoma, Squamous Cell Carcinoma of the Lung, Merkel Cell Carcinoma, Myxoid/Round Cell Liposarcoma | 10/27 | 12/42 | | |
| Recruiting | 1/2 | 374 | Europe, Canada, Japan, US, RoW | Dazostinag, TAK-676, Pembrolizumab, Platinum, 5-fluorouracil | Takeda, Takeda Development Center Americas, Inc. (TDC Americas) | Solid Neoplasms | 01/26 | 01/26 | | |
| Recruiting | 1/2 | 265 | Europe, US, RoW | EP0031 | Ellipses Pharma | Advanced Solid Tumor | 12/26 | 06/27 | | |
| Recruiting | 1/2 | 170 | Europe | GTAEXS617 | Exscientia AI Limited, GT Apeiron LLC | Advanced Solid Tumor | 01/28 | 05/28 | | |
ORCA-2, NCT02308072: Phase I Study of Olaparib Combined With Cisplatin-based Chemoradiotherapy to Treat Locally Advanced Head and Neck Cancer |
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| Active, not recruiting | 1 | 70 | Europe | Olaparib, Cisplatin, IMRT | University College, London, Cancer Research UK, AstraZeneca | Head and Neck Cancer | 06/20 | 02/25 | | |
| Recruiting | 1 | 90 | Europe | NVG-111 | NovalGen Ltd. | Chronic Lymphocytic Leukaemia, Small Lymphocytic Lymphoma, Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B Cell Lymphoma, Non-small Cell Lung Cancer (NSCLC), Malignant Melanoma | 12/23 | 12/25 | | |
Patriot, NCT02223923: Phase I Study to Assess Safety of AZD6738 Alone and in Combination With Radiotherapy in Patients With Solid Tumours |
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| Active, not recruiting | 1 | 87 | Europe | AZD6738, Palliative radiotherapy | Royal Marsden NHS Foundation Trust, AstraZeneca, Cancer Research UK, RM/ICR Biomedical Research Centre | Solid Tumour Refractory to Conventional Treatment | 12/23 | 12/23 | | |
| Recruiting | 1 | 36 | Europe | OVM-200 | Oxford Vacmedix UK Ltd. | Prostate Cancer, Non Small Cell Lung Cancer, Ovarian Cancer | 11/25 | 01/26 | | |
| Recruiting | 1 | 275 | Europe, US | SGN-EGFRd2 | Seagen Inc. | Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Squamous Cell Carcinoma of the Head and Neck, Pancreatic Ductal Adenocarcinoma | 07/27 | 09/28 | | |
| Recruiting | 1 | 38 | Europe | Tepotinib, Pembrolizumab, MK-3475 | Institute of Cancer Research, United Kingdom, Merck Healthcare KGaA | Advanced Cancer, Non Small Cell Lung Cancer | 02/28 | 02/28 | | |
NCT06366438: A Trial of Two Universal Programs for Parents of Teenagers |
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| Completed | N/A | 1247 | Europe | ABC-teen, ParentWeb | Karolinska Institutet | Mental Health Issue, Mental Disorder, Adolescent Behavior, Adolescent Development, Parent-Child Relations, Parenting | 01/24 | 03/24 | | |
NCT04163367: A Randomized Controlled Study of Safer Kids: A Manualized Intervention to Prevent Child Abuse |
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| Active, not recruiting | N/A | 112 | Europe | Safer Kids, Intervention as usual (IAU) | Karolinska Institutet | Child Abuse, Child Maltreatment | 07/24 | 07/24 | | |
NCT06600139: Screening to Identify Parents in Need of Mental Health Support: a Feasibility Study in Child Welfare Services |
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| Not yet recruiting | N/A | 355 | NA | The Collaboration-Screening-Referral (SSH) model | Karolinska Institutet | Mental Disorder, Depression, Anxiety, Child Abuse, Child Neglect, Child Maltreatment | 09/25 | 09/25 | | |
NCT06572865: Identifying Parents in Child Welfare Services Who Need Mental Health Support: Depression and Anxiety Symptoms |
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| Not yet recruiting | N/A | 290 | NA | Screening for depression and anxiety | Karolinska Institutet | Mental Illness, Depression, Anxiety | 09/25 | 09/25 | | |
| Recruiting | N/A | 6000 | Europe | | The Christie NHS Foundation Trust | Cancer | 01/26 | 01/28 | | |
| Recruiting | N/A | 200 | Europe | | University College, London, Cancer Research UK | Head and Neck Cancer | 07/26 | 07/26 | | |
