UMC st Radboud
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 16 Trials 
20 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Herpen, CML van
DUCT, NCT05513365: Phase II Dutasteride in Combination With CAB vs CAB in SDC

Recruiting
2
26
Europe
Goserelin 10.8 mg, Zoladex, Bicalutamide 50 mg, Casodex, Dutasteride 0.5 mg, Avodart
Radboud University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development
Salivary Duct Carcinoma
09/25
09/27
DRUP, NCT02925234 / 2015-004398-33: The Drug Rediscovery Protocol ( Trial)

Recruiting
2
1550
Europe
Panitumumab, Vectibix, Olaparib, Lynparza, Dabrafenib, Tafinlar, Nilotinib, Tasigna, Trametinib, Mekinist, Erlotinib, Tarceva, Trastuzumab and Pertuzumab (combination treatment), Herceptin + Perjeta, Vemurafenib and Cobimetinib (combination treatment), Zelboraf + Cotellic, Vismodegib, Erivedge, Regorafenib, Stivarga, Nivolumab, Opdivo, Afatinib, Giotrif, Dabrafenib and trametinib, Tafinlar and Mekinist, Ribociclib, Kisqali, Lenvatinib, Lenvima, Pembrolizumab, Keytruda, Durvalumab, MEDI4736, Rucaparib, Rubraca, Axitinib, Inlyta, Palbociclib, Ibrance, Crizotinib, Xalkori, Sunitinib, Sutent, Cabozantinib, Cabometyx, Abemaciclib, Verzenios, Alectinib, Alecensa, Atezolizumab and Bevacizumab, Tecentriq and Avastin, Ipilimumab and nivolumab, Yervoy and Opdivo, Entrectinib, Rozlytrek, Talazoparib, Talzenna, Dacomitinib, Vizimpro, Lorlatinib, Lorviqua, Erdafitinib, Balversa, Alpelisib, Piqray, Niraparib, Zejula, Pemigatinib, Pemazyre, Selpercatinib, Retsevmo, Tepotinib, Tepmetko
The Netherlands Cancer Institute, Amgen, AstraZeneca, Bayer, Bristol-Myers Squibb, Novartis, Roche Pharma AG, Merck Sharp & Dohme LLC, Boehringer Ingelheim, Ipsen, Eisai Inc., Pfizer, Clovis Oncology - Pharma and, Eli Lilly and Company, Janssen, LP, GlaxoSmithKline, Incyte Corporation, Dutch Cancer Society, Stelvio for Life
Cancer, Tumors, Neoplasm, Neoplasia
09/27
12/27
Herpen, Carla van
LUPSA, NCT04291300: Lutetium-177-PSMA Radioligand Therapy in Advanced Salivary Gland Cancer Patients

Completed
2
12
Europe
Lutetium-177-PSMA-I&T, Lutetium-177 Prostate Specific Membrane Antigen
Radboud University Medical Center, Dutch Cancer Society
Salivary Gland Cancer, Salivary Duct Carcinoma, Adenoid Cystic Carcinoma
02/23
02/23
OpcemISA, NCT03669718 / 2018-000789-13: A Randomized Phase 2 Study of Cemiplimab ± ISA101b in HPV16-Positive OPC

Active, not recruiting
2
194
Europe, US, RoW
ISA101b, Cemiplimab, Placebo
ISA Pharmaceuticals, Regeneron Pharmaceuticals
Squamous Cell Carcinoma of the Oropharynx, HPV16 Positive
09/24
06/25
DUCT, NCT05513365: Phase II Dutasteride in Combination With CAB vs CAB in SDC

Recruiting
2
26
Europe
Goserelin 10.8 mg, Zoladex, Bicalutamide 50 mg, Casodex, Dutasteride 0.5 mg, Avodart
Radboud University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development
Salivary Duct Carcinoma
09/25
09/27
COMMENCE, NCT02054442 / 2013-002886-20: A Study of the Combination of Cetuximab and Methotrexate in Recurrent or Metastatic Cancer of the Head and Neck

Active, not recruiting
1/2
52
Europe
Cetuximab, Erbitux, L01XC06, Methotrexate, EMTHEXATE, L01BA01
Radboud University Medical Center, Merck Serono International SA, Leiden University Medical Center, Academisch Ziekenhuis Maastricht, Erasmus Medical Center, Medisch Spectrum Twente, Medical Center Haaglanden, Elisabeth-TweeSteden Ziekenhuis, Medical Centre Leeuwarden
Squamous Cell Carcinoma of the Head and Neck
12/21
12/22
MCLA-158-CL01, NCT03526835 / 2017-004745-24: A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Recruiting
1/2
523
Europe, US
MCLA-158, petosemtamab, MCLA-158 + Pembrolizumab, MCLA-158 + FOLFIRI, MCLA-158 + FOLFOX
Merus N.V., Merus N.V.
Advanced/Metastatic Solid Tumors, Colorectal Cancer, Gastric Cancer, Gastroesophageal-junction Cancer, NSCLC, HNSCC, Head and Neck Squamous Cell Carcinoma, Esophageal Cancer
11/25
11/27
SYLVER, NCT06710847: A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Recruiting
1/2
73
Japan, US
GSK4418959, PD-1 inhibitor
GlaxoSmithKline, IDEAYA Biosciences
Neoplasms, Colorectal, Solid Tumor, Colon Cancer, Rectal Cancer, Endometrial Cancer
02/27
06/28
DF1001-001, NCT04143711 / 2019-004706-10: Study of DF1001 in Patients With Advanced Solid Tumors

Recruiting
1/2
378
Europe, US
DF1001, Nivolumab, Nab paclitaxel, Sacituzumab Govitecan-hziy
Dragonfly Therapeutics, Dragonfly Therapeutics, Inc.
Solid Tumor, Adult
10/26
12/26
NCT05752552: Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients with Advanced or Refractory Solid Tumours

Recruiting
1
25
Europe
DO-2
DeuterOncology
Adult Solid Tumor, Advanced Solid Tumor, Refractory Tumor, Non-small Cell Lung Cancer, Non-small Cell Carcinoma, Lung Cancer, Hereditary Renal Papillary Cancer
12/25
12/26
ELVN-002-003, NCT06328738: ELVN-002 with Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer

Recruiting
1
275
Europe, US, RoW
ELVN-002, Trastuzumab, 5-Fluorouracil, Oxaliplatin, Capecitabine, Eribulin, paclitaxel, Leucovorin
Enliven Therapeutics
HER2-positive Breast Cancer, HER2-positive Gastric Cancer, HER2 Positive Solid Tumors, HER2 Amplification, Colorectal Cancer
01/27
07/28
BYON3521.001, NCT05323045: A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate BYON3521

Active, not recruiting
1
31
Europe
BYON3521
Byondis B.V.
Solid Tumor
07/24
07/24
ADT-SCAN, NCT04214353: PSMA-PET Imaging Before and After ADT in Advanced SDC Patients

Recruiting
N/A
14
Europe
68Ga-PSMA-PET/CT, 18FDG-PET/CT
Radboud University Medical Center, Dutch Cancer Society
Salivary Gland Cancer, Salivary Duct Carcinoma
05/23
09/23
Braam, Petra
E²-RADIatE, NCT03818503: E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe

Recruiting
N/A
2000
Europe, RoW
European Organisation for Research and Treatment of Cancer - EORTC
Cancer
04/26
04/26
SCOPES, NCT04425967: Short Course of Preoperative Radiotherapy in Head and Neck-, Trunk- and Extremity Soft Tissue Sarcomas

Recruiting
N/A
163
Europe
pre-operative radiotherapy, radiotherapy
The Netherlands Cancer Institute, Leiden University Medical Center
Soft Tissue Sarcomas
04/25
04/34
Vries, Joost de
FIRST, NCT04034810: Safety and Efficacy of Silk Vista and Silk Vista Baby Flow Diverter for Intracranial Aneurysm Treatment

Active, not recruiting
N/A
234
Europe, RoW
Intracranial aneurysm treated with Silk vista and silk vista baby
Balt Extrusion
Intracranial Aneurysm
03/23
11/27
Boogaarts, Hieronymus D
DIST, NCT05460793: Dutch Intracerebral Hemorrhage Surgery Trial

Recruiting
N/A
600
Europe
Minimally invasive endoscopy-guided surgery
Radboud University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development, Dutch National Health Care Institute, Penumbra Inc.
Intracerebral Hemorrhage, Minimally Invasive Surgical Procedures, Endoscopic Surgical Procedures
07/27
07/28
Blaauw, Ivo
APAC, NCT02848820 / 2016-003052-70: Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Children

Active, not recruiting
4
302
Europe
Augmentin + Gentamicin, Amoxicillin/clavulanic acid (Augmentin) + Gentamicin, Appendectomy
Ramon Gorter, ZonMw: The Netherlands Organisation for Health Research and Development, Amsterdam UMC, location VUmc
Appendicitis
12/24
12/24
CAPP, NCT04755179: Identification of the Optimal Treatment Strategy for Complex Appendicitis in the Pediatric Population

Completed
N/A
1308
Europe
Laparoscopic appendectomy, Open appendectomy, Non-operative treatment, Direct appendectomy
Ramon Gorter, ZonMw: The Netherlands Organisation for Health Research and Development, Amsterdam UMC, location VUmc
Appendicitis, Appendix Mass, Appendicitis Perforated
07/24
07/24
Withagen, Mariella IJ
SUPPORT, NCT05713422: Superiority of Perineoplasty as Concomitant Surgical Procedure During Pelvic Organ Prolapse Repair

Active, not recruiting
N/A
305
Europe
Marjolein Spiering, Spaarne Gasthuis
Pelvic Organ Prolapse
12/25
12/26
Kool, Leo Schultze
No trials found
Sevaux, R de
No trials found

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