TIGER, NCT04663750: Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (). |
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| Recruiting | 3 | 210 | Europe | Pars plana vitrectomy, Intravitreal 2 mg aflibercept (Eylea, Bayer) will be injected at baseline then monthly for two further doses, then 2-monthly until month 12, Aflibercept (Eylea, Bayer), subretinal injection of recombinant TPA (Alteplase) up to a maximum of 25 micrograms in 0.2 mls, Actilyse (Boehringer Ingelheim), Intravitreal 20% sulfahexafluoride (SF6) gas tamponade | King's College Hospital NHS Trust, King's College London, Fight for Sight (Funder) | Eye Diseases, Macular Degeneration, Wet, Sub-Macular Hemorrhage | 01/25 | 12/25 | | |
PROTEUS, NCT05028179: Evaluating the Use of Artificial Intelligence to Support Stress Echocardiography Testing for Heart Disease |
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| Active, not recruiting | N/A | 2338 | Europe | EchoGo | Ultromics Ltd, University of Oxford, Academic Health Science Centres, National Institute for Health Research, United Kingdom | Coronary Heart Disease | 06/23 | 12/23 | | |
