NYU Langone Health - Heart Rhythm Center
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 19 Trials 
112 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Chinitz, Larry
RIDGE-1, NCT06228924: Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults with PKP2 Mutation-associated ARVC

Recruiting
1
15
US
TN-401
Tenaya Therapeutics, Johns Hopkins University, Mayo Clinic
Arrhythmogenic Right Ventricular Cardiomyopathy
05/26
10/29
ERUCA, NCT04438395: Dielectric Tissue Imaging in Cavotricuspid Isthmus Ablation

Recruiting
N/A
30
US
Cardiac ablation via catheter
EPD Solutions, A Philips Company
Atrial Fibrillation and Flutter
06/22
06/22
RIDGE, NCT06311708: Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Recruiting
N/A
200
Europe, US
Tenaya Therapeutics, University of California, San Francisco, Brigham and Women's Hospital, New York University, University of Colorado, Denver, Johns Hopkins University, The Cleveland Clinic, Mayo Clinic, Medical University of South Carolina, Hopital Louis Pradel, Istituti Clinici Scientifici Maugeri SpA, The Queen Elizabeth Hospital, St George's University Hospitals NHS Foundation Trust, Royal Brompton & Harefield NHS Foundation Trust, Barts & The London NHS Trust, Skane University Hospital, Centro Cardiologico Monzino, Hôpital Haut-Lévêque, Nantes University Hospital, Pitié-Salpêtrière Hospital, Wuerzburg University Hospital, University Hospital Muenster
Arrhythmogenic Right Ventricular Cardiomyopathy
03/30
07/30
PSOT, NCT03481413: Patient Specific Optimized Therapy Post-Market Clinical Follow-up Study

Terminated
N/A
566
Europe, US, RoW
Ablation
EPD Solutions, A Philips Company
Arrythmia
03/23
03/23
ABT-CIP-10523, NCT06707688: Abbott Medical - VERITAS Study

Recruiting
N/A
475
Europe, Canada, US
Amulet™ 2 Left Atrial Appendage (LAA) Occluder
Abbott Medical Devices
Atrial Fibrillation (AF), Stoke
07/26
07/28
NCT06676072: A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF:

Recruiting
N/A
188
Europe, US
PFA Ablation catheter
Abbott Medical Devices
Atrial Fibrillation (AF), Atrial Arrhythmia, Paroxysmal AF, Drug Refractory Paroxysmal Atrial Fibrillation
04/26
04/26
ViewFlex X FIH, NCT06772493: ViewFlex X ICE First-in-Human Study

Recruiting
N/A
200
US
ViewFlex X ICE System
Abbott Medical Devices
Cardiac Arrhythmias
12/25
12/25
ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation

Active, not recruiting
N/A
669
Europe, Canada, US
Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System
Boston Scientific Corporation
Persistent Atrial Fibrillation
03/25
03/25
NCT05997446: Amulet™ ADVANCE LAA

Active, not recruiting
N/A
610
US
Left atrial appendage occlusion (LAAO)
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
06/27
06/27
NCT04502316: Real-World Experience - Barostim™ Advancing the Level of Clinical Evidence (REBALANCE Registry)

Active, not recruiting
N/A
5000
US
Barostim™ System
CVRx, Inc.
Heart Failure
06/28
06/28
LAAOS-4, NCT05963698: The Fourth Left Atrial Appendage Occlusion Study

Recruiting
N/A
4000
Europe, Canada, US
WATCHMAN device
Hamilton Health Sciences Corporation, McMaster University, Population Health Research Institute, Boston Scientific Corporation
Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
09/29
12/29
NCT06048731: Enlighten Study: the EV-ICD Post Approval Registry

Active, not recruiting
N/A
1000
Europe, Canada, US, RoW
Defibrillation using EV-ICD
Medtronic
Ventricular Arrhythmia, Tachycardia
05/30
10/37
Coordinator, Research
ONSET, NCT06986993: Impact of Semaglutide on Tobacco Use and Related Health Behaviors

Recruiting
4
40
US
Semaglutide, Ozempic, Placebo, Saline
University of Oklahoma
Tobacco Use
05/28
06/28
CAMPLIFE, NCT06562296: Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers

Active, not recruiting
4
292
US
Amnion-Intermediate-Chorion, AIC, Amnion-Chorion-Amnion, ACA, Standard of Care, SOC
Cellution Biologics, SerenaGroup, Inc., LifeCell
Diabetic Foot Ulcer, Venous Leg Ulcer
12/26
07/27
TOPAZ, NCT03924414: Trial of Parkinson's and Zoledronic Acid

Active, not recruiting
4
2650
US
Zoledronic Acid 5Mg/Bag 100Ml Inj, Reclast, Placebo
California Pacific Medical Center Research Institute, National Institute on Aging (NIA), University of California, San Francisco, Duke University, University of Pittsburgh, Parkinson's Foundation
Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia with Lewy Bodies
10/25
10/25
NCT05078827: Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Completed
3
458
US
Test Product (A): Fluorouracil Cream, 5% topical cream, Experimental, Reference Product (B): Fluorouracil 5% Topical Cream of Mylan Pharmaceuticals Inc., Morgantown, WV 26505 U.S.A., Active Comparator, Placebo Product (C): Test vehicle cream for fluorouracil 5% of Encube Ethicals Pvt. Ltd., India, Placebo Comparator
Encube Ethicals Pvt. Ltd., CBCC Global Research
Actinic Keratoses
11/22
12/22
ReMMi-D, NCT05853900: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine

Completed
3
558
US
ReMMi-D Digital Therapeutic
Click Therapeutics, Inc.
Migraine, Episodic Migraine, Headache, Headache, Migraine
05/24
05/24
OPERA-T, NCT05238116 / 2021-004554-32: Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis ( Study)

Recruiting
3
123
Europe, Canada, US, RoW
PC945, Placebo
Pulmocide Ltd
Refractory IPA
03/26
04/26
NCT06004388: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C)

Completed
3
110
US
Click Digital Therapeutic
Click Therapeutics, Inc.
Migraine, Episodic Migraine, Headache, Headache, Migraine
05/24
06/24
SKOAP, NCT04504812: A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

Completed
3
1937
US
Duloxetine, Cymbalta, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices
Johns Hopkins University, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Pacira Pharmaceuticals, Inc
Knee Osteoarthritis
04/25
04/25
CONVOKE, NCT05838625: Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia

Active, not recruiting
3
432
US
Digital Therapeutic
Click Therapeutics, Inc., Boehringer Ingelheim
Schizophrenia
06/25
07/25
NCT06067984: An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia

Active, not recruiting
3
75
US
Study App
Click Therapeutics, Inc., Boehringer Ingelheim
Schizophrenia, Negative Symptoms in Schizophrenia
06/25
06/25
STABLE-MATES, NCT02468024: JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

Recruiting
3
272
Europe, Canada, US, RoW
Lung Surgery, SR, Radiation therapy, SAbR
University of Texas Southwestern Medical Center
Non-Small Cell Lung Cancer
12/28
12/28
NCT06891300: Understanding and Treating Suicidal Ideation With Ketamine

Recruiting
2/3
36
Canada
ketamine hydrochloride
The Royal's Institute of Mental Health Research
Suicidal Ideation, Major Depressive Disorder (MDD)
10/26
10/26
HEALEY ALS, NCT04297683: Platform Trial - Master Protocol

Active, not recruiting
2/3
1500
US
ABBV-CLS-7262, DNL343
Merit E. Cudkowicz, MD, Massachusetts General Hospital
Amyotrophic Lateral Sclerosis
07/25
04/26
NCT06365437: A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

Completed
2
33
Europe
TCD601, Siplizumab, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG
ITB-Med LLC
Kidney Transplantation
12/24
12/24
PHYOX8, NCT05001269 / 2021-001083-16: Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function

Completed
2
25
Europe, Canada, Japan, US, RoW
nedosiran, DCR-PHXC
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Primary Hyperoxaluria, Primary Hyperoxaluria Type 1, Primary Hyperoxaluria Type 2, Primary Hyperoxaluria Type 3
02/25
02/25
NCT03651700: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia

Completed
2
86
US
Active TMS, Sham TMS, CILT, Constraint Induced Language Therapy
H. Branch Coslett, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD)
Aphasia
08/24
08/24
CHASE, NCT05727878: Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED

Recruiting
2
90
US, RoW
KPI-012, KPI-012 Vehicle
Combangio, Inc, Kala Pharmaceuticals, Inc.
Persistent Corneal Epithelial Defect
09/25
06/26
NCT05733546: A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder

Recruiting
2
102
US
Psilocybin, COMP360
COMPASS Pathways
Major Depressive Disorder
10/24
11/24
NCT04270175: Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Relapsed/Refractory Light Chain Amyloidosis Patients Previously Exposed to Daratumumab

Active, not recruiting
2
15
US
Daratumumab SC, Faspro, Pomalidomide, Dexamethasone
Weill Medical College of Cornell University, Janssen Scientific Affairs, LLC
Amyloid, AL Amyloidosis, Refractory AL Amyloidosis
09/25
09/27
NCT04803058: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PERSPECTIVE)

Active, not recruiting
2
18
US, RoW
TCD601
ITB-Med LLC
Kidney Transplantation
03/27
03/30
STRIDE, NCT06025110: A Study of TCD601 (siplizumab) in New Onset Type 1 Diabetes Patients

Active, not recruiting
2
96
Europe
TCD601, Placebo
ITB-Med LLC
Diabetes Mellitus, Type 1
01/27
01/27
NCT06709612: Postsurgical Analgesia After Hernia Repair

Not yet recruiting
2
30
Canada
AMT-143 hydrogel containing containing ropivacaine, AMT-143, Ropivacaine, Placebo
AmacaThera Inc.
Hernia, Hernia, Abdominal
03/26
05/26
STSINJ, NCT06672822: Intralesional Injection of STS in Treatment of Calcinosis

Recruiting
2
20
US
Sodium Thiosulfate (STS)
Robyn T. Domsic, MD, MPH, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Systemic Sclerosis (SSc), Dermatomyositis, Mixed Connective Tissue Disease (MCTD), Calcinosis
08/25
05/26
ASCEND, NCT05669001: A Study of TCD601 in de Novo Renal Transplant Recipients

Active, not recruiting
2
90
US
TCD601, siplizumab, belatacept, ATG, antithymocyte globulin, TAC, tacrolimus, MPA, mycophenolic acid, Corticosteroids
ITB-Med LLC
Renal Transplantation
07/25
10/26
NCT04311632: A Dose Escalation Study in de Novo Renal Transplantation

Completed
2
13
US
TCD601, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG
ITB-Med LLC
Kidney Transplantation
10/23
10/23
NCT04464980: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

Active, not recruiting
2
2190
US
SL-BUP, sublingual buprenorphine, Suboxone, XR-BUP, extended-release buprenorphine, CAM2038, Brixadi, XR-NTX, extended-release naltrexone, Vivitrol, MM, MMR, MMD
NYU Langone Health, New York State Psychiatric Institute, Columbia University, Harvard Medical School (HMS and HSDM), Mclean Hospital, National Institute on Drug Abuse (NIDA), The Emmes Company, LLC
Opioid Use Disorder (OUD)
12/26
12/26
NCT04803006: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PANORAMA)

Active, not recruiting
2
18
US
TCD601
ITB-Med LLC
Kidney Transplantation
07/27
07/30
NCT04892251: Ketamine Assisted Psychotherapy for Opioid Use Disorder

Recruiting
1/2
60
US
MORE+KAP, MORE
University of Utah
Opioid-use Disorder
12/23
05/24
NCT04482179: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease

Completed
1
23
US
Active TMS, CILT, Constraint Induced Language Therapy, Sham TMS
University of Pennsylvania, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD)
Alzheimer Disease
08/24
08/24
AURORA, NCT06453668: A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients

Active, not recruiting
1
48
Europe
TCD601, siplizumab
ITB-Med LLC
ALS
11/26
11/26
PBL-0405-01, NCT06273852: A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors

Recruiting
1
15
US
PBA-0405, PB004.22.0405.aF
Pure Biologics S.A., Presage Biosciences
Head and Neck Squamous Cell Carcinoma, Soft Tissue Sarcoma Adult, Triple Negative Breast Cancer
03/25
03/25
MST01-AZN-05, NCT06366451: PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC

Recruiting
1
15
US
Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, AZD9592, Pembrolizumab, Keytruda, MK-3475, AZD9592 + Rilvegostomig, AZD9592 + Volrustomig, AZD9592 + Sabestomig, AZD9592 + Pembrolizumab
Presage Biosciences, AstraZeneca
Head and Neck Squamous Cell Carcinoma
02/25
04/25
OP-1250-003, NCT05508906: Phase 1b Combo w/ Ribociclib, Alpelisib, or Everolimus

Recruiting
1
155
US, RoW
OP-1250, Ribociclib, KISQALI®, Alpelisib, PIQRAY®, Everolimus
Olema Pharmaceuticals, Inc., Novartis
Metastatic Breast Cancer, Advanced Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Breast Cancer
05/26
06/26
RAINIER, NCT06634394: APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

Recruiting
1
39
US
APVO436, Venetoclax, venclexta, Azacitidine, vidaza
Aptevo Therapeutics
Acute Myeloid Leukemia (AML)
10/27
03/28
NCT06798454: Single Ascending Dose Study to Evaluate Safety Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 in Healthy Subjects and Patients (PBC/PSC)

Recruiting
1
30
RoW
PVT201, Navacim, Placebo, normal saline, 0.9% NaCl
Parvus Therapeutics, Inc., Avance Clinical Pty Ltd.
Primary Biliary Cholangitis (PBC)
06/25
06/25
NCT05471609: Sustained Release Oral Formulation for Treatment of Parkinson's Disease

Recruiting
1
6
US
levodopa/carbidopa oral formulation A, levodopa/carbidopa oral formulation B
University of Minnesota
Idiopathic Parkinson Disease
06/26
06/26
NCT04541108: Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

Recruiting
1
15
US
Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, Pembrolizumab, Keytruda, MK-3475
Presage Biosciences, Merck Sharp & Dohme LLC
Solid Tumor
12/31
12/31
NCT06802328: Intermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS Patients

Available
N/A
US
Foralumab TZLS-401 50 µg
Tiziana Life Sciences LTD
Non-Active Secondary Progressive Multiple Sclerosis
 
 
Lublin, NCT06217081: [Trial of device that is not approved or cleared by the U.S. FDA]

Withheld
N/A
452
NA
3M Topical Tissue Adhesive, Histoacryl® Blue Topical Skin Adhesive
[Redacted], United States Department of Defense, The University of Texas Health Science Center at San Antonio, 3M
Trauma-related Wound, Surgical Incision, Surgical Wound, Laceration
 
 
NCT06129084: A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing

Recruiting
N/A
260
Canada
FGFR Testing
Bernie Eigl, Vancouver Prostate Centre, Lady Davis Institute, Bladder Cancer Canada
Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma
03/25
05/25
PRISM, NCT03953508: Perceptions of Cigarette Smoking in Young Adults

Completed
N/A
199
US
Cigarette flavor type, Experimental cigarette smoking
University of Oklahoma
Smoking, Cigarette
12/22
01/23
NCT03869463: Computerized Cognitive Training in Young Adults With Depression

Terminated
N/A
28
US
Computerized Cognitive Training, Control
Queens College, The City University of New York
Depressive Symptoms
03/23
03/23
NCT03495011: MRI Characterization of Mammographically Detected DCIS

Active, not recruiting
N/A
122
US
Breast MRI, Laboratory Biomarker Analysis, Oncotype Dx
University of Washington, National Cancer Institute (NCI), National Institutes of Health (NIH)
Breast Cancer, Stage 0
04/23
04/32
NCT05004389: Biomarkers of Independent Walking Post-Stroke

Recruiting
N/A
35
US
MRI, blood draw, Clinical assessments
University of Vermont, National Institute of General Medical Sciences (NIGMS)
Stroke, Acute, Gait, Hemiplegic
05/23
05/23
NCT04902339: Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain

Completed
N/A
142
US
Mindfulness-Oriented Recovery Enhancement, Neurofeedback, Supportive Psychotherapy
University of Utah
Chronic Pain Syndrome, Opioid Use
04/25
04/25
NCT04088773: Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease

Active, not recruiting
N/A
232
US
blood biomarkers, stool biomarkers, MRI imaging
Children's Hospital Medical Center, Cincinnati, The Leona M. and Harry B. Helmsley Charitable Trust
Crohn Disease
09/23
06/26
NCT06136936: A Study to Evaluate the Overall Effects of Treatment With Abbreviated CT-156 in People With Schizophrenia

Completed
N/A
53
US
CT-156-C-001
Click Therapeutics, Inc., Boehringer Ingelheim
Schizophrenia
01/24
02/24
NCT05222581: Engineering Evaluation of a Breast Pump Device

Completed
N/A
48
US
Prototypes of breast shield and Freedom Double Electric Breast Pump
Momtech Inc.
Healthy, Breast Pumping
06/24
09/24
NCT06136923: An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer

Completed
N/A
194
US
CT-100-D-004-A, CT-100-D-004-B
Click Therapeutics, Inc.
Multiple Sclerosis, Lung Cancer, Breast Cancer
04/24
05/24
NCT05465395: Upper Cervical and Thoracic Chiropractic Adjustment

Suspended
N/A
40
US
Upper Cervical Adjustemnt, Thoracic Adjustemnt
Life University
Stress
11/23
11/23
LOCAL, NCT04968847: FemaSeed Artificial Insemination Trial

Completed
N/A
314
US
FemaSeed Localized Directional Insemination
Femasys Inc.
Infertility, Male Factor
12/23
04/24
CT-100-D-003, NCT06275659: An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis

Completed
N/A
120
US
CT-100-004-A, CT-100-004-B
Click Therapeutics, Inc.
Psoriasis, Atopic Dermatitis
02/24
02/24
NCT05617300: Mindfulness-based Dementia Care Partner Program to Reduce Depressive Symptoms

Completed
N/A
130
US
Mindfulness-Based Dementia Caregiving
HealthPartners Institute
Dementia
12/23
03/24
NCT04685044: Testing a 32-channel Transmit/Receive MRI Head Array

Active, not recruiting
N/A
15
Canada
IH 1Tx32Rx Head Array
Lawson Health Research Institute
Magnetic Resonance Imaging
12/23
12/23
NCT04340947: Cigarette Smoking Among Young Adults

Completed
N/A
172
US
Very low nicotine cigarettes
University of Oklahoma
Cigarette Smoking, Smoking Behaviors
03/24
04/24
NCT03303248: Evaluation of Web-based Transition Education to Enhance Transition Readiness

Active, not recruiting
N/A
180
US
Web-based Educational Intervention
University of Michigan, University of Nebraska
Congenital Heart Disease, Transition, Pediatric Congenital Heart Disease
06/25
06/25
NCT05119842: APrevent-VOIS-Implant-002 - a Two-Part, Open-Label, Non-Randomized Multicenter Study

Recruiting
N/A
30
Europe, US
APrevent® VOIS-Implant
APrevent Biotech GmbH
Paralysis, Unilateral, Vocal Cord
09/25
09/26
BACS, NCT04063384: Acute Alcohol Response In Bipolar Disorder: a fMRI Study

Completed
N/A
60
US
alcohol beverage, Placebo beverage
University of Texas at Austin
Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
03/24
03/24
NCT04625959: Optimizing Mindfulness and Acceptance Based Behavioral Treatment for Bulimia Nervosa and Binge Eating Disorder

Active, not recruiting
N/A
256
US
Behavioral Therapy for Eating Disorders, MABT: Mindful Awareness, MABT: Values, MABT: Emotion Modulation, MABT: Distress Tolerance
Drexel University, National Institute of Mental Health (NIMH)
Bulimia Nervosa, Bulimia; Atypical, Binge-Eating Disorder, Binge-Eating and Purging Type Anorexia Nervosa, Binge Eating
04/24
04/24
NCT06330246: O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

Recruiting
N/A
40
US
Low oxalate fixed diets pre-colonization, Moderately high oxalate fixed diets pre-colonization, Colonization with Oxalobacter formigenes, Low oxalate fixed diets post-colonization, Moderately high oxalate fixed diets post-colonization
University of Alabama at Birmingham, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria
12/30
12/31
NCT06331546: Gut Oxalate Absorption in Calcium Oxalate Stone Disease

Recruiting
N/A
80
US
Low-oxalate diet, High-oxalate diet, soluble oxalate gut absorption test
University of Alabama at Birmingham, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria, Healthy
12/30
12/31
SWAT, NCT06588101: Clinical Trial Recruitment and Retention Strategies for Family Members in the ICU

Recruiting
N/A
160
Canada
Written informed consent with infographic, Compensation
Lady Davis Institute, Canadian Institutes of Health Research (CIHR)
Family Members, Recruitment, Clinical Study, Retention, Recruitment of Participants, Study Enrollment, Retention of Participants, Compensation Incentives
04/26
12/26
NCT06431386: Behavioural Activation Therapy and Esketamine for Resistant Depression

Recruiting
N/A
40
Canada
Behavioural Activation (BA) Therapy, Esketamine
The Royal's Institute of Mental Health Research
Depressive Disorder, Treatment-Resistant, Depressive Disorder, Major, Bipolar Disorder
08/26
08/26
FACS, NCT04716036: Familial Risk for Bipolar Disorder and Alcohol Sensitivity

Completed
N/A
68
US
Alcohol beverage, Placebo beverage
University of Texas at Austin
Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
06/24
06/24
NCT04279483: GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments

Completed
N/A
336
US
Tobacco retailer, Non-tobacco retailer
Abramson Cancer Center at Penn Medicine, National Cancer Institute (NCI), New York University, Stanford University
Smoking, Tobacco, Smoking, Smoking, Cigarette
06/24
06/24
NCT05884437: The Effects of Chiropractic in Adults With Metabolic Syndrome

Suspended
N/A
10
US
Chiropractic adjustment
Life University
Metabolic Syndrome
07/25
12/25
NCT06385392: Continuous Wearable Monitor for the Detection and Release of Freezing of Gait.

Completed
N/A
31
US
Haptic module and insole device
HealthPartners Institute
Parkinson Disease
04/25
04/25
I-YMSC, NCT06657950: Treatments for Improving Mood in Women Survivors of Interpersonal Violence: A Community-Engaged Study-1.2

Completed
N/A
11
US
Integrative hatha yoga and mindful self-compassion
Butler Hospital, National Center for Complementary and Integrative Health (NCCIH)
Distress
05/25
05/25
NCT06172660: Real-World Effectiveness of Perinatal RSV Immunoprophylaxis

Recruiting
N/A
3750
US
Nirsevimab, RSV vaccines
Yale University, National Institute of Allergy and Infectious Diseases (NIAID)
RSV Infection
12/28
12/28
DETECT-POAF, NCT06519747: DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery

Recruiting
N/A
750
Canada
Cardiac monitoring device
Population Health Research Institute
Atrial Fibrillation, Atrial Flutter
08/26
12/26
SiESTa 2, NCT06336590: Student Exercise and Sleep Timing Study - Part 2

Recruiting
N/A
62
US
Morning Exercise
Rutgers, The State University of New Jersey
Sleep, Mood, Stress
12/26
12/26
NCT03556683: Phase I Assessment of Hypertonic Saline in Moderate to Severe Asthmatics

Completed
N/A
22
US
3% Hypertonic Saline, 7% Hypertonic Saline
University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI)
Moderate to Severe Asthma
06/24
06/24
NCT06907888: Rhythm Express Wearable System vs. Simultaneous Polysomnography for the Diagnosis of Obstructive Sleep Apnea in Adults With Suspected or Observed Atrial Fibrillation

Recruiting
N/A
30
US
Rhythm Express Wearable System
VivaQuant
Obstructive Sleep Apnea (OSA), Atrial Fibrillation (Paroxysmal), Palpitations
05/25
05/25
CoMind EFS, NCT06368648: CoMind Early Feasibility Study

Recruiting
N/A
581
US
CoMind Technologies Limited, Lindus Health
Intracranial Pressure, Intracranial Pressure Changes, Traumatic Brain Injury, Intracerebral Hemorrhage, Encephalitis, Encephalopathy, Hydrocephalus, Stroke, Autoregulation
10/25
10/25
NCT05006404: Autus Valve Pivotal Study

Recruiting
N/A
50
US
Pulmonary Valve Replacement Surgery
Autus Valve Technologies, Inc.
Congenital Heart Disease
08/26
02/36
URBI, NCT06560021: Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

Enrolling by invitation
N/A
1642
US
Biopsy strategy
University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
12/28
06/29
MASTR, NCT05243966: Myriad™ Augmented Soft Tissue Reconstruction Registry

Recruiting
N/A
800
US
Myriad Matrix™ and Myriad Morcells™
Aroa Biosurgery Limited
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus, Anal Fistula, Hidradenitis Suppurativa, Pressure Injury
01/28
01/29
NCT06770998: A Study of a Novel EEG Neurofeedback System for PTSD Treatment

Not yet recruiting
N/A
250
US
EEG-neurofeedback training, Prism training, amyg-EFP training, active Prism training, Sham training, sham Prism training
Foundation for Atlanta Veterans Education and Research, Inc., GrayMatters Health Ltd., Rochester Institute of Technology, New York University Grossman School of Medicine, Atlanta VA Medical Center, Birmingham VA Health Care System, Ralph H. Johnson VA Medical Center, VA Boston Healthcare System, CTP Inc, BioStats Statistical Consulting Ltd, ShareCRF, United States Department of Defense
Stress Disorders, Post-Traumatic
06/27
08/27
THRIVE, NCT06843213: Teaching Harm Reduction in a Hospital Setting: A Peer-led Intervention

Recruiting
N/A
390
US
Peer Intervention, Enhanced Usual Care
University of Pennsylvania, National Institute on Drug Abuse (NIDA), University of Pittsburgh
Opioid Use Disorder, Harm Reduction
08/27
12/28
MOUD+, NCT06837662: The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients with Opioid Use Disorder Seen in Primary Care

Not yet recruiting
N/A
70
US
MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), collaborative care, integrated behavioral health, MOUD Plus, Treatment As Usual (primary care with low threshold MOUD prescribing), usual care, treatment as usual, low-threshold MOUD prescribing
Oregon Health and Science University, National Institute on Drug Abuse (NIDA), Central City Concern
Opioid Dependence, Substance Abuse Disorders, Complex Medical Patients, Primary Care Patients with Chronic Conditions
03/26
11/26
FASTR-TEN, NCT06867185: Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries

Recruiting
N/A
60
US
Brief Electrical Stimulation Therapy, BES, Therapeutic Electrical Stimulation, Electrical Stimulation, Digital Nerve Repair, Nerve Repair
Checkpoint Surgical Inc.
Digital Nerve Injury, Nerve Injury, Nerve Reconstruction, Nerve Trauma, Digital Nerve Lesion
12/26
03/27
NCT06989320: Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

Recruiting
N/A
80
US
Low-oxalate diet and glycolate dosing, Oral glycolate dosing, Oral 13C- ascorbic acid dosing
University of Alabama at Birmingham, University of Texas, Southwestern Medical Center at Dallas, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Kidney Stones, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Healthy, Healthy Volunteer
12/30
12/31
SARE-A, NCT05738837: An Evaluation of a Sexual Assault Resistance Program for Adolescent Girls

Recruiting
N/A
900
Canada
A-EAAA Sexual Assault Resistance Education Program immediately, Girls -- Flip the Script with EAAA, Usual care + A-EAAA at 6 months
University of Windsor, Public Health Agency of Canada (PHAC)
Sexual Assault
12/25
12/25
NCT06999330: TMS in Anxiety-Parkinson's Disease

Not yet recruiting
N/A
15
US
Theta burst stimulation active coil, Transmagnetic stimulation, MagVenture, Sham coil
HealthPartners Institute
Parkinsons Disease (PD), Anxiety
12/27
03/28
NCT06880731: Training Inner Speech in Children With Developmental Language Disorder

Recruiting
N/A
75
US
Modeling with Verbal Mediation, Modeling Only
MGH Institute of Health Professions, National Institute on Deafness and Other Communication Disorders (NIDCD)
Developmental Language Disorder
03/28
03/28
NCT05984680: COPD Care Pathway Among Patients With Cancer

Recruiting
N/A
100
US
Observational Phase 1, Observational Phase 2, Group I, Observational Phase 2, Group II, Observational Phase 3
Wake Forest University Health Sciences, National Cancer Institute (NCI), National Center for Advancing Translational Sciences (NCATS)
Chronic Obstructive Pulmonary Disease, Lung Cancer, Head and Neck Cancer
03/26
03/26
NCT05893927: Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes

Recruiting
N/A
120
US
Diabetes education web site application
The Reading Hospital and Medical Center, Reading Hospital Foundation, Complete Statistical Services (Consult-Stat)
Diabetes Mellitus, Type 2, Diabetes Education, Lifestyle Modification
09/25
09/25
PHONES, NCT04662320: Promoting Healing of Nerves Through Electrical Stimulation

Active, not recruiting
N/A
100
US
Checkpoint BEST System, Brief Electrical Stimulation (BES) Therapy
Checkpoint Surgical Inc., Congressionally Directed Medical Research Programs
Cubital Tunnel Syndrome, Nerve Compression, Nerve Injury, Ulnar Neuropathies
12/25
12/25
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Chinitz, Larry
RIDGE-1, NCT06228924: Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults with PKP2 Mutation-associated ARVC

Recruiting
1
15
US
TN-401
Tenaya Therapeutics, Johns Hopkins University, Mayo Clinic
Arrhythmogenic Right Ventricular Cardiomyopathy
05/26
10/29
ERUCA, NCT04438395: Dielectric Tissue Imaging in Cavotricuspid Isthmus Ablation

Recruiting
N/A
30
US
Cardiac ablation via catheter
EPD Solutions, A Philips Company
Atrial Fibrillation and Flutter
06/22
06/22
RIDGE, NCT06311708: Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Recruiting
N/A
200
Europe, US
Tenaya Therapeutics, University of California, San Francisco, Brigham and Women's Hospital, New York University, University of Colorado, Denver, Johns Hopkins University, The Cleveland Clinic, Mayo Clinic, Medical University of South Carolina, Hopital Louis Pradel, Istituti Clinici Scientifici Maugeri SpA, The Queen Elizabeth Hospital, St George's University Hospitals NHS Foundation Trust, Royal Brompton & Harefield NHS Foundation Trust, Barts & The London NHS Trust, Skane University Hospital, Centro Cardiologico Monzino, Hôpital Haut-Lévêque, Nantes University Hospital, Pitié-Salpêtrière Hospital, Wuerzburg University Hospital, University Hospital Muenster
Arrhythmogenic Right Ventricular Cardiomyopathy
03/30
07/30
PSOT, NCT03481413: Patient Specific Optimized Therapy Post-Market Clinical Follow-up Study

Terminated
N/A
566
Europe, US, RoW
Ablation
EPD Solutions, A Philips Company
Arrythmia
03/23
03/23
ABT-CIP-10523, NCT06707688: Abbott Medical - VERITAS Study

Recruiting
N/A
475
Europe, Canada, US
Amulet™ 2 Left Atrial Appendage (LAA) Occluder
Abbott Medical Devices
Atrial Fibrillation (AF), Stoke
07/26
07/28
NCT06676072: A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF:

Recruiting
N/A
188
Europe, US
PFA Ablation catheter
Abbott Medical Devices
Atrial Fibrillation (AF), Atrial Arrhythmia, Paroxysmal AF, Drug Refractory Paroxysmal Atrial Fibrillation
04/26
04/26
ViewFlex X FIH, NCT06772493: ViewFlex X ICE First-in-Human Study

Recruiting
N/A
200
US
ViewFlex X ICE System
Abbott Medical Devices
Cardiac Arrhythmias
12/25
12/25
ADVANTAGE AF, NCT05443594: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation

Active, not recruiting
N/A
669
Europe, Canada, US
Phase 1: FARAPULSE Ablation System, Phase 2: FARAPULSE Ablation System
Boston Scientific Corporation
Persistent Atrial Fibrillation
03/25
03/25
NCT05997446: Amulet™ ADVANCE LAA

Active, not recruiting
N/A
610
US
Left atrial appendage occlusion (LAAO)
Abbott Medical Devices
Atrial Fibrillation, Stroke, Bleeding
06/27
06/27
NCT04502316: Real-World Experience - Barostim™ Advancing the Level of Clinical Evidence (REBALANCE Registry)

Active, not recruiting
N/A
5000
US
Barostim™ System
CVRx, Inc.
Heart Failure
06/28
06/28
LAAOS-4, NCT05963698: The Fourth Left Atrial Appendage Occlusion Study

Recruiting
N/A
4000
Europe, Canada, US
WATCHMAN device
Hamilton Health Sciences Corporation, McMaster University, Population Health Research Institute, Boston Scientific Corporation
Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
09/29
12/29
NCT06048731: Enlighten Study: the EV-ICD Post Approval Registry

Active, not recruiting
N/A
1000
Europe, Canada, US, RoW
Defibrillation using EV-ICD
Medtronic
Ventricular Arrhythmia, Tachycardia
05/30
10/37
Coordinator, Research
ONSET, NCT06986993: Impact of Semaglutide on Tobacco Use and Related Health Behaviors

Recruiting
4
40
US
Semaglutide, Ozempic, Placebo, Saline
University of Oklahoma
Tobacco Use
05/28
06/28
CAMPLIFE, NCT06562296: Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers

Active, not recruiting
4
292
US
Amnion-Intermediate-Chorion, AIC, Amnion-Chorion-Amnion, ACA, Standard of Care, SOC
Cellution Biologics, SerenaGroup, Inc., LifeCell
Diabetic Foot Ulcer, Venous Leg Ulcer
12/26
07/27
TOPAZ, NCT03924414: Trial of Parkinson's and Zoledronic Acid

Active, not recruiting
4
2650
US
Zoledronic Acid 5Mg/Bag 100Ml Inj, Reclast, Placebo
California Pacific Medical Center Research Institute, National Institute on Aging (NIA), University of California, San Francisco, Duke University, University of Pittsburgh, Parkinson's Foundation
Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia with Lewy Bodies
10/25
10/25
NCT05078827: Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Completed
3
458
US
Test Product (A): Fluorouracil Cream, 5% topical cream, Experimental, Reference Product (B): Fluorouracil 5% Topical Cream of Mylan Pharmaceuticals Inc., Morgantown, WV 26505 U.S.A., Active Comparator, Placebo Product (C): Test vehicle cream for fluorouracil 5% of Encube Ethicals Pvt. Ltd., India, Placebo Comparator
Encube Ethicals Pvt. Ltd., CBCC Global Research
Actinic Keratoses
11/22
12/22
ReMMi-D, NCT05853900: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine

Completed
3
558
US
ReMMi-D Digital Therapeutic
Click Therapeutics, Inc.
Migraine, Episodic Migraine, Headache, Headache, Migraine
05/24
05/24
OPERA-T, NCT05238116 / 2021-004554-32: Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis ( Study)

Recruiting
3
123
Europe, Canada, US, RoW
PC945, Placebo
Pulmocide Ltd
Refractory IPA
03/26
04/26
NCT06004388: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C)

Completed
3
110
US
Click Digital Therapeutic
Click Therapeutics, Inc.
Migraine, Episodic Migraine, Headache, Headache, Migraine
05/24
06/24
SKOAP, NCT04504812: A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

Completed
3
1937
US
Duloxetine, Cymbalta, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices
Johns Hopkins University, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Pacira Pharmaceuticals, Inc
Knee Osteoarthritis
04/25
04/25
CONVOKE, NCT05838625: Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia

Active, not recruiting
3
432
US
Digital Therapeutic
Click Therapeutics, Inc., Boehringer Ingelheim
Schizophrenia
06/25
07/25
NCT06067984: An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia

Active, not recruiting
3
75
US
Study App
Click Therapeutics, Inc., Boehringer Ingelheim
Schizophrenia, Negative Symptoms in Schizophrenia
06/25
06/25
STABLE-MATES, NCT02468024: JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

Recruiting
3
272
Europe, Canada, US, RoW
Lung Surgery, SR, Radiation therapy, SAbR
University of Texas Southwestern Medical Center
Non-Small Cell Lung Cancer
12/28
12/28
NCT06891300: Understanding and Treating Suicidal Ideation With Ketamine

Recruiting
2/3
36
Canada
ketamine hydrochloride
The Royal's Institute of Mental Health Research
Suicidal Ideation, Major Depressive Disorder (MDD)
10/26
10/26
HEALEY ALS, NCT04297683: Platform Trial - Master Protocol

Active, not recruiting
2/3
1500
US
ABBV-CLS-7262, DNL343
Merit E. Cudkowicz, MD, Massachusetts General Hospital
Amyotrophic Lateral Sclerosis
07/25
04/26
NCT06365437: A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

Completed
2
33
Europe
TCD601, Siplizumab, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG
ITB-Med LLC
Kidney Transplantation
12/24
12/24
PHYOX8, NCT05001269 / 2021-001083-16: Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function

Completed
2
25
Europe, Canada, Japan, US, RoW
nedosiran, DCR-PHXC
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Primary Hyperoxaluria, Primary Hyperoxaluria Type 1, Primary Hyperoxaluria Type 2, Primary Hyperoxaluria Type 3
02/25
02/25
NCT03651700: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia

Completed
2
86
US
Active TMS, Sham TMS, CILT, Constraint Induced Language Therapy
H. Branch Coslett, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD)
Aphasia
08/24
08/24
CHASE, NCT05727878: Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED

Recruiting
2
90
US, RoW
KPI-012, KPI-012 Vehicle
Combangio, Inc, Kala Pharmaceuticals, Inc.
Persistent Corneal Epithelial Defect
09/25
06/26
NCT05733546: A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder

Recruiting
2
102
US
Psilocybin, COMP360
COMPASS Pathways
Major Depressive Disorder
10/24
11/24
NCT04270175: Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Relapsed/Refractory Light Chain Amyloidosis Patients Previously Exposed to Daratumumab

Active, not recruiting
2
15
US
Daratumumab SC, Faspro, Pomalidomide, Dexamethasone
Weill Medical College of Cornell University, Janssen Scientific Affairs, LLC
Amyloid, AL Amyloidosis, Refractory AL Amyloidosis
09/25
09/27
NCT04803058: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PERSPECTIVE)

Active, not recruiting
2
18
US, RoW
TCD601
ITB-Med LLC
Kidney Transplantation
03/27
03/30
STRIDE, NCT06025110: A Study of TCD601 (siplizumab) in New Onset Type 1 Diabetes Patients

Active, not recruiting
2
96
Europe
TCD601, Placebo
ITB-Med LLC
Diabetes Mellitus, Type 1
01/27
01/27
NCT06709612: Postsurgical Analgesia After Hernia Repair

Not yet recruiting
2
30
Canada
AMT-143 hydrogel containing containing ropivacaine, AMT-143, Ropivacaine, Placebo
AmacaThera Inc.
Hernia, Hernia, Abdominal
03/26
05/26
STSINJ, NCT06672822: Intralesional Injection of STS in Treatment of Calcinosis

Recruiting
2
20
US
Sodium Thiosulfate (STS)
Robyn T. Domsic, MD, MPH, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Systemic Sclerosis (SSc), Dermatomyositis, Mixed Connective Tissue Disease (MCTD), Calcinosis
08/25
05/26
ASCEND, NCT05669001: A Study of TCD601 in de Novo Renal Transplant Recipients

Active, not recruiting
2
90
US
TCD601, siplizumab, belatacept, ATG, antithymocyte globulin, TAC, tacrolimus, MPA, mycophenolic acid, Corticosteroids
ITB-Med LLC
Renal Transplantation
07/25
10/26
NCT04311632: A Dose Escalation Study in de Novo Renal Transplantation

Completed
2
13
US
TCD601, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG
ITB-Med LLC
Kidney Transplantation
10/23
10/23
NCT04464980: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)

Active, not recruiting
2
2190
US
SL-BUP, sublingual buprenorphine, Suboxone, XR-BUP, extended-release buprenorphine, CAM2038, Brixadi, XR-NTX, extended-release naltrexone, Vivitrol, MM, MMR, MMD
NYU Langone Health, New York State Psychiatric Institute, Columbia University, Harvard Medical School (HMS and HSDM), Mclean Hospital, National Institute on Drug Abuse (NIDA), The Emmes Company, LLC
Opioid Use Disorder (OUD)
12/26
12/26
NCT04803006: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PANORAMA)

Active, not recruiting
2
18
US
TCD601
ITB-Med LLC
Kidney Transplantation
07/27
07/30
NCT04892251: Ketamine Assisted Psychotherapy for Opioid Use Disorder

Recruiting
1/2
60
US
MORE+KAP, MORE
University of Utah
Opioid-use Disorder
12/23
05/24
NCT04482179: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease

Completed
1
23
US
Active TMS, CILT, Constraint Induced Language Therapy, Sham TMS
University of Pennsylvania, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD)
Alzheimer Disease
08/24
08/24
AURORA, NCT06453668: A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients

Active, not recruiting
1
48
Europe
TCD601, siplizumab
ITB-Med LLC
ALS
11/26
11/26
PBL-0405-01, NCT06273852: A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors

Recruiting
1
15
US
PBA-0405, PB004.22.0405.aF
Pure Biologics S.A., Presage Biosciences
Head and Neck Squamous Cell Carcinoma, Soft Tissue Sarcoma Adult, Triple Negative Breast Cancer
03/25
03/25
MST01-AZN-05, NCT06366451: PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC

Recruiting
1
15
US
Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, AZD9592, Pembrolizumab, Keytruda, MK-3475, AZD9592 + Rilvegostomig, AZD9592 + Volrustomig, AZD9592 + Sabestomig, AZD9592 + Pembrolizumab
Presage Biosciences, AstraZeneca
Head and Neck Squamous Cell Carcinoma
02/25
04/25
OP-1250-003, NCT05508906: Phase 1b Combo w/ Ribociclib, Alpelisib, or Everolimus

Recruiting
1
155
US, RoW
OP-1250, Ribociclib, KISQALI®, Alpelisib, PIQRAY®, Everolimus
Olema Pharmaceuticals, Inc., Novartis
Metastatic Breast Cancer, Advanced Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Breast Cancer
05/26
06/26
RAINIER, NCT06634394: APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

Recruiting
1
39
US
APVO436, Venetoclax, venclexta, Azacitidine, vidaza
Aptevo Therapeutics
Acute Myeloid Leukemia (AML)
10/27
03/28
NCT06798454: Single Ascending Dose Study to Evaluate Safety Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 in Healthy Subjects and Patients (PBC/PSC)

Recruiting
1
30
RoW
PVT201, Navacim, Placebo, normal saline, 0.9% NaCl
Parvus Therapeutics, Inc., Avance Clinical Pty Ltd.
Primary Biliary Cholangitis (PBC)
06/25
06/25
NCT05471609: Sustained Release Oral Formulation for Treatment of Parkinson's Disease

Recruiting
1
6
US
levodopa/carbidopa oral formulation A, levodopa/carbidopa oral formulation B
University of Minnesota
Idiopathic Parkinson Disease
06/26
06/26
NCT04541108: Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

Recruiting
1
15
US
Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, Pembrolizumab, Keytruda, MK-3475
Presage Biosciences, Merck Sharp & Dohme LLC
Solid Tumor
12/31
12/31
NCT06802328: Intermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS Patients

Available
N/A
US
Foralumab TZLS-401 50 µg
Tiziana Life Sciences LTD
Non-Active Secondary Progressive Multiple Sclerosis
 
 
Lublin, NCT06217081: [Trial of device that is not approved or cleared by the U.S. FDA]

Withheld
N/A
452
NA
3M Topical Tissue Adhesive, Histoacryl® Blue Topical Skin Adhesive
[Redacted], United States Department of Defense, The University of Texas Health Science Center at San Antonio, 3M
Trauma-related Wound, Surgical Incision, Surgical Wound, Laceration
 
 
NCT06129084: A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing

Recruiting
N/A
260
Canada
FGFR Testing
Bernie Eigl, Vancouver Prostate Centre, Lady Davis Institute, Bladder Cancer Canada
Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma
03/25
05/25
PRISM, NCT03953508: Perceptions of Cigarette Smoking in Young Adults

Completed
N/A
199
US
Cigarette flavor type, Experimental cigarette smoking
University of Oklahoma
Smoking, Cigarette
12/22
01/23
NCT03869463: Computerized Cognitive Training in Young Adults With Depression

Terminated
N/A
28
US
Computerized Cognitive Training, Control
Queens College, The City University of New York
Depressive Symptoms
03/23
03/23
NCT03495011: MRI Characterization of Mammographically Detected DCIS

Active, not recruiting
N/A
122
US
Breast MRI, Laboratory Biomarker Analysis, Oncotype Dx
University of Washington, National Cancer Institute (NCI), National Institutes of Health (NIH)
Breast Cancer, Stage 0
04/23
04/32
NCT05004389: Biomarkers of Independent Walking Post-Stroke

Recruiting
N/A
35
US
MRI, blood draw, Clinical assessments
University of Vermont, National Institute of General Medical Sciences (NIGMS)
Stroke, Acute, Gait, Hemiplegic
05/23
05/23
NCT04902339: Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain

Completed
N/A
142
US
Mindfulness-Oriented Recovery Enhancement, Neurofeedback, Supportive Psychotherapy
University of Utah
Chronic Pain Syndrome, Opioid Use
04/25
04/25
NCT04088773: Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease

Active, not recruiting
N/A
232
US
blood biomarkers, stool biomarkers, MRI imaging
Children's Hospital Medical Center, Cincinnati, The Leona M. and Harry B. Helmsley Charitable Trust
Crohn Disease
09/23
06/26
NCT06136936: A Study to Evaluate the Overall Effects of Treatment With Abbreviated CT-156 in People With Schizophrenia

Completed
N/A
53
US
CT-156-C-001
Click Therapeutics, Inc., Boehringer Ingelheim
Schizophrenia
01/24
02/24
NCT05222581: Engineering Evaluation of a Breast Pump Device

Completed
N/A
48
US
Prototypes of breast shield and Freedom Double Electric Breast Pump
Momtech Inc.
Healthy, Breast Pumping
06/24
09/24
NCT06136923: An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer

Completed
N/A
194
US
CT-100-D-004-A, CT-100-D-004-B
Click Therapeutics, Inc.
Multiple Sclerosis, Lung Cancer, Breast Cancer
04/24
05/24
NCT05465395: Upper Cervical and Thoracic Chiropractic Adjustment

Suspended
N/A
40
US
Upper Cervical Adjustemnt, Thoracic Adjustemnt
Life University
Stress
11/23
11/23
LOCAL, NCT04968847: FemaSeed Artificial Insemination Trial

Completed
N/A
314
US
FemaSeed Localized Directional Insemination
Femasys Inc.
Infertility, Male Factor
12/23
04/24
CT-100-D-003, NCT06275659: An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis

Completed
N/A
120
US
CT-100-004-A, CT-100-004-B
Click Therapeutics, Inc.
Psoriasis, Atopic Dermatitis
02/24
02/24
NCT05617300: Mindfulness-based Dementia Care Partner Program to Reduce Depressive Symptoms

Completed
N/A
130
US
Mindfulness-Based Dementia Caregiving
HealthPartners Institute
Dementia
12/23
03/24
NCT04685044: Testing a 32-channel Transmit/Receive MRI Head Array

Active, not recruiting
N/A
15
Canada
IH 1Tx32Rx Head Array
Lawson Health Research Institute
Magnetic Resonance Imaging
12/23
12/23
NCT04340947: Cigarette Smoking Among Young Adults

Completed
N/A
172
US
Very low nicotine cigarettes
University of Oklahoma
Cigarette Smoking, Smoking Behaviors
03/24
04/24
NCT03303248: Evaluation of Web-based Transition Education to Enhance Transition Readiness

Active, not recruiting
N/A
180
US
Web-based Educational Intervention
University of Michigan, University of Nebraska
Congenital Heart Disease, Transition, Pediatric Congenital Heart Disease
06/25
06/25
NCT05119842: APrevent-VOIS-Implant-002 - a Two-Part, Open-Label, Non-Randomized Multicenter Study

Recruiting
N/A
30
Europe, US
APrevent® VOIS-Implant
APrevent Biotech GmbH
Paralysis, Unilateral, Vocal Cord
09/25
09/26
BACS, NCT04063384: Acute Alcohol Response In Bipolar Disorder: a fMRI Study

Completed
N/A
60
US
alcohol beverage, Placebo beverage
University of Texas at Austin
Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
03/24
03/24
NCT04625959: Optimizing Mindfulness and Acceptance Based Behavioral Treatment for Bulimia Nervosa and Binge Eating Disorder

Active, not recruiting
N/A
256
US
Behavioral Therapy for Eating Disorders, MABT: Mindful Awareness, MABT: Values, MABT: Emotion Modulation, MABT: Distress Tolerance
Drexel University, National Institute of Mental Health (NIMH)
Bulimia Nervosa, Bulimia; Atypical, Binge-Eating Disorder, Binge-Eating and Purging Type Anorexia Nervosa, Binge Eating
04/24
04/24
NCT06330246: O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

Recruiting
N/A
40
US
Low oxalate fixed diets pre-colonization, Moderately high oxalate fixed diets pre-colonization, Colonization with Oxalobacter formigenes, Low oxalate fixed diets post-colonization, Moderately high oxalate fixed diets post-colonization
University of Alabama at Birmingham, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria
12/30
12/31
NCT06331546: Gut Oxalate Absorption in Calcium Oxalate Stone Disease

Recruiting
N/A
80
US
Low-oxalate diet, High-oxalate diet, soluble oxalate gut absorption test
University of Alabama at Birmingham, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Oxaluria, Healthy
12/30
12/31
SWAT, NCT06588101: Clinical Trial Recruitment and Retention Strategies for Family Members in the ICU

Recruiting
N/A
160
Canada
Written informed consent with infographic, Compensation
Lady Davis Institute, Canadian Institutes of Health Research (CIHR)
Family Members, Recruitment, Clinical Study, Retention, Recruitment of Participants, Study Enrollment, Retention of Participants, Compensation Incentives
04/26
12/26
NCT06431386: Behavioural Activation Therapy and Esketamine for Resistant Depression

Recruiting
N/A
40
Canada
Behavioural Activation (BA) Therapy, Esketamine
The Royal's Institute of Mental Health Research
Depressive Disorder, Treatment-Resistant, Depressive Disorder, Major, Bipolar Disorder
08/26
08/26
FACS, NCT04716036: Familial Risk for Bipolar Disorder and Alcohol Sensitivity

Completed
N/A
68
US
Alcohol beverage, Placebo beverage
University of Texas at Austin
Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
06/24
06/24
NCT04279483: GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments

Completed
N/A
336
US
Tobacco retailer, Non-tobacco retailer
Abramson Cancer Center at Penn Medicine, National Cancer Institute (NCI), New York University, Stanford University
Smoking, Tobacco, Smoking, Smoking, Cigarette
06/24
06/24
NCT05884437: The Effects of Chiropractic in Adults With Metabolic Syndrome

Suspended
N/A
10
US
Chiropractic adjustment
Life University
Metabolic Syndrome
07/25
12/25
NCT06385392: Continuous Wearable Monitor for the Detection and Release of Freezing of Gait.

Completed
N/A
31
US
Haptic module and insole device
HealthPartners Institute
Parkinson Disease
04/25
04/25
I-YMSC, NCT06657950: Treatments for Improving Mood in Women Survivors of Interpersonal Violence: A Community-Engaged Study-1.2

Completed
N/A
11
US
Integrative hatha yoga and mindful self-compassion
Butler Hospital, National Center for Complementary and Integrative Health (NCCIH)
Distress
05/25
05/25
NCT06172660: Real-World Effectiveness of Perinatal RSV Immunoprophylaxis

Recruiting
N/A
3750
US
Nirsevimab, RSV vaccines
Yale University, National Institute of Allergy and Infectious Diseases (NIAID)
RSV Infection
12/28
12/28
DETECT-POAF, NCT06519747: DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery

Recruiting
N/A
750
Canada
Cardiac monitoring device
Population Health Research Institute
Atrial Fibrillation, Atrial Flutter
08/26
12/26
SiESTa 2, NCT06336590: Student Exercise and Sleep Timing Study - Part 2

Recruiting
N/A
62
US
Morning Exercise
Rutgers, The State University of New Jersey
Sleep, Mood, Stress
12/26
12/26
NCT03556683: Phase I Assessment of Hypertonic Saline in Moderate to Severe Asthmatics

Completed
N/A
22
US
3% Hypertonic Saline, 7% Hypertonic Saline
University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI)
Moderate to Severe Asthma
06/24
06/24
NCT06907888: Rhythm Express Wearable System vs. Simultaneous Polysomnography for the Diagnosis of Obstructive Sleep Apnea in Adults With Suspected or Observed Atrial Fibrillation

Recruiting
N/A
30
US
Rhythm Express Wearable System
VivaQuant
Obstructive Sleep Apnea (OSA), Atrial Fibrillation (Paroxysmal), Palpitations
05/25
05/25
CoMind EFS, NCT06368648: CoMind Early Feasibility Study

Recruiting
N/A
581
US
CoMind Technologies Limited, Lindus Health
Intracranial Pressure, Intracranial Pressure Changes, Traumatic Brain Injury, Intracerebral Hemorrhage, Encephalitis, Encephalopathy, Hydrocephalus, Stroke, Autoregulation
10/25
10/25
NCT05006404: Autus Valve Pivotal Study

Recruiting
N/A
50
US
Pulmonary Valve Replacement Surgery
Autus Valve Technologies, Inc.
Congenital Heart Disease
08/26
02/36
URBI, NCT06560021: Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

Enrolling by invitation
N/A
1642
US
Biopsy strategy
University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
12/28
06/29
MASTR, NCT05243966: Myriad™ Augmented Soft Tissue Reconstruction Registry

Recruiting
N/A
800
US
Myriad Matrix™ and Myriad Morcells™
Aroa Biosurgery Limited
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus, Anal Fistula, Hidradenitis Suppurativa, Pressure Injury
01/28
01/29
NCT06770998: A Study of a Novel EEG Neurofeedback System for PTSD Treatment

Not yet recruiting
N/A
250
US
EEG-neurofeedback training, Prism training, amyg-EFP training, active Prism training, Sham training, sham Prism training
Foundation for Atlanta Veterans Education and Research, Inc., GrayMatters Health Ltd., Rochester Institute of Technology, New York University Grossman School of Medicine, Atlanta VA Medical Center, Birmingham VA Health Care System, Ralph H. Johnson VA Medical Center, VA Boston Healthcare System, CTP Inc, BioStats Statistical Consulting Ltd, ShareCRF, United States Department of Defense
Stress Disorders, Post-Traumatic
06/27
08/27
THRIVE, NCT06843213: Teaching Harm Reduction in a Hospital Setting: A Peer-led Intervention

Recruiting
N/A
390
US
Peer Intervention, Enhanced Usual Care
University of Pennsylvania, National Institute on Drug Abuse (NIDA), University of Pittsburgh
Opioid Use Disorder, Harm Reduction
08/27
12/28
MOUD+, NCT06837662: The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients with Opioid Use Disorder Seen in Primary Care

Not yet recruiting
N/A
70
US
MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), collaborative care, integrated behavioral health, MOUD Plus, Treatment As Usual (primary care with low threshold MOUD prescribing), usual care, treatment as usual, low-threshold MOUD prescribing
Oregon Health and Science University, National Institute on Drug Abuse (NIDA), Central City Concern
Opioid Dependence, Substance Abuse Disorders, Complex Medical Patients, Primary Care Patients with Chronic Conditions
03/26
11/26
FASTR-TEN, NCT06867185: Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries

Recruiting
N/A
60
US
Brief Electrical Stimulation Therapy, BES, Therapeutic Electrical Stimulation, Electrical Stimulation, Digital Nerve Repair, Nerve Repair
Checkpoint Surgical Inc.
Digital Nerve Injury, Nerve Injury, Nerve Reconstruction, Nerve Trauma, Digital Nerve Lesion
12/26
03/27
NCT06989320: Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

Recruiting
N/A
80
US
Low-oxalate diet and glycolate dosing, Oral glycolate dosing, Oral 13C- ascorbic acid dosing
University of Alabama at Birmingham, University of Texas, Southwestern Medical Center at Dallas, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Kidney Stones, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate, Nephrolithiasis, Nephrolithiasis, Calcium Oxalate, Oxalate Urolithiasis, Healthy, Healthy Volunteer
12/30
12/31
SARE-A, NCT05738837: An Evaluation of a Sexual Assault Resistance Program for Adolescent Girls

Recruiting
N/A
900
Canada
A-EAAA Sexual Assault Resistance Education Program immediately, Girls -- Flip the Script with EAAA, Usual care + A-EAAA at 6 months
University of Windsor, Public Health Agency of Canada (PHAC)
Sexual Assault
12/25
12/25
NCT06999330: TMS in Anxiety-Parkinson's Disease

Not yet recruiting
N/A
15
US
Theta burst stimulation active coil, Transmagnetic stimulation, MagVenture, Sham coil
HealthPartners Institute
Parkinsons Disease (PD), Anxiety
12/27
03/28
NCT06880731: Training Inner Speech in Children With Developmental Language Disorder

Recruiting
N/A
75
US
Modeling with Verbal Mediation, Modeling Only
MGH Institute of Health Professions, National Institute on Deafness and Other Communication Disorders (NIDCD)
Developmental Language Disorder
03/28
03/28
NCT05984680: COPD Care Pathway Among Patients With Cancer

Recruiting
N/A
100
US
Observational Phase 1, Observational Phase 2, Group I, Observational Phase 2, Group II, Observational Phase 3
Wake Forest University Health Sciences, National Cancer Institute (NCI), National Center for Advancing Translational Sciences (NCATS)
Chronic Obstructive Pulmonary Disease, Lung Cancer, Head and Neck Cancer
03/26
03/26
NCT05893927: Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes

Recruiting
N/A
120
US
Diabetes education web site application
The Reading Hospital and Medical Center, Reading Hospital Foundation, Complete Statistical Services (Consult-Stat)
Diabetes Mellitus, Type 2, Diabetes Education, Lifestyle Modification
09/25
09/25
PHONES, NCT04662320: Promoting Healing of Nerves Through Electrical Stimulation

Active, not recruiting
N/A
100
US
Checkpoint BEST System, Brief Electrical Stimulation (BES) Therapy
Checkpoint Surgical Inc., Congressionally Directed Medical Research Programs
Cubital Tunnel Syndrome, Nerve Compression, Nerve Injury, Ulnar Neuropathies
12/25
12/25
 

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