Azienda ospedaliero universitaria consorziale policlinico - bari
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 10 Trials 
24 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Grignani, Giovanni
METROPHOLYS, NCT04656262 / 2018-001075-20: Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients

Terminated
3
79
Europe
Cyclophosphamide, Endoxan, Doxorubicin
Istituto Oncologico Veneto IRCCS, Ministry of Health, Italy
Soft Tissue Sarcoma Adult
05/24
05/24
FIBROSARC, NCT04650984 / 2016-003239-38: A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma

Recruiting
3
102
Europe
Onfekafusp alfa, L19TNF, Doxorubicin
Philogen S.p.A.
Soft Tissue Sarcoma
12/25
12/25
STRASS 2, NCT04031677: Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

Recruiting
3
250
Europe, Canada, Japan, US, RoW
Surgery, Preoperative chemotherapy, neoadjuvant chemotherapy
European Organisation for Research and Treatment of Cancer - EORTC, Canadian Cancer Trials Group, ECOG-ACRIN Cancer Research Group, Anticancer Fund, Belgium, Australia and New Zealand Sarcoma Association, Japan Clinical Oncology Group
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
04/27
04/28
REGISTRI, NCT02638766 / 2015-001048-12: Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST

Completed
2
15
Europe
regorafenib, Stivarga
Grupo Espanol de Investigacion en Sarcomas, Bayer
Gastrointestinal Stromal Tumors
08/21
08/21
FLASH, NCT04733183 / 2018-004104-19: Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma

Active, not recruiting
2
98
Europe
Dacarbazine, DTIC, onfekafusp alfa, L19TNF
Philogen S.p.A., Philogen S.p.A.,
Soft Tissue Sarcoma
12/25
12/25
ChonDRAgon, NCT04950075: Study of INBRX-109 in Conventional Chondrosarcoma

Recruiting
2
201
Europe, US, RoW
INBRX-109, Placebo
Inhibrx Biosciences, Inc
Conventional Chondrosarcoma
09/25
12/26
ERASING, NCT03840772 / 2018-004571-12: Eribulin in Advanced Solitary Fibrous Tumor

Completed
2
16
Europe
Eribulin, Intervention under investigation
Italian Sarcoma Group, Eisai Inc.
Solitary Fibrous Tumor
09/24
09/24
ISG-MCS, NCT04305548 / 2019-003733-41: Study on Trabectedin in Advanced Rearranged Mesenchymal Chondrosarcoma

Recruiting
2
16
Europe
Trabectedin
Italian Sarcoma Group, PharmaMar
Mesenchymal Chondrosarcoma
08/25
12/25
TOMAS2, NCT03838744 / 2018-004497-10: Randomized Trial in Advanced, Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.

Completed
2
130
Europe
Standard arm: Trabectedin in monotherapy, Trabectedin arm, Experimental arm: Trabectedin + Olaparib, Trabectedin+ Olaparib arm
Italian Sarcoma Group, PharmaMar, AstraZeneca
Advanced Soft Tissue Sarcoma
11/24
11/24
ImmunoSarc, NCT03277924 / 2016-004040-10: Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas

Completed
1/2
197
Europe
Sunitinib 37.5 MG, Sunitinib 25 MG [Sutent], Sutent, Nivolumab 100 MG/10 ML [Opdivo], Opdivo, Epirubicin, Ifosfamide, Doxorubicin, Dacarbazine, Cisplatin, Methotrexate
Grupo Espanol de Investigacion en Sarcomas
Soft Tissue Sarcoma, Bone Sarcoma
06/24
06/24
TRASTS, NCT02275286: Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients

Recruiting
1/2
199
Europe
Trabectedin, Yondelis, Radiotherapy
Grupo Espanol de Investigacion en Sarcomas, Centre Leon Berard, Italian Sarcoma Group
Liposarcoma, Myxoid, Sarcoma, Soft Tissue, Leiomyosarcoma, Liposarcoma, Pleomorphic Liposarcoma
06/28
06/28
Breast-Sarc, NCT04749446: Study on Clinical Features and Outcomes of Breast Sarcoma

Recruiting
N/A
300
Europe
Treatment of Breast Sarcoma according clinical practice (includes drugs, surgery or any other received treatments)
Italian Sarcoma Group
Breast Sarcoma
12/25
12/25
NCT02829437: Observational Study on Endometrial Stromal Tumors

Recruiting
N/A
100
Europe
Treatment for EST
Italian Sarcoma Group
Endometrial Stromal Tumors
12/25
12/25
EPISObs, NCT03099681: An Observational Study on Epithelioid Sarcoma

Recruiting
N/A
100
Europe
Treatment for Epitheloid Sarcoma
Italian Sarcoma Group
Epithelioid Sarcoma
11/25
12/25
Metabol-Sarc, NCT04735289: Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma

Recruiting
N/A
810
Europe
EPIC-COS Food Frequency Questionnaire diet Evaluation, EPIC-FFQ diet Evaluation, Metabolome, Microbiota, Lymphocytes subpopulations
Istituto Ortopedico Rizzoli, International Agency for Research on Cancer
Osteosarcoma, Ewing Sarcoma
12/24
12/24
ISG-Os2Oss, NCT04890067: Observational Study in Localized Osteosarcoma

Recruiting
N/A
120
Europe
Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group, Associazione Italiana Ematologia Oncologia Pediatrica
Localized Osteosarcoma
06/26
12/26
EWOss, NCT04845893: Observational Study on Skeletal Ewing's Sarcoma

Recruiting
N/A
100
Europe
Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group
Ewing Sarcoma of Bone
05/28
05/28
Mascarin, Maurizio
RADIOPED, NCT06639165: Retrospective-perspective Observational Cohort Study on Toxicity and Efficacy of Radiotherapy in Pediatric and Adult Patients With Pediatric Histology Treated at the Pediatric Radiotherapy of the CRO in Aviano

Recruiting
N/A
280
Europe
Centro di Riferimento Oncologico - Aviano
Radiation Toxicity
09/30
09/30
NCT06229535: The Right to be Forgotten in the AYA Population: Patients' Experience and Perspectives (Diritto All'Oblio)

Recruiting
N/A
60
Europe
Centro di Riferimento Oncologico - Aviano
Oncologic Disorders
11/24
11/24
SPIDER-MEN, NCT06830356: Somatostatin Receptor PET Imaging to Guide Radiotherapy Dose Escalation in High Risk Meningiomas.

Recruiting
N/A
53
Europe
Dose escalation of radiation therapy, based on somatostatin receptor PET imaging
Centro di Riferimento Oncologico - Aviano
Meningioma
12/37
12/37
ISG-Os2Oss, NCT04890067: Observational Study in Localized Osteosarcoma

Recruiting
N/A
120
Europe
Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group, Associazione Italiana Ematologia Oncologia Pediatrica
Localized Osteosarcoma
06/26
12/26
EWOss, NCT04845893: Observational Study on Skeletal Ewing's Sarcoma

Recruiting
N/A
100
Europe
Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group
Ewing Sarcoma of Bone
05/28
05/28
Leonardis, Francesco De
ISG-Os2Oss, NCT04890067: Observational Study in Localized Osteosarcoma

Recruiting
N/A
120
Europe
Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group, Associazione Italiana Ematologia Oncologia Pediatrica
Localized Osteosarcoma
06/26
12/26
EWOss, NCT04845893: Observational Study on Skeletal Ewing's Sarcoma

Recruiting
N/A
100
Europe
Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group
Ewing Sarcoma of Bone
05/28
05/28
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Grignani, Giovanni
METROPHOLYS, NCT04656262 / 2018-001075-20: Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients

Terminated
3
79
Europe
Cyclophosphamide, Endoxan, Doxorubicin
Istituto Oncologico Veneto IRCCS, Ministry of Health, Italy
Soft Tissue Sarcoma Adult
05/24
05/24
FIBROSARC, NCT04650984 / 2016-003239-38: A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma

Recruiting
3
102
Europe
Onfekafusp alfa, L19TNF, Doxorubicin
Philogen S.p.A.
Soft Tissue Sarcoma
12/25
12/25
STRASS 2, NCT04031677: Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

Recruiting
3
250
Europe, Canada, Japan, US, RoW
Surgery, Preoperative chemotherapy, neoadjuvant chemotherapy
European Organisation for Research and Treatment of Cancer - EORTC, Canadian Cancer Trials Group, ECOG-ACRIN Cancer Research Group, Anticancer Fund, Belgium, Australia and New Zealand Sarcoma Association, Japan Clinical Oncology Group
Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
04/27
04/28
REGISTRI, NCT02638766 / 2015-001048-12: Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST

Completed
2
15
Europe
regorafenib, Stivarga
Grupo Espanol de Investigacion en Sarcomas, Bayer
Gastrointestinal Stromal Tumors
08/21
08/21
FLASH, NCT04733183 / 2018-004104-19: Efficacy and Safety of L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma

Active, not recruiting
2
98
Europe
Dacarbazine, DTIC, onfekafusp alfa, L19TNF
Philogen S.p.A., Philogen S.p.A.,
Soft Tissue Sarcoma
12/25
12/25
ChonDRAgon, NCT04950075: Study of INBRX-109 in Conventional Chondrosarcoma

Recruiting
2
201
Europe, US, RoW
INBRX-109, Placebo
Inhibrx Biosciences, Inc
Conventional Chondrosarcoma
09/25
12/26
ERASING, NCT03840772 / 2018-004571-12: Eribulin in Advanced Solitary Fibrous Tumor

Completed
2
16
Europe
Eribulin, Intervention under investigation
Italian Sarcoma Group, Eisai Inc.
Solitary Fibrous Tumor
09/24
09/24
ISG-MCS, NCT04305548 / 2019-003733-41: Study on Trabectedin in Advanced Rearranged Mesenchymal Chondrosarcoma

Recruiting
2
16
Europe
Trabectedin
Italian Sarcoma Group, PharmaMar
Mesenchymal Chondrosarcoma
08/25
12/25
TOMAS2, NCT03838744 / 2018-004497-10: Randomized Trial in Advanced, Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.

Completed
2
130
Europe
Standard arm: Trabectedin in monotherapy, Trabectedin arm, Experimental arm: Trabectedin + Olaparib, Trabectedin+ Olaparib arm
Italian Sarcoma Group, PharmaMar, AstraZeneca
Advanced Soft Tissue Sarcoma
11/24
11/24
ImmunoSarc, NCT03277924 / 2016-004040-10: Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas

Completed
1/2
197
Europe
Sunitinib 37.5 MG, Sunitinib 25 MG [Sutent], Sutent, Nivolumab 100 MG/10 ML [Opdivo], Opdivo, Epirubicin, Ifosfamide, Doxorubicin, Dacarbazine, Cisplatin, Methotrexate
Grupo Espanol de Investigacion en Sarcomas
Soft Tissue Sarcoma, Bone Sarcoma
06/24
06/24
TRASTS, NCT02275286: Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients

Recruiting
1/2
199
Europe
Trabectedin, Yondelis, Radiotherapy
Grupo Espanol de Investigacion en Sarcomas, Centre Leon Berard, Italian Sarcoma Group
Liposarcoma, Myxoid, Sarcoma, Soft Tissue, Leiomyosarcoma, Liposarcoma, Pleomorphic Liposarcoma
06/28
06/28
Breast-Sarc, NCT04749446: Study on Clinical Features and Outcomes of Breast Sarcoma

Recruiting
N/A
300
Europe
Treatment of Breast Sarcoma according clinical practice (includes drugs, surgery or any other received treatments)
Italian Sarcoma Group
Breast Sarcoma
12/25
12/25
NCT02829437: Observational Study on Endometrial Stromal Tumors

Recruiting
N/A
100
Europe
Treatment for EST
Italian Sarcoma Group
Endometrial Stromal Tumors
12/25
12/25
EPISObs, NCT03099681: An Observational Study on Epithelioid Sarcoma

Recruiting
N/A
100
Europe
Treatment for Epitheloid Sarcoma
Italian Sarcoma Group
Epithelioid Sarcoma
11/25
12/25
Metabol-Sarc, NCT04735289: Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma

Recruiting
N/A
810
Europe
EPIC-COS Food Frequency Questionnaire diet Evaluation, EPIC-FFQ diet Evaluation, Metabolome, Microbiota, Lymphocytes subpopulations
Istituto Ortopedico Rizzoli, International Agency for Research on Cancer
Osteosarcoma, Ewing Sarcoma
12/24
12/24
ISG-Os2Oss, NCT04890067: Observational Study in Localized Osteosarcoma

Recruiting
N/A
120
Europe
Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group, Associazione Italiana Ematologia Oncologia Pediatrica
Localized Osteosarcoma
06/26
12/26
EWOss, NCT04845893: Observational Study on Skeletal Ewing's Sarcoma

Recruiting
N/A
100
Europe
Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group
Ewing Sarcoma of Bone
05/28
05/28
Mascarin, Maurizio
RADIOPED, NCT06639165: Retrospective-perspective Observational Cohort Study on Toxicity and Efficacy of Radiotherapy in Pediatric and Adult Patients With Pediatric Histology Treated at the Pediatric Radiotherapy of the CRO in Aviano

Recruiting
N/A
280
Europe
Centro di Riferimento Oncologico - Aviano
Radiation Toxicity
09/30
09/30
NCT06229535: The Right to be Forgotten in the AYA Population: Patients' Experience and Perspectives (Diritto All'Oblio)

Recruiting
N/A
60
Europe
Centro di Riferimento Oncologico - Aviano
Oncologic Disorders
11/24
11/24
SPIDER-MEN, NCT06830356: Somatostatin Receptor PET Imaging to Guide Radiotherapy Dose Escalation in High Risk Meningiomas.

Recruiting
N/A
53
Europe
Dose escalation of radiation therapy, based on somatostatin receptor PET imaging
Centro di Riferimento Oncologico - Aviano
Meningioma
12/37
12/37
ISG-Os2Oss, NCT04890067: Observational Study in Localized Osteosarcoma

Recruiting
N/A
120
Europe
Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group, Associazione Italiana Ematologia Oncologia Pediatrica
Localized Osteosarcoma
06/26
12/26
EWOss, NCT04845893: Observational Study on Skeletal Ewing's Sarcoma

Recruiting
N/A
100
Europe
Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group
Ewing Sarcoma of Bone
05/28
05/28
Leonardis, Francesco De
ISG-Os2Oss, NCT04890067: Observational Study in Localized Osteosarcoma

Recruiting
N/A
120
Europe
Treatment of Osteosarcoma according the AIEOP/ISG OS 2021 recommendations (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group, Associazione Italiana Ematologia Oncologia Pediatrica
Localized Osteosarcoma
06/26
12/26
EWOss, NCT04845893: Observational Study on Skeletal Ewing's Sarcoma

Recruiting
N/A
100
Europe
Treatment of Ewings Sarcoma of bone according clinical practice (includes drugs, surgery, radiotherapy or any other received treatments)
Italian Sarcoma Group
Ewing Sarcoma of Bone
05/28
05/28

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