| Heart and Blood Diseases |
ACTRN12621001604897p: Carotid Stenosis Management During the COVID-19 Era
with Best Medical Intervention Alone (CASCOM Study)
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| Not yet recruiting | 4 | 1543 | | | Monash University | Stroke prevention (ischaemic and haemorrhagic stroke); Arterial disease complication prevention; Carotid stenosis; Atherosclerosis; Carotid artery stenting; Carotid endarterectomy; Medical intervention; Non-stroke arterial disease complications | | | | |
ACTRN12621001604897: Carotid Stenosis Management During the COVID-19 Era
with Best Medical Intervention Alone (CASCOM Study)
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| Not yet recruiting | 4 | 1543 | | | Monash University | Stroke prevention (ischaemic and haemorrhagic stroke), Arterial disease complication prevention, Carotid stenosis, Atherosclerosis, Carotid artery stenting, Carotid endarterectomy, Medical intervention, Non-stroke arterial disease complications | | | | |
2004-004404-21: Omega-3-Polyunsaturated Fatty Acids and Atherosclerosis in Systemic Lupus Erythematosus: Cellular Mechanisms and Functional Consequences |
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| Ongoing | 4 | 60 | Europe | Omacor, Capsule, soft, Omacor | GreenPark Healthcare Trust, Queens University Belfast | Systemic Lupus Erythematosus | | | | |
2004-003595-11: clinical trial metoprolol vs. placebo in patients about to undergo in non cardiac surgery and have moderate or high risk of perioperative cardiac effects (PeriOperative ISchemic Evaluation study) Ensayo clínico de metoprolol vs placebo en pacientes que van a ser sometidos a cirugía no cardiaca y que estén en riesgo moderado o alto de sufrir eventos cardíacos perioperatorios (PeriOperative ISchemic Evaluation study) |
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| Ongoing | 4 | 10000 | Europe | Betaloc IV INJ 1 MG/ML, TOPROL-XL Tab 200 MG, 00719846, Injection*, Tablet, Betaloc IV INJ 1 MG/ML, TOPROL-XL Tab 200 MG | Canadian Cardiovascular Collaboration, Population Health Research Institute, McMaster University, Asociación Colaboración Cochrane Iberoamericana (ACCIb), , Asociación Colaboración Cochrane Iberoamericana (ACCIb) | Perioperative cardiac events frequently complicate non-cardiac surgery resulting in significant morbidity, mortality and cost. There is no clear evidence from RCTs on how to lower perioperative cardiac risk.This a multi-centre, double-blind, randomized controlled group trial of metoprolol vs placebo in 10,000 moderate and high risk patients undergoing non-cardiac surgery., patients with moderate or high cardiovascular risk (atherosclerotic disease, coronary disease) undergoing in non cardiac surgery Pacientes con moderado a alto riesgo cardiovascular que son sometidos a cirugía no cardiaca, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR-TRC-07000015: Randomized Study on DK Crush Technique Versus Provisional Stenting Technique for Coronary Artery Bifurcation Lesions |
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| Completed | 4 | 370 | | Use DK Crush Technique; Use Provisional Stenting Technique | The First Affiliated Hospital, Nanjing Medical University; Jiwei Medical Manufacturing Company, Jiwei Medical Manufacturing Company, Ltd. | Coronary atherosclerotic heart disease | | | | |
ChiCTR-OCH-11001602: Relationship between peripheral micro-RNAs and the severity and prognosis of coronary atherosclerosis |
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| Completed | 4 | | | | Zhongshan Hospital, Fudan University; Level of the institution：, China National Funds for Distinguished Young Scientis(30725036) | Coronary artery disease | | | | |
ChiCTR-ONRC-12002035: Effects of intensive treatment of Statin Towards atherosclerosis plaques in patients with borderline vulnerable plaque lesion |
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| Completed | 4 | 64 | | atorvastatin intensive treatment | Shanghai Pu Dong GongLi Hospital Department of Cardiology; Shanghai Pu Dong Gong Li Hospital, Shanghai pudong new area health system the leader in the field of training plan PWRd 2011-04 and Shanghai pudong new area health system in key discipline construction plan PWZxk2010-05 | Coronary heart disease | | | | |
2012-000152-34: valuation of the effect of a new drug for diabetes on atherosclerosis in patients with primary failure metformin valutazione dell'effetto di un nuovo farmaco per il diabete sull'aterosclerosi in pazienti in fallimento primario con metformina |
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| Ongoing | 4 | 64 | Europe | Film-coated tablet, JANUVIA*28CPR RIV 100MG | AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA, azienda policlinico umberto I | Type 2 diabetes Diabete mellito tipo 2, Type 2 diabetes Diabete tipo 2, Diseases [C] - Hormonal diseases [C19] | | | | |
| Completed | 4 | 100 | | Clopidogrel Hydrogensulfate Tablets ;none | Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine; Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine, scientic fund of department | coronary atherosclerotic heart disease | | | | |
ChiCTR-TRC-11001677: Effect of pharmaceutical care intervention on medication compliance, treatment outcome and carotid atherosclerotic plaques in patients with hyperlipidemia. |
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| Completed | 4 | 100 | | traditional therapy ;Patient specific intervention (pharmaceutical care) | Suzhou Municipal Hospital; Suzhou Science and Technology Bureau, research projects of Suzhou Science and Technology Bureau | hyperlipidemia | | | | |
ChiCTR-TRC-10000919: Study of Beraprost sodium Tables combination with Aspirin for prevention of type 2 diabetes patients’ atherosclerosis progress |
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| Completed | 4 | 200 | | Beraprost sodium Tables combination with Aspirin ;Aspirin | China-Japan Friendship Hospital; Astellas Pharma China, Astellas Pharma China, Inc. | Arteriosclerosis | | | | |
ChiCTR-TRC-10001085: Effect of Rosuvastatin on Coronary Atheroma in diffused Coronary Artery Disease |
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| Completed | 4 | 400 | | Rosuvastatin ;Atorvastatin | Second affiliated Hospital of Third Military Medical University; Second affiliated Hospital of Third Military Medical University, Second affiliated Hospital of Third Military Medical University | Diffused Coronary Artery Disease | | | | |
ChiCTR-TRC-13003477: Clinical evaluation of contrast medium and cardiac function in the patients with cardio-renal syndrome by minimally-invasive hemodynamic monitoring method |
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| Completed | 4 | 90 | | give iso-osmolar contrast medium (Iodixanol) ;give low-osmolar contrast medium (Iopromide) | Chinese People's Liberation Army General Hospital; Chinese People's Liberation Army General Hospital, GE (Shanghai) Ltd. Company | coronary atherosclerotic heart disease | | | | |
2013-002437-37: Effects on intravascular attenuation of coronary arteries using low iodine concentrated contrast media while maintaining identical amount of iodine administered to patient per second |
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| Ongoing | 4 | 390 | Europe | Solution for injection, Ultravist 240, Ultravist 300, Ultravist 370 | Maastricht University Medical Centre, Maastricht University Medical Centre | atypical or typical complaints of angina pectoris with no previous cardiovascular medical historylow to intermediate risk for atherosclerosis referred for coronary CTA to rule out CAD, coronary artery problem without previous heart-vessel medical historyheart vessels hardening referred for coronary CTA to rule out the coronary artery disease, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Investigative Techniques [E05] | | | | |
| Completed | 4 | 1200 | | Placebo capsule with the same appearance of Tongxinluo capsule, made by Yiling Pharmaceutical Co., China, will be given orally after meals, 6 capsules each time, twice daily. ;Tongxinluo capsule, made by Yiling Pharmaceutical Co., China, will be given orally after meals, 6 capsules each time, twice daily. | Shandong University Qilu Hospital; Ministry of Health of P.R. China, Key Project of clinical speciality of Ministry of Health | atherosclerosis | | | | |
ChiCTR-TRC-13003691: Berberine Chloride Stabilizes Coronary Atherosclerotic Plaques in Clinical Research |
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| Completed | 4 | 120 | | Rosuvastatin+Berberine ;Rosuvastatin | Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Traditional Chinese Medicine Development of the Three-year Action Plan | coronary heart disease | | | | |
ChiCTR-ONC-14004265: A study to evaluate the effect of intensive statin on subclinical atherosclerosis lesions by intravascular ultrasound |
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| Completed | 4 | 30 | | rosuvastatin 20mg | Cardiovascular Department, Beijing Friendship Hospital; Beijing Friendship Hospital, Capital clinical characteristic applied research | acute coronary syndrome | | | | |
2005-000551-15: Effect of folic acid supplementation and allopurinol on endothelial function in patients with rheumatoid arthritis treated with methotrexate |
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| Ongoing | 4 | 80 | Europe | Allopurinol, Folic acid, Allopurinol, Folic acid, | University of Dundee | Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory polyarthritis associated with excess cardiovascular (CV) mortality. Hyperhomocysteinaemia is recognized as an independent CV risk factor and homocysteine levels are frequently elevated in RA patients.Endothelial dysfunction is considered a marker of early atherosclerotic disease and seems to correlate well with future increase CV risk. RA patients are known to have endothelial dysfunction. | | | | |
2005-004080-28: Efficacy and Safety of Niaspan in South Asian Stroke Survivors: NIASTAR TRIAL(Niaspan: Indo-Asian Stroke patienT Atherosclerotic Regression trial) |
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| Ongoing | 4 | 280 | Europe | Niaspan, Simvastatin, Niaspan, Simvastatin, Niaspan, Simvastatin | Sandwell Medical Research Unit | 1. Patients diagnosed as having a stroke based on the WHO CriteriaPatients with transient ischaemic attacks will be included if symptoms of motor or sensory loss were demonstrable with full recovery within 24 hours. Only strokes and TIA that are ischaemic in nature (thrombo-embolic) will be included in the study | | | | |
2006-001574-24: Visualisation of coronary arteries for the analysis of premature atherosclerosis in patients with adult-onset GH deficiency |
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| Ongoing | 4 | 30 | Europe | genotropin, RVG 15790 or RVG 25480, Genotropin, Genotropin | Radboud University Nijmegen Medical Centre, Department of Endocrinology | Patients with adult-onset growth hormone deficiency and the presence of atherosclerotic disease in the coronary arteries | | | | |
2006-001430-40: Tiral of Invasive versus Medical therapy of Early coronary artery disease in Diabetes (TIME-DM) |
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| Ongoing | 4 | | Europe | Aspirin N 100mg, Sortis 40mg, Dilatrend, Aspirin 100mg,, Sortis 40mg, Dilatrend, Aspirin 100mg, | University Hospital Department of Cardiology | The prevalence of type II diabetes is increasing rapidly, contributing importantly to a new \"epidemic\" of coronary artery disease (CAD). Atherosclerosis accounts for 65-80% of all death among diabetic patients, a rate 2-to 4-fold higher than in non-diabetics. Furthermore, diabetic patients often have silent CAD . | | | | |
| Ongoing | 4 | 51 | Europe | adenosine triphosphate, adenosine, rvg 16617, adenocor, adenocor | RUNMC | atherosclerosis | | | | |
2008-002169-30: A randomised placebo-controlled trial of metformin on progression of carotid atherosclerosis in non-diabetic patients with cardiovascular disease treated with conventional risk reducing agents |
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| Ongoing | 4 | 220 | Europe | Glucophage 850mg film-coated tablet (metformin hydrochloride), Glucophage 850mg film-coated tablet (metformin hydrochloride) | Greater Glasgow Health Board, Research and Development Department, Senior Contracts Manager,Research and Enterprise,University of Glasgow | Participants must have definite coronary heart disease: either a previous myocardial infarction or positive findings on coronary angiogram. They can have normal glucose tolerance, impaired fasting glycaemia or impaired glucose tolerance but must not be diabetic. Participants will also be overweight as defined by a waist circumference >80cm in women and >94cm in men. | | | | |
2008-005147-42: Arteriosclerosis y Lupus Eritematoso Sistémico: ¿Pueden las Estatinas detener este proceso? |
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| Ongoing | 4 | 125 | Europe | Fluvastatina, | Mª Angeles Aguirre Zamorano | Prevención primaria del desarrollo de arteriosclerosis precoz en pacientes con Lupus Eritematoso Sistémico. | | | | |
2009-011397-14: Effect of anti-TNF-alpha therapy on endothelial progenitor cells and endothelial dysfunction in patients with psoriasis without risk factors for atherosclerosis |
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| Ongoing | 4 | 20 | Europe | enbrel, Enbrel, Enbrel | Technical University of Dresden | Psoriasis vulgaris | | | | |
2011-000328-13: Ensayo clínico exploratorio del efecto de atorvastatina en la modulación de la rigidez arterial y de los marcadores biológicos implicados en la arteriosclerosis en pacientes con lupus eritematoso sistémico (LES) |
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| Ongoing | 4 | 40 | Europe | Atorvastatina, ATOR, | Dr. Miguel Yebra Bango | LUPUS ERITEMATOSO SISTÉMICO (LES) | | | | |
2013-001948-60: The importance of vitamin D after a meal on inflammation and vascular function in women with vitamin D deficiency and overweight Het belang van vitamine D na de maaltijd op ontstekingsfactoren en vaatfunctie bij vrouwen met vitamine D tekort en overgewicht |
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| Ongoing | 4 | 24 | Europe | Cholecalciferol, Cholecalciferol, Cholecalciferol | Sint Franciscus Gasthuis Rotterdam, Sint Franciscus Gasthuis | \'healthy volunteers\' \'atherosclerosis\' \'vitamin D deficiency\' \'gezonde vrijwilligers\' \'atherosclerose\' \'vitamine D deficientie\' | | | | |
ChiCTR-DPR-15006890: Evaluation of Stent Patients by Coronary CT angIography with iodixAnoL 270mg I/ml (ESPECIAL270) |
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| Unknown status | 4 | | | | Beijing anzhen hospital, capital medical university; Beijing Anzhen hospital, , GE Pharmaceutical company offer | Coronary atherosclerosis | | | | |
ChiCTR-IPR-16008415: Effects of dexmedetomidine upon postoperative delirium in elderly patients undergoing off-pump coronary artery bypass grafting |
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| Recruiting | 4 | 40 | | dexmedetomidine ;Without dexmedetomidine | The First Affiliated Hospital, College of Medicine, Zhejiang University; The First Affiliated Hospital， College of Medicine， Zhejiang University, Department of Education of Zhejiang Province | Coronary atherosclerotic heart disease | | | | |
ChiCTR-DPD-15007510: Coronary computed tomographic angiography at low concentration of contrast media and low tube voltage in obese patients |
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| Unknown status | 4 | | | | Ningbo First Hospital; Ningbo First Hospital, Ningbo Social Developmental Research Project | Coronary atherosclerosis | | | | |
ChiCTR-IPR-15005761: The effects and mechanism of statins on Glucose metabolism in elderly patients with atherosclerotic cardiovascular disease |
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| Recruiting | 4 | 300 | | Atorvastatin calcium ;Atorvastatin calcium ;Rosuvastatin calcium ;Rosuvastatin calcium ;Pitavastatin calcium ;Pitavastatin calcium | Second Department of Cadre Ward, General Hospital of Jinan Military Region; General Hospital of Jinan Military Region, PLA GeneralLogistics Department of the Ministry of health care of special research projects(14BJZ27) | atherosclerotic cardiovascular disease | | | | |
ChiCTR-IPR-15006008: Effect of Exenatide on Carotid Intima-media Thickness and the Biomarkers of Atherosclerosis Compared with Insulin in Patients with Type 2 Diabetes |
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| Not yet recruiting | 4 | 66 | | Exenatide ;insulin | Beijing Hospital, Ministry of Health; Beijing Hospital, Ministry of Health, AstraZeneca Investment (China) Co., Ltd | Type 2 diabetes | | | | |
| Ongoing | 4 | 350 | RoW | Rosuvastatin Krka, Tablet, Rosuvastatin Krka | Icelandic Heart Association, Icelandic Heart Association | Atherosclerosis, Subclinical atherosclerosis of the carotid arteries, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2017-002096-26: Investigate the differences between treating Chronic Kidney Disease - Mineral and Bone Disorder with an iron-containing phosphate binder or a calcium-containing phosphate binder in patients with Kidney Disease treated with dialysis . Monitorering af forskelle ved behandling af Chronic Kidney Disease - Mineral and Bone Disorder med en jernholdig fosfatbinder sammenlignet med en calciumholdig fosfatbinder ved patienter med kronisk nyresygdom behandlet med dialyse. |
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| Ongoing | 4 | 35 | Europe | Velphoro, Sodium Fluoride F 18/ 18F-NaF, Chewable tablet, Solution for injection, Velphoro | Universitetsklinik for Nyresygdomme og Blodtryksforhøjelse, Regionshospitalet Holstebro; Hospitalsenheden Vest, Universitetsklinik for Nyresygdomme og Blodtryksforhøjelse, Regionshospitalet Holstebro; Hospitalsenheden Vest | Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD), especially bone metabolism and blood vessel calcification Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD) med særligt fokus på knoglemetabolismen og åreforkalkning, Examination of the disturbances of bone metabolism and increased risk of atherosclerosis in renal disease patients. Undersøgelse af de forstyrrelser i knoglemetabolismen og øget risiko for åreforkalkning der ses hos nyresyge patienter, Diseases [C] - Nutritional and Metabolic Diseases [C18] | | | | |
2017-002095-10: Investigate the differences between treating Chronic Kidney Disease - Mineral and Bone Disorder with an iron-containing phosphate binder or a calcium-containing phosphate binder in patients with Kidney Disease. Monitorering af forskelle ved behandling af Chronic Kidney Disease - Mineral and Bone Disorder med en jernholdig fosfatbinder sammenlignet med en calciumholdig fosfatbinder ved patienter med kronisk nyresygdom. |
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| Ongoing | 4 | 35 | Europe | Velphoro, Sodium Fluoride F 18/ 18F-NaF, Chewable tablet, Solution for injection, Velphoro | Universitetsklinik for Nyresygdomme og Blodtryksforhøjelse, Regionshospitalet Holstebro; Hospitalsenheden Vest, Universitetsklinik for Nyresygdomme og Blodtryksforhøjelse, Regionshospitalet Holstebro; Hospitalsenheden Vest | Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD), especially bone metabolism and blood vessel calcification Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD) med særligt fokus på knoglemetabolismen og åreforkalkning, Examination of the disturbances of bone metabolism and increased risk of atherosclerosis in renal disease patients. Undersøgelse af de forstyrrelser i knoglemetabolismen og øget risiko for åreforkalkning der ses hos nyresyge patienter, Diseases [C] - Nutritional and Metabolic Diseases [C18] | | | | |
ChiCTR1800015658: Effect of Exenatide on Carotid Intima-media Thickness and the Biomarkers of Atherosclerosis Compared with Insulin in Patients with Type 2 Diabetes |
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| Recruiting | 4 | 66 | | Exenatide 10ugBid ;Aspart 30 insulin | Beijing Hospital; Beijing Hospital, AstraZeneca Investment (China) Co., Ltd. | Atherosclerosis | | | | |
ChiCTR-OPC-16008544: Efficacy of Batroxobin injection in patients with carotid atherosclerosis plaque |
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| Recruiting | 4 | 80 | | batroxobin injection ;non-batroxobin injection | Zhujiang Hospital of Southern Medical University; Zhujiang Hospital of Southern Medical University, Self-financing | carotid atherosclerosis plaque | | | | |
ChiCTR-OPC-16009540: Pharmacoeconomics of rosuvastatin in improving intracranial hemodynamics in patients with intracranial atherosclerotic stenosis, a case records based study |
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| Recruiting | 4 | 50 | | intensified dose of rosuvastatin (20 mg/day, 52 weeks) versus standard dose of rosuvastatin (10 mg/day, 52 weeks) | The Second Affiliated hospital of Zhejiang University School of Medicine; The Second Affiliated hospital of Zhejiang University School of Medicine, self-funding | Intracranial atherosclerotic stenosis | | | | |
2017-002898-19: There is no English name for the trial. IndiviStat#1-tutkimus: Perinnöllisten ja muiden yksilötekijöiden vaikutus statiinilääkehoitoon |
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| Ongoing | 4 | 500 | Europe | Tablet, The products to be administered as IMPs are defined as belonging to an ATC group | Helsinki University Central Hospital, European Research Council, European Commission | Primary prevention of atherosclerotic disease, Primary prevention of atherosclerotic disease, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR-OPN-17012942: The effect of berberine hydrochloride on the treatment of dyslipidemia with atherosclerosis |
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| Recruiting | 4 | 40 | | none ;Treated with berberine | The First Hospital of Jilin University; The First Hospital of Jilin University, CAMS Innovation Fund for Medical Sciences (Nos.2016-I2M-3-011 & 2016-I2M-1-011); NSFC of China (No.81573493); Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study (Z141102004414062) | Dyslipidemia with atherosclerosis | | | | |
| Ongoing | 4 | 1806 | Europe | Capsule, Tablet, , Brilique, Aspirin, Clopidogrel | University Medical Center Utrecht, Antonius fund, Stichting Lijf en Leven, Dutch endovascular alliance, UMCU Vascular surgery fund | It is known that the atherothrombotic cardiovascular adverse event rate in patients with peripheral artery disease (PAD) is high. Also patency rates after (endo)vascular interventions in PAD patients are lower than in other arterial segments. In PAD patients the main focus in studies is on the technical aspects and success, while less attention has been paid to antiplatelet management, despite its significant effect on morbidity and mortality risk. perifeer vaatlijden, Peripheral arterial disease typically strikes arteries of the legs. Arteriosclerosis narrows arteries thereby decreasing the amount of blood and oxygen flowing to the tissues., Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR1800019353: Study for the Bidirectional immune regulation mechanism on preventing and curing atherosclerosis of Shenqimaixintong Capsule based on the tlr sigaling pathway. |
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| Recruiting | 4 | 90 | | SQMXTJN Capsule ;Atorvastatin | Guangzhou Traditional and West Medicine Integrated Hospital; Guangzhou Traditional and West Medicine Integrated Hospital, Traditional Chinese Medicine Bureau of Guangdong Province | Atherosclerosis | | | | |
ChiCTR1800015104: Study on individualized antithrombotic therapy for high-risk groups-A feasibility study on the clinical prognosis of patients with coronary heart disease and diabetes mellitus |
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| Recruiting | 4 | 300 | | Aspirin + clopidogrel ;aspirin + tiglielot | Department of Cardiology;The Second Affiliated Hospital of Army Medical University; Xinqiao Hospital, National key research and development plan | Coronary atherosclerotic heart disease | | | | |
2017-005033-22: How does changing antiretroviral therapy effect the progression of coronary atherosclerosis. |
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| Not yet recruiting | 4 | 100 | Europe | Bictravy, EU/1/18//1289/001, Film-coated tablet, Bictravy | University of Liverpool, Gilead Pharmaceuticals, | Human immunodeficiency virus (HIV) and cardiovascular disease (CVD), Human immunodeficiency virus (HIV) and cardiovascular disease (CVD), Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Recruiting | 4 | 876 | | ginkgolide injection + oral aspirin ;oral aspirin | Huashan Hospital, Fudan University; Huashan Hospital, Ginkgolide Pharmarcal Co.Ltd | Stroke | | | | |
ChiCTR-OPN-17012503: The efficacy and safety of new oral anticoagulant on patients with symptomatic intracranial atherosclerotic stenosis |
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| Recruiting | 4 | 600 | | basic treatment and new oral anticoagulant therapy; basic treatment and customary antiplatelet therapy | Shengjing Hospital of China Medical University; Shengjing Hospital of China Medical University, Self-raised funds | symptomatic intracranial atherosclerotic stenosis | | | | |
2019-001912-50: Effect of Intensive cholesterol-lowering medication on blood flow in the coronary arteries in patients with coronary artery disease. |
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| Not yet recruiting | 4 | 120 | Europe | Tablet, Ezetimibe, Atorvastatin, Rosuvastatin | Department of Cardiology, Aarhus University Hospital, Denmark, Novo Nordisk Foundation, HeartFlow, Department of Cardiology, Aarhus University Hospital, Aarhus | Patients with ischemic heart disease and significant, flow-limiting atherosclerosis in the coronary arteries, Coronary artery disease - also called coronary heart disease., Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR-IIR-17013505: A randomized controlled trial of ind0bufen versus asPirin aftercoronary drug-eluting stentimplantaTION: The OPTION trial |
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| Recruiting | 4 | 4460 | | Indobufen: 100mg/bid +Clopidogrel: 75mg/qd ;Aspirin: 75mg/qd+Clopidogrel: 75mg/qd | Zhongshan Hospital affiliated to Fudan University; Zhongshan Hospital affiliated to Fudan University, None | Coronary atherosclerotic heart disease | | | | |
ChiCTR1800016710: Clinical study on the combination of Chinese and western medicine and intervention strategy to alleviate pain in patients with lower limb arteriosclerosis occlusion |
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| Recruiting | 4 | 90 | | Flurbiprofen injection for treatment ;Flurbiprofen injection treatment + auricular sticking pressure ;Flurbiprofen injection treatment + air wave pressure treatment | the First Affiliated Hospital of Guangxi Medical University; the First Affiliated Hospital of Guangxi Medical University, Guangxi health and Family Planning Commission 研究疾病： 肝癌合并肝硬化 | lower extremity atherosclerotic occlusive disease | | | | |
ChiCTR1900020572: A randomized, double-blind, double-simulated, positive parallel controlled, multicenter clinical trial for ginkgo ketoester drop pills in the treatment of cerebral arteriosclerosis induced vertigo (blood stasis syndrome) |
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| Recruiting | 4 | 404 | | During the experiment, it is forbidden to add any Chinese and western medicine with the same efficacy as the experimental medicine and any medicine that affects the safety evaluation of this medicine. | Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine; Zhejiangjiuxu Pharmaceutical.Co., Ltd, At his own expense | Vertigo due to cerebral arteriosclerosis (blood stasis syndrome) | | | | |
ChiCTR-IIR-17013393: A randomized, open-label, Parallel control clinical trial to evaluate the anti-atherosclerosis efficacy of Qishen capsule combined with atorvastatin on patients with chest pain (Qi deficiency and blood stasis type) (Pre-trial) |
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| Recruiting | 4 | 60 | | Qishen capsule + atorvastatin ;atorvastatin | Department of pharmacy, Anzhen Hospital of Capital Medical University; Henan Xinyi Pharmaceutical Co. Ltd., The national science and technology major drug discovery project & Henan Xinyi Pharmaceutical Co. Ltd. | chest pain (Qi deficiency and blood stasis type) | | | | |
ChiCTR1800017922: Effects of Febuxostat on improving glucose and lipid metabolic, and anti-arteriosclerosis in asymptomatic hyperuricemia patients |
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| Recruiting | 4 | 300 | | Only have low purine diet ;take febuxostat orally | The Affiliated Huai'an 1st People's Hospital of Nanjing Medical University; The Affiliated Huai'an 1st People 's Hospital of Nanjing Medical University, Enterprises aid research | Asymptomatic hyperuricemia | | | | |
| Not yet recruiting | 4 | 44 | Europe | Rosuvastatin, Film-coated tablet, Crestor | Centro Hospitalar e Universitário de Coimbra, E.P.E., Astrazeneca-Produtos Farmacêuticos, Lda | Atherosclerosis, namely in the aorta, carotid and coronary arteries, Cardiovascular disease, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2019-004078-24: Effect of Sarilumab on atherosclerotic disease in Rheumatoid Arthritis Efecto de Sarilumab sobre la enfermedad aterosclerótica en artritis reumatoide |
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| Not yet recruiting | 4 | 20 | Europe | Solution for injection, KEVZARA | IDIVAL, NOT APPLICABLE | RHEUMATOID ARTHRITIS ARTRITIS REUMATOIDE, RHEUMATOID ARTHRITIS ARTRITIS REUMATOIDE, Diseases [C] - Skin and Connective Tissue Diseases [C17] | | | | |
| Not yet recruiting | 4 | 100 | | Patiens will be given Brilinta ;Patients will be given TaiYi. | Tianjin Union Medical Center; Tianjin Union Medical Center, self-raised funds | acute coronary syndrome | | | | |
ChiCTR1800018742: A Randomized Controlled Trial for Efficacy and Safety of berberine on vasculopathy in patients with NSTE-ACS after stenting |
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| Recruiting | 4 | 200 | | The routine therapy ;The routine therapy with berberine 0.4g po t.i.d | The First Affiliated Hospital of Henan University of CM; The First Affiliated Hospital of Henan University of CM, The First Affiliated Hospital of Henan University of CM | coronary atherosclerotic heart disease | | | | |
ChiCTR1900021855: Evaluation of clinical effect of Mailuo Shutong pill on carotid arteriosclerosis and vulnerable plaque with wet and hot stasis |
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| Not yet recruiting | 4 | 240 | | Mailuo Shutong pill ;Comfort Agent | First Affiliated Hospital of Anhui University of Traditional Chinese Medicine; First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Corporate Sponsorship | Carotid arteriosclerosis accompanied by fragile plaque | | | | |
ChiCTR1900021365: Non-inferior-effect single-centered, prospective, randomized controlled trial for Dengzhan Shengmai capsule and aspirin in the treatment of carotid atherosclerosis |
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| Completed | 4 | 116 | | Dengzhan Shengmai capsule ;Aspirin | Department of Vascular Surgery, Changzheng Hospital, the Second Military Medical University; Level of the institution：, Leading talent fund | Carotid atherosclerosis | | | | |
| Recruiting | 4 | 36 | Europe | Metformin / alogliptin Oral Product, Metformin / Pioglitazone Pill, triple therapy | University of Catanzaro | Diabetes Mellitus, Type 2 | 09/20 | 06/21 | | |
2020-001053-44: Stabilization of atherosclerosis in carotid artery by Rivaroxaban as evaluated by 3D ultrasound with contrast |
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| Not yet recruiting | 4 | 62 | Europe | Film-coated tablet, Xarelto® | Rigshospitalet, Department of Vascular Surgery, Bayer AG | Patients with - Stable peripheral artery diseaseand- Asymptomatic, atherosclerotic plaque/stenosis in the carotid artery; asymptomatic regarding cerebral ischaemia including stroke and transient ischaemic attack (TIA) or amaurosis fugax. Patienter med - Stabil perifer arteriel sygdomog - Asymptomatisk, aterosklerotisk plaque/stenose in carotis; asymptomatisk vedr. iskæmisk apopleksi inkluderende stroke og transient cerebral iskæmi (TCI) eller amaurosis fugax., Patients with: - Atherosclerosis in limb arteries and - Atherosclerosis in carotid artery with no symptoms of major or minor stroke or temporary vision loss. Patienter med:- Åreforkalkning i underekstremitets blodkarog- Åreforkalkning i halspulsåren uden symptomer på slagtilfælde eller forbigående synstab., Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Completed | 4 | 105 | Europe | Evolocumab Prefilled Syringe, Placebos | University of Erlangen-Nürnberg Medical School | Atherosclerotic Cardiovascular Disease | 04/21 | 07/21 | | |
NXT-ASSESS, ChiCTR1800019496: A study for exploring the efficacy of Naoxintong Capsules in the treatment of coronary atherosclerotic Plaque on the basis of optimal medical therapy (Aspirin, Statins, Clopidogrel, etc.): Stage One |
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| Not yet recruiting | 4 | 80 | | Naoxintong Capsule ;Placebo | Buchang Pharmaceuticals; FuWai Hospital Chinese Academy of Medical Sciences, Buchang Pharmaceuticals | Atherosclerotic Cardiovascular Disease | | | | |
NCT03403556: High-intensity Rosuvastatin vs. Moderate-intensity Rosuvastatin/Ezetimibe in High Atherosclerotic Cardiovascular Disease Risk Patients With Type 2 Diabetes |
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| Recruiting | 4 | 140 | RoW | Rosuvamibe, Monorova | Yuhan Corporation | Atherosclerotic Cardiovascular Disease, Type 2 Diabetes | 10/21 | 12/21 | | |
2020-000656-35: The effect of colchicine in patients with atherosclerosis of the heart vessels on white blood cells stimulated with crystals |
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| Not yet recruiting | 4 | 20 | Europe | Tablet, Colchicine 0.5mg Tiofarma | Radboud University Medical Centre, Radboud University Medical Centre | Atherosclerosis, Calcifications of the arteries, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR2100042290: Efficacy of Butylphthalide combined with ticagrelor on transient ischemic attack of atherosclerotic origin or minor stroke |
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| Recruiting | 4 | 200 | | Butylphthalide combined with Ticagrelor ;placebo combined with Ticagrelor | Heze Municipal Hospital; Heze Municipal Hospital, self-raised | Transient ischemic attack or minor stroke | | | | |
ChiCTR2000029838: The effect of berberine hydrochloride on apolipoprotein A1, serum inflammatory factors, carotid atherosclerosis and clinical prognosis of patients with stroke |
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| Recruiting | 4 | 280 | | extended release nifedipine tablets+Vitamin B6+Vitamin B12+folic acid/berberine/berberine+folic acid ;Atorvastatin+Aspirin/Aspirin+berberine ;Atorvastatin+Aspirin/Aspirin+berberine | The First Central Hospital of Baoding; Baoding 1st Central Hospital, Baoding Science Technology Projects (No. 1951ZF064); CAMS Innovation Fund for Medical Sciences (No. 2016-I2M-1-011) | Carotid Atherosclerosis，Middle Cerebral Artery Stenosis， Homocysteine | | | | |
| Recruiting | 4 | 90 | Japan | continuous glucose monitoring (CGM) | National Cerebral and Cardiovascular Center | Coronary Atherosclerosis | 12/21 | 03/22 | | |
ChiCTR1900022321: Efficacy and safety of tirofiban in bridging treatment of acute intracranial atherosclerotic vascular occlusion: a randomized controlled trial |
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| Not yet recruiting | 4 | 168 | | tirofiban hydrochloride injection ;Placebo injection | Shanghai General Hospital; Shanghai General Hospital, Shanghai General Hospital Clinical Research Innovation team Project (CTCCR-2018BP05) | acute intracranial atherosclerotic vascular occlusion | | | | |
ChiCTR2100051805: Clinical Study on Atherosclerotic Cardiovascular Disease with Integrated Traditional Chinese and Western Medicine |
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| Recruiting | 4 | 120 | | Huoxin pill | Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of TCM, Shanghai Municipal Health Commission key scientific research project | arteriosclerotic cardiovascular disease | | | | |
| Recruiting | 4 | 450 | RoW | Colchicine, BMS+Colchicine | Centro de estudios en Cardiologia Intervencionista | Coronary Artery Disease, Restenosis of Coronary Artery Stent, Atherosclerosis, Acute Coronary Syndrome | 12/21 | 12/21 | | |
NCT04146155: Efficacy and Safety of Liraglutide in Type 2 Diabetes With Lower Extremity Arterial Disease |
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| Recruiting | 4 | 200 | RoW | Liraglutide+standard-of-care treatment, Victoza, standard-of-care treatment | Second Affiliated Hospital, School of Medicine, Zhejiang University | Type 2 Diabetes, Peripheral Vascular Disorder Due to Diabetes Mellitus | 12/21 | 12/21 | | |
NCT05105750: A Comparative Study of Indobufen and Aspirin in Patients With Coronary Atherosclerosis |
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| Recruiting | 4 | 60 | RoW | aspirin 100 mg/d, indobufen 200 mg bid | The First Affiliated Hospital with Nanjing Medical University | Coronary Atherosclerosis | 03/22 | 03/22 | | |
| Active, not recruiting | 4 | 120 | Europe, RoW | Chocolate PTA Balloon, conventional balloon angioplasty | Klinikum Rosenheim, Medtronic, Herz-Zentrums Bad Krozingen, University Hospital Tuebingen, Klinikum Karlsbad-Langensteinbach, Elblandklinikum Radebeul Interdisziplinäres Gefäßzentrum Radebeul / Riesa, LKH-Universitätsklinikum Graz Univ. Klinik für Innere Medizin Klin. Abteilung für Angiologie, Hanusch-Krankenhaus Kardiovaskuläres Zentrum, Auckland City Hospital, SCO:SSiS, coreLab Black Forest GmbH, Charite University, Berlin, Germany | Atherosclerosis | 03/22 | 03/22 | | |
SLICE-CEA, NCT04539223: A Study of Evolocumab on Carotid Artery Atherosclerotic Plaque Morphology Prior to Carotid EndArterectomy |
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| Recruiting | 4 | 60 | Canada | Evolocumab | Canadian Medical and Surgical Knowledge Translation Research Group, Amgen | Carotid Artery Stenosis, Asymptomatic Carotid Artery Stenosis | 04/22 | 05/22 | | |
ChiCTR2100050965: Clinical study of ginkgo diterpene lactone glumine injection in the treatment of arteriosclerosis small cerebral vascular disease: a single center, self-controlled study |
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| Recruiting | 4 | 30 | | Ginkgo diterpene lactone meglumine injection | The Third Affiliated Hospital of Sun Yat-Sen University; The Third Affiliated Hospital of Sun Yat-Sen University, The Key Areas R&D Program of Science and Technology Program of Guangzhou (202007030010) | cerebral small vessel disease (CSVD) | | | | |
ChiCTR2000031935: The safety and efficacy of tirofiban prior to stenting for intracranial atherosclerotic stenosis |
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| Not yet recruiting | 4 | 180 | | give tirofiban ;not give tirofiban | The First Affiliated Hospital of Shandong First Medical University; The First Affiliated Hospital of Shandong First Medical University, self-collected | intracranial atherosclerotic disease | | | | |
| Completed | 4 | 38 | Europe | Bydureon, Exenatide, Humulin kwickpen, Insulin Aspart, Metformin, Biguanide | Karolinska Institutet | Atherosclerosis, Diabetes, Restenosis | 08/22 | 10/22 | | |
ChiCTR2100049216: Clinical study of multi-target regimen in the treatment of arteriosclerotic cerebral small vessel disease: a single-center, self-controlled study |
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| Recruiting | 4 | 30 | | Ginkgo bilobalide + Lipoic acid + Coenzyme Q + Mecobalt + Idibenone | The Third Affiliated Hospital, Sun Yat-Sen University; The Third Affiliated Hospital, Sun Yat-Sen University, The Key Areas R&D Program of Science and Technology Program of Guangzhou (202007030010) | cerebral small vessel disease | | | | |
2022-002269-14: Research with gallium dotatate PET/CT scans to image atherosclerosis in the coronary arteries. |
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| Ongoing | 4 | 40 | Europe | 68Ga-Dotatate, Solution for injection/infusion, SomaKit TOC | AMC, Cardiovascular Sciences, AMC | Inflammatory atherosclerosis of the coronary arteries., Inflammatory atherosclerosis of the coronary arteries., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Diagnosis [E01] | | | | |
ATLAS Study, ChiCTR1900021393: Antiplatelet therapy for prevention of atherosclerosis in chronic kidney disease: A perspective, multi-center randomized controlled trial |
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| Not yet recruiting | 4 | 554 | | Aspirin ;Blank control | The Second Affiliated Hospital of the Amy Medical University; Sichuan Provincial People's Hospital, The training program for clinical medical research of the army military medical university | chronic kidney diseases | | | | |
2020-005663-31: CARotid plaqUe StabilizatiOn and regression with evolocumab stabilizzazione morfologica e regressione della placca carotidea con evolocumab |
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| Not yet recruiting | 4 | 100 | Europe | REPATHA, [044317030], Solution for injection in pre-filled syringe, REPATHA - 140 MG- SOLUZIONE INIETTABILE- USO SOTTOCUTANEO- SIRINGA PRERIEMPITA (VETRO) (SURECLICK) 1 ML- 1 PENNA PRERIEMPITA | AZIENDA OSPEDALIERA ORDINE MAURIZIANO DI TORINO | atherosclerosis desead MALATTIA ATEROSCLEROTICA, atherosclerosis desead MALATTIA ATEROSCLEROTICA, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Recruiting | 4 | 150 | Europe | Estradiol, Placebo | Hanna Savolainen-Peltonen, University of Southern California | Menopause, Atherosclerosis, Cardiovascular Diseases, Estrogen Replacement Therapy | 12/22 | 12/22 | | |
ChiCTR2100054991: Safety and efficacy of alfentanil in interventional surgery for lower extremity arteriosclerosis obliterans |
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| Recruiting | 4 | 120 | | Induction: Alfentanil 10 μg + Propofol 2 mg/kg; Maintenance: Alfentanil 30 μg/kg/h + Propofol 2-4 mg/kg/h ;Induction: Fentanyl 1.5 μg/kg + Propofol 2 mg/kg; Maintenance: Fentanyl 4.5 μg/kg/h + Propofol 2-4 mg/kg/h | Affiliated Cardiovascular Hospital of Xiamen University; Affiliated Cardiovascular Hospital of Xiamen University, Yichang Renfu Pharmaceutical Co., Ltd. | lower extremity arteriosclerosis obliterans disease | | | | |
ChiCTR2100054126: The effect of PCSK9 inhibitor on the carotid atherosclerotic plaque in patients with acute coronary syndrome |
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| Recruiting | 4 | 80 | | Statins + Ezetimibe + PCSK9 inhibitor ;Statins + Ezetimibe | the First Affiliated Hospital, Sun Yat-Sen University; The First Affiliated Hospital of Sun Yat-Sen University, Suzhou Industrial Park Xinxin Cardiovascular Health Foundation | Acute coronary syndrome | | | | |
| Terminated | 4 | 39600 | US | Icosapent ethyl, Vascepa | Kaiser Permanente, Amarin Corporation | Covid19, Atherosclerosis, Cardiovascular Diseases, Upper Respiratory Tract Infections | 12/22 | 12/22 | | |
Rosuzet-IVUS, NCT03169985: Usual Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin on Coronary Atherosclerotic Plaque |
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| Active, not recruiting | 4 | 280 | RoW | Rosuvastatin 10 mg plus ezetimibe 10 mg orally once a day, Rosuzet tablet 10/10 mg, Rosuvastatin 20 mg orally once a day, Crestor tablet 10 mg | Samsung Medical Center, Hanmi Pharmaceutical co., ltd. | Coronary Artery Disease | 01/27 | 01/27 | | |
FAoRAS, NCT05173025: Effect of Fimasartan on Extended RAS and Vascular Functions in Patients With Type 2 Diabetes and Hypertension |
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| Recruiting | 4 | 42 | RoW | Fimasartan, Kanarb | Seoul National University Bundang Hospital | Hypertension, Atherosclerosis, Diabetes Mellitus, Type 2, Renin Hypertension | 12/22 | 12/23 | | |
ChiCTR2000036400: A multi-center clinical study of integrated Traditional Chinese and Western medicine in the management of atherosclerotic cardiovascular disease |
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| Not yet recruiting | 4 | 200 | | eliminating sputum and removing stasis simultaneously formula ;placebo | Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of TCM; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of TCM, None | arteriosclerotic cardiovascular disease | | | | |
ChiCTR2200057217: Exploration of lipid-lowering treatment scheme of evolocumab: a randomized, single blind, placebo-controlled prospective clinical study |
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| Not yet recruiting | 4 | 60 | | Oral statins combined with ilozumab administered subcutaneously ;An oral placebo combined with a subcutaneous injection of iloxumab | The Second Affiliated Hospital of Zhengzhou University; The Second Affiliated Hospital of Zhengzhou University, self-raised | Atherosclerotic cardiovascular disease (ASCVD) | | | | |
ChiCTR2200063693: Effect of the glucagon-like peptide-1 receptor agonist on atherosclerosis in patient with impaired glucose tolerance |
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| Not yet recruiting | 4 | 40 | | Intervention to improve life style, including balanced diet (i.e. each person should eat 200g-300g protein, 500g fresh vegetables, 250g Cereals, < 20g vegetable oil, < 6G salt and try to eat less sugar); Regular exercise (i.e. walking for 3 km every day for more than 30 min, at least 5 times a&# ;On the basis of lifestyle improvement intervention, subcutaneous injection of liraglutide / Novolin was given | Qingdao Chengyang District People's Hospital; Chengyang People's Hospital in Qingdao, The Qingdao Medical and health guidance program | impaired glucose tolerance | | | | |
EKSTROM, NCT06342609: Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease |
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| Completed | 4 | 84 | US | Colchicine 0.5 MG, Mitigare, Colcrys | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Coronary Artery Disease | 09/24 | 09/24 | | |
ChiCTR2200058029: Study of PCSK9 inhibitor combined with statin for symptomatic intracranial atherosclerotic stenosis |
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| Not yet recruiting | 4 | 120 | | Evalocumab injection + intensive statin | First Affiliated Hospital of Ji'nan University; First Affiliated Hospital of Ji'nan University, self-funded | symptomatic intracranial atherosclerotic stenosis | | | | |
NCT04643431: Risk Assessment of Carotid Plaques Using 3D Contrast-Enhanced Ultrasound |
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| Active, not recruiting | 4 | 20 | US | Perflutren, SHAPE with Definity | Thomas Jefferson University | Carotid Atherosclerosis | 04/23 | 10/24 | | |
2023-000166-33: Semmelweis Lipid Center for high-risk patients Semmelweis Lipid Centrum magas rizikójú betegeknek |
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| Not yet recruiting | 4 | 200 | Europe | Injection, Leqvio | Semmelweis University, Novartis Hungary Ltd., Ministry of Innovation and Technology | primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia in atherosclerotic cardiovascular disease primer hiperkoleszterinémia (heterozigóta famailiáris és nem-familiáris) vagy kevert diszlipidémia ateroszklerotikus kardiovaszkuláris betegségben, high LDL-cholesterol level magas LDL-koleszterinszint, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
NCT04826354: Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular Disease |
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| Completed | 4 | 582 | RoW | Rosuvastatin and Ezetimibe, Rosuvastatin | Korea University Anam Hospital | Atheroscleroses, Coronary | 05/23 | 06/23 | | |
ChiCTR2100046826: The Effect of DPP-4 Inhibitors on the Recurrent Stroke Prevention: an Observational Study in T2DM Patients with Recent Ischemic Stroke |
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| Recruiting | 4 | 100 | | Nil ;Nil | Shanghai Tenth People's Hospital; Shanghai Tenth People's Hospital, Tongji University SITP Project in 2021 | Stroke of large artery atherosclerosis with diabetes mellitus type 2 | | | | |
ChiCTR2100054694: Evaluation of the clinical efficacy of Guanxinning tablets in the treatment of patients with carotid atherosclerotic plaque |
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| Not yet recruiting | 4 | 60 | | Conventional treatment + Guanxinning tablets ;Conventional treatment | Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine; Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine, Chia Tai Qingchunbao Pharmaceutical Co., Ltd. | Carotid atherosclerotic plaque formation | | | | |
NCT01848171: Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism |
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| Active, not recruiting | 4 | 700 | RoW | L-thyroxine, Euthyrox | Shandong Provincial Hospital | Hypothyroidism, Thyroid Diseases, Endocrine System Diseases | 07/23 | 07/23 | | |
ChiCTR2200062051: Effect of levosimendan on PCI related acute myocardial infarction during perioperative period |
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| Not yet recruiting | 4 | 200 | | Levosimendan (5ml) was dissolved in 45ml of 5% glucose injection. 10ug / kg was injected intravenously before PCI. The injection time was more than 10 minutes, and then micro pumped with 0.1ug/kg/min to 24 hours after operation. ;50ml of 5% glucose injection was given by intravenous injection of 10ug/kg before PCI. The injection time was more than 10 minutes, and then micropumped with 0.1ug/kg/min to 24 hours after operation. | Department of Emergency, Shandong Provincial Hospital ; Shandong Provincial Hospital, Horizontal research | Coronary atherosclerotic heart disease | | | | |
ChiCTR2200062305: Mr-VPD evaluation of PCSK9i in patients with intracranial atherosclerotic stenosis |
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| Recruiting | 4 | 100 | | PCSK9iatorvastatin calcium 20mg/ rosuvastatin calcium 10mg; atorvastatin calcium 20mg/ rosuvastatin calcium 10mg | The Second Affiliated Hospital of the Army Medical University; The Second Affiliated Hospital of the Army Medical University, The patient's normal medical treatment process, examination fees and drug costs shall be borne by themself. | Cerebral vascular disease | | | | |
