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  • ||||||||||  AiTan (rivoceranib) / HLB Bio Group
    Trial completion date, Trial primary completion date:  BIOVAS: BIOmarker Driven Trial of VEGFR2 Inhibitor in Advanced Sarcoma (clinicaltrials.gov) -  Sep 24, 2024   
    P2,  N=30, Recruiting, 
    Trial completion date: May 2024 --> Sep 2027 | Trial primary completion date: Feb 2024 --> Oct 2026
  • ||||||||||  MRI of the prostate gland  () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_418;    
    Radiologists must be aware of these entities and need to be familiar with their key imaging findings. Nevertheless, biopsy is still often required for confirmation, as there is some overlap in imaging findings for some of these diseases.
  • ||||||||||  Renal vasculature imaging () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_411;    
    On the other hand, CT and MR angiography provide superior anatomical detail, not only of the renal vessels but also of adjacent structures, aiding in the comprehensive assessment of these complex conditions. In summary, recognising the imaging characteristics of normal anatomy of renal vasculature and vascular anatomic variants and pathologies that may affect these vessels is essential for guiding appropriate management and ensuring successful outcomes in patients with these conditions.
  • ||||||||||  Primary Retroperitoneal Soft Tissue Tumors: An Imaging Overview () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_399;    
    Recognizing the imaging features of various retroperitoneal masses is essential for precise patient evaluation. In summary, radiology plays a crucial role in diagnosing primary retroperitoneal soft tissue tumors by providing detailed, non-invasive imaging, which supports early and accurate diagnosis, leading to improved patient outcomes and management.
  • ||||||||||  Beyond Renal Cell Carcinoma: Unravelling Uncommon Renal Masses () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_379;    
    Comprehending these lesions' clinical and imaging characteristics is crucial for accurate differential diagnosis and informed post-surgical management recommendations. While renal cell carcinoma remains the primary diagnosis, comprehensive evaluation of imaging patterns within clinical contexts improves diagnostic precision and patient care in radiology practice.
  • ||||||||||  tamoxifen / Generic mfg.
    Sonographic evaluation of pelvic masses () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_373;    
    Risk factors for endometrial cancer include obesity, diabetes, polycystic ovarian syndrome, nulliparity, hypertension, unopposed estrogen replacement therapy, and tamoxifen use...This knowledge not only helps in distinguishing between benign and malignant lesions but also aids in planning appropriate follow-up or treatment. Therefore, radiologists' familiarity with these sonographic features is essential for effective patient care and management, ensuring that any necessary additional testing or interventions are promptly initiated based on the ultrasound findings.
  • ||||||||||  Retroperitoneum and perirenal space: an anatomic and pictorial review () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_371;    
    Conclusions Radiologists play a crucial role in the successful management of patients with retroperitoneal disease by recognising the anatomic relationships, and by describing and interpreting normal and pathologic imaging findings. Knowledge of the anatomy of the retroperitoneum is essential to understand pathological conditions involving it, how they spread locally and to distant locations and to guide clinical evaluation and treatment.
  • ||||||||||  MRI Structured report for endometrial cancer according to new 2023 FIGO staging system () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_367;    
    Conclusions Implementation of MRI structured report in patients with endometrial cancer serves as an aid to clinical practice in a guideline-oriented environment. Radiologists also benefit from MRI templates by reporting all pertinent observation that can potentially influence on the decision-making process in a multidisciplinary oncogynecological team.
  • ||||||||||  multimodality imaging of the urachus: anomalies and complications () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_354;    
    In some cases, the combination of clinic, demographic findings, location and imaging findings help in the differential diagnosis, but sometimes only the histopathological examination allows a definitive diagnosis to be established (1). Patent urachus Urachal cyst Umbilical-urachal sinus Vesicourachal diverticulum Infected umbilical-urachal sinus Infected umbilical-urachal sinus Urachal mucinous adenocarcinoma Urachal mucinous adenocarcinoma Urachal endometrioma Conclusions With the increased use of cross-sectional imaging, it is important for the radiologist to know the normal development and anatomy of the urachus and recognize the characteristic imaging features of urachal anomalies and potential complications, to ensure early detection and optimal management.
  • ||||||||||  progesterone / Generic mfg.
    Oh, it is not a kidney stone! - Hydronephrosis unravelled () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_345;    
    Pregnancy Hydronephrosis is a common finding in pregnant women, as it can be a result of increased workload on the kidneys, progesterone effect on relaxation of smooth muscle cells lining the walls of the urinary pathways and extrinsic compression of the ureters by the gravidic uterus...The ureter crosses significant anatomical landmarks that can be uncommon sources of pathology. Radiologists must consider these when interpreting hydronephrosis across various imaging modalities.
  • ||||||||||  Imaging of female ureteric pathology: where GYN meets GU () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_340;    
    Lack of knowledge of the rarer disease processes may lead to misdiagnosis and ineffective treatment. The purpose of this multicentre educational review is to share our most interesting and challenging cases, to serve as a comprehensive resource for radiologists.
  • ||||||||||  hyoscine butylbromide injection / Generic mfg.
    MRI of the female pelvis: summary of the recommendations of the ESUR female pelvic imaging working group () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_338;    
    The purpose of this multicentre educational review is to share our most interesting and challenging cases, to serve as a comprehensive resource for radiologists. Clinical indications for MRI examination, minimal and optimal MRI acquisition protocols and standardized reporting focused on the following: (a) initial staging, recurrence and follow-up of uterine cervical cancer, (b) initial staging of vulvar cancer, (c) female genital tract congenital anomalies (FGTCAs), (d) initial staging of endometrial cancer, (e) uterine leiomyomas, (f) characterization of sonographically indeterminate adnexal mass, and (g) pelvic endometriosis are presented.Patient preparation for MRI of the female pelvis ?scheduling MRI according to the phases of menstrual cycle: NOT recommended ?clinical questions: should be asked before the exam (e.g., time of menstruation, clinical symptoms, hormonal medication, prior surgical procedures) ?fasting (4-6h) ?patient position: supine ?antiperistaltic agents: 20 mg butyl scopolamine im/iv or 1 mg of glucagon iv, unless contraindicated ?urinary bladder: moderately filled: patients should empty their bladder 1h prior to examination ?vaginal gel: optional in uterine cervical cancer, vulvar cancer, FGTCAs and endometriosis, sonographic gel, self-administration may be recommended, no consensus ?rectal gel: optional in endometriosis ?bowel preparation: advocated as
  • ||||||||||  Renal Transplant Masses () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_331;    
    Perinephric myxoid pseudotumor of fat is a recently described and underrecognized benign inflammatory lesion that may mimic well-differentiated liposarcoma. Infections such as TB may also present with infiltrative soft tissue and inflammatory changes in the renal transplant sinus, mimicking neoplastic conditions such as PTLD.
  • ||||||||||  Decoding the diagnostic complexities of fat-containing renal lesions () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_319;    
    Current literature recommends percutaneous biopsy for differentiating fat-rich AML from fat-containing RCC when CT and MRI are inconclusive, as well as distinguishing fat-invisible AML from non-clear cell RCC due to significant overlap in imaging findings. The diagnostic value of percutaneous biopsy in the differentiation of fat-poor AML from clear-cell RCC remains controversial.
  • ||||||||||  Abdominal wall endometriosis and its mimics - A pictorial review () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_313;    
    Image 1 Image 2 Image 3 Image 4 Image 5 Image 6 Image 7 Image 8 Conclusions Abdominal wall endometriosis can be a difficult conundrum for Radiologists. Desmoids, metastatic deposits, endometrial cancer and sarcoma closely resemble endometriosis and a good knowledge of imaging characteristics with the combination of clinical history can help the radiologist in providing the accurate interpretation of the image findings, further narrowing down the diagnosis and aiding in overall management of the patient.
  • ||||||||||  Magnetic resonance imaging features of uterine smooth muscle tumours of uncertain malignant potential () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_307;    
    Axial T2 (4a), T1 (4b), and T1 fat-saturated (4c) images demonstrating extensive intralesional haemorrhage within a myometrial mass as evidenced by the high signal on all three sequences. Note the T2 intermediate signal thick enhancing peripheral soft tissue component (4a and 4d) showing diffusion restriction seen on the DWI b = 1000 (4e) and ADC (4f) images (arrowheads).
  • ||||||||||  Keys to avoid over or underdiagnosis when using the PI-RADS scoring system () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_300;    
    Radiologists should take into account the histopathological features of these lesions to understand their MRI signals. Correlation of imaging findings with patient history, symptoms, PSA levels, and prior biopsy results is crucial for making an accurate diagnosis and avoiding over-reliance on the PI-RADS score alone.
  • ||||||||||  don't miss the veins! urogenital tumors with intravascular extension: what every radiologist should know. () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_289;    
    Multidisciplinary collaboration between urologists, gynaecologists, vascular and cardiothoracic surgeons in planning for ultra-major surgery and intensive perioperative care in order to achieve best patient outcome. Patient prognostications and imaging follow up surveillance for recurrent aggressive benign AML or malignant vascular tumours are integral to holistic patient care.
  • ||||||||||  Welireg (belzutifan) / Merck (MSD)
    Age Knows No Bounds: Renal Neoplasms Awareness in the Younger Population () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_285;    
    Minimally invasive treatments such as cryoablation and newer targeted therapies like belzutifan are also used to manage smaller tumors and avoid surgery...Medications like mTOR inhibitors (e.g., everolimus) can shrink tumors...A thorough review of medical history, imaging, and genetic background is essential. Radiologists play a key role in identifying familial patterns, which significantly impacts treatment decisions.
  • ||||||||||  Unravelling perirenal space pathologies: a radiological perspective () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_265;    
    Although clinical and imaging findings often lack specificity, adopting a structured approach to imaging can help narrow the differential diagnosis, facilitating more accurate evaluation and guiding appropriate treatment strategies. Understanding the typical patterns of disease spread and the common imaging characteristics within this space is crucial for effective diagnosis and management.
  • ||||||||||  Differential diagnosis of fat-containing renal lesions () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_264;    
    A thorough understanding of the diverse imaging features of fat-containing renal lesions is of paramount importance for radiologists. This knowledge not only facilitates accurate diagnosis but also enables the differentiation of specific lesions, thereby guiding appropriate clinical management strategies.
  • ||||||||||  Spectrum of diseases beyond prostate malignancy on PSMA PET/CT imaging () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_259;    
    PSMA is also expressed in neovascular endothelial cells of non-prostatic tumors and non-neoplastic processes and may falsely interpreted as metastatic/recurrent prostatic adenocarcinoma. . PSMA uptake may be seen in infectious and inflammatory processes, which interfere with the accurate interpretation and staging of prostate cancer.
  • ||||||||||  Perinephric myxoid pseudotumor of fat: imaging features and differential diagnosis () -  Sep 24, 2024 - Abstract #ESUR2024ESUR_257;    
    Figure 9: Differential diagnosis: Abscess, Inflammatory pseudotumor & Extramedullary hematopoiesis. Conclusions The viewers learn the multimodality imaging features of unilateral, bilateral and transplant PNMP and familiarize with the spectrum of benign and malignant clinical entities constituting the differential diagnosis of PNMP.
  • ||||||||||  Review, Journal:  Extra-Acral Minute Synovial Sarcoma: A Case Report With Literature Review. (Pubmed Central) -  Sep 23, 2024   
    Undoubtedly, further studies, utilizing large samples and carried out on different populations, are necessary to confirm these results. The mass was excised and measured 0.6 cm in greatest dimension with histomorphology findings, immunohistochemical and molecular workup confirming the diagnosis of "minute" synovial sarcoma.
  • ||||||||||  Biomarker, Journal:  Identification of ENO-1 positive extracellular vesicles as a circulating biomarker for monitoring of Ewing sarcoma. (Pubmed Central) -  Sep 23, 2024   
    Elevated ENO-1+CD81+ extracellular vesicles in the serum of patients before treatments distinguished patients with Ewing sarcoma from healthy individuals with an area under the curve value of 0.92 (P?<?0.001) and reflected the tumor burden in patients with Ewing sarcoma during multidisciplinary treatments. Collectively, circulating ENO-1+CD81+ extracellular vesicle detection could represent a novel tool for tumor monitoring of Ewing sarcoma.
  • ||||||||||  Journal:  Pancreatic masses in children: a single-center experience over two decades. (Pubmed Central) -  Sep 22, 2024   
    Children with pancreatic tumors amenable to surgical resection appear to have adequate long-term survival. Short-term outcomes at diagnosis are excellent and mainly appear to be influenced by the presence of metastatic disease at initial presentation.