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NCT05179850: Computer Aided Diagnostic Tool on Computed Tomography Images for Diagnosis of Retroperitoneal Tumor in Children |
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| Recruiting | N/A | 400 | RoW | Radiomic Algorithm | West China Hospital | Wilms' Tumor, Neuroblastoma, Teratoma, Lymphoma, Sarcoma, Germ Cell Tumor | 12/23 | 12/23 | | |
NCT04742387: Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis |
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| Active, not recruiting | N/A | 40 | US | | National Cancer Institute (NCI) | Kaposi Sarcoma, KSHV Associated Multicentric Castleman Disease, Primary Effusion Lymphoma, IL-6 Related KSHV Associated Cytokine Syndrome | 12/24 | 12/24 | | |
NCT05038254: Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events |
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| Recruiting | N/A | 750 | US | Best Practice, standard of care, standard therapy, Patient Monitoring, medical monitoring, monitor, Questionnaire Administration | M.D. Anderson Cancer Center | Clinical Stage IV Esophageal Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8, Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8, Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8, Clinical Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage IVB Gastric Cancer AJCC v8, Metastatic Colon Carcinoma, Metastatic Esophageal Carcinoma, Metastatic Gastric Carcinoma, Metastatic Liver Carcinoma, Metastatic Malignant Digestive System Neoplasm, Metastatic Malignant Small Intestinal Neoplasm, Metastatic Malignant Thoracic Neoplasm, Metastatic Pancreatic Carcinoma, Metastatic Rectal Carcinoma, Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IV Esophageal Squamous Cell Carcinoma AJCC v8, Pathologic Stage IV Gastric Cancer AJCC v8, Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8, Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8, Postneoadjuvant Therapy Stage IV Esophageal Adenocarcinoma AJCC v8, Postneoadjuvant Therapy Stage IV Esophageal Squamous Cell Carcinoma AJCC v8, Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8, Postneoadjuvant Therapy Stage IVA Esophageal Adenocarcinoma AJCC v8, Postneoadjuvant Therapy Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8, Postneoadjuvant Therapy Stage IVB Esophageal Adenocarcinoma AJCC v8, Postneoadjuvant Therapy Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8, Stage IV Colon Cancer AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Stage IV Rectal Cancer AJCC v8, Stage IV Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal Gastrointestinal Stromal Tumor AJCC v8, Stage IVA Colon Cancer AJCC v8, Stage IVA Hepatocellular Carcinoma AJCC v8, Stage IVA Rectal Cancer AJCC v8, Stage IVB Colon Cancer AJCC v8, Stage IVB Hepatocellular Carcinoma AJCC v8, Stage IVB Rectal Cancer AJCC v8, Stage IVC Colon Cancer AJCC v8, Stage IVC Rectal Cancer AJCC v8 | 01/26 | 01/26 | | |
NCT04751591: Study On Safety Of Endoscopic Resection For 2-5cm Gastric Gastrointestinal Stromal Tumor |
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| Not yet recruiting | N/A | 260 | NA | Endoscopic resection, Laparoscopic partial gastrectomy | Shanghai Zhongshan Hospital | Gastric GIST | 12/23 | 06/24 | | |
ChiCTR2200058255: Study on precise therapy of imatinib in gastrointestinal stromal tumor based on pharmacogenomics and metabonomics |
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| Not yet recruiting | N/A | 306 | | None | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hospital Pharmacy Talents Special Fund Project of Hospital Pharmacy Committee of China Pharmaceutical Association | Gastrointestinal stromal tumor (GIST) | | | | |
NCT05778955: Study on Dynamic CtDNA Analysis in Pediatric Soft Tissue Sarcoma |
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| Recruiting | N/A | 40 | RoW | detection and monitoring of cirulating tumor DNA | Sun Yat-sen University, Nanjing Geneseeq Technology Inc. | Pediatric Soft Tissue Sarcoma | 12/23 | 12/23 | | |
ChiCTR2200065150: Exploring the correlation among metabolism and transport gene polymorphism of methotrexate and its treatment toxicity |
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| Not yet recruiting | N/A | 300 | | None | The Second Xiangya Hospital of Central South University; The Second Xiangya Hospital, Provincial Health Commission Project | osteosarcoma | | | | |
NCT05963035: Clinical Application of 18F-PFPN PET Imaging in Diagnosis and Staging of Clear Cell Sarcoma of Soft Tissue |
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| Recruiting | N/A | 10 | RoW | 18F-PFPN, 18F-PEG3-FPN | Wuhan Union Hospital, China | Clear Cell Sarcoma of Soft Tissue | 12/23 | 06/24 | | |
ALLUME, NCT04430725: Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, Study |
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| Recruiting | N/A | 120 | US | Computed Tomography with Contrast, Contrast Enhanced Computed Tomography, CONTRAST ENHANCED CT SCAN, Contrast-enhanced Computed Tomography, CT Scan With Contrast, CT with Contrast, Microwave Ablation, Ablation, Microwave, Questionnaire Administration, Wedge Excision, Wedge Resection | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Lung Non-Small Cell Carcinoma, Metastatic Colorectal Carcinoma, Metastatic Sarcoma, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Colorectal Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Colorectal Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Colorectal Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8, Stage IVC Colorectal Cancer AJCC v8 | 01/26 | 01/26 | | |
PIPER, NCT04008238: Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients |
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| Recruiting | N/A | 200 | Europe | Trabectedin | Institut BergoniƩ | Soft Tissue Sarcoma Adult, Undifferentiated Pleomorphic Sarcoma, Epithelioid Sarcoma, Solitary Fibrous Tumors, Hemangioendothelioma, Desmoplastic Round Cell Tumor, Synovial Sarcoma | 01/24 | 01/25 | | |
FURTHER, NCT04307914: Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases |
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| Recruiting | N/A | 216 | Europe | External beam radiotherapy, MR-HIFU, MRgFUS, MR guided High Intensity Focused Ultrasound | UMC Utrecht, Turku University Hospital, UniversitƤtsklinikum Kƶln, University of Roma La Sapienza, Istituto Ortopedico Rizzoli, University of Bologna, Isala | Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer, Pain, Cancer Induced Bone Pain, Quality of Life, Tumor, Neoplasm Metastasis | 01/26 | 06/26 | | |
| Recruiting | N/A | 250 | Europe | vena punction | University Medical Center Groningen, Dutch Cancer Society | Gastro-intestinal Stromal Tumors | 01/24 | 09/24 | | |
NCT05310539: Early Recovery After "Wedge Resection" Surgery to Remove Lung Mestastasis Secondary to Bone Cancer. |
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| Recruiting | N/A | 100 | Europe | assessment of the early recovery after wedge resection surgery | Istituto Ortopedico Rizzoli | Metastasis Lung, Bone Neoplasm | 01/24 | 01/26 | | |
NCT06324916: Donor Site Morbidity After Free Vascularized Fibular Graft |
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| Recruiting | N/A | 20 | RoW | Xray | Assiut University | Osteosarcoma | 01/26 | 12/26 | | |
| Recruiting | N/A | 40 | Canada | Archival tumor tissue collection and blood draws | University Health Network, Toronto, Mount Sinai Hospital, Canada, The Hospital for Sick Children | Soft Tissue Sarcoma | 12/24 | 01/25 | | |
NCT05474794: Detective Flow Imaging Endoscopic Ultrasonography in Subepithelial Lesions |
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| Recruiting | N/A | 30 | RoW | DFI-EUS, CE-EUS | Instituto Ecuatoriano de Enfermedades Digestivas | Leiomyoma, GIST | 01/24 | 06/24 | | |
NCT06243588: Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing Sarcoma |
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| Recruiting | N/A | 400 | Europe | clinical records review | Istituto Ortopedico Rizzoli | Ewing Sarcoma | 07/24 | 07/24 | | |
NCT04072393: Cardiac Rehabilitation for Patients Receiving Radiation Therapy for Thoracic Cancers |
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| Recruiting | N/A | 25 | US | Home-based cardiac rehabilitation | Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital | Lung Cancer, Esophageal Cancer, Thoracic Cancer, Hodgkin Lymphoma, Hodgkin Disease, Non-hodgkin Lymphoma, Sarcoma, Thymoma, Breast Cancer | 03/25 | 03/25 | | |
ChiCTR2100046099: Clinical trial of an umbrella study of precise treatment of bone and soft tissue sarcoma based on molecular pathways |
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| Recruiting | N/A | 51 | | SHR-1701+Famitinib ;Camrelizumab+SHR-6390 ;SHR-2554 | Affiliated Sixth People's Hospital, Shanghai Jiaotong University; Affiliated Sixth People's Hospital, Shanghai Jiaotong University, self-funded | advanced bone and soft tissue sarcoma | | | | |
ChiCTR2000029233: Prostate arterial embolization with drug-eluting microspheres for inoperable prostate sarcoma |
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| Not yet recruiting | N/A | 60 | | HepaSphere was loaded with doxorubicin to embolize tumor blood vessels with a drug-loaded embolization microsphere ;Doxorubicin was slowly perfused through the prostatic artery and then embolized with PVA granules (pva-100) | Department of Interventional Radiology, the First Medical Center, Chinese PLA General Hospital; The First Medical Center, Chinese PLA General Hospital, Self-fund | Prostate sarcoma | | | | |
NCT02701153: Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort |
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| Recruiting | N/A | 51 | US | Conventional Surgery, Hypofractionated Radiation Therapy, Hypofractionated Radiotherapy, hypofractionation, Laboratory Biomarker Analysis, Questionnaire Administration | Jonsson Comprehensive Cancer Center, Radiological Society of North America, Sarcoma Alliance for Research through Collaboration, Sarcoma Foundation of America, Tower Cancer Research Foundation | Recurrent Adult Soft Tissue Sarcoma | 02/25 | 02/26 | | |
NCT03442465: Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas |
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| Recruiting | N/A | 180 | US | Toronto Extremity Salvage Score, TESS, Musculoskeletal Tumor Society Score, MSTS 3, Timed Get Up and Go Test, Orthogonal Radiographs, Radiographic Assessments, Weight Bearing for lower extremities only, Range of Motion | Memorial Sloan Kettering Cancer Center | Bone Sarcoma, Osteosarcoma, Chondrosarcoma, Ewing's Sarcoma, Osseous Sarcoma, Bone Neoplasm | 02/25 | 02/25 | | |
RNASARC, NCT03375437: - Molecular Screening Program of Soft Tissue Sarcomas With Complex Genomic Profile to Detect NTRK1/2/3, ROS1 or ALK Gene Fusions. |
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| Active, not recruiting | N/A | 376 | Europe | Blood and tumor samples | Centre Leon Berard, Hoffmann-La Roche | Soft Tissue Sarcoma, Advanced Cancer, Metastatic Cancer | 02/24 | 01/25 | | |
| Recruiting | N/A | 100 | US | Cross-sectional imaging | Memorial Sloan Kettering Cancer Center | Desmoid Fibromatosis | 02/25 | 02/25 | | |
Cryomics, NCT06224283: Radiomics Compared With Conventional Response Criteria for Predicting Progression of Desmoid Tumor After Cryoablation |
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| Recruiting | N/A | 21 | Europe | Cryoablation | Istituto Ortopedico Rizzoli, University of Sao Paulo | Desmoid | 07/24 | 12/24 | | |
NCT06205745: Quality of Life in Amputated Patients Based on Social Deprivation Factors |
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| Recruiting | N/A | 250 | US | | University of Florida | Amputations for Management of Sarcoma,Trauma,or Chronic Infection | 02/25 | 02/25 | | |
NCT01505569: Auto Transplant for High Risk or Relapsed Solid or CNS Tumors |
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| Completed | N/A | 44 | US | Ifosfamide, Mitoxana, Ifex, Etoposide, Eposin, Etopophos, Vepesid, VP-16, Mesna, Uromitexan, Mesnex, G-CSF, Granulocyte colony-stimulating factor, Busulfan, Busulfex, Melphalan, 50 mg/m2 IV over 30 min, Thiotepa, Thioplex, Autologous stem cell infusion, Radiation, Carboplatin, Paraplatin, Paclitaxel, Taxol, Onxal, Leukapheresis, Anti-seizure prophylaxis, Ursodiol | Masonic Cancer Center, University of Minnesota | Ewing's Family Tumors, Renal Tumors, Hepatoblastoma, Rhabdomyosarcoma, Soft Tissue Sarcoma, Primary Malignant Brain Neoplasms, Retinoblastoma, Medulloblastoma, Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET), Atypical Teratoid/Rhabdoid Tumor (AT/RT), CNS Tumors, Germ Cell Tumors | 02/24 | 02/24 | | |
NCT02734823: Long Term Effects of Tyrosine Kinase Inhibitor Therapy on Ovarian Reserve and Fertility in Patients With Chronic Myeloid Leukemia or Gastrointestinal Stromal Tumor |
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| Withdrawn | N/A | 20 | US | Cytology Specimen Collection Procedure, Cytologic Sampling, Laboratory Biomarker Analysis, Questionnaire Administration, Ultrasonography, ULTRASOUND, Ultrasound Imaging, Ultrasound Test, Ultrasound, Medical, US | University of Southern California, National Cancer Institute (NCI) | Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Gastrointestinal Stromal Tumor, Premenopausal | 03/24 | 03/24 | | |
| Recruiting | N/A | 60 | US | AYA Connect intervention, Positive Psychology (PP) intervention, Positive Psychology Plus (PP+) intervention | UNC Lineberger Comprehensive Cancer Center | Cancer, Physical Activity, Cancer Survivorship, Mental Health, Obesity, Breast Cancer, Breast Neoplasms, Malignant Neoplasm, Hodgkin Lymphoma, Hodgkin Disease, Non Hodgkin Lymphoma, Lymph Node Cancer, Nasopharyngeal Carcinoma, Sarcoma, Ewing Sarcoma, Chondrosarcoma, Osteoid Sarcoma, Myeloma, Leukemia, Bone Tumor, Brain Tumor, Central Nervous System Tumor, Germ Cell Tumor | 11/24 | 11/24 | | |
NCT06387485: A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning |
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| Recruiting | N/A | 150 | US | 3D Printed Anatomic Model, CT/MRI | Ricoh USA, Inc. | Sarcoma, Ewing, Chondrosarcoma, Osteosarcoma, Fibrous Histiocytoma, Fibrosarcoma | 12/24 | 04/25 | | |
NCT06321055: An Observational Study to Learn More About Treatment With Regorafenib in People With Advanced Gastrointestinal Stromal Tumors in the United States |
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| Completed | N/A | 136 | US | Regorafenib (Stivarga, BAY73-4506) | Bayer | Advanced Gastrointestinal Stromal Tumor | 05/24 | 05/24 | | |
| Not yet recruiting | N/A | 400 | US | | BostonGene, Exigent | Breast Cancer, Non-small Cell Lung Cancer, Melanoma, Sarcoma | 01/26 | 01/28 | | |
PIONEER, NCT03896958: The Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) |
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| Recruiting | N/A | 1000 | US | | SpeciCare, Georgia Institute of Technology, Predictive Oncology, University of Washington, Netnoids, Northeast Georgia Hospital System | Cancer, All Types, Cancer of Liver, Cancer of Stomach, Cancer of Head and Neck, Cancer of Rectum, Cancer of Kidney, Cancer of Esophagus, Cancer of Colon, Cancer Skin, Cancer of Cervix, Cancer, Metastatic, Cancer of Larynx, Cancer of Neck, Cancer of Lung, Cancer of Brain and Nervous System, Cancer of Vulva, Disseminated, Cancer of Pancreas, Sarcoma, GIST, Small-cell Lung Cancer, Adenocarcinoma Lung, Cancer of Prostate, Cancer, Advanced, Adrenal Cancer, Testicular Cancer, Uterine Cancer, Bronchoalveolar Cell Lung Cancer, Cancer Unknown Primary, Glioblastoma Multiforme, Oligodendroglioma, Breast Cancer, Renal Cell Carcinoma, Hepatocellular Carcinoma, Cholangiocarcinoma, Squamous Cell Carcinoma, Transitional Cell Carcinoma, Cancer, Other, Cancer, Anal, Melanoma, Cancer, Bile Duct, Cancer, Bladder, Cancer Cords Vocal, Cancers Cell Neuroendocrine, Cancer Differentiated Poorly, Cancer, Anaplastic Thyroid | 03/24 | 03/24 | | |
NCT06409013: Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma |
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| Recruiting | N/A | 50 | US | Non-Interventional Study | Mayo Clinic | Bone Sarcoma, Soft Tissue Sarcoma | 03/27 | 03/27 | | |
| Recruiting | N/A | 10 | US | Questionnaire | Montefiore Medical Center | Osteosarcoma | 12/27 | 12/29 | | |
| Recruiting | N/A | 250 | Europe | Observational | Italian Sarcoma Group | Angiosarcoma | 04/29 | 04/34 | | |
NCT05718778: Piamprilizumab (AK105) Combined With Radiotherapy for Neoadjuvant Treatment of Soft Tissue Sarcoma |
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| Recruiting | N/A | 31 | RoW | Piamprimab (AK105), radiotherapy | Henan Cancer Hospital | Soft Tissue Sarcoma | 03/24 | 03/24 | | |
NCT06115681: Real-world Study of Dedifferentiated Liposarcoma Patients in China |
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| Completed | N/A | 1390 | RoW | | Boehringer Ingelheim | Dedifferentiated Liposarcoma | 05/24 | 05/24 | | |
| Active, not recruiting | N/A | 30 | Canada | Image-guided adjuvant pelvic radiotherapy | Lawson Health Research Institute | Endometrioid Adenocarcinoma, Serous Carcinoma, Clear Cell Carcinoma, Carcinosarcoma, Dedifferentiated Carcinoma | 04/24 | 04/24 | | |
RFAdesmoid, NCT06355921: A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors |
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| Not yet recruiting | N/A | 27 | RoW | radiofrequency ablation | Blokhin's Russian Cancer Research Center | Desmoid Tumor, Desmoid Fibromatosis, Desmoid | 02/26 | 05/28 | | |
NCT06451302: Risk Stratification Oriented Treatment of Pediatric Ewing Sarcoma: a Prospective Multicenter Cohort Study |
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| Active, not recruiting | N/A | 100 | RoW | cyclophosphamide, adriamycin, vincristineļ¼Ifosfamideļ¼etoposide, vinorelbine | Yizhuo Zhang | Ewing Sarcoma, Risk Stratification | 05/27 | 12/27 | | |
NCT06363201: Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours |
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| Not yet recruiting | N/A | 40 | RoW | Ocoxin Oral solution | Catalysis SL | Advanced Cancer, Advanced Solid Tumor, Lymphoma, Hodgkin, Central Nervous System Tumor, Sarcoma, Germ Cell Tumor, Pediatric Cancer | 12/24 | 12/25 | | |
NCT06396962: Survival and Prognostic Factors of Primary Retroperitoneal Sarcomas After Surgery: a Single-center Experience |
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| Completed | N/A | 110 | RoW | WANG DAORONG | Northern Jiangsu People's Hospital | Primary Retroperitoneal Sarcoma | 04/24 | 04/24 | | |
| Recruiting | N/A | 120 | Europe | [18F]-JK-PSMA-7 PET/CT scan | Leiden University Medical Center | Sarcoma,Soft Tissue, Urothelial Carcinoma | 05/24 | 06/24 | | |
NCT06193369: Digital Peer Navigation for Adolescents and Young Adults With Cancer |
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| Not yet recruiting | N/A | 80 | NA | Digital Peer Navigation | University Health Network, Toronto, Canadian Cancer Society (CCS), Young Adult Cancer Canada | Lymphoma, Breast Cancer, Testicular Cancer, Sarcoma | 12/25 | 12/25 | | |
NCT06275854: YASU Research Registry: For Young Adults With Cancer |
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| Not yet recruiting | N/A | 5000 | NA | | Young Adult Survivors United, Staunton Farm Foundation, Elsie H. Hillman Foundation | Cancer, Leukemia, Sarcoma, Germ Cell Cancer, Lymphoma, Colorectal Cancer, Melanoma, Breast Cancer | 05/30 | 05/30 | | |
| Recruiting | N/A | 150 | US | | National Cancer Institute (NCI) | Kaposi Sarcoma, HIV | 12/34 | 12/36 | | |
PROGEN_SARC, NCT06076070: GENomic PROfilation for Therapeutic Purposes in SARComas and Molecular Tumor Board (MTB): Retrospective/Prospective Study in Referral Centers |
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| Recruiting | N/A | 10 | Europe | | Regina Elena Cancer Institute, Candiolo Cancer Institute - IRCCS, Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale, Istituto Oncologico Veneto IRCCS, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Istituto Ortopedico Rizzoli, Ospedale Pediatrico Bambin GesĆ¹, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituti Tumori Giovanni Paolo II, Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori | Sarcoma | 05/24 | 05/24 | | |
ePPS-2202, NCT06211257: Superiority Trial Evaluating Digitalized Information Media for Patients With Advanced Sarcomas Receiving Second Line Treatment. |
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| Recruiting | N/A | 377 | Europe | Dematerialized Personalized Care Plan (ePCP) | Centre Oscar Lambret, CanceropƓle Nord Ouest | Sarcoma Metastatic, Locally Advanced Soft Tissue Sarcoma | 06/26 | 03/28 | | |
NCT03261544: Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method? |
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| Recruiting | N/A | 50 | US | Proximal Femur Replacement | Duke University | Sarcoma, Bone Metastases, Proximal Femur Replacement | 06/24 | 11/26 | | |
| Recruiting | N/A | 100 | Europe | | Centre Leon Berard | Brain Cancer, Meningioma, Sarcoma | 06/24 | 06/24 | | |
NCT06431451: The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients With Advanced GISTs |
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| Not yet recruiting | N/A | 60 | NA | | First Affiliated Hospital, Sun Yat-Sen University | Gastrointestinal Stromal Tumors | 12/25 | 12/25 | | |
NCT05526417: Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma |
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| Recruiting | N/A | 30 | US | Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized Tomography, CT, CT Scan, tomography, Educational Intervention, Education for Intervention, Intervention by Education, Intervention through Education, Intervention, Educational, Magnetic Resonance Imaging, Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, Physical Therapy, Physiatric Procedure, Physical Medicine Procedure, Physical Therapeutics, Physical Therapy Procedure, Physiotherapy, Physiotherapy Procedure, PT, Questionnaire Administration, Telemedicine, Telehealth | Mayo Clinic | Soft Tissue Sarcoma, Stage I Soft Tissue Sarcoma of the Trunk and Extremities, Stage II Soft Tissue Sarcoma of the Trunk and Extremities, Stage III Soft Tissue Sarcoma of the Trunk and Extremities | 06/25 | 06/26 | | |
NCT05049538: Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in High-Risk Endometrial Cancers |
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| Recruiting | N/A | 50 | US | Biospecimen Collection, Biological Sample Collection, Liquid Biopsy, Plasma Biopsy, Pap Smear, Cervical Smear Preparation, Cervical Smear Procedure, Pap Smear Procedure, Pap Test, Papanicolaou Smear Procedure, Papanicolaou Test, Vaginal Smears | M.D. Anderson Cancer Center | Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma, Endometrial Mucinous Adenocarcinoma, Endometrial Serous Adenocarcinoma, Malignant Uterine Neoplasm, Uterine Corpus Carcinosarcoma | 06/24 | 06/24 | | |
HIFU-UPS, NCT04123535: Focused Ultrasound to Promote Immune Responses for Undifferentiated Pleomorphic Sarcoma |
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| Recruiting | N/A | 20 | US | ExAblate 2000/2100 Magnetic Resonance-guided Focused Ultrasound (MRgFUS), ExAblate 2000/2100, MRgFUS | Matthew Bucknor, Focused Ultrasound Foundation, InSightec-TxSonics | Undifferentiated Pleomorphic Sarcoma | 06/25 | 06/25 | | |
NCT05835154: A Checklist (Advanced Care Planning) for The Assessment of Mobility Needs in Patients With Sarcoma |
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| Not yet recruiting | N/A | 20 | US | Assessment, Assess, Questionnaire Administration, Interview, Electronic Health Record Review | Fred Hutchinson Cancer Center | Metastatic Sarcoma, Sarcoma | 09/24 | 11/24 | | |
NCT02638298: Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds |
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| Recruiting | N/A | 160 | US | Prevana Dressing, Standard Dry Gauze Dressing | Medical University of South Carolina, 3M | Sarcoma, Cancer, Infectious Disease | 07/24 | 12/24 | | |
VALUE_PERSARC, NCT05741944: The Value of a Risk Prediction Tool (PERSARC) for Effective Treatment Decisions of Soft-tissue Sarcomas Patients |
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| Recruiting | N/A | 120 | Europe | Care with the use of PERSARC, standard care | Leiden University Medical Center | Soft-tissue Sarcoma, Predictive Cancer Model | 07/24 | 07/25 | | |
NCT05560009: An Imaging Agent (Fluorodopa F 18) With Positron Emission Tomography/Magnetic Resonance Imaging for Assessing Treatment Response in Patients With High-Grade Soft Tissue Sarcomas |
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| Recruiting | N/A | 10 | US | Fluorodopa F 18, (18F)FDOPA, 18F-DOPA, 18F-FDOPA, 3-(2-Fluoro-(sup 18)F-4,5-dihydroxyphenyl)-L-alanine, 6-(18F)Fluoro-L-DOPA, Fluorine F 18 Fluorodopa, Fluorine-18-fluoro-L-DOPA, Fluorodopa (18F), FLUORODOPA F-18, L-6-(18F)Fluoro-DOPA, Magnetic Resonance Imaging, Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, Radiation Therapy, Cancer Radiotherapy, ENERGY_TYPE, Irradiate, Irradiated, Irradiation, Radiation, Radiation Therapy, NOS, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation, Surgical Procedure, Operation, Surgery, Surgery Type, Surgical, Surgical Intervention, Surgical Interventions, Surgical Procedures, Type of Surgery | Mayo Clinic | Recurrent Soft Tissue Sarcoma, Resectable Soft Tissue Sarcoma, Soft Tissue Sarcoma | 07/24 | 07/25 | | |
| Recruiting | N/A | 200 | RoW | ELISA: enzyme-linked immunosorbent assay | Peking University People's Hospital, Shanghai Hansen Biopharmaceutical Technology Co., Ltd, MEDx Translational Medicine Co., Ltd | Biomarker, Progression, Osteosarcoma, Surveillance | 07/24 | 12/24 | | |
| Not yet recruiting | N/A | 60 | NA | WCM app | University of Illinois at Chicago, Northwestern University, Northeastern Illinois University | Breast Cancer, Head and Neck Cancer, Sarcoma | 08/25 | 08/25 | | |
NCT05453292: Endoscopic Ultrasound Radiofrequency Ablation for GISTs |
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| Recruiting | N/A | 30 | RoW | Endoscopic ultrasound guided radiofrequency ablation | Instituto Ecuatoriano de Enfermedades Digestivas | Gastrointestinal Stromal Tumor (GIST) | 07/24 | 09/24 | | |
PredicT-B, NCT05978024: Predicting Radiotherapy Response and Toxicities in Soft Tissue Sarcoma of the Extremities - Cohort B |
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| Recruiting | N/A | 150 | Europe | | Royal Marsden NHS Foundation Trust | Soft Tissue Sarcoma of the Extremities | 07/24 | 07/26 | | |
NCT05490667: Clinical Study of Anlotinib Combined With Chemotherapy in the Treatment of Unresectable Advanced Desmoid Tumor |
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| Recruiting | N/A | 30 | RoW | Anlotinib, chemotherapy | Henan Cancer Hospital | Desmoid | 07/24 | 07/24 | | |
NCT00580385: Chemotherapy Resistance in Osteogenic Sarcoma and Other Solid Tumors |
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| Active, not recruiting | N/A | 763 | US | Tissue Procurement | Memorial Sloan Kettering Cancer Center, Hospital for Special Surgery, New York, Weill Medical College of Cornell University, Columbia University, Rockefeller University | Osteosarcoma | 08/24 | 08/24 | | |
NCT03896620: Recognition of Circulating Tumor DNA in Soft Tissue Sarcoma |
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| Recruiting | N/A | 50 | US | Preoperative RT, Postoperative RT, Chemotherapy, Surgery | Medical College of Wisconsin | Sarcoma | 06/25 | 06/25 | | |
| Recruiting | N/A | 201 | Europe | Fitness tracker based activity training for Arm A and B. Booklet "physical training, exercise and cancer" and an introduction about physical activity during cancer therapy for Arm A, B, C | University Hospital Tuebingen | Bronchial Carcinoma, Esophageal Carcinoma, Tumor of the Brain, Head and Neck Cancer, Pancreas Cancer, Sarcoma, Cervix Uteri Cancer | 08/24 | 08/25 | | |
| Completed | N/A | 44 | Europe | Mass spectrometry | Assistance Publique - HĆ“pitaux de Paris, Institut Curie, Sainte Anne hospital | ATRT | 02/23 | 02/23 | | |
ChiCTR2300074919: Single-cell transcriptome analysis revealed the microenvironment of gastrointestinal stromal tumors |
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| Recruiting | N/A | 10 | | NA | Colorectal Cancer Center, Department of General Surgery, West China Hospital; West China Hospital, Sichuan University, hospital fund of West China Hospital | gastrointestinal stromal tumors | | | | |
NCT02893397: Supervised Exercise in Improving Physical Fitness Before Surgery in Patients With Resectable Bone Cancer |
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| Active, not recruiting | N/A | 45 | US | Activity Monitor, Activity Tracker, Activity Tracker Device, Physical Activity Measuring Device, Exercise Intervention | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Malignant Bone Neoplasm | 08/24 | 08/24 | | |
METAGIST, NCT03963544: Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors |
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| Recruiting | N/A | 300 | Europe | oral tyrosine-kinase inhibitors (TKI) of KIT and PDGFR as per recommendations | Institut BergoniƩ, French Sarcoma Group | Gastro Intestinal Stromal Tumor | 09/24 | 12/24 | | |
NCT02331914: GIST: Assessment of Tumor Mutations and TKI Plasma Exposure |
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| Recruiting | N/A | 300 | Europe | Vena puncture for blood collection, Tumor biopsy | University Medical Center Groningen, Dutch Cancer Society | Gastro-intestinal Stromal Tumor | 09/24 | 09/24 | | |
| Active, not recruiting | N/A | 682 | Europe | Blood sampling, Tumor sampling, Stool sampling | Institut Curie | Cancer | 09/24 | 09/25 | | |
NCT02910895: A Platform of Patient Derived Xenografts (PDX) and 2D/3D Cell Cultures of Soft Tissue Sarcomas (STS) |
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| Recruiting | N/A | 40 | Europe | tumor biopsy | The Netherlands Cancer Institute, KU Leuven | Soft Tissue Sarcoma, Xenograft Model, 2D/3D Cell Cultures | 09/24 | 09/24 | | |
| Recruiting | N/A | 40 | Canada | 18F-FAZA, Pimonidazole | University Health Network, Toronto | Sarcoma | 09/24 | 09/24 | | |
PREFER, NCT05697198: PRospective rEgistry OF Advanced Stage cancER () Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine |
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| Recruiting | N/A | 2500 | US | OmniSeq Test | Labcorp Drug Development Inc | Lung Cancer, Ovarian Cancer, Uterine Cancer, Colorectal Cancer, Stomach Cancer, Esophageal Cancer, Pancreatic Cancer, Melanoma, Breast Cancer, Head and Neck Cancer, Soft Tissue Sarcoma, Rhabdomyosarcoma, Prostate Cancer | 09/24 | 09/24 | | |
| Recruiting | N/A | 190 | RoW | Imatinib, treat | Xijing Hospital | GIST | 09/24 | 09/25 | | |
NCT05747521: Anrotinib Hydrochloride Combined With Adriamycin for Neoadjuvant Treatment of High-grade Soft Tissue Sarcoma |
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| Recruiting | N/A | 85 | RoW | Anrotinib hydrochloride combined with adriamycin | Henan Cancer Hospital | Soft Tissue Sarcoma | 09/24 | 09/24 | | |
NCT00996710: Genomic Structural Variation in Cancer Susceptibility |
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| Active, not recruiting | N/A | 1275 | US | | Memorial Sloan Kettering Cancer Center, Cold Spring Harbor Laboratory, Coriell Institute, Weill Medical College of Cornell University, University of Washington Center for Mendelian Genomics | Breast Cancer, Colon Cancer, Germ Cell Cancer, Neuroblastoma, Rectal Cancer, Sarcoma | 10/24 | 10/24 | | |
NCT05746429: Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Bone Sarcoma |
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| Recruiting | N/A | 75 | US | Cognitive Behavior Therapy, CBT, CBT, cognitive behavior therapy, cognitive therapy, CT, Transcranial Direct Current Stimulation, tDCS, Interview, Placebo Administration, Questionnaire Administration | St. Jude Children's Research Hospital, National Institutes of Health (NIH), National Cancer Institute (NCI) | Bone Sarcoma | 10/24 | 10/25 | | |
NCT05548179: Exploring Clinical Trial Experiences of People With Leiomyosarcoma |
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| Not yet recruiting | N/A | 500 | NA | | Power Life Sciences Inc. | Leiomyosarcoma | 10/24 | 10/25 | | |
NCT05535283: Assessing Clinical Trial Experiences of Patients With Osteosarcoma |
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| Not yet recruiting | N/A | 500 | NA | | Power Life Sciences Inc. | Osteosarcoma | 10/25 | 10/26 | | |
BriTROC-2, NCT05537844: Longitudinal Sample Collection to Investigate Adaptation and Evolution of Ovarian High-grade Serous Carcinoma |
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| Recruiting | N/A | 250 | Europe | | Liz-Anne Lewsley, Ovarian Cancer Action | Ovarian Cancer, High Grade Serous Carcinoma, Carcinosarcoma, Ovarian, Fallopian Tube Cancer, Primary Peritoneal Carcinoma, BRCA1 Mutation, BRCA2 Mutation | 10/24 | 04/25 | | |
| Recruiting | N/A | 2850 | Europe | biological collection | Institut du Cancer de Montpellier - Val d'Aurelle | Digestive Cancer, Gynecologic Cancer, Breast Cancer, Sarcoma | 11/24 | 11/24 | | |
NCT04224467: The Application of Real-Time Near-infrared Imaging in Gynecological Surgery |
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| Recruiting | N/A | 500 | RoW | Intravenous ICG and Real-Time Near-infrared Imaging | Chen Chunlin, Chinese Academy of Sciences | Cervical Cancer, Ovarian Tumor, Endometrial Carcinoma, Uterine Myomatosis, Adenomyosis, Ovarian Cyst Benign, Ovarian Cyst Malignant, Endometriosis, Uterine Sarcoma | 11/24 | 11/24 | | |
NCT05108298: Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials |
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| Recruiting | N/A | 400 | US | Questionnaires | Eastern Cooperative Oncology Group | Breast Cancer, NOS, CNS Primary Tumor, NOS, Cervical Cancer, NOS, Colorectal Cancer, NOS, Leukemia, NOS, Lymphoma, NOS, Miscellaneous Neoplasm, NOS, Non-Rhabdomyosarcoma Soft Tissue Sarcoma, NOS, Testicular Nonseminomatous Germ Cell Tumor, NOS, Thyroid Cancer, NOS, Melanoma, Bone Cancer, NOS | 11/24 | 11/24 | | |
| Terminated | N/A | 3 | US | Dual axis endoscopic microscope, Stanford, wide field fluorescence system, Olympus, CellVizio, Mauna Kea Technologies, fluorescent Peptide, GMP, fluorescein, fluorophore, indocyanine green, ICG | Stanford University, National Institutes of Health (NIH), National Cancer Institute (NCI) | Gastrointestinal Diseases, Gastric (Stomach) Cancer, Gastrointestinal Stromal Tumor (GIST) | 09/17 | 09/17 | | |
| Recruiting | N/A | 100 | Europe | Treatment for Epitheloid Sarcoma | Italian Sarcoma Group | Epithelioid Sarcoma | 12/24 | 12/24 | | |
NCT04461171: Enhanced Recovery After Surgery in Extremity Sarcoma |
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| Recruiting | N/A | 120 | US | Enhanced Recovery After Surgery | Joshua Lawrenz | Sarcoma | 12/24 | 06/25 | | |
| Not yet recruiting | N/A | 90 | RoW | standard of care chemotherapy | UNC Lineberger Comprehensive Cancer Center, National Center for Advancing Translational Sciences (NCATS) | Kaposi Sarcoma, HIV-associated Kaposi Sarcoma, HIV Infections | 06/25 | 06/26 | | |
NCT04621201: Genomic Profiles Analysis in Children, Adolescents and Young Adult With Sarcomas |
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| Recruiting | N/A | 120 | Europe | observation and biopsy | Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna, Associazione Italiana Ematologia Oncologia Pediatrica | Diagnosed or Relapsed/Refractory Sarcomas | 12/24 | 12/26 | | |
| Recruiting | N/A | 30 | RoW | Endoscopic Full Thickness Resection | Chinese University of Hong Kong | Gastric GIST | 12/24 | 12/24 | | |
| Recruiting | N/A | 15 | US | T2* Imaging, magnetic resonance imaging, T2-star, T2* MRI | Bryan Allen, Holden Comprehensive Cancer Center, National Cancer Institute (NCI) | Radiotherapy, Magnetic Resonance Imaging, Sarcoma | 12/24 | 12/26 | | |
| Recruiting | N/A | 30 | Europe | custom made device, custom orthopaedic implantable device | Iva Hauptmannova, Adler Ortho | Bone Cancer, Bone Diseases | 12/24 | 12/24 | | |
ChiCTR1900026010: Investigation of Imatinib Pharmacogenomics in Patients With Gastrointestinal Stromal Tumor |
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| Recruiting | N/A | 600 | | N/A | The First Affiliated Hospital, Sun Yat-Sen University; The First Affiliated Hospital, Sun Yat-Sen University, National Natural Science Foundation of China | Gastrointestinal stromal tumor | | | | |
NCT05194605: Predictive Models of Treatment Responses and Survival Outcomes in Patients With Osteosarcoma |
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| Recruiting | N/A | 800 | RoW | Prediction model | West China Hospital | Osteosarcoma | 12/24 | 12/24 | | |
| Recruiting | N/A | 810 | Europe | EPIC-COS Food Frequency Questionnaire diet Evaluation, EPIC-FFQ diet Evaluation, Metabolome, Microbiota, Lymphocytes subpopulations | Istituto Ortopedico Rizzoli, International Agency for Research on Cancer | Osteosarcoma, Ewing Sarcoma | 12/24 | 12/24 | | |
| Recruiting | N/A | 250 | Europe | Diagnostic test for HHV8 exposure | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | HHV8, HHV8 Infection, HHV8-Related Malignant Neoplasm, Kaposi Sarcoma, Lung Transplant; Complications, Liver Transplant; Complications, Kidney Transplant; Complications, Castleman Disease | 12/24 | 12/25 | | |
Onco-QoL, NCT05772312: Quality of Life of Patients With Bone Tumor of the Lower Limbs Treated With Salvage Surgery |
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| Enrolling by invitation | N/A | 100 | Europe | | Istituto Ortopedico Rizzoli | Sarcoma, Ewing, Osteosarcoma, Bone Tumor | 12/24 | 12/24 | | |
NEOSarcomics, NCT02789384: CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study. |
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| Recruiting | N/A | 205 | Europe | Procedure/Surgery | Institut BergoniƩ, National Cancer Institute, France, Ministry of Health, France | Soft-tissue Sarcomas | 01/25 | 08/27 | | |
