| Sarcoma |
ChiCTR2200066276: Aggressive surgical approach with major vascular resection for retroperitoneal sarcomas |
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| Not yet recruiting | N/A | 252 | | N/A ;N/A | West China Hospital, Sichuan University; West China Hospital, Sichuan University, None | Retroperitoneal sarcomas | | | | |
NCT06165718: Study for the Clinical Roadmap and Prognosis of Pulmonary Artery Sarcoma. |
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| Recruiting | N/A | 120 | RoW | | China-Japan Friendship Hospital, The First Affiliated Hospital of Guangzhou Medical University, Beijing Chao Yang Hospital, Shanghai Pulmonary Hospital, Shanghai, China, Sir Run Run Shaw Hospital, Beijing Anzhen Hospital | Pulmonary Artery Sarcoma | 12/24 | 06/25 | | |
| Completed | N/A | 25 | RoW | 3D printed personalized extendable prosthesis | Yuxi Su | Osteosarcoma in Children | 01/23 | 03/23 | | |
NCT05631379: Influence of Nutritional Status on Oncologic and Operative Outcome in Patients Operated for Retroperitoneal Sarcoma |
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| Recruiting | N/A | 100 | Europe | Measurement of body composition with computed tomography (CT), GLIM malnutrition criteria, EWGSOP2 sarcopenia criteria, ESPEN-EASO criteria for sarcopenic obesity, Prognostic Nutritional Index (PNI), The high-sensitivity modified Glasgow prognostic score | Institute of Oncology Ljubljana | Retroperitoneal Sarcoma, Body Composition, Malnutrition, Sarcopenia, Sarcopenic Obesity, Myosteatosis | 01/23 | 12/23 | | |
NCT05813808: Low-dose Computer Tomography in Follow-up of Soft Tissue Sarcomas |
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| Completed | N/A | 50 | Europe | ultra-low-dose computed tomography | Helsinki University Central Hospital, Finnish Cancer Society | Sarcoma,Soft Tissue | 01/23 | 01/23 | | |
ChiCTR2100053479: Study the role of FGFR/ FRS2α/PI3K/AKT in well-differentiated liposarcoma/dedifferentiated liposarcoma and its clinical application prospect |
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| Recruiting | N/A | 200 | | Detection of the amplification of FRS2 gene and the expression of FGFR pathway molecules in liposarcoma, normal tissue and control tumor group (other sarcoma) | West China Hospital, Sichuan University; West China Hospital, Sichuan University, 135 project for disciplines of excellence-Clinical Research Incubation Project, West China Hospital, Sichuan University | Well differentiated liposarcoma/ dedifferentiated liposarcoma | | | | |
STARTos, NCT04644913: Long-term Evaluation of the Quality of Life of Former Patients Treated With Orthopedic Surgery, With or Without Radiotherapy |
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| Completed | N/A | 300 | Europe | Quality of life questionnaire | Institut Cancerologie de l'Ouest | Osteosarcoma in Children | 01/23 | 01/23 | | |
ChiCTR2200056174: Clinical trial of human Solid Tumor Multi-gene Mutation Combined Detection Kit (High-throughput sequencing) |
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| Not yet recruiting | N/A | | | | Peking Union Medical College Hospita ; Guangzhou Burning Rock Dx Co., Ltd, Guangzhou Burning Rock Dx Co., Ltd | Non-small cell lung cancer/colorectal cancer/gastrointestinal stromal tumor/stomach cancer/glioma/thyroid cancer/breast cancer/ovarian cancer/melanoma/cholangiocarcinoma/urothelial carcinoma/prostate | | | | |
CHIPT, NCT04832620: Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas |
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| Recruiting | N/A | 40 | Europe | | Leiden University Medical Center, HollandPTC, Varian Medical Systems | Bone Neoplasm of Vertebral Column, Chordoma, Chondrosarcoma, Magnetic Resonance Imaging, PET-CT, Proton Therapy | 12/25 | 12/27 | | |
NCT05397522: The Effects of Observer Presence and Type on Patients' Perception of Exercise After Bone Tumor Resection-A Qualitative Study |
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| Not yet recruiting | N/A | 30 | RoW | Supervised Exercise by a physiotherapist via face to face, Supervised Exercise by a physiotherapist via video conference | Istanbul Medeniyet University | Bone Cancer, Tumor | 02/23 | 03/23 | | |
ChiCTR2200062395: Real world retrospective analysis of precise individualized comprehensive treatment for bone and soft tissue sarcoma |
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| Not yet recruiting | N/A | 200 | | Individualized comprehensive treatment | Nanjing Drum Tower Hospital，The Affiliated Hospital of Nanjing University Medical School; Nanjing Drum Tower Hospital，The Affiliated Hospital of Nanjing University Medical School, fundings for Clinical Trials from the Affiliated Drum Tower Hospital, Medical School of Nanjing University | bone and soft tissue sarcoma | | | | |
NCT04148378: A Pilot Study to Explore the Role of Gut Flora in Colorectal Cancer |
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| Recruiting | N/A | 100 | US | No intervention | ProgenaBiome | Colorectal Cancer, Colorectal Neoplasms, Colorectal Carcinoma, Colorectal Adenocarcinoma, Colorectal Cancer Metastatic, Colorectal Sarcoma | 03/23 | 07/23 | | |
NCT03630601: Photoacoustic Imaging in Diagnosing Changes in Tumors in Participants With Breast Cancer, Sarcoma, Skin Cancer, or Soft Tissue Malignancy and Healthy Volunteers |
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| Terminated | N/A | 7 | US | Photoacoustic Imaging | Roswell Park Cancer Institute, National Cancer Institute (NCI) | Breast Carcinoma, Healthy Subject, Malignant Soft Tissue Neoplasm, Sarcoma, Skin Carcinoma | 03/23 | 03/23 | | |
NCT05746910: Patient's Perception of Exercise After Bone Tumor Resection-A Qualitative Study |
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| Recruiting | N/A | 10 | RoW | | Istanbul Medeniyet University | Bone Cancer Tumor | 03/23 | 04/23 | | |
NCT04071704: Assessing Health-related Quality of Life in Sarcoma Patients |
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| Recruiting | N/A | 689 | Europe, RoW | | The Netherlands Cancer Institute, Radboud University Medical Center, Leiden University Medical Center, Centre Leon Berard, University Hospital Carl Gustav Carus, Heidelberg University, Johannes Gutenberg University Mainz, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, National Cancer Institute, Naples, Maria Sklodowska-Curie National Research Institute of Oncology, Hospital San Carlos, Madrid, Royal Marsden NHS Foundation Trust, Beatson West of Scotland Cancer Centre, University Hospital Southampton NHS Foundation Trust, Royal National Orthopaedic Hospital NHS Trust, Bank of Cyprus Oncology Centre, Institut Català d'Oncologia, University of Adelaide, King Hussein Cancer Center, Oslo University Hospital, Erasmus Medical Center, University Medical Center Groningen, Centre Oscar Lambret, Aretaieio Hospital, Hospital Universitario Fundación Jiménez Díaz, The Christie NHS Foundation Trust, Ain Shams University, Prince of Wales Hospital, Shatin, Hong Kong, Sheba Medical Center | Sarcoma | 03/23 | 03/23 | | |
NCT05510973: Evaluation of Advanced HIV Disease Differentiated Care Model in Malawi |
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| Active, not recruiting | N/A | 700 | RoW | Enhanced package for AHD care | Elizabeth Glaser Pediatric AIDS Foundation, Bill and Melinda Gates Foundation | Opportunistic Infections, HIV-Related, Cryptococcal Infections, AIDS With Tuberculosis, AIDS-related Kaposi Sarcoma, AIDS and Infections | 03/23 | 06/23 | | |
NCT05408897: Prediction of Postoperative Treatment Efficacy and Recurrence Risk of High-risk GIST Based on Liquid Biopsy MRD |
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| Recruiting | N/A | 45 | RoW | liquid biopsy | Peking University People's Hospital | Gastrointestinal Stromal Tumors, Minimal Residual Disease | 04/23 | 04/28 | | |
ChiCTR2100044869: Clinical significance of nutritional and inflammatory markers in patients receiving neoadjuvant with osteosarcoma |
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| Suspended | N/A | 200 | | Nil | Shanghai Jiao Tong University Affiliated Sixth People's Hospital; Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University Affiliated Sixth People's Hospital | osteosarcoma | | | | |
NCI-2021-10994, NCT05169151: Mobility and Physical Activity in Adolescent and Young Adult Cancer Patients or Survivors at Risk for Cardiovascular Morbidity and Frailty, The MOBILE AYA Study |
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| Withdrawn | N/A | 500 | US | Smartphone Application, App, Smartphone App | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Central Nervous System Neoplasm, Hodgkin Lymphoma, Malignant Solid Neoplasm, Non-Hodgkin Lymphoma, Sarcoma | 04/23 | 04/23 | | |
NCT05284305: Desmoid Tumor and Pregnancy: Effect of Pregnancy on Disease Control and Effect of Diagnosis on Pregnancy History. |
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| Recruiting | N/A | 400 | Europe, Canada, US | Pregnancy | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, University of Padova, Institut Curie, Dana-Farber/Brigham and Women's Cancer Center, Mount Sinai Hospital, Canada, Desmoid Foundation Italia, Istituto Oncologico Veneto IRCCS | Desmoid, Desmoid; Abdominal, Pregnancy Loss, Pregnancy Complications | 04/23 | 05/23 | | |
| Recruiting | N/A | 600 | Europe | Collection of Leiomyoma samples, Obtainment of blood sample (peripheral blood) and tumour tissue sample, Collection of Leiomyosarcoma samples, Collection of control samples, Obtainment of blood sample (peripheral blood) | Igenomix | Leiomyoma, Uterine, Leiomyosarcoma Uterus | 05/23 | 05/23 | | |
ChiCTR2200058838: Identifying the Risk Factors and Prognosis in Patients with Pelvic and Spinal Osteosarcomas Based on SEER Database |
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| Not yet recruiting | N/A | 80 | | No intervention | Hangzhou Third People's Hospital; Hangzhou Third People's Hospital, None | Pelvic and Spinal Osteosarcomas | | | | |
ChiCTR2000031408: Single center, non-randomized controlled clinical trial of antitumor efficiency of hydroxyapatite nanoparticles (HANPs) |
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| Not yet recruiting | N/A | 60 | | Implantation of HANPs | West China Hospital, Sichuan University; West China Hospital, Sichuan University, National Key Research and Development Program of China | Desmoid tumor, synovial sarcoma, giant cell tumor, chordoma | | | | |
NCT05337163: A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China |
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| Completed | N/A | 659 | RoW | Diagnostic Test: Sputum DNA methylation analysis, LUNSAFE, chest CT or pathological examination | Creative Biosciences (Guangzhou) Co., Ltd., Guangzhou Xiangkang Medical Research Co., Ltd. | Lung Cancer, Small Cell Lung Cancer, Non-Small Cell Lung Cancer, Squamous Cell Carcinoma, Adenocarcinoma, Large Cell Carcinoma, Adenosquamous Carcinoma, Sarcomatoid Carcinoma, Respiratory Tract Infection, Acute Bronchitis, Pneumonia, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease, Tuberculosis, Lung Neoplasm, Pulmonary Interstitial Fibrosis | 05/23 | 08/23 | | |
| Recruiting | N/A | 64 | Europe | Proton radiation, Carbon Ion radiation | University Hospital Heidelberg | Sarcoma,Soft Tissue | 05/26 | 05/27 | | |
NCT04571229: Expanded Access Use of L-MTP-PE for the Treatment of Osteosarcoma |
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| Available | N/A | | US | L-MTP-PE | Memorial Sloan Kettering Cancer Center | Osteosarcoma | | | | |
ChiCTR2100054019: Clinical value and exploration of Apatinib combined with SHR-1210 in perioperative adjuvant treatment of retroperitoneal sarcomas |
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| Recruiting | N/A | 93 | | Apatinib combined with SHR-1210( Before the surgery) ;surgery | Beijing Cancer Hospital / Peking University Cancer Hospital; Peking University Cancer Hospital, Capital Health Development of Special Funding Support | Retroperitoneal Sarcoma | | | | |
ChiCTR2300067379: Precision diagnosis and stratification treatment of myeloid sarcoma |
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| Recruiting | N/A | 50 | | none | West China Hospital of Sichuan University; West China Hospital of Sichuan University, Clinical incubation project of West China Hospital of Sichuan University | Myeloid Sarcoma (MS) | | | | |
NCT05442333: Adjuvant Versus Neo-adjuvant Radiotherapy in Patients With Resectable Soft Tissue Sarcoma in Extremities : Wound Complications |
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| Active, not recruiting | N/A | 20 | RoW | surgical resection with safety margin, pre operative radiotherapy, post operative radiotherapy | Ain Shams University | Resectable Soft Tissue Sarcoma, Extremities, Radiotherapy Wound Complications | 06/23 | 06/23 | | |
NCT05665868: Study on Integrated Nursing Strategy for Patients With Gastrointestinal Stromal Tumors After Targeted Therapy |
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| Recruiting | N/A | 62 | RoW | integrated care mode, conventional care mode | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Nursing Caries, Gastrointestinal Stromal Tumors | 06/23 | 04/25 | | |
NCT02822495: Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia or Malignancies |
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| No Longer Available | N/A | | NA | tabelecleucel, tab-cel®, ATA129, EBV-CTL | Atara Biotherapeutics | Epstein-Barr Virus (EBV) Infections, Lymphoproliferative Disorders, EBV+ Associated Lymphoma, EBV+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Epstein-Barr Viremia, Lymphoma, AIDS-related, Epstein-Barr Virus-associated Lymphoproliferative Disease (EBV+ LPD) With Primary Immunodeficiency (PID), Leiomyosarcoma (LMS), Nasopharyngeal Carcinoma (NPC), Epstein-Barr Virus-associated Lymphoproliferative Disease (EBV+ LPD) With Acquired Immunodeficiency (AID), Solid Organ Transplant Complications, Stem Cell Transplant Complications | | | | |
NCT06244251: Comparison Between Laparoendoscopic Single-site Surgery and Multi-port Laparoscopy in Treating Uterine Fibroids |
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| Active, not recruiting | N/A | 5000 | RoW | TU-LESS, MPLS | West China Second University Hospital | Uterine Fibroid, Uterine Sarcoma, Uterine Leiomyosarcoma | 08/26 | 12/26 | | |
NCT03206450: Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors |
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| Active, not recruiting | N/A | 224 | Canada, US | Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Laboratory Biomarker Analysis, Questionnaire Administration | Children's Oncology Group, National Cancer Institute (NCI) | Osteosarcoma | 06/23 | 06/28 | | |
(SELNET), NCT04181970: Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK |
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| Recruiting | N/A | 5000 | Europe, RoW | Quality assessment | Grupo Espanol de Investigacion en Sarcomas | Soft-tissue Sarcoma, Gastrointestinal Stromal Tumors, Bone Sarcoma | 09/24 | 09/25 | | |
ChiCTR2100048715: Clinical trial of Chidamide in combination with Anlotinib for refractory and advanced soft tissue sarcoma after failure of standard therapy |
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| Not yet recruiting | N/A | 56 | | Treatment was performed according to the combination regimen of cidabentamine and amlotinib | Shanghai Sixth People's Hospital; Shanghai Sixth People's Hospital, Shanghai Sixth People's Hospital | soft tissue sarcoma | | | | |
| Recruiting | N/A | 42 | Europe | Protons, carbon ions | University Hospital Heidelberg | Soft Tissue Sarcoma | 07/25 | 07/25 | | |
NCT06040229: Retrospective Study in FFPE Samples From Younger Patients With Rhabdomyosarcoma |
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| Completed | N/A | 6 | RoW | | Shandong First Medical University, Shandong Tumor Hospital | Alveolar Childhood Rhabdomyosarcoma, Embryonal Childhood Rhabdomyosarcoma, Recurrent Childhood Rhabdomyosarcoma | 07/23 | 09/23 | | |
1206, NCT06282237: Clinical Evaluation, Motor Performance and Quality of Life in Patients Affected by Soft Tissue Sarcomas, Undergoing Surgical Treatment: Observational Study |
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| Recruiting | N/A | 13 | Europe | survey | Fondazione Policlinico Universitario Campus Bio-Medico, Fondazione Don Carlo Gnocchi Onlus | Sarcoma | 07/25 | 07/26 | | |
NCT03874455: Tazemetostat Expanded Access Program for Adults With Solid Tumors |
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| No Longer Available | N/A | | NA | Tazemetostat, EPZ-6438 | Epizyme, Inc. | Epithelioid Sarcoma (Ex-US Only), Spindle Cell Sarcoma, Sinonasal Carcinoma, Small Cell Carcinoma of the Ovary Hypercalcemic Type, Thoracic Sarcoma, Poorly Differentiated Chordoma, ATRT, Malignant Rhabdoid Tumor of Kidney, Malignant Rhabdoid Tumor of Ovary, Malignant Rhabdoid Tumor, Myxoid Spindle Cell Sarcoma, Epithelioid Malignant Peripheral Nerve Sheath Tumor, Chondrosarcoma, Renal Cell Carcinoma, Myoepithelial Carcinoma, Synovial Sarcoma, Renal Medullary Carcinoma, Malignant Mesothelioma, Desmoplastic Small Round Cell Tumor (DSRCT), Intramedullary Spinal Cord Schwannomatosis | | | | |
| Recruiting | N/A | 25 | Europe | Neoadjuvant RT, Pre-radiotherapy mpMRI, Post-radiotherapy mpMRI, Tumor resection | Centre Leon Berard | Soft Tissue Sarcoma, Adult Soft Tissue Sarcoma, Resectable Soft Tissue Sarcoma | 07/23 | 01/24 | | |
NCT05131815: The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors |
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| Active, not recruiting | N/A | 8 | US | Virtual group based physical activity (BurnAlong) and Social Media Discussion Board | Cedars-Sinai Medical Center, Walter Reed National Military Medical Center | Cancer, Cancer Metastatic, Neoplasms, Breast Cancer, Lung Cancer, Thyroid Cancer, Lymphoma, Lymphoma, Non-Hodgkin, Hodgkin Lymphoma, Leukemia, Sarcoma, Skin Cancer, Bone Cancer, Gynecologic Cancer, Pancreas Cancer, Multiple Myeloma, Colorectal Cancer, Gastrointestinal Cancer, Prostate Cancer, Glioblastoma, Brain Cancer, Head and Neck Cancer | 07/23 | 01/25 | | |
NCT05596565: The Effects of Observer Presence and Type on Patients' Perception of Exercise in Patients With Soft Tissue Sarcoma |
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| Not yet recruiting | N/A | 30 | RoW | Supervised Exercise by a physiotherapist via face to face, Supervised Exercise by a physiotherapist via video conference | Istanbul Medeniyet University | Soft Tissue Sarcoma | 07/23 | 09/23 | | |
NCT05974410: Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer Patients |
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| Available | N/A | | NA | AVM0703, Hydrocortisone, Proton pump inhibitor | AVM Biotechnology Inc | Glioblastoma, Squamous Cell Carcinoma, Hodgkin Lymphoma, Non-hodgkin Lymphoma, Breast Cancer, Prostate Cancer, Gastric Cancer, Ovarian Cancer, Acute Leukemia, Pancreatic Cancer, Spindle Cell Sarcoma, Cancer, Tumor, Solid, Tumor, Brain | | | | |
PREVAILctDNA, NCT04566614: Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies |
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| Recruiting | N/A | 294 | Europe | ctDNA blood sampling | Royal Marsden NHS Foundation Trust | Neoplasm, Colorectal, Neoplasm of Lung, Neoplasm, Bladder, Neoplasms Pancreatic, Biliary Tract Neoplasms, Gastro Intestinal Stromal Tumour | 07/23 | 12/25 | | |
NCT03716089: Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site |
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| Recruiting | N/A | 246 | RoW | Laparoscopic resection | Fujian Medical University | GIST of Stomach, Gastric Cancer, Surgery, Complication | 08/23 | 10/25 | | |
NCT04022512: Accuracy of Deep-learning Algorithm for Detection and Risk Stratification of Lung Nodules |
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| Completed | N/A | 100 | RoW | computed tomography | Chinese University of Hong Kong, IBM China/Hong Kong Limited | Osteogenic Sarcoma | 08/23 | 01/24 | | |
NCT05729425: Evaluating the Accuracy of Microvessel Ultrasound Imaging for Detecting Extent of Disease in Patients With Angiosarcoma of the Skin |
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| Terminated | N/A | 1 | US | Ultrasound Microvessel Imaging, 3D Ultrasound Microvessel Imaging, UMI | Mayo Clinic | Skin Angiosarcoma | 08/23 | 08/23 | | |
ChiCTR2200062796: A single-center study comparing the safety and efficacy of endoscopic versus laparoscopic resection of gastrointestinal stromal tumors >=3cm in diameter |
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| Not yet recruiting | N/A | 310 | | endoscopic resections ;laparoscopic resection | Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University; Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University | gastric stromal tumor | | | | |
ChiCTR2300070624: Study on the mechanism of liposarcoma-derived exosomes mediating macrophage polarization in tumor microenvironment |
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| Recruiting | N/A | 60 | | N/A ;N/A | West China Hosipital of Sichuan University; West China Hospital of Sichuan University, Sichuan University West China Hospital 1.3.5 ProjectZYJC21065 | Retroperitoneal tumor | | | | |
NCT05041036: Individual Patient Compassionate Use of Nirogacestat |
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| Available | N/A | | NA | Nirogacestat (Gamma Secretase Inhibitor) | SpringWorks Therapeutics, Inc. | Desmoid Tumor, NOTCH Gene Mutation Positive Tumors | | | | |
ChiCTR2000030250: Phase II clinical trial of albumin-bound paclitaxel plus gemcitabine in the treatment of metastatic/locally unresectable soft tissue sarcoma: a single-center, open, single-arm study |
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| Recruiting | N/A | 35 | | albumin-bound paclitaxel plus gemcitabine | Department of Orthopedics, the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital; The Affiliated Cancer Hospital of Zhengzhou University, self-raised | Soft tissue sarcoma | | | | |
ChiCTR2100047737: A medical records based study for the clinicopathological features of follicular dendritic cell sarcoma |
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| Not yet recruiting | N/A | 45 | | None | Institute of Pathology, The First Affiliated Hospital of the Army Military Medical University of PLA; The First Affiliated Hospital of Army Medical University, PLA, None | follicular dendritic cell sarcoma | | | | |
ChiCTR2000036618: Precision therapy strategy for osteosarcoma based on molecular typing: a prospective, single-center, one-brachial umbrella phase II exploratory clinical study |
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| Not yet recruiting | N/A | 18 | | Everolimus 5mg qd + Anlotinib 8mg-12mg day 1-21，28-day cycle ;Camrelizumab 3mg/kg + Ipilimumab 1 mg/kg, 21-days cycle ;Palbociclib 125mg day 1-21 + gemcitabine 600mg/m2 day 1,8,15,22, 28-days cycle ;Olaparib 300mg bid day 1-14 + gemcitabine 600mg/m2 day 1,8,15,22, 28-days cycle ;Metformin 2000mg qd + gemcitabine 675mg/m2 day 1,8, docetaxol 900mg/m2 day 8， 21-days cycle | Shanghai General Hospital; Shanghai General Hospital, Project special fund | osteosarcoma | | | | |
NCT06204198: Clinicopathological Features and Molecular Typing of Invasive Fibroma of Abdominal Wall |
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| Recruiting | N/A | 150 | RoW | No intervention | Shandong Provincial Hospital | Aggressive Fibromatosis of Abdominal Wall (Disorder) | 02/24 | 09/24 | | |
NCT03108677: Circulating Exosome RNA in Lung Metastases of Primary High-Grade Osteosarcoma |
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| Active, not recruiting | N/A | 90 | RoW | Blood samples | Ruijin Hospital | Lung Metastases, Osteosarcoma | 09/23 | 12/23 | | |
NCT04091295: BLESSED: Expanded Access for DeltaRex-G for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast |
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| Available | N/A | | US | DeltaRex-G, DeltaRex-G Retroviral Vector Encoding a Cyclin G1 Inhibitor | Aveni Foundation | Pancreatic Cancer, Osteosarcoma, MPNST (Malignant Peripheral Nerve Sheath Tumor), Chondrosarcoma, Soft Tissue Sarcoma, Chordoma, Sarcoma, Carcinoma of Breast | | | | |
| Available | N/A | | US | eflornithine HCl, DFMO | Giselle Sholler, K C Pharmaceuticals Inc., USWM, LLC | Neuroblastoma, Medulloblastoma, Typical Teratoid Rhabdoid Tumor, Embryonal Tumor With Abundant Neuropil and True Rosettes, Ependymoblastoma, Medulloepithelioma | | | | |
NCT04681248: Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors |
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| Available | N/A | | US | DKN-01 | Leap Therapeutics, Inc. | Esophageal Neoplasm, Adenocarcinoma of the Gastroesophageal Junction, GastroEsophageal Cancer, Squamous Cell Carcinoma, Gastric Adenocarcinoma, Endometrial Cancer, Uterine Cancer, Ovarian Cancer, Carcinosarcoma, Gastric Cancer | | | | |
NCT03994627: Olaratumab (LY3012207) Patient Access for Soft Tissue Sarcoma |
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| Available | N/A | | Europe, Canada, US, RoW | Olaratumab, LY3012207 | Eli Lilly and Company | Soft Tissue Sarcoma | | | | |
NCT00919269: Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma |
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| Completed | N/A | 150 | Europe, Canada, US, RoW | Cytology Specimen Collection Procedure, Cytologic Sampling, Laboratory Biomarker Analysis | Children's Oncology Group, National Cancer Institute (NCI) | Adult Rhabdomyosarcoma, Childhood Desmoplastic Small Round Cell Tumor, Chordoma, Desmoid-Type Fibromatosis, Metastatic Childhood Soft Tissue Sarcoma, Non-Metastatic Childhood Soft Tissue Sarcoma, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Adult Soft Tissue Sarcoma, Recurrent Childhood Rhabdomyosarcoma, Recurrent Childhood Soft Tissue Sarcoma, Rhabdomyosarcoma, Stage I Adult Soft Tissue Sarcoma AJCC v7, Stage II Adult Soft Tissue Sarcoma AJCC v7, Stage III Adult Soft Tissue Sarcoma AJCC v7, Stage IV Adult Soft Tissue Sarcoma AJCC v7, Untreated Childhood Rhabdomyosarcoma | 09/23 | 09/23 | | |
NCT00899990: Collecting and Storing Biological Samples From Patients With Ewing Sarcoma |
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| Completed | N/A | 908 | Europe, Canada, US, RoW | Laboratory Biomarker Analysis | Children's Oncology Group, National Cancer Institute (NCI) | Askin Tumor, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | 09/23 | 09/23 | | |
NCT00899275: Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma |
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| Completed | N/A | 957 | Canada, US, RoW | Cytology Specimen Collection Procedure, Cytologic Sampling | Children's Oncology Group, National Cancer Institute (NCI) | Osteosarcoma | 09/23 | 09/23 | | |
ChiCTR2000036699: A prospective randomized controlled trial for osteosarcoma precise treatment by dynamic detecting of circulating tumor cells |
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| Not yet recruiting | N/A | 50 | | Treatment based on dynamic detecting ;Treatment based on clinical factors | Shanghai General Hospital; Shanghai General Hospital, Special funds | Osteosarcoma | | | | |
NCT05062707: Early Ageing During Therapy in AYA Cancer Patients |
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| Recruiting | N/A | 120 | Europe | Blood sampling | University Medical Center Groningen, UMCG Kanker Researchfonds | Cancer, Leukemia, Hodgkin Lymphoma, Testicular Cancer, Osteosarcoma, Ewing Sarcoma, Breast Cancer, Cervical Cancer | 07/25 | 07/25 | | |
ChiCTR2300070011: Safety, efficacy and the optimal duration of preoperative imatinib in locally advanced gastric gastrointestinal stromal tumors: a retrospective cohort study |
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| Recruiting | N/A | 41 | | None | Department of General Surgery, Zhongshan Hospital, Fudan University School of Medicine; Zhongshan Hospital Affiliated to Fudan University, National Natural Science Foundation of China (81773080) | gastrointestinal stromal tumor | | | | |
| Recruiting | N/A | 100 | Europe | No Intervention | Technische Universität Dresden, SOS Desmoid e.V., Universitätsmedizin Mannheim | Desmoid Tumor, Quality of Life | 02/24 | 12/24 | | |
ChiCTR2300073633: Application of 3D Printing Technology in Surgical Guidance for Complex Retroperitoneal Sarcoma: A Retrospective Analysis |
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| Not yet recruiting | N/A | 251 | | N/A ;N/A | Guangdong Provincial Hospital of Traditional Chinese Medicine; Guangdong Provincial Hospital of Traditional Chinese Medicine, N/A | Retroperitoneal tumor | | | | |
| Active, not recruiting | N/A | 35 | Canada | PET MRI scan | University Health Network, Toronto | Retroperitoneal Sarcoma | 12/24 | 12/24 | | |
NCT00026754: Eligibility Screening for the NIH Intramural Research Program Clinical Protocols |
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| Enrolling by invitation | N/A | 24000 | US | | National Cancer Institute (NCI) | Breast Cancer, Prostate Cancer, Lung Cancer, Sarcoma, Melanoma | | | | |
NCT01109394: Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies |
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| Recruiting | N/A | 6035 | US | | National Cancer Institute (NCI) | Sarcoma, Endocrine Tumors, Neuroblastoma, Retinoblastoma, Renal Cancer | | | | |
| Completed | N/A | 2136 | US | | National Cancer Institute (NCI) | Retinoblastoma, Melanoma, Sarcoma | 03/24 | 03/24 | | |
NCT05615545: Cryoablation for Advanced Bone and Soft Tissue Tumors |
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| Recruiting | N/A | 30 | RoW | Cryoablation | Henan Cancer Hospital | Sarcoma, Cryoablation | 10/24 | 10/24 | | |
NCT05440357: Second-line Pharmacotherapy Patterns and Outcomes of Advanced Gastrointestinal Stromal Tumor: A Real-world Study |
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| Recruiting | N/A | 100 | RoW | | Xinhua Zhang, MD, Guangdong Provincial People's Hospital, Nanfang Hospital, Southern Medical University, Sixth Affiliated Hospital, Sun Yat-sen University, Peking University Shenzhen Hospital, Cancer Hospital of Guangxi Medical University, Hainan Cancer Hospital, The First Affiliated Hospital of Nanchang University, Second Affiliated Hospital of Nanchang University, Yunnan Cancer Hospital, Chongqing University Cancer Hospital | Gastrointestinal Stromal Tumors | 09/24 | 09/24 | | |
ChiCTR2000039230: Value of 18F-FDG PET/CT in in the diagnosis and differential diagnosis of pulmonary artery sarcoma |
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| Recruiting | N/A | | | | China-Japan Friendship Hospital; China-Japan Friendship Hospital, Obtain funds through project application | Pulmonary Artery Sarcoma | | | | |
NCT05453409: Study on Clinical Features, Treatment Mode and Survival of Sarcoma |
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| Recruiting | N/A | 6000 | RoW | No intervention | Henan Cancer Hospital | Sarcoma | 12/24 | 12/24 | | |
NCT02307630: PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot Study |
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| Active, not recruiting | N/A | 7 | US | 124I-Humanized 3F8 | Memorial Sloan Kettering Cancer Center, Y-mAbs Therapeutics | Melanoma, Neuroblastoma, Sarcoma | 11/24 | 11/24 | | |
NCT03686566: Pediatric Solid Tumor Metabolism [A Prospective Study Exploring Metabolism of Solid Tumors in Pediatrics] |
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| Completed | N/A | 84 | US | 13C-glucose, U-C glucose, No glucose infusion | University of Texas Southwestern Medical Center | Neuroblastoma, Sarcoma, Pediatric Cancer | 01/24 | 01/24 | | |
NCT00006518: Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer |
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| Recruiting | N/A | 999 | US | | National Cancer Institute (NCI) | HIV, Kaposi's Sarcoma, Lymphomas, Multicentric Castleman's Disease, Primary Effusion Lymphoma | | | | |
NCT06129903: Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma |
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| Recruiting | N/A | 70 | US | referral to the Memorial Sloan-Kettering Cancer Center (MSK) Department of Psychiatry and Behavioral Sciences. | Memorial Sloan Kettering Cancer Center | Sarcoma, Bone Sarcoma, Soft Tissue Sarcoma | 11/26 | 11/26 | | |
| Recruiting | N/A | 34 | Europe | Blood samples, Localized sarcoma, Metastatic sarcoma | Centre Georges Francois Leclerc | Sarcoma | 11/24 | 11/25 | | |
NCT05132738: Ripretinib Used for Resectable Metastatic GIST After Failure of Imatinib Therapy |
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| Recruiting | N/A | 20 | RoW | Ripretinib treatment | RenJi Hospital | Gastrointestinal Stromal Tumors | 11/23 | 11/23 | | |
NCT00582647: Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract |
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| Active, not recruiting | N/A | 6000 | US | | Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI) | Esophageal Cancer, Bile Duct Neoplasms, Gastric Cancer, Liver Cancer, Melanoma, Pancreatic Cancer, Sarcoma | 12/24 | 12/24 | | |
NCT01831609: Biomarker Analysis of Solid Cancers Such as Gastrointestinal Cancer |
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| Recruiting | N/A | 1000 | RoW | | Samsung Medical Center | Sarcoma | 12/23 | 12/24 | | |
| Recruiting | N/A | 30 | Europe | | University Hospital, Strasbourg, France | Desmoid Tumors | 12/23 | 12/23 | | |
ESPACE, NCT04224064: Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas |
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| Recruiting | N/A | 158 | Europe | Blood sampling | Institut du Cancer de Montpellier - Val d'Aurelle | Liposarcoma, Atypical Lipomatous Tumor | 12/23 | 12/25 | | |
NCT04474678: Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!") |
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| Completed | N/A | 240 | Europe | "My Logbook! - I know my way around!" | Medical University of Vienna, St. Anna Kinderspital, Austria, Charite University, Berlin, Germany, Cnopfsche Kinderklinik, Nürnberg, Kepler University Hospital, University Hospital, Saarland, Hannover Medical School, Krankenhaus Bozen, Goethe University, Universitätsklinikum Hamburg-Eppendorf, Universitätsklinikum Leipzig, University Hospital Muenster, University Hospital Tuebingen, Salzburger Landeskliniken, Leuwaldhof St.Veit (Kinder- und Jugendreha), University Hospital, Essen, Medical University of Graz, University Hospital Erlangen, Wuerzburg University Hospital, Klinik Bad Oexen, Germany, Universitätsklinikum Köln, University Hospital Schleswig-Holstein, University Hospital Carl Gustav Carus, Universitätsmedizin Mannheim, University Hospital Regensburg, Luca-Dethlefsen-Hilfe e.V., Insel Gruppe AG, University Hospital Bern, Staedtisches Klinikum Karlsruhe | Brain Tumor, Neurofibromatoses, Sarcoma, Leukemia, Hematologic Diseases, Neuroblastoma | 12/23 | 12/23 | | |
| Recruiting | N/A | 300 | Europe | Treatment of Breast Sarcoma according clinical practice (includes drugs, surgery or any other received treatments) | Italian Sarcoma Group | Breast Sarcoma | 12/23 | 12/23 | | |
NCT04960332: Effect of Negative Pressure Wound Therapy After Surgical Removal of Deep-Seated High-Malignant Soft Tissue Sarcomas of the Extremities and Trunk Wall. |
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| Recruiting | N/A | 160 | Europe | Prevena | Rigshospitalet, Denmark | Sarcoma, Cancer, Neoplasms, Connective and Soft Tissue | 12/23 | 12/24 | | |
| Recruiting | N/A | 60 | Europe | Functional outcome, Health related quality of life (HRQoL) assessment | Universitaire Ziekenhuizen KU Leuven | Soft Tissue Sarcoma, Bone Sarcoma | 07/25 | 07/25 | | |
| Not yet recruiting | N/A | 50 | Europe | Liver Transplantation | Hospital Universitario Virgen de la Arrixaca | Liver Diseases, Liver Cancer, Liver Metastases, Liver Neoplasms, Liver Mass, Liver Carcinoma, Liver Transplant; Complications, Liver Transplant Disorder, GIST, GIST, Malignant, Gastrointestinal Stromal Tumors, Gastrointestinal Stromal Tumor of Duodenum, Gastrointestinal Stromal Tumor of Rectum, Gastrointestinal Stromal Tumor of Other Sites, Gastrointestinal Stromal Tumor, Unspecified Site, Gastrointestinal Stromal Tumor of Stomach, Gastrointestinal Stromal Tumor of Esophagus (Disorder), Gastrointestinal Stromal Tumor by AJCC V8 Stage, Gastrointestinal Stromal Tumor, Malignant, Gastrointestinal Stromal Tumor (GIST) of the Gastrointestinal Tract, Gastrointestinal Stromal Tumor of Small Intestine (Disorder), Gastrointestinal Stromal Tumor of Large Intestine (Disorder), Metastases to Liver, Metastatic Liver Cancer, Metastasis, Metastases, Liver Transplantation, Transplant Oncology | 12/23 | 12/25 | | |
CAMPERR, NCT05366881: cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease |
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| Recruiting | N/A | 7000 | US | | Adela, Inc | Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer, Colorectal Cancer, Endometrial Cancer, Esophageal Cancer, Stomach Cancer, Head and Neck Cancer, Hepatobiliary Cancer, Leukemia, Lung Cancer, Lymphoma, Multiple Myeloma, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Renal Cancer, Sarcoma, Thyroid Cancer | 09/25 | 12/26 | | |
| Withdrawn | N/A | 162 | Europe | | Aesculap AG, B.Braun Surgical SA | Gastrointestinal Stromal Tumors, Gastrointestinal Neoplasms, Digestive System Neoplasm, Stomach Tumor, Small Intestine Tumor, Colon Tumor, Rectum Tumor | 12/23 | 12/23 | | |
EHE, NCT06408441: The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN) |
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| Recruiting | N/A | 100 | Europe | | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, EHE Rare Cancer Charity UK | Epithelioid Hemangioendothelioma, Sarcoma,Soft Tissue | 12/33 | 12/33 | | |
| Recruiting | N/A | 16 | Europe | High Intensity Focused Ultrasound Ablation, Tumour Biopsy and Venous Blood Tests | Oxford University Hospitals NHS Trust, Surgical Intervention Trials Unit, Oxford, UK, NIHR Direct Delivery Team, Oxford Radiology Research Unit, Churchill Hospital, Oxford, UK | Soft Tissue Sarcoma, Desmoid; Abdominal | 10/24 | 10/25 | | |
NCT00898755: Collecting and Storing Tissue From Young Patients With Cancer |
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| Recruiting | N/A | 213 | Canada, US | Cytology Specimen Collection Procedure, Cytologic Sampling, Laboratory Biomarker Analysis | Children's Oncology Group, National Cancer Institute (NCI) | Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Central Nervous System Neoplasm, Ewing Sarcoma, Germ Cell Tumor, Leukemia, Lymphoma, Malignant Neoplasm, Neuroblastoma, Osteosarcoma, Retinoblastoma, Rhabdoid Tumor, Rhabdomyosarcoma, Soft Tissue Sarcoma | 12/24 | | | |
NCT05216029: Oncology Dashboard for the Improvement of Operational Efficiency and Patients Outcomes in Patients With Sarcoma |
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| Active, not recruiting | N/A | 92 | US | Best Practice, standard of care, standard therapy, Informational Intervention, Questionnaire Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Sarcoma | 12/25 | 12/25 | | |
Micros, NCT03737435: Tumor Microenvironment in Patients With Localized Osteosarcoma Treated With Mifamurtide: a Translational Study |
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| Recruiting | N/A | 80 | Europe | | Istituto Ortopedico Rizzoli | Localized Osteosarcoma | 06/24 | 06/24 | | |
| Completed | N/A | 41 | US | Diagnostic Microscopy, Human Intravital Microscopy, IVM, HIVM, Fluorescein Sodium Injection, AK-Fluor, Fluorescite | Mayo Clinic | Solid Tumor, Adult, Clinical Stage IV Gastric Cancer AJCC v8, Gastric Carcinoma, Malignant Solid Neoplasm, Metastatic Colorectal Carcinoma, Metastatic Gastric Carcinoma, Metastatic Primary Malignant Brain Neoplasm, Metastatic Sarcoma, Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8, Resectable Colorectal Carcinoma, Resectable Liver and Intrahepatic Bile Duct Carcinoma, Resectable Pancreatic Carcinoma, Resectable Sarcoma, Stage IV Colorectal Cancer AJCC v8 | 12/23 | 12/23 | | |
ChiCTR2000028961: Combination of high-throughput sequencing and primary cell culture as an exploratory study of individualized treatment of malignant tumors: phase 2 clinical trial of sintilimab for retroperitoneal dedifferentiation of liposarcoma |
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| Not yet recruiting | N/A | 30 | | Neoadjuvant sintilimab monotherapy ;Neoadjuvant sintilimab combined with epirubicin and/or ifosfamide | Department of Urology, Shanghai Changhai Hospital, the Second Military Medical University, Shanghai, China; Second Military Medical University, Innovent Biologics, Inc. | retroperitoneal dedifferentiated liposarcoma | | | | |
NCT04553744: Identification of Surgical Management of Lymph Node Basins and Surgical Practice Patterns Among Sarcoma Surgeons |
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| Withdrawn | N/A | 5000 | NA | Survey Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Soft Tissue Sarcoma, Lymph Node Cancer | 02/24 | 02/24 | | |
