| Sarcoma |
| Recruiting | N/A | 20 | | high-intensity focused ultrasound (HIFU) | Childrens Hospital of Chongqing Medical University; None, National Clinical Key Subject Construction Project([2013]544) | Osteosarcoma | | | | |
ChiCTR2000037773: Safety of intraoperative autologous blood transfusion in patients with osteosarcoma |
|
|
| Completed | N/A | 30 | | Autogenous blood | Beijing Jishuitan Hospital; Beijing Jishuitan Hospital, Scientific research funds of the department | osteosarcoma | | | | |
ChiCTR1900020854: Relationship between changes of blood drug concentration and therapeutic effect in preoperative imatinib (IM) treatment of malignant gastrointestinal stromal tumor (GIST) |
|
|
| Recruiting | N/A | 24 | | Increase the dose of imatinib | West China Hospital, Sichuan University; West China Hospital, Sichuan University, National Natural Science Foundation of China and postgraduate funds of West China Clinical Medical College of Sichuan University | GISTs | | | | |
NCT03358628: Patient-derived Xenograft (PDX) Modeling to Test Drug Response for High-grade Osteosarcoma |
|
|
| Not yet recruiting | N/A | 20 | NA | Molecular Profiling & In Vivo drug testing in PDX | Peking University People's Hospital | Osteosarcoma | 01/20 | 01/25 | | |
NCT03360760: Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum |
|
|
| Recruiting | N/A | 100 | RoW | Doxorubicin, Adriamycin, Cisplatin, cisplatinum, platamin, Methotrexate, HD-MTX, Ifosfamide, ifosphamide, definitive surgery, pre surgical chemotherapy, neoadjuvant chemotherapy | Peking University People's Hospital | Osteosarcoma of Pelvis | 02/20 | 02/25 | | |
ChiCTR1900028480: Clinical outcomes of different therapeutic modalities for rectal gastrointestinal stromal tumor: summary of 14-year clinical experience in a single center |
|
|
| Recruiting | N/A | 71 | | surgery | Department of General Surgery, Zhongshan Hospital, Fudan University School of Medicine; Zhongshan Hospital Affiliated to Fudan University, National Natural Science Foundation of China (81773080) | rectal gastrointestinal stromal tumor | | | | |
NCT04225429: Tazemetostat Expanded Access Program for Adults With Epithelioid Sarcoma |
|
|
| No Longer Available | N/A | | NA | Tazemetostat | Epizyme, Inc., WEP Clinical | Epithelioid Sarcoma | | | | |
ChiCTR1900028412: Indeterminate Pulmonary Nodules Affect the Survival of Patients with Non-metastatic, High-grade, Localized Osteosarcome: medical records based retrospective study |
|
|
| Recruiting | N/A | 500 | | Nil ;Nil | Shanghai Jiaotong University Affiliated Sixth People's Hospital; Department of Oncology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, no funds | ostrosarcoma | | | | |
ChiCTR1900028434: Indeterminate Pulmonary Nodules Affect the Survival of Patients with Non-metastatic, High-grade, Localized Osteosarcome: a medical records based Retrospective Cohort Study |
|
|
| Recruiting | N/A | 400 | | Nil | Shanghai Jiaotong University Affiliated Sixth People's Hospital; Department of Oncology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, no funds | ostrosarcoma | | | | |
ChiCTR1900026030: Ki-67 labelling index is related to the risk classification and prognosis of gastrointestinal stromal tumours: a retrospective study |
|
|
| Not yet recruiting | N/A | 204 | | N/A | Zhongnan Hospital of Wuhan University; Zhongnan Hospital of Wuhan University, Health Commission of Hubei Province | Gastrointestinal stromal tumours | | | | |
ChiCTR2000033799: ANALYSIS OF PROGNOSTIC FACTORS IN SOFT TISSUE SARCOMA: CANCER REGISTRY FROM A SINGLE TERTIARY HOSPITAL IN INDONESIA |
|
|
| Completed | N/A | 106 | | None | Dr. Soetomo General Hospital; Level of the institution：, None | Soft Tissue Sarcoma | | | | |
ChiCTR1900026073: Factors influencing the efficacy of daily repeated ultrasound-guided high intensity focused ultrasound treatment of desmoid tumors: early clinical experiences. |
|
|
| Not yet recruiting | N/A | 10 | | HIFU therapy | The Sixth People's Hospital affiliated to Shanghai Jiaotong University; The Sixth People's Hospital affiliated to Shanghai Jiaotong University, NA | desmoid tumors | | | | |
ChiCTR1900021945: A randomized cross-over controlled trial for comparing efficacy and safety of PEG-rhG-CSF versus rhG-CSF in the prevention of chemotherapy-induced neutropenia in sarcoma patients with doxorubicin + isocyclophosphamide treatment |
|
|
| Not yet recruiting | N/A | 78 | | cycle 1: PEG-rhG-CSF 100μg/kg, once; cycle 2: rhG-CSF 5μg/kg/d, daily up to ANC≥2×10^9/L ;cycle 1: rhG-CSF 5μg/kg/d, daily up to ANC≥2×10^9/L; cycle 2: PEG-rhG-CSF 100μg/kg, once. | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Chinese Society of Clinical Oncology | sarcoma | | | | |
| Not yet recruiting | N/A | 800 | | Nil | Affiliated Sixth People's Hospital, Shanghai Jiaotong University; Affiliated Sixth People’s Hospital, Shanghai Jiaotong University, People’s Republic of China, None | bone tumor | | | | |
| Recruiting | N/A | 200 | | NA | Shanghai Changzheng Hospital; Shanghai Changzheng Hospital, Grants for Scientific Research | osteosarcoma | | | | |
| Recruiting | N/A | 200 | | NA | Shanghai Changzheng Hospital; Shanghai Changzheng Hospital, Grants for Scientific Research | Ewing's sarcoma | | | | |
| Recruiting | N/A | 200 | | NA | Shanghai Changzheng Hospital; Shanghai Changzheng Hospital, Grants for Scientific Research | chondrosarcoma | | | | |
| Recruiting | N/A | 2000 | Canada, US, Europe, RoW | | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, TransAtlantic Retroperitoneal Sarcoma Working Group | Retroperitoneal Sarcoma | 12/20 | 12/30 | | |
ChiCTR1800020096: A prospective, multi-center, single-arm clinical study for the efficacy and safety of dasatinib in the treatment of patients with unsuccessful imatinib desmoid tumor therapy. |
|
|
| Not yet recruiting | N/A | 51 | | pharmacotherapy 50mg/2 times/d | Peking University Cancer Hospital; Peking University Cancer Hospital, ChiaTai Tian Qqing Pharmaceutical Group Co., Ltd.(CTTQ) | Desmoid Tumor | | | | |
ChiCTR2000029130: The rehabilitation effect and mechanism of dorsolateral prefrontal cortex (DLPFC) stimulation on bone cancer pain |
|
|
| Recruiting | N/A | 90 | | rTMS treatment ;Placebo ;Conventional treatment | ChongQing University Cancer Hospital; ChongQing University Cancer Hospital, National Natural Science Foundation of China | bone cancer | | | | |
NCT06291662: Evaluation of Performance Characteristics and Applicability in Oncology of Devices Customized Medical Devices Made by 3D Printing |
|
|
| Recruiting | N/A | 12 | Europe | 3D printer applications | Kathleen McGreevy | Sarcoma, Intracranial Neoplasm, Pelvic Bone Neoplasm | 12/24 | 06/25 | | |
ChiCTR-TRC-14004094: Feasibility and safety of resection of small gastric gastrointestinal stromal tumor: a randomized controlled clinical trial |
|
|
| Recruiting | N/A | 150 | | No intervention ;Endoscopic resection ;Surgical resection | Department of Digestive Surgery, the First Affiliated Hospital (Xijing Hospital), the Fourth Military Medical University; Level of the institution：, The scientific research foundation of our department supported by Xijing Hospital | gastrointestinal stromal tumor (GIST) | | | | |
NCT03362086: The Osteosarcoma Biobank in Peking University People's Hospital |
|
|
| Not yet recruiting | N/A | 180 | NA | | Peking University People's Hospital | Osteosarcoma | 02/21 | 02/24 | | |
NCT04289077: Quality of Life of Patients With Desmoid-type Fibromatosis |
|
|
| Completed | N/A | 156 | Europe | Questionnaires | Erasmus Medical Center, Radboud University Medical Center, The Netherlands Cancer Institute, Royal Marsden NHS Foundation Trust | Desmoid Tumor, Desmoid-type Fibromatosis | 02/21 | 02/21 | | |
NCT04518488: Prehabilitation Soft-Tissue Sarcoma of Lower Limb |
|
|
| Not yet recruiting | N/A | 30 | NA | Exercises, Informational Support Group (Control group) | McGill University | Soft Tissue Sarcoma | 02/21 | 09/21 | | |
ChiCTR2000033807: Transcriptome Profiling of Peripheral Blood Cells in Patients With Metastatic Bone Pain Base on RNA-Seq Technique |
|
|
| Not yet recruiting | N/A | 30 | | N/A | Department of Anesthesiology, the First Affiliated Hospital of Sun Yat-Sen University; The First Aflliated Hospital of Sun Yat-Sen University, own expense | bone cancer pain | | | | |
ChiCTR2000039898: Pain management in patients with metastatic bone cancer based on the theory of 'wrist-ankle acupuncture': study protocol for a randomized controlled trial |
|
|
| Recruiting | N/A | 82 | | Pain management intervention of integrated traditional Chinese and western medicine based on wrist-ankle acupuncture ;Routine care of patients with metastatic bone cancer | Affiliated Hospital of Chengdu University of TCM; Affiliated Hospital of Chengdu University of TCM, Project funding | metastatic bone cancer | | | | |
| Not yet recruiting | N/A | 150 | | adjuvant chemotherapy | Beijing Jishuitan Hospital; Beijing Jishuitan Hospital, none | Osteosarcoma | | | | |
ChiCTR1800020473: The current status of treatment for gastrointestinal stromal tumors in the real word |
|
|
| Recruiting | N/A | 1000 | | Case series | West China Hospital, Sichuan University; West China Hospital, Sichuan University, Beijing medical and health foundation | Gastrointestinal stromal tumors | | | | |
NCT04055753: Study to Assess TOPO2A as a Biomarker for Sensitivity to Doxorubicin/Doxil in Soft Tissue Sarcoma |
|
|
| Active, not recruiting | N/A | 24 | US | Doxil, Doxorubicin | Fox Chase Cancer Center | Soft Tissue Sarcoma | 06/21 | 05/24 | | |
ChiCTR1800017855: Treating osteosarcoma: developing a biobank and Wnt inhibition therapeutics |
|
|
| Recruiting | N/A | 200 | | Patient derived organoid culture | Shanghai Sixth People's Hospital; Shanghai Sixth People's Hospital, St. Baldrick's Foundation | Osteosarcoma | | | | |
NCT04651569: An Analysis of the Efficacy of High Dose Isofosfamide Through Elastomer |
|
|
| Completed | N/A | 26 | Europe | Observational study | Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna | Osteosarcoma Recurrent | 06/21 | 12/22 | | |
NCT05100368: The Prognostic Value of Serum Biomarkers in Ewing's Sarcoma |
|
|
| Completed | N/A | 1000 | Europe | patients | Istituto Ortopedico Rizzoli | Sarcoma, Ewing | 07/21 | 07/21 | | |
NCT06385288: Blood and Tissue Extraction for Immunological Examinations During Neoadjuvant Therapy of Soft Tissue Sarcomas |
|
|
| Recruiting | N/A | 30 | Europe | Blood and tissue collection for immunological studies, advanced imaging., neoadjuvant Therapy | University Hospital Tuebingen | Soft Tissue Sarcoma Adult | 07/26 | 07/31 | | |
ChiCTR1800018262: Curcumin inhibits proliferation and invasion of MG63 cells through inactivation of pJAK-2/pSTAT-3 pathway |
|
|
| Not yet recruiting | N/A | 300 | | curcumin | Affiliated Sixth People's Hospital, Shanghai Jiaotong University; Affiliated Sixth People's Hospital, Shanghai Jiaotong University, Affiliated Sixth People's Hospital, Shanghai Jiaotong University | Osteosarcoma | | | | |
ChiCTR1900024967: Amroitinib hydrochloride combined with AI (doxorubicin + ifosfamide) for the treatment of high-grade soft tissue sarcomas with difficult surgical resection: a prospective, single arm, multi-center clinical study |
|
|
| Recruiting | N/A | 78 | | Amroitinib hydrochloride | Beijing Jishuitan Hospital; Xijing Hospital, Military Medical University of The Air Force; Beijing Jishuitan Hospital, CHIATAI TIANQING | soft tissue sarcoma | | | | |
ChiCTR2000031226: An open, single arm and early clinical study of TAEST16001 in the treatment of solid tumor mainly containing soft tissue sarcoma with positive expression of tumor antigen NY-ESO-1 (HLA-A * 02:01) |
|
|
| Recruiting | N/A | 12 | | TAEST16001 cells treat tumor antigen NY-ESO-1 | Sun Yat-Sen University Cancer center; Sun Yat-Sen University Cancer Center, Guangdong Xiangxue Precision Medical Technology Co., Ltd. | soft tissue sarcoma | | | | |
ChiCTR1900025515: To explore the efficacy of MASCT-I combined with PD1 antibody and apatinib mesylate in the treatment of advanced osteosarcoma and soft tissue sarcoma. |
|
|
| Not yet recruiting | N/A | 20 | | MASCT-I A+PD1 antibody+Apatinib ;MASCT-I B+PD1 antibody+Apatinib | Shanghai Sixth People's Hospital; HRYZ (ShenZhen) Biotech Co., HRYZ (ShenZhen) Biotech Co. | Advanced Osteosarcoma and Soft Tissue Sarcoma | | | | |
NCT06202599: Fruquintinib-based Treatment for Refractory Bone and Soft Tissue Sarcomas After Several Lines of TKIs' Resistance |
|
|
| Completed | N/A | 124 | RoW | Fruquintinib | Peking University People's Hospital | Bone Sarcoma, Soft Tissue Sarcoma, Refractory Tumor | 08/23 | 11/23 | | |
NCT03154190: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer |
|
|
| Active, not recruiting | N/A | 128 | US | Best Practice, standard of care, standard therapy, Laboratory Biomarker Analysis, Supportive Care, Supportive Therapy, Symptom Management, Therapy, Supportive, Survey Administration | Stanford University | Acute Myeloid Leukemia, Brain Glioblastoma, Estrogen Receptor Negative, Extensive Stage Small Cell Lung Carcinoma, Head and Neck Carcinoma, HER2/Neu Negative, Hormone-Resistant Prostate Cancer, Limited Stage Small Cell Lung Carcinoma, Myelodysplastic Syndrome, Progesterone Receptor Negative, Progressive Disease, Recurrent Carcinoma, Stage II Pancreatic Cancer, Stage II Rectal Cancer, Stage IIA Pancreatic Cancer, Stage IIA Rectal Cancer, Stage IIB Pancreatic Cancer, Stage IIB Rectal Cancer, Stage IIC Rectal Cancer, Stage III Colon Cancer, Stage III Esophageal Cancer, Stage III Gastric Cancer, Stage III Non-Small Cell Lung Cancer, Stage III Ovarian Cancer, Stage III Pancreatic Cancer, Stage III Rectal Cancer, Stage III Skin Melanoma, Stage IIIA Colon Cancer, Stage IIIA Esophageal Cancer, Stage IIIA Gastric Cancer, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIA Ovarian Cancer, Stage IIIA Rectal Cancer, Stage IIIA Skin Melanoma, Stage IIIB Colon Cancer, Stage IIIB Esophageal Cancer, Stage IIIB Gastric Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Rectal Cancer, Stage IIIB Skin Melanoma, Stage IIIC Colon Cancer, Stage IIIC Esophageal Cancer, Stage IIIC Gastric Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Rectal Cancer, Stage IIIC Skin Melanoma, Stage IV Bladder Cancer, Stage IV Bone Sarcoma, Stage IV Breast Cancer, Stage IV Colon Cancer, Stage IV Esophageal Cancer, Stage IV Gastric Cancer, Stage IV Non-Small Cell Lung Cancer, Stage IV Ovarian Cancer, Stage IV Pancreatic Cancer, Stage IV Rectal Cancer, Stage IV Renal Cell Cancer, Stage IV Skin Melanoma, Stage IV Soft Tissue Sarcoma, Stage IVA Bone Sarcoma, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Bone Sarcoma, Stage IVB Colon Cancer, Stage IVB Rectal Cancer, Triple-Negative Breast Carcinoma | 11/21 | 08/22 | | |
NCT04619030: Augmented Reality (AR): The Future of "Patient Information Leaflets |
|
|
| Recruiting | N/A | 20 | Europe | Augmented Reality, Traditional leaflet | NHS Greater Glasgow and Clyde, The Glasgow School of Art | Sarcoma, Breast Cancer, Cleft Lip and Palate, Surgical Flap | 12/21 | 03/22 | | |
| Recruiting | N/A | 60 | | Local and Intratumoral Administration ;intravenous therapy | Xuzhou Cancer Hospital; Guangzhou Sinogen Pharmaceutical Co.Ltd, Self-financing | Advanced malignant tumors including, but not limited to, pancreatic cancer, colorectal cancer, liver cancer, gastric cancer, non-small cell lung cancer, breast cancer, sarcoma etc. | | | | |
ChiCTR1800020459: Effectiveness of neuromuscular electrical stimulation for postoperative pain in patients with osteosarcoma after surgery |
|
|
| Not yet recruiting | N/A | 72 | | Sham stimulating ;neuromuscular electrical stimulation | First Affiliated Hospital of Jiamusi University; First Affiliated Hospital of Jiamusi University, First Affiliated Hospital of Jiamusi University | osteosarcoma | | | | |
ChiCTR1800020399: Effectiveness of electroacupuncture for phantom limb pain in patients with osteosarcoma after surgery |
|
|
| Not yet recruiting | N/A | 96 | | EA treatment ;Sham EA treatment | First Affiliated Hospital of Jiamusi University; First Affiliated Hospital of Jiamusi University, First Affiliated Hospital of Jiamusi University | osteosarcoma | | | | |
ChiCTR1900025163: Genomic profiling analysis of clinical sarcomas: a multicenter, non-randomized, open and authentic study |
|
|
| Recruiting | N/A | | | | The First Affiliated Hospital, Sun Yat-Sen University; The First Affiliated Hospital, Sun Yat-Sen University, No funds | Sarcoma | | | | |
ChiCTR2000041209: An observational study on the correlation between C-MET expression and clinical prognosis of osteosarcoma |
|
|
| Recruiting | N/A | 30 | | Nil | Shanghai General Hospital; Shanghai General Hospital, Project funding | osteosarcoma | | | | |
BIOPSAR, NCT04250766: Diagnostic Performances of Preoperative Echo-guided Uterine Biopsy in the Management of Suspect Uterine Sarcoma Tumors |
|
|
| Not yet recruiting | N/A | 275 | Europe | Echo-guided uterine biopsy | Institut Bergonié, GIRCI SOHO | Fibroid Uterus, Sarcoma Uterus | 01/22 | 01/25 | | |
| Completed | N/A | 2353 | Europe | Ultrasound, MRI | Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Prof. Antonia Testa, Dr. Daniela Romualdi, Dr. Francesca Ciccarone | Sarcoma Uterus | 12/23 | 12/23 | | |
| Recruiting | N/A | 70 | Europe | | University of Copenhagen, The Novo Nordic Foundation | Pain, Bone Metastases, Metastatic Breast Cancer | 02/22 | 02/23 | | |
| Recruiting | N/A | 120 | Europe | CTC isolation by HSP70 | Charite University, Berlin, Germany, Klinikum rechts der Isar, TU München, (TUM), Munich, Germany. | Melanoma Stage IV, Sarcoma, Squamous Cell Carcinoma, Pancreatic Cancer Stage IV, Prostate Cancer, Breast Cancer Stage IV | 02/22 | 05/22 | | |
NCT04757064: Efficacy of Exercise Program on Osteosarcoma Patients |
|
|
| Not yet recruiting | N/A | 40 | NA | standard rehabilitation protocol | Cairo University | Osteosarcoma | 02/22 | 04/22 | | |
NCT03792867: Radical Resection and HIPEC for Recurrent Retroperitoneal Sarcoma |
|
|
| Active, not recruiting | N/A | 5 | RoW | Doxorubicin | National Cancer Centre, Singapore | Retroperitoneal Sarcoma | 02/22 | 03/24 | | |
NCT04893356: Impact of O6-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation and MGMT Expression on Dacarbazine Treated Sarcoma Patients (MGMT) |
|
|
| Active, not recruiting | N/A | 75 | Europe | O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and MGMT expression on dacarbazine treated sarcoma patients | National Cancer Institute, Naples | Sarcoma | 02/22 | 01/25 | | |
| Recruiting | N/A | 600 | RoW | FGFR Inhibitor, IDH1 Inhibitor, HER2 Inhibitor, PARP Inhibitor, BRAF Inhibitor, MEK Inhibitor, ICIs, EGFR-TKIs, NTRK-TKI, and et. al., Targeted Agent, Other Therapy, Other Drugs | Peking University, Hangzhou DIAN Medical Diagnostic Center Co., Ltd., China | Biliary Tract Neoplasms, Gastric Cancer, Esophageal Squamous Cell Carcinoma, Colorectal Cancer, Gastrointestinal Stromal Tumors, Pancreatic Cancer, Neuroendocrine Tumors, Unknown Primary Cancer, Digestive Cancer | 02/24 | 02/24 | | |
| Recruiting | N/A | 50 | US | Biospecimen sample collection during standard-of-care surgery | Fox Chase Cancer Center | Retroperitoneal Liposarcoma, Soft Tissue Sarcoma | 06/27 | 08/27 | | |
SARCOLD, NCT03077178: Impact of Locoregional Treatment of Soft Tissue Sarcoma on Status of Patients Aged 70 Years and Over |
|
|
| Recruiting | N/A | 100 | Europe | Geriatric assessment | Institut Bergonié, Ministry of Health, France | Soft Tissue Sarcoma Adult | 03/22 | 03/23 | | |
ChiCTR2100045408: The effect of the time of imatinib treatment on the recurrence of patients with gastrointestinal stromal tumor |
|
|
| Recruiting | N/A | 500 | | Null | Sichuan University; West China Hospital Sichuan University, None | Gastrointestinal stromal tumors | | | | |
ETIOSARC, NCT03670927: Etiosarc: Environmental Aetiology of Sarcomas From a Multicenter French Population-based Case-control Study Among Adults |
|
|
| Recruiting | N/A | 6462 | Europe | Environmental, occupational and lifestyle-related exposures | Institut National de la Santé Et de la Recherche Médicale, France | Sarcoma, Environmental Exposure, Occupational Exposure, Life Style | 04/22 | 04/22 | | |
NCT02634710: Hypofractionated Pre-operative Radiation Therapy for Soft Tissue Sarcomas of the Extremity and Chest-wall |
|
|
| Active, not recruiting | N/A | 35 | US | Hypofractionated Radiation Therapy | Medical College of Wisconsin | Soft Tissue Sarcoma | 05/22 | 12/24 | | |
IOPN, NCT03655587: Impact of an Orthotic Intervention in Children With Peripheral Neuropathy |
|
|
| Completed | N/A | 27 | US | Solid ankle foot orthotic, Resting night splint | Children's Hospitals and Clinics of Minnesota, Pine Tree Apple Tennis Classic Foundation, St. Jude Children's Research Hospital | Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy, Acute Lymphocytic Leukemia, Pediatric, Rhabdomyosarcoma, Wilms Tumor | 05/22 | 05/22 | | |
NCT04327908: Translation and Validation of the German Version of the Toronto Extremity Salvage Score (TESS) and Musculoskeletal Tumor Society (MSTS) |
|
|
| Not yet recruiting | N/A | 250 | NA | Questionaire TESS and MSTS | Medical University Innsbruck | Sarcoma | 06/22 | 06/23 | | |
ChiCTR2000035867: Human 13 gene mutation analysis software complements clinical trials |
|
|
| Not yet recruiting | N/A | | | | Shanghai Chest Hospital; Guangzhou Burning Rock Dx Co., Ltd, Guangzhou Burning Rock Dx Co., Ltd | Non-small cell lung cancer (NSCLC), colorectal cancer (CRC) , gastrointestinal stromal tumor (GIST) | | | | |
ChiCTR2000036422: The combination human 13 gene mutation Detection kit (reversible terminal termination sequencing) complements the clinical trial |
|
|
| Not yet recruiting | N/A | 30000 | | Lianhua Qingwen Capsules 4 capsules/time or Lianhua Qingwen Granules 1 bag/time, 3 times a day ;Do not give Lianhua Qingwen | Shanghai Chest Hospital; Guangzhou Burning Rock Dx Co., Ltd, Guangzhou Burning Rock Dx Co., Ltd | non-small cell lung cancer (NSCLC), colorectal cancer (CRC) , gastrointestinal stromal tumor (GIST) | | | | |
MYOSARC, NCT04214457: Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and Leiomyosarcomas |
|
|
| Recruiting | N/A | 1000 | Europe | Biopsy and peripheral blood collection | Igenomix | Leiomyoma, Leiomyosarcoma | 07/22 | 07/22 | | |
NCT04330456: Combined Treatment of Patients With Soft Tissue Sarcoma Including Preoperative Stereotactic Radiation Therapy and Postoperative Conformal Radiation Therapy |
|
|
| Recruiting | N/A | 30 | RoW | Preoperative stereotactic radiation therapy in hypofractionation mode, Surgery, Postoperative conformal radiation therapy in normofractionation mode | N.N. Petrov National Medical Research Center of Oncology | Soft Tissue Sarcoma Adult | 07/22 | 07/28 | | |
NCT04604158: Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients |
|
|
| Completed | N/A | 38 | US | Elly Mobile Phone Application, Elly App | Gillian Gresham | Cancer, Cancer Metastatic, Neoplasms, Breast Cancer, Lung Cancer, Glioblastoma, Prostate Cancer, Gynecologic Cancer, Colorectal Cancer, Sarcoma, Kidney Cancer, Bladder Cancer, Lymphoma, Leukemia, Head and Neck Cancer, Pancreas Cancer, Multiple Myeloma, Anxiety, Social Isolation, Stress, Loneliness, Melanoma, Uterine Cancer | 05/24 | 05/24 | | |
| Completed | N/A | 37 | US | Oncolo-GIST, Usual Care Arm | Weill Medical College of Cornell University, National Institute of Nursing Research (NINR) | Critical Illness, Oncology, Communication | 07/22 | 01/23 | | |
NCT03515174: Trial Comparing Active Intervention At Diagnosis With Usual Care to Improve Psycho-social Care in AYAO |
|
|
| Active, not recruiting | N/A | 70 | RoW | Supportive Care Program, Usual Care | National Cancer Centre, Singapore | Carcinoma, Lymphoma, Sarcoma, Cancer | 07/22 | 04/24 | | |
ESWT, NCT05801887: Extracorporeal Shock Wave Therapy on Osteoblast-Like Cells In- Vitro Study |
|
|
| Completed | N/A | 20 | RoW | Extracorporeal shockwave device, ESWT, No ESWT, shockwave | Krishnadevaraya College of Dental Sciences & Hospital | Osteosarcoma | 08/22 | 11/22 | | |
NCT04945512: Efficacy of Epidural Analgesia in Lower Extremity Osteosarcoma |
|
|
| Recruiting | N/A | 28 | RoW | Epidural Analgesia | Istanbul University | Osteosarcoma, Analgesia | 08/22 | 09/22 | | |
NCT03493165: Expanded Access to Everolimus, for an Individual Patient With Uterine Sarcoma (CTMS#18-0020) |
|
|
| Available | N/A | | NA | Everolimus, Zortress, Afinitor, and Afinitor Disperz | The University of Texas Health Science Center at San Antonio | Uterine Sarcoma | | | | |
| Completed | N/A | 68 | Europe | Non-Interventional | Martin-Luther-Universität Halle-Wittenberg | Leukemia, Brain Tumor, Sarcoma, Childhood Cancer, Cancer, Adolescent Cancer | 07/23 | 12/23 | | |
ChiCTR2000032694: Clinical study for combined chemotherapy with arsenic trioxide for stage III osteosarcoma |
|
|
| Not yet recruiting | N/A | 40 | | N/A | The First Affiliated Hospital of Sun Yat-Sen University; The First Affiliated Hospital of Sun Yat-Sen University, Applied research fund | Osteosarcoma | | | | |
NCT04553471: Palliative Lattice Stereotactic Body Radiotherapy (SBRT) for Patients With Sarcoma, Thoracic, Abdominal, and Pelvic Cancers |
|
|
| Completed | N/A | 70 | US | Stereotactic body radiotherapy, SBRT, Research blood draw | Washington University School of Medicine, Goldman Sachs Foundation (Emerson Collective) | Sarcoma, Thoracic Cancer, Abdominal Cancer, Pelvic Cancer | 09/22 | 05/23 | | |
ChiCTR2000037499: Unexpected Surgery affect the clearance rate of Mohs Microscopic Surgery in Dermatofibrosarcoma Protuberans: A Prospective Cohort Study |
|
|
| Not yet recruiting | N/A | 60 | | None ;None | Shanghai Ninth People's Hospital, Affiliated to Shanghai Jiaotong University School of Medicine; Shanghai Ninth People's Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Clinical Research Project of Multi-Disciplinary Team, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine | Dermatofibrosarcoma Protuberans | | | | |
ChiCTR2000036952: Clinical outcomes of abdominal wall repair after curative resection of primary retroperitoneal liposarcoma using biomaterial patches |
|
|
| Recruiting | N/A | 30 | | Medical collagen patch ;Surgisis patches | Shanghai Public Health Clinical Center; Shanghai Public Health Clinical Center, Promoting clinical skills and clinical innovation in municipal hospitals Three-year action plan 2020-2022) Major clinical research projects | retroperitoneal liposarcoma | | | | |
ChiCTR2000037308: Molecular detection as an companion diagnostics and prognostic marker of therapeutic efficacy of targeted/immunotherapy for pediatric soft tissue sarcoma |
|
|
| Recruiting | N/A | 200 | | Nil | Xinhua Hospital, School of Medicine, Shanghai Jiaotong University; Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Hospital development center | pediatric soft tissue sarcoma | | | | |
ChiCTR2000036569: FAPI PET/CT guided dose optimization and translational study for bone and soft tissue sarcoma |
|
|
| Recruiting | N/A | 30 | | carbon ion | Shanghai Proton and Heavy ion Center; Shanghai Proton and Heavy ion Center, self-raised | soft tissue sarcoma | | | | |
ChiCTR1900026540: Individualized treatment and clinical validation of osteosarcoma based on MiniPDX susceptibility test |
|
|
| Not yet recruiting | N/A | 20 | | Establishment of PDX model and MiniPDX susceptibility test using tumor specimens | First Affiliated Hospital of the Fourth Military Medical University; First Affiliated Hospital of the Fourth Military Medical University, Self-raising | Osteosarcoma | | | | |
| Recruiting | N/A | 53 | RoW | Preventive photobiomodulation Therapy (PBMT), Preventive Low Power Laser Therapy (TLBP ) | Instituto Nacional de Cancer, Brazil | Mucositis Oral | 06/25 | 07/25 | | |
| Recruiting | N/A | 450 | Europe | Paraffin tissue samples, blood sample | Institut du Cancer de Montpellier - Val d'Aurelle | Sarcoma | 11/22 | 11/27 | | |
ChiCTR2000038923: A clinical study on the influence of expressive writing on the mental state and quality of life of cancer patients and their families |
|
|
| Recruiting | N/A | 248 | | Expressive writing ;Tumor fact writing ;Neutral writing ;Expressive writing ;Expressive writing ;Neutral writing | West China Hospital of Sichuan University; West China Hospital of Sichuan University, self-raised | Soft tissue sarcoma, malignant melanoma, nasopharyngeal carcinoma | | | | |
NCT05612191: Catequentinib in Patients Who Have Completed an Advenchen Study (A Compassionate Use Trial) |
|
|
| Available | N/A | | NA | AL3818, Catequentinib (AL3818, Anlotinib) Hydrochloride | Advenchen Laboratories, LLC | Sarcoma,Soft Tissue, Gynecologic Cancer | | | | |
| Recruiting | N/A | 31095 | | No | Tongji Hospital; Tongji Hospital, The Fundamental Research Funds for the Central Universities (HSUT: 2021yjsCXCY087) | Extremity Bone and Soft Tissue Sarcomas | | | | |
NCT03298971: The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors |
|
|
| Recruiting | N/A | 240 | RoW | Questionnaires | The University of Hong Kong | Childhood Osteosarcoma | 12/22 | 12/22 | | |
ChiCTR-OOC-17013435: Clinical Research of radiotherapy combined with apatinib mesylate tablets in the treatment of residual, recurrent and metastatic sarcoma |
|
|
| Recruiting | N/A | 50 | | radiotherapy combined with apatinib | The First Hospital of Jilin University; The First Hospital of Jilin University, Self-financing | sarcoma | | | | |
RMS-AJA-1701, NCT03462888: Clinico-biological Study/Characterization of Rhabdomyosarcoma in Adolescents and Young Adults, 15-25-year-old Patients |
|
|
| Active, not recruiting | N/A | 113 | Europe | | Centre Oscar Lambret, Centre Leon Berard, Société Française de lutte contre les Cancers et les leucémies de l'Enfant et l'adolescent, French Sarcoma Group, Ligue contre le cancer, France | Rhabdomyosarcoma | 12/24 | 12/24 | | |
EmutRAS, NCT03908788: Detection of the Emergence of RAS (Rat Sarcoma Viral Oncogene Homolog) Mutations in Circulating DNA (Deoxyribonucleic Acid) in Patients With mCRC (Metastatic Colorectal Cancer) During Treatment With Anti-EGFR (Epidermal Growth Factor Receptor) Therapy |
|
|
| Active, not recruiting | N/A | 130 | Europe | Intplex test | Institut du Cancer de Montpellier - Val d'Aurelle | Metastatic Colorectal Cancer | 03/25 | 10/25 | | |
NCT04991883: Analysis of the Molecular Profile of the Mixofibrosarcoma of the Extremities |
|
|
| Completed | N/A | 167 | Europe | case series review of clinical and histological data | Istituto Ortopedico Rizzoli | Sarcoma,Soft Tissue | 12/22 | 12/22 | | |
NCT06038552: The Long-term Efficacy of Imatinib With Hepatic Resection or Other Local Treatment for GIST Liver Metastases |
|
|
| Completed | N/A | 238 | RoW | imatinib (IM), Gleevec, hepatic resection (HR), radiofrequency ablation (RFA), transarterial chemoembolization (TACE) | First Affiliated Hospital, Sun Yat-Sen University | GIST, Malignant, Liver Metastases | 12/22 | 05/23 | | |
HEART, NCT01790152: Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment |
|
|
| Recruiting | N/A | 420 | Canada, US, RoW | Assessment of Therapy Complications, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration | Children's Oncology Group, National Cancer Institute (NCI) | Hodgkin Lymphoma in Remission, Leukemia in Remission, Lymphoblastic Lymphoma, Osteosarcoma, Recurrent Leukemia, Recurrent Lymphoma, Recurrent Malignant Neoplasm | 12/22 | 12/25 | | |
NCT03296371: Genetic Mutational Analysis of Saliva or Buccal Mucosa Samples From Patients With Embryonal or Alveolar Rhabdomyosarcoma |
|
|
| Active, not recruiting | N/A | 900 | US | Biospecimen Collection, Laboratory Biomarker Analysis, Questionnaire Administration | Children's Oncology Group, National Cancer Institute (NCI) | Alveolar Rhabdomyosarcoma, Embryonal Rhabdomyosarcoma | 12/22 | 12/24 | | |
ChiCTR1900024156: The proteomics of rhabdomyosarcoma in children and adolescents: Identification of a protein biomarkers |
|
|
| Recruiting | N/A | | | | Beijing Children′s Hospital, Capital Medical University; Beijing Children′s Hospital, Capital Medical University, Researcher self-raising | Rhabdomyosarcoma | | | | |
NCT04293289: Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma |
|
|
| Completed | N/A | 10 | Japan | CICS-1 (investigational device),SPM-011(investigational drug) | Cancer Intelligence Care Systems, Inc., Stella Pharma Corporation | Malignant Melanoma, Angiosarcoma | 12/22 | 12/22 | | |
| Completed | N/A | 14 | US | | Florida International University, Nicklaus Children's Hospital f/k/a Miami Children's Hospital, Cornelia T. Bailey Foundation | Ewing Sarcoma, Osteosarcoma, Rhabdomyosarcoma, Wilms Tumor, Sarcoma, Spindle Cell, Sarcoma Rhabdoid, Childhood Sarcoma of Soft Tissue | 12/22 | 12/22 | | |
ChiCTR2000029913: Role of surgery in patients with focally progressive GISTs after imatinib treatment: a prospective, multicenter, registration study |
|
|
| Recruiting | N/A | 122 | | Surgery + Imatinib400mg/d ;imatinib 600mg/d or sunitinib 37.5mg/d | Zhongshan Hospital affiliated to Fudan University; Zhongshan hospital affiliated to fudan university, National natural science foundation of China (81773080) | Gastrointestinal stromal tumor | | | | |
ChiCTR2100042550: Endoscopy Excision of Gastric Interstitialomas By Super Forward-return Way |
|
|
| Recruiting | N/A | 100 | | Nil | The Fourth Affiliated Hospital of China Medical University; The Fourth Affiliated Hospital of China Medical University, Self-financing | Gastrointestinal Stromal Tumor | | | | |
ChiCTR2100053594: Efficacy and safety of eribulin monotherapy or combination therapy in Chinese adults with soft tissue sarcoma |
|
|
| Not yet recruiting | N/A | | | Anthracycline-based drugs ;Ifosfamide-based ;Other chemotherapy options ;Combined molecular targeted therapy ;Combination immune checkpoint inhibitor therapy | Zhongshan Hospital, Fudan University; Zhongshan Hospital, Fudan University, self-funded | soft tissue sarcoma (STS) | | | | |
ChiCTR2200060324: A retrospective clinical study of patients with esophageal sarcomatoid carcinoma |
|
|
| Not yet recruiting | N/A | | | | West China Hospital, Sichuan University; West China Hospital, Sichuan University, SCI funding projects of the study leader | Esophageal sarcomatoid carcinoma | | | | |
ChiCTR2200066276: Aggressive surgical approach with major vascular resection for retroperitoneal sarcomas |
|
|
| Not yet recruiting | N/A | 252 | | N/A ;N/A | West China Hospital, Sichuan University; West China Hospital, Sichuan University, None | Retroperitoneal sarcomas | | | | |
