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| Not yet recruiting | 4 | 30 | | | Medical Research Institute of New Zealand, The Health Research Council of New Zealand (HRC) | Asthma | | | | |
| Not yet recruiting | 4 | 46 | | | Prof Philip Bardin | Severe asthma, Vocal cord Dysfunction | | | | |
ACTRN12621000614897p: Comparison of two tapering regimens in the management of glucocorticoid withdrawal - the PRED-STOP trial
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| Not yet recruiting | 4 | 120 | | | A/Prof W Inder - Investigator initiated, Metro South Study, Education and Research Trust Account | asthma; glucocorticoid-responsive dermatological conditions; rheumatoid arthritis; polymyalgia rheumatica; pituitary-adrenal axis suppression | | | | |
ACTRN12621000614897: Comparison of two tapering regimens in the management of glucocorticoid withdrawal - the PRED-STOP trial
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| Not yet recruiting | 4 | 120 | | | A/Prof W Inder - Investigator initiated, Metro South Study, Education and Research Trust Account | asthma, glucocorticoid-responsive dermatological conditions, rheumatoid arthritis, polymyalgia rheumatica, pituitary-adrenal axis suppression | | | | |
ACTRN12612000829819: In children presenting to the emergency department with a moderate acute asthma attack, does the addition of ipratropium bromide decrease hospital admission rate? |
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| Not yet recruiting | 4 | 128 | | | john hunter emergency, John Hunter Hospital Emergency Department | asthma | | | | |
| Not yet recruiting | 4 | 135 | | | Dr John D Brannan, GlaxoSmithKline | Asthma | | | | |
ACTRN12622000232730: Monitoring Intermittent vs Regular inhaled corticoSteroids in asthma: MIRSA study |
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| Not yet recruiting | 4 | 135 | | | Dr John D Brannan, GlaxoSmithKline | Asthma | | | | |
| Not yet recruiting | 4 | 300 | | | University of Newcastle, National Health and Medical Research Council - Medical Research Future Fund | Asthma | | | | |
| Recruiting | 4 | 94 | | | Mater Health Services Brisbane Respiratory Medicine Research Department, Asthma Foundation of Queensland | Asthma | | | | |
| Recruiting | 4 | 150 | | | Medical Research Institute of New Zealand, Capital & Coast District Health Board | Acute asthma | | | | |
ACTRN12605000465651: A 13 month, randomised, double-blind, parallel-group comparison of the efficacy of Seretide (fluticasone propionate/salmeterol combination Accuhaler) and Flixotide (fluticasone propionate Accuhaler) when down-titrating the inhaled corticosteroid dose in asthmatic adults who have previously received Seretide 500/50 ug twice daily for at least 4 weeks. |
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| Active, not recruiting | 4 | 70 | | | GlaxoSmithKline Australia Pty Ltd | Asthma | | | | |
ACTRN12609000551291: The effect of regular paracetamol on asthma symptoms in mild to moderate asthma |
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| Active, not recruiting | 4 | 132 | | | Medical Research Institute of New Zealand, Medical Research Institute of New Zealand, Wellington Medical Research Foundation Incorporated, Health Research Council of New Zealand | Asthma | | | | |
ACTRN12618000303246: Paracetamol or Ibuprofen in the Primary Prevention of Asthma in Tamariki (PIPPA Tamariki). |
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| Recruiting | 4 | 3922 | | | Auckland District Health Board, Health Research Council of New Zealand | Asthma, Bronchiolitis, Viral induced wheeze, Eczema, Atopy | | | | |
ChiCTR-TRC-13003343: The Optimized Nebulization Therapy for Moderate-to-Severe Acute Exacerbation of Asthma in Children |
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| Completed | 4 | 75 | | oxygen-driven (6L/min) nebulized inhalation of a mixed solution which contained 0.5% salbutamol (150 μg/kg, up to a maximum of 5 mg) and 0.025% ipratropium bromide (1 mL), plus 0.05% budesonide (2 mL) | State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical College; State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical College, Guangdong Health Department Foundation (Project ID# A2003284) | Asthma | | | | |
ChiCTR-OCC-13003316: Changes in lung function and biomarkers during recovery from acute asthma exacerbations in adults |
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| Completed | 4 | 90 | | inhaled corticosteroid ;no | The Affiliated Hospital of Guangdong Medical College; Level of the institution：, NO | bronchial asthma | | | | |
2005-005874-65: Non-invasive monitoring of airway inflammation in asthmatic patients during adaptation of inhaled steroid therapy |
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| Ongoing | 4 | 40 | Europe | Symbicort Turbohaler, Inhalation powder | University Hospital Antwerp | asthma | | | | |
2006-005097-52: A Single-Centre, Randomised, double-blind, two month Interventional Parallel group Study Assessing the in vivo synergy of salmeterol xinafoate/fluticasone propionate (50/250 μg twice daily) via a single Diskus inhaler (combination) versus salmeterol xinafoate (50 μg twice daily) and fluticasone propionate (250μg twice daily) via separate Diskus inhalers (concurrent treatment) on eosinophilic inflammation in the lungs of adult subjects > 18 years old who have moderate bronchial asthma. |
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| Ongoing | 4 | 20 | Europe | Inhalation powder, pre-dispensed, Seretide 250 Diskus 50/250 microgram/dose inhalation powder, pre-dispensed., Flixotide Diskus 250 micrograms, Inhalation powder, pre-dispensed, Serevent Diskus, 50 micrograms | Adelaide & Meath Hospital, Adelaide & Meath Hospital, incorporating the National Children's hospital | Eosinophilic inflammation in the lungs of adult subjects > 18 years old who have moderate bronchial asthma. | | | | |
ChiCTR-TNRC-09000437: The Role of High-Resolution Computerized Tomography in Evaluating the Degree of Airway Remodeling in the Moderate Asthmatic Patients Administrated with Formoterol-Budesonideare. |
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| Completed | 4 | 60 | | formoterol-budesonide ;Healthy subjects, no intervention | West China Hospital, Sichuan University, Chengdu, China; Level of the institution：, Self-finance | Asthma | | | | |
ChiCTR-TNRC-10000998: Impact of Smoking on Asthma and the Effect of Leukotriene Receptor Antagonist in asthma with smoking |
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| Completed | 4 | 37 | | Budesonide 200ug, inhalation, twice daily; salbutamol, inhalation, prn; Montelukast 10mg qn po. for 2 months ;Budesonide 200ug,inhalation, twice daily; salbutamol, inhalation, prn for 1month | Zhongshan Hospital, Fudan University; Level of the institution：, Zhongshan Hospital,Fudan University | asthma | | | | |
ChiCTR-OPC-15006105: Investigate the indoor allergen exposure and evaluate the efficacy of allergy immunotherapy on allergic rhinitis and/or asthma children |
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| Completed | 4 | 81 | | immunotherapy ;symptomatic drug | Nanjing Children's hospital; Nanjing Children's hospital, Research funds | House dust mite induced allergic asthma/rhinitis | | | | |
ChiCTR-TRC-09000464: Research on comprehensive thrapy with traditional Chinese medicine for acute attack of bronchial asthmas |
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| Completed | 4 | 396 | | Applying with Chinese drugs at the acupoint (Fei Yu, Ding Chuan, Shan Zhong, Tian Tu) bid 10 days; Granules of Chinese medicine formula as Group C; add Ventolin Aerosol if needed. ;Theophylline Sustainderelease bid 10 dyas; Flixotide Aerosol 125μg/inhale bid 10 dyas; add Ventolin Aerosol if needed. ;Hot wheezing: Qinlong Zhixiao Decoction Granules bid 10 days; cold wheezing: Suma Wenfei Pingxiao Decoction Granules bid 10 days; windy wheezing: Masu Zhixiao Decoction Granules bid 10 days; add Ventolin Aerosol if needed | Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine; Level of the institution：, Ministry of Science and Technology | Bronchial asthmas | | | | |
ChiCTR-TRC-10001072: Xiaoqinglong Granules for the treatment of mild and persistent asthma with: a randomized controlled, double-blind clinical study |
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| Completed | 4 | 180 | | Seretide + Xiaoqinglong granules ;Seretide + Placebo | China National Center for Biotechnology Development; Ministry of national science and technology, China, National Eleventh Five-Year Key Technology R&D Program | mild/persistent asthma | | | | |
ChiCTR-TRC-09000370: A randomized controlled trial of different therapy protocols for cough variant asthma |
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| Completed | 4 | 90 | | diprophylline 200mg + terbutanline 2.5 mg three times per day ;diprophylline 200mg three times per day + terbutanline 2.5 mg three times per day + budesonide 200 mg twice a day ;those unresponse to diprophylline and terbutanline inhale budesonide 200 mg twice a day | Tongji Hospital Affiliated to Tongji University; Level of the institution：, Self-financed | Cough variant asthma | | | | |
2011-000924-14: Development of a sputum biomarker panel to diagnose different types of asthma |
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| Ongoing | 4 | 40 | Europe | Inhalation powder, Qvar | KU Leuven LRD, KU Leuven LRD | asthma, airway disease characterized by chest tightness, wheezing, cough and breathless, Body processes [G] - Immune system processes [G12] | | | | |
2012-002106-48: An Investigative Study to characterize gene expression patterns in myeloid cells that are triggered during acute asthma exacerbations, and to identify associated genes/gene networks that are Omalizumab sensitive. |
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| Ongoing | 4 | 20 | Europe | Xolair Powder and Solvent for Injection | University College Dublin | Asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2012-001771-36: CLINICAL TRIAL: TREATMENT OF OXYGEN AT HIGH DOSES IN CHILDREN WITH ASTHMA CRISIS MODERATE / SEVERE IN THE EMERGENCY UNIT ENSAYO CLINICO: TRATAMIENTO DE OXIGENO A DOSIS ELEVADAS EN NIÑOS CON CRISIS ASMATICA MODERADA/ SEVERA EN EL SERVICIO DE URGENCIAS |
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| Ongoing | 4 | 120 | Europe | OXIGENO, OXIGENO, Gas and solvent for dispersion for injection/infusion, OXIGENO MEDICINAL LIQUIDO EN RECIPIENTE CRIOGENICO FIJO | FRANCISCO JAVIER BENITO FERNANDEZ, HOSPITAL UNIVERSITARIO CRUCES, DEPARTAMENTO DE SANIDAD GOBIERNO VASCO, MINISTERIO DE SANIDAD, SERVICIOS SOCIALES E IGUALDAD | Objectives: To evaluate the feasibility and explore the efficacy, safety and tolerability of the administration of oxygen at high flow during the stay of these children in the Pediatric Emergency Department (PED) to prevent hospitalization Objetivos: evaluar la factibilidad y explorar la eficacia, seguridad y tolerancia de la administración de oxigenoterapia en alto flujo (OAF) durante la estancia de estos niños en el Servicio de Urgencias de Pediatría (SUP) para prevenir su hospitalización, CLINICAL TRIAL OF STANDARD TREATMENT VS OXYGEN AT HIGH DOSES IN CHILDREN SUFFER FROM ACUTE ASTHMA IN PEDIATRICS EMERGENCY. ENSAYO CLINICO DE TRATAMIENTO HABITUAL FRENTE A OXIGENO A DOSIS ALTAS EN NIÑOS CON CRISIS ASMATICA EN EL SERVICIO DE URGENCIAS DE PEDIATRIA., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02] | | | | |
ChiCTR-ONRC-14004800: Pharmacokinetics study of trantinterol hydrochloride tablets in the elderly volunteers after a single dose administration |
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| Completed | 4 | 22 | | healthy elderly subjects ;healthy elderly subjects | The Third Xiangya Hospital of Central South University; Level of the institution：, Jiu Tai Pharmaceutical Co., Ltd | Asthma | | | | |
ChiCTR-PRC-09000529: Clinical study of Chinese herbs for reinforcing 'shen' and supplementing 'qi' in the prevention of bronchial asthma |
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| Completed | 4 | 360 | | Chinese drugs for reinforcing shen and supplementing qi placebo+Bushen Fangchuan Pian placebo ;Bushen Fangchuan Pian (5 tablets, tid, orally taken for 12 weeks) + Chinese drugs for reinforcing shen and supplementing qi placebo ;Chinese drugs for reinforcing shen and supplementing qi (125ml, bid, orally taken for 12 weeks) +Bushen Fangchuan Pian (placebo) | Huashan Hospital Fudan University; Jiangsu Province Hospital of TCM, West China Hospital of Sichuan University, et. al, Ministry of Science and Technology | Bronchial asthma | | | | |
ChiCTR-OCH-10001103: Clinical research of predicting acute exacerbations of asthma by peak expiratory flow (PEF) |
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| Completed | 4 | 800 | | Test peak expiratory flow (PEF) ;Test peak expiratory flow (PEF) | The First Hospital Affiliated to Dalian Medical University; Liaoning Provincial Health Department, Medical disciplinary project in Liaoning Province | asthma | | | | |
ChiCTR-TRC-14004770: Effects of Increasing the Dose for SMART Scheme Maintenance on Improving Moderate-Severe Asthma |
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| Completed | 4 | 80 | | budesonide versus formoterol(160/4.5ug) | First Affiliated Hospital of Guangzhou Medical University, Guangdong 510012，China; First Affiliated Hospital of Guangzhou Medical University, funded by the Guangzhou Medical University for the young investigator | Asthma | | | | |
| Completed | 4 | 60 | | Budisonide nasal spray and Budisonide/formoteral ;Placebo and Budisonide/formoteral | Guangzhou Institute of Respiratory Diseases; Guangzhou Institute of Respiratory Diseases, selffinance | asthma | | | | |
ChiCTR-TRC-09000486: Clinical study of Chinese herbs for reinforcing 'shen' and supplementing 'qi' in the prevention and cure of bronchial asthma |
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| Completed | 4 | 360 | | Budisonide+Bushen Fangchuan Pian(5 tablets,tid,orally taken for 12 weeks) ;Budisonide+chinese drugs for reinforcing shen and supplementing qi(125ml,bid,orally taken for 12 weeks) ;Budisonide+Chinese drugs for reinforcing shen and supplementing qi placebo+Bushen Fangchuan Pian placebo | Huashan Hospital Affiliated to Fudan University; Ministry of Science and Technology, Ministry of Science and Technology | Bronchial asthma | | | | |
ChiCTR-TRC-13003395: A randomized controlled clinical trial of using inhaling Budesonide powder in treatment of cough variant asthma |
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| Completed | 4 | 120 | | inhaled budesonide (400ug/day) for 3 months ;inhaled budesonide (400ug/day) for 6 months ;inhaled budesonide (400ug/day) for 12 months | Huashan hospital, Fudan University; Level of the institution：, Self support | cough variant asthma | | | | |
2014-002996-27: A study to determine the best use of salbutamol in children with acute severe asthma |
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| Ongoing | 4 | 100 | Europe | Salbutamol sulphate, Concentrate and solvent for suspension for injection, Ventolin injection | Great Ormond Street Hospital For Children NHS Foundation Trust | The mainstay of asthma treatment worldwide are β2-agonists and steroids. Current management of childhood acute asthma is based on British Thoracic Society guidelines, which recommend IVS as second line treatment. Whilst IVS can be highly effective in reversing bronchospasm, the overall evidence for this recommendation is week and predominantly comes from a single study. IVS has also been associated with side effects such as arrhythmias, lactic acidosis and diastolic hypotension., Every 18 minutes, a child is admitted to hospital with an acute asthma attack. Salbutamol is the main treatment and has saved countless lives. However, current dosages lead to frequent side effects, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2014-004799-50: Regulatory role of the immune system of Prevenar 13 vaccine in children with asthma and diabetes. Papel regulador del sistema inmune de la vacuna Prevenar 13 en niños con asma y diabetes . |
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| Ongoing | 4 | 150 | Europe | Prevenar 13, Suspension for injection, Prevenar 13 | Federico Martinon Torres, Genetic, Vaccines, Infectious Disease and Pediatrics Research Group | Allergic asthma and type 1 diabetes mellitus in pediatric subjects. Asma alérgica y diabetes mellitus tipo 1 en sujetos pediátricos., Asthma and diabetes in children Asma y diabetes en niños, Diseases [C] - Immune System Diseases [C20] | | | | |
2014-005611-16: Effect of Intravenous Administration of C1-inhibitor on Inflammation and Coagulation after Bronchial Instillation of House Dust Mite Allergen and Lipopolysaccharide in Allergic Asthma Patients |
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| Ongoing | 4 | 60 | Europe | Human C1-inhibitor, Powder and solvent for solution for infusion, Capsule, Film-coated tablet, Coated tablet, Cinryze, Vancocin, Ciprofloxacine Actavis, Metronidazol | Academic Medical Center, University of Amsterdam, Academic Medical Center, University of Amsterdam | Mild asthmatics with house dust mite allergy, Mild asthmatics with house dust mite allergy, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2014-003204-70: Pilot study on asthma control in patients with grass- pollen allergic rhinitis treated with 5 grass-pollen sublingual immunotherapy (Staloral®) vs placebo Estudio piloto sobre el control del asma en pacientes con rinitis alérgica a polen de gramíneas tratados con inmunoterapia sublingual de 5 gramíneas (Staloral®) vs placebo |
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| Ongoing | 4 | 74 | Europe | Sublingual spray, solution, Staloral Pollens maintenance 300 IR/ml sublingual solution | Dr. Javier Domínguez Ortega, STALLERGENES IBERICA S.A. | Respiratory Allergy: Asthma and allergic rhinitis due to grass pollen Alergia respiratoria: Asma y rinitis alérgicas por polen de gramíneas, Respiratory Allergy Alergia respiratoria, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
| Completed | 4 | 320 | | basical treatment plus ChuanKeZhi injection ;basical treatment plus ChuanKeZhi injection | Guangzhou Women and Children's Medical Center; Level of the institution：, Guangzhou ImVin Pharmaceutical Co.,Ltd. | Asthma | | | | |
ChiCTR-IPR-16008106: The Loki zupa in the treatment of patients with abnormal phlegmatic temperament bronchial asthma: a multicenter, randomised, double-blind, placebo controlled clinical trial |
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| Completed | 4 | 220 | | Seretide +Loki zupa ;Seretide +Placebo of Loki zupa | Huashan Hospital Fudan University; Huashan Hospital Fudan University, Shanghai municipal government | Bronchial asthma | | | | |
2007-004541-15: A Randomized Controlled Open-Label Phase IV Mono Center Study to Compare the Reponse Profiles of Montelukast versus Fluticason in Children with Preschool Asthma |
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| Ongoing | 4 | 100 | Europe | Singulair, Flutide, Singulair junior, Singulair mini 4mg Kautablette, Flutide mite 50 Dosier-Aerosol, Singulair junior 5mg Kautablette, Singulair mini 4mg Kautablette, Flutide mite 50 Dosier-Aerosol, Singulair junior 5mg Kautablette | Johann Wolfgang Goethe-Universität Frankfurt am Main | bronchial asthma is a very common medical problem in 3-7 year old children, often requiring hospitalization and demanding treatment on demand or permanently. Our trial is to compare to established treatment regimens with regard to their clinical efficacy | | | | |
2005-001466-14: A Proof of Concept Study to Investigate the use of Simvastatin as a Putative Anti-inflammatory Agent in Asthma |
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| Ongoing | 4 | 20 | Europe | Salmeterol xinafoate, Simvastatin, Serevent inhaler, Zocor, Serevent inhaler, Zocor | University of Dundee | Asthma | | | | |
2005-001997-29: A Proof of Concept Study into the Effects on Inhlaed Extra-Fine and Standard Formulations of Beclomethasone Dipropionate and Oral Montelukast on Surrogate Markers of Small and Large Airway Inflammation in Asthma |
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| Ongoing | 4 | 30 | Europe | Beclazone, QVAR, Singulair, Beclazone, QVAR, Singulair | University of Dundee | Asthma | | | | |
2004-004614-16: Alternaria alternata inmunotherapy effects on AMP and methacholine bronchial answer and on inflammation markers in exhaled air (nitric oxide) and in condensated air (pH and hydrogen peroxide) in asthmatic patients and in patients with allergic rhinitis sensitized to Alternaria alternata. |
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| Ongoing | 4 | 42 | Europe | Alternaria alternata major allergen, Alternaria alternata major allergen, Alternaria alternata major allergen | DIATER LABORATORIES S.A. | Asthma and allergic rhinitis | | | | |
2005-003008-12: Prospective trial to evaluate the safety of one cluster regimen in patients with allergic rhinitis/ rhinoconjunctivitis and/or mild or moderate allergic asthma to grass polen, tree pollen or mites.b Estudio prospectivo para evaluar la seguridad de una pauta agrupada (CLUSTER) con inmunoterapia alergénica en rinitis /rinoconjuntivitis con o sin asma alérgico leve o moderado al polen de gramíneas, polen de olivo o ácaros |
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| Ongoing | 4 | 120 | Europe | ALUSTAL, ALUSTAL, ALUSTAL | STALLERGENES | Allergic rhinitis / rhinoconjunctivitis and/or mild or moderate allergic asthma to grass pollen, tree pollen or mites. | | | | |
| Ongoing | 4 | 220 | Europe | none, none, Slow sodium, Slow sodium | University of Nottingham, Hospital do Servidor Publico Municipal | upper airway obstruction, croup, endotracheal intubation, respiratory failure, mechanical ventilation, extubation failure | | | | |
2005-004475-37: Comparative study of the bioactivity of the HFA Fluticasone Dipropionate via current delivery devices |
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| Ongoing | 4 | 20 | Europe | Flixotide 250 microgram evohaler, Flixotide 250 microgram Evohaler, Flixotide 250 microgram Evohaler | University of Dundee ( Research & Innovation Services) | Bronchial Asthma | | | | |
2005-005622-31: A Proof Of Concept Study To Investigate The Potential Role Of Acetylsalicyclic Acid (Aspirin) As An Anti-Inflammatory Agent For The Treatment Of Asthma |
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| Ongoing | 4 | 20 | Europe | Aspirin, Ranitidine Hydrochloride, Nu-Seals 75, Zantac Tablets 300mg, Nu-Seals 75, Zantac Tablets 300mg | University of Dundee | Asthma | | | | |
2005-004115-29: Investigation to identify predictors of response to a treatment with montelukast |
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| Ongoing | 4 | 30 | Europe | singulair junior 5 mg, SINGULAIR junior° 5 mg, SINGULAIR junior° 5 mg | Research Institute for the prevention of allergy and airway diseases in childhood | asthma bronchiale in childhood | | | | |
2006-000334-12: A RANDOMIZED, PLACEBO CONTROLLED, DOUBLE-BLIND, CROSS-OVER, MONOCENTER STUDY TO EVALUATE THE EFFECT OF A 7-DAY MONTELUKAST TREATMENT ON AIRWAY INFLAMMATION AND FUNCTION BY MEANS OF BRONCHOPROVOCATION WITH ADENOSINE-5’-MONOPHOSPHATE IN PATIENTS WITH MILD OR MODERATE ALLERGIC ASTHMA |
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| Ongoing | 4 | 18 | Europe | Montelukast, Montelukast capsule, | Almirall Prodesfarma | Mild to moderate asthma according to GINA (Global initiative for Asthma, 2004) guidelines. | | | | |
2005-005531-99: A PROOF OF CONCEPT STUDY TO ASSESS THE STEROID SPARING EFFECT OF COMBINED NASAL AND INHALED CORTICOSTEROID IN PATIENTS WITH ASTHMA AND PERSISTENT RHINITIS |
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| Ongoing | 4 | 30 | Europe | Flixotide 50 micrograms Evohaler, Flixonase Aqueous Nasal Spray, Flixotide 50 micrograms Evohaler, Flixonase Aqueous Nasal Spray | University of Dundee(Research & Innovation Services) | Bronchial Asthma | | | | |
2006-001104-36: COMPARATIVE LUNG BIOAVAILABILITY OF HFA-SERETIDE VIA SPACER DEVICES IN HEALTHY VOLUNTEERS |
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| Ongoing | 4 | 20 | Europe | Seretide 250 Evohaler, Seretide 250 Evohaler, Seretide 250 Evohaler | University of Dundee (Research & Innovation Services) | Bronchial Asthma | | | | |
2006-001559-37: A study to observe the effects of one month’s supplementation with forceval junior on asthma control in children aged 7-12 years with asthma. |
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| Ongoing | 4 | 30 | Europe | Forceval Junior Capsules, Forceval Junior Capsules, Forceval Junior Capsules | University of Aberdeen | Asthma | | | | |
2006-002450-30: An Open label Study to Compare Systemic Side Effects of High Dose Fluticasone/Salmeterol with that of High Dose Ciclesonide /Salmeterol in Symptomatic Asthmatics |
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| Ongoing | 4 | 20 | Europe | Alvesco 160 inhaler, Flixotide Accuhaler, Alvesco 160 inhaler, Flixotide Accuhaler | Hull and East Yorkshire Hospitals Trust | Chronic asthma | | | | |
2006-003417-41: The effect of nebulised MgSO4 on lung function in stable severe asthma patients with persistent airflow limitation |
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| Ongoing | 4 | 12 | Europe | Magnesium sulfate 6,4 % solution for nebulisation, | Medical Centre Leeuwarden | Patients with severe asthma and persistent airflow limitation | | | | |
| Ongoing | 4 | 800 | Europe | Placebo, AD-Vitamin Olja, AD-vitamin Olja, AD-vitamin Olja | Ove Bäck, Dept Dermatology, University Hospital, Lund, Sweden | Cumulative incidence of atopic allergy specified as atopic dermatitis, allergic asthma, and allergic rhinitis.Since IMP is a food supplement to protect from rickets we are looking at clinical symptoms of vitamin D deficiency as well and measure serum levels of calcidiol. | | | | |
2007-003543-67: Assessment of bronchial hyperresponsiveness in children - inhalation of Mannitol compared to eucapnic voluntary hyperventilation and methacholine provocation |
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| Ongoing | 4 | 20 | Europe | Methacholine inhalation, Aridol, Aridol | Karolinska Universitetssjukhuset | Three different methods to assess airway hyperresponsiveness in children with allergic asthma will be compared. | | | | |
| Ongoing | 4 | 450 | Europe | Flixotide Accuhaler, Seretide Accuhaler, Singulair, Flixotide Accuhaler, Seretide Accuhaler, Singulair | Keele University, University Hospital of North Staffordshire NHS Trust | Chronic asthma (paediatric population) | | | | |
2007-005550-23: Ipratropio bromuro-albuterol association vs salbutamolo in asthma and gastroesophageal reflux |
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| Ongoing | 4 | 34 | Europe | BREVA, BRONCOVALEAS, BREVA, BRONCOVALEAS | ISTITUTO GIANNINA GASLINI | asthma | | | | |
2008-002844-40: A DOUBLE BLIND, SINGLE DOSE, RANDOMIZED, 4-PERIOD CROSS-OVER, PLACEBO-CONTROLLED CLINICAL STUDY OF FIXED COMBINATION BECLOMETHASONE DIPROPIONATE PLUS FORMOTEROL FUMARATE (CHF 1535) VERSUS SINGLE AGENTS FORMOTEROL FUMARATE AND BECLOMETHASONE DIPROPIONATE VIA pMDI WITH HFA-134A PROPELLANT, WHEN GIVEN AFTER INHALED ALLERGEN CHALLENGE IN ASTHMATIC PATIENTS |
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| Ongoing | 4 | 20 | Europe | CHF 718 HFA, CHF 718 HFA, Atimos, Foster, Atimos, Foster | Leiden University Medical Center | astma | | | | |
2009-012108-15: Korrelation von freiem IgE mit klinischen Parametern bei Asthma-Patienten unter Therapie mit Omalizumab, einem monoklonalen Antikörper gegen körpereigenes IgE |
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| Ongoing | 4 | 20 | Europe | Xolair 150 mg powder and solvent for solution for injection, Xolair 150 mg powder and solvent for solution for injection | Mainz University Hospital | Add-on therapy to improve asthma control in patients 18-75 years of age with severe persistent allergic asthma who have a positive skin test or in vitro reactivity to a perennial aeroallergen and who have reduced lung function (FEV1 <80%) as well as frequent daytime symptoms or night-time awakenings and who have had multiple severe asthma exacerbations despite daily high-dose inhaled corticosteroids, plus a long-acting inhaled beta2-agonist. | | | | |
| Ongoing | 4 | 100 | Europe | Actos, Actos | Nottingham University | Asthma | | | | |
2008-002244-42: Test if adding Vitamin D, a safe standard vitamin supplement to steroid tablets, will improve the clinical response to steroids in patients who are considered to be steroid resistant |
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| Ongoing | 4 | 40 | Europe | Rocaltrol Capsules, Prednisolone, Rocaltrol Capsules 0.25mcg, Prednisolone, Rocaltrol Capsules 0.25mcg, Prednisolone | King\'s College London, Guy\'s and St Thomas\' NHS Foundation Trust, Asthma UK | Asthma | | | | |
2009-012053-37: Dose response of FENO to inhaled steroids in mild-to-moderate asthma |
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| Ongoing | 4 | 25 | Europe | Flixotide 50 micrograms Evohaler, Flixotide 250 micrograms Evohaler, PL 10949/0324, PL 10949/0266, Flixotide 50 micrograms Evohaler, Flixotide 250 micrograms Evohaler, Flixotide 50 micrograms Evohaler, Flixotide 250 micrograms Evohaler | University of Dundee | Asthma | | | | |
2009-011452-21: Study of the effectiveness of Voriconazole in the treatment of Aspergillus fumigatus associated asthma |
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| Ongoing | 4 | 85 | Europe | Voriconazole, Vfend, Vfend | University Hospitals of Leicester NHS trust | Asthma with sensitization to aspergillus and isolation in sputum. | | | | |
2010-018937-23: The predictive value of the acute effect of beclomethasone on a mannitol challenge test for the outcome of lomgterm treatment with beclomethasone |
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| Ongoing | 4 | 19 | Europe | beclomethasone, Qvar 100 Aerosol, Qvar 100 Aerosol | Medisch Spectrum Twente | Exercise induced asthma / bronchoconstrictionAsthma | | | | |
2011-003652-39: Exercise induced bronchoconstriction in children – a single dose of montelukast as alternative to regular daily doses. Anstrengelsesudløst astma hos børn – enkeltdosering af montelukast som alternativ til fast daglig dosering. |
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| Ongoing | 4 | 32 | Europe | Singulair, Singulair | Karen Schow Jensen, Forskningspuljen Hillerød Hospital, Kaptajnløjtnant Harald Jensens og hustrus Fond, Aase og Ejnar Danielsens Fond, Direktør Jacob Madsen & Hustru Olga Madsens Fond, Carl og Ellen Hertz’ legat til Dansk Læge- og Naturvidenskab, Dagmar Marshalls Fond | Exercise induced asthma | | | | |
2013-002722-23: The protective effect of one dose asthma medication with different body postures against exercise asthma Het beschermende effect van één puff asthma medicijn in verschillende lichaamshoudingen op inspanningsastma. |
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| Ongoing | 4 | 38 | Europe | Beclomethason-diproprionaat (Qvar) autohaler dosisaerosol, Beclomethason-diproprionaat (Qvar) autohaler dosisaerosol | Medisch Spectrum Twente, Stichtin Pedriatrisch Onderzoek Enschede | Exercise Induced Bronchoconstriction Inspannings-geinduceerde bronchoconstrictie | | | | |
2013-002769-20: The protective effect of one dose asthma medication against exercise asthma. Het beschermende effect van één puff astma medicijn tegen inspanningsastma. |
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| Ongoing | 4 | 15 | Europe | Airomir, Airomir | Medisch Spectrum Twente, Stichting Pediatrisch Onderzoek Enschede | Exercise induced bronchoconstriction Inspannings geinduceerde bronchoconstrictie | | | | |
2013-003941-41: Change of lung function after inhaling rescue asthma medication in different amounts in straight up and forward leaning body posture in asthmatic children |
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| Ongoing | 4 | 15 | Europe | Airomir, Airomir | Medisch Spectrum Twente, Stichting Pediatrisch Onderzoek Enschede | Asthma | | | | |
2014-001029-34: The inhaled combination of budesonide-formoterol consists a basic asthma treatment.A helpful specific index for the prognosis of future exacerbation risk and deterioration of lung function,is the Exhaled Nitric Oxide.The objective of the current study is the evaluation of Pulmoton- Elpenhaler in Exhaled Nitric Oxide of patients with bronchial asthma. Ο εισπνεόμενος συνδυασμός βουδεσονίδης-φορμοτερόλης αποτελεί τη βασική θεραπεία για το άσθμα. Ένας ειδικός δείκτης που βοηθά στην πρόγνωση μελλοντικού κινδύνου παρόξυνσης και μείωσης της λειτουργίας των πνευμόνων, είναι το εκπνεόμενο μονοξείδιο του αζώτου.Η παρούσα μελέτη έχει ως κύριο σκοπό την αξιολόγηση της επίδρασης του εισπνεόμενου συνδυασμού βουδεσονίδης-φορμοτερόλης (Pulmoton® Elpenhaler®) στο εκπνεόμενο μονοξείδιο του αζώτου ασθενών με βρογχικό άσθμα. |
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| Ongoing | 4 | 108 | Europe | Pulmoton/Elpenhaler, Symbicort Turbuhaler, Pulmoton/Elpenhaler (200/6)mcg, Symbicort Turbuhaler, Pulmoton/Elpenhaler (200/6)mcg, Symbicort Turbuhaler | ELPEN Pharmaceutical Co. Inc, ELPEN Pharmaceutical Co. Inc. | Bronchial Asthma Bρογχικό Άσθμα | | | | |
2012-001591-11: Treatment of hay fever and the relation with asthma in children in de general practice office Behandeling van hooikoorts en de relatie met astma bij kinderen in de huisartspraktijk |
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| Ongoing | 4 | 411 | Europe | Levocetirizine, Fluticasone, RVG 26770, RVG 14424, Xyzal, Flixonase, Xyzal, Flixonase | Erasmus MC, Astma Fonds | Allergic Rhinitis Asthma Allergische rinitis Astma | | | | |
2013-003145-42: COMPARISON OF TWO DIFFERENT CORTICOIDS TREATMENTS WITH POWER AND ADMINISTRATION ON THE TREATMENT OF IN CHILDREN WITH ACUTE ASTHMA IN PEDIATRIC EMERGENCY COMPARACION DE DOS TRATAMIENTOS CORTICOIDEOS CON DIFERENTES POTENCIAS Y PAUTAS EN EL TRATAMIENTO DE LA CRISIS DE ASMA EN NIÑOS EN LA URGENCIA PEDIATRICA |
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| Ongoing | 4 | 1000 | Europe | DEXAMETHASONE, PREDNISOLONA, PREDNISONA, DEXAMETHASONE, PREDNISOLONA, PREDNINSONA, Se utilizará el nombre comercial de este principio activo que este disponible en el Hospital, Se utilizará el nombre comercial de este principio activo que este disponible en el Hospital | FRANCISCO JAVIER BENITO FERNANDEZ, HOSPITAL UNIVERSITARIO CRUCES (OSAKIDETZA) | ASTHMA ASMATICA | | | | |
2015-004455-52: An open 4-week study to evaluate the efficacy and safety of Serroflo ® comparing with Viani ® in patients with stable persistent asthma Eine offene 4-Wöchige klinische Studie zur Bestimmung der Sicherheit und Wirksamkeit von Serroflo® im Vergleich zu Viani® bei Patienten mit stabilem anhaltendem Asthma |
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| Ongoing | 4 | 220 | Europe | Pressurised inhalation, suspension, SERROFLO 25 Mikrogramm / 125 Mikrogramm / Dosis Druckgasinhalation, Suspension, Viani Dosier-Aerosol 25 μ g/125 μ g Druckgasinhalation, Suspension | Cipla Europe NV, Cipla Europe NV | Asthma, Asthma Asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2016-000357-12: The influence of small airway inflammation on symptoms in patients with asthma |
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| Ongoing | 4 | 100 | Europe | Triamcinolone acetonide, 05341, Injection, Kenacort-A 40 | Stichting Longgeneeskunde Fryslan, GSK (grant), MCL academie (grant) | Asthma, Asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
ChiCTR-TRC-13003909: Optimized programme of sequential treatment of Traditional Chineses Medicine for brochial asthma |
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| Completed | 4 | 144 | | maqinkechuanheji; bufeikeli ;seretide | The second affiliated hospital of Tianjin Medical University; The second affiliated hospital of Tianjin Medical University, Tianjin science and technology plan projects (13ZCZDSY02100) | Bronchial asthma | | | | |
ChiCTR-TRC-14004375: Comparison of daily mometasone furoate nasal spray alone versus a combination with montelukast for treatment of chronic rhinosinusitis with asthma after functional endoscopic sinus surgery: a 9-month randomized, open-label, controlled study |
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| Recruiting | 4 | 60 | | Montelukast (10mg, once daily) for 6 months ;mometasone furoate nasal spray (200ug, once daily) for 6 months | The First Affiliated Hospital, Sun Yat-sen University; Level of the institution：, Industry Foundation of the Ministry of Health, China (201202005), | chronic rhinisinusitis with asthma | | | | |
2016-002276-27: The predictive value of the acute effect of beclomethasone-dipropionate on a mannitol challenge test for the outcome of longterm treatment with beclomethasone-dipropionate in childhood asthma |
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| Ongoing | 4 | 25 | Europe | Beclomethasone-dipropionate, R03AK08, Inhalation vapour, solution, Qvar 100 aerosol (beclomethasone-dipropionate) | Medisch Spectrum Twente, Medisch Spectrum Twente | exercise induced bronchoconstriction asthma, exercise induced bronchoconstriction asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2016-000164-42: investigating the use of allopurinol as treatment for allergic asthma |
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| Ongoing | 4 | 18 | Europe | Allopurinol, Capsule, Allopurinol | Tayside Medical Sciences Centre on behalf of University of Dundee | Asthma, Asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
ChiCTR-IPR-15007118: A nasally applied cellulose powder in the children andadolescent with combined perennial allergic rhinitis andasthma. A placebo-controlled double-blind group comparative study |
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| Recruiting | 4 | 120 | | Budesonide Nasal Spray 64ug bid andBudesonide andFormoterol Fumarate Powder for Inhalation 80ug/4.5ug/suck bid ;Nasaleze tid; Budesonide andFormoterol Fumarate Powder for Inhalation 80ug/4.5ug/suck bid ;Lactose powder tid; Budesonide andFormoterol Fumarate Powder for Inhalation 80ug/4.5ug/suck bid | State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated hospital of Guangzhou Medical University; First Affiliated hospital of Guangzhou Medical University, Shanghai Advanced Clinical Laboratory Science Co.,Ltd | Combined Allergic Rhinitis andAsthma Syndrome | | | | |
| Ongoing | 4 | 24 | Europe | Singulair, Coated tablet, Singulair | Department of Neurology, Christian Doppler Medical Center, Paracelsus Medical University Salzburg, Paracelsus Medical University Salzburg | Montelukast is indicated for prophylaxis and chronic treatment of asthma and for the relief of symptoms of seasonal allergic rhinitis.We investigate side effects of Montelukast, specifically potential effects on brain activity., Montelukast is used for treatment of asthma and allergic rhinitis. We examine the effect of Montelukast on brain activity., Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2015-003551-22: Study to look at the usefulness of an extra dose of salbutamol (medicine that widens the airways in the lungs) through the bloodstream, in children who are admitted to an intensive care for a very severe asthma-attack. Een studie om te kijken of het nuttig is om een extra dosis salbutamol te geven (medicijn dat de luchtwegen wijder maakt in de longen) via het bloed, bij kinderen die op een intensive care liggen voor een heel ernstige astma-aanval. |
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| Ongoing | 4 | 52 | Europe | Ventolin Infuus, oplossing voor injectie 0,5 mg/ml, Solution for injection, Ventolin Infuus, oplossing voor injectie 0,5 mg/ml | Erasmus MC - Sophia Children's Hospital, Sophia BV, Stichting AMMODO, Stichting Astma Bestrijding | Severe acute (viral) wheeze and severe acute asthma Ernstige acute (virale) wheeze en status asthmaticus, Life-threatening attacks of (viral) wheeze and life-threatening asthma attacks Levensbedreigende aanvallen van hijgen ("wheeze") door een luchtwegvirus, en levensbedreigende astma-aanvallen, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
| Ongoing | 4 | 900 | Europe | Fluticasone Furoate, Inhalation powder | GlaxoSmithKline Research & Development Limited, GlaxoSmithKline Research & Development Limited | Paediatric Subjects with Asthma, Paediatric Subjects with Asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2015-001736-38: The utility of feNO in the differential diagnosis of chronic cough |
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| Not yet recruiting | 4 | 60 | Europe | Montelukast, Prednisolone, Film-coated tablet, Tablet, Montelukast, Prednisolone | Hull and East Yorkshire Hospitals NHS trust, Aerocrine Limited | Chronic cough is a common and poorly diagnosed condition. Younger patients tend to receive a diagnosis of asthma, whereas older patients are increasingly identified has having gastroesophageal reflux disease. Those patients presenting with upper airway symptoms are frequently labelled as having rhinitis. A considerable proportion of patients elude a diagnosis, either through testing or by the use of therapeutic trials and are then labelled as idiopathic cough., Chronic cough is a common and poorly diagnosed condition. There are different causes of chronic cough the most common causes are asthma, postnasal drip and gastro-oesophageal reflux., Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
ChiCTR-OPC-16010009: The Real World Study of the Clnical Efficacy of Huaier Granule for Asthma Therapy |
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| Recruiting | 4 | 2000 | | inhale corticosteroids ;Huaier Granule | Capital Institute of Pediatrics; Capital Institute of Pediatrics, Qidong Gaitianli Pharmacy Ltd | Asthma | | | | |
ChiCTR-IIR-17012223: A Randomized, Open-labeled, Parallel Controlled Study on the Efficacy and Safety of Combined Medication with Procaterol Hydrochloride and Montelukast in Treatment of Cough variant Asthma in Children. |
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| Completed | 4 | 490 | | Procaterol Hydrochloride and Montelukast ;Montelukast | Beijing Children’s Hospital, Capital Medical University; Beijing Children's Hospital, Capital Medical University, Zhejiang Otsuka Pharmaceutical Co., Ltd | Cough variant Asthma | | | | |
2017-002244-33: Periostin-guided withdrawal of inhaled corticosteroids in patients withnon-eosinophilic asthma Periostin-guided withdrawal of inhaled corticosteroids in patients withnon-eosinophilic asthma |
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| Ongoing | 4 | 110 | Europe | budesonid, fluticasonpropionat, mometasonfuroat, fluticasonfuroat, ciclesonid, budesonid, R03BA05, R03BA07, R03AK10, R03BA08, Budesonid, fluticasonpropionat, mometasonfuroat, fluticasonfuroat, beclometasondipropionat, ciclesonid | Hvidovre Hospital, Hvidovre Hospital | Asthma Astma, Asthma Astma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2017-000735-14: A study comparing whether the new drug comprising fluticasone propionate and salmeterol doses of 125μg and 25μg HFA MDI inhaler (spray pressure) applied two puffs twice daily is not less effective than the dose of 500μg / 50μg applied one puff twice daily as powder inhaler (DPI) in patients with asthma Badanie porównujące czy nowy lek zawierający propionian flutikazonu I salmeterol w dawkach 125µg i 25µg w inhalatorze MDI HFA (aerozol ciśnieniowy) dwa wziewy dwa razy dziennie jest nie mniej skuteczny niż lek referencyjny w dawce 500µg/50µg jeden wziew dwa razy dziennie w inhalatorze proszkowym (DPI) u pacjentów z astmą oskrzelową |
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| Ongoing | 4 | 220 | Europe | Inhalation solution, Inhalation powder, COMBOTEROL fluticasone propionate/salmeterol (125μg / 25μg) in MDI HFA inhaler, Seretide Disc 500 fluticasone propionate/salmeterol (500μg / 50μg) in DPI device | Lek-Am Sp. z o.o., Lek-Am Sp. z o.o. | Asthma is a common, chronic respiratory disease affecting 1–18% of the population in different countries. Asthma is characterized by variable symptoms of wheeze, shortness of breath, chest tightness and/or cough, and by variable expiratory airflow limitation. Both symptoms and airflow limitation characteristically vary over time and in intensity. These variations are often triggered by factors such as exercise, allergen or irritant exposure, change in weather, or viral respiratory infections. Astma to heterogenna choroba, zwykle związana z przewlekłym zapaleniem dróg oddechowych, zdefiniowana przez zespół objawów ze strony układu oddechowego jak świsty, duszności, ucisk w klatce piersiowej i kaszel, zmieniających się w czasie i o różnym nasileniu, którym towarzyszy zmienna obturacja dróg oddechowych, Asthma is a common condition that affects the airways. The typical symptoms are wheeze, cough, chest tightness, and shortness of breath. Symptoms can range from mild to severe. Astma jest przedwlekłą chorobą dróg oddechowych. Typowe objawy to świszczący oddech, kaszel, ucisk w klatce piersiowej i duszność. Objawy mogą się wahać od łagodnych do bardzo ciężkich.., Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2018-000578-31: Impact of benralizumab treatment on asthma Einfluss einer Benralizumab-Behandlung auf Asthma |
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| Not yet recruiting | 4 | 20 | Europe | Fasenra, Fasenra | University Medicine Rostock, AstraZeneca | Eosinophilic Asthma Eosinophilic asthma, Asthma Asthma, Body processes [G] - Immune system processes [G12] | | | | |
2017-003958-16: Effect of Reslizumab on small airways in asthma. RESSAPEA Effect van Reslizumab op de kleine luchtwegen |
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| Ongoing | 4 | 33 | Europe | Solution for infusion, Cinqaero | Academic Medical Center, University of Amsterdam, Academic Medical Center | 1. Patients with severe eosinophilic asthma Ernstig eosinofiel astma patiënten, Patients with severe eosinophilic asthma Ernstig eosinofiel astma patiënten, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2018-002591-40: Evaluation of bronchial remodeling during mepolizumab treatment in severe eosinophilic asthma Evaluation du remodelage bronchique lors d’un traitement par mépolizumab dans l’asthme sévère éosinophile |
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| Not yet recruiting | 4 | 40 | Europe | Powder for solution for injection, Nucala | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS, LABORATOIRE GLAXOSMITHKLINE | severe oesinophilic asthma asthme sévère éosinophile, severe oesinophilic asthma asthme sévère éosinophile, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2018-003467-64: A 24-week Study aiming to characterise changes in airway inflammation, symptoms, lung function, and reliever use in asthma patients using Salbutamol or AntiInflammatory Reliever (SYMBICORT®) as rescue medication in addition to SYMBICORT as daily asthma controller. |
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| Not yet recruiting | 4 | 80 | Europe | Symbicort® Turbohaler® 100 micrograms/6 micrograms/inhalation, Symbicort® Turbohaler® 200 micrograms/6 micrograms/inhalation, Inhalation powder, Symbicort® Turbohaler® | Astra Zeneca AB, Astra Zeneca AB | Asthma, Asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
| Not yet recruiting | 4 | 16 | Europe | Striverdi Respimat, Spiriva Respimat, Inhalation solution, Striverdi Respimat, Spiriva Respimat | Tayside Medical Sciences Centre on behalf of University of Dundee & NHS Tayside | Asthma, Asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
| Not yet recruiting | 4 | 60 | Europe | Solution for injection, Fasenra (benralizumab) | University Hospital of Montpellier, AstraZeneca | The study population corresponds to severe eosinophilic asthma patients La maladie sur laquelle porte l'étude est l'asthme sévère avec éosinophilie, The study population corresponds to severe eosinophilic asthma patients, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
| Not yet recruiting | 4 | 150 | Europe | Fasenra, Not applicable, Solution for injection in pre-filled syringe, Solution for injection in pre-filled pen, Fasenra | NHS Greater Glasgow and Clyde, AstraZeneca | Severe Eosinophilic Asthma, Severe asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2016-002014-52: DUAL HOMING MECHANISMS OF EOSINOPHILS TO THE SPUTUM; ONLY ONE OF WHICH IS SENSITIVE FOR MEPOLIZUMAB; The FOOTSTEP study HET EFFECT VAN EEN NIEUW GENEESMIDDEL, NUCALA®, OP HET AFWEERSYSTEEM VAN MENSEN MET ASTMA: DE VOETSTAP STUDIE |
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| Not yet recruiting | 4 | 20 | Europe | Nucala, SB-240563, Nucala | University Medical Center Utrecht, GlaxoSmithKline | severe eosinophilic asthma, Treatment of patients with severe asthma that do not sufficiently respond to current treatment, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
ChiCTR-OIH-17012492: Safety of semi depot house dust mite allergen extract during initial treatment for children and adolescents with allergic rhinitis and/or allergic asthma |
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| Recruiting | 4 | 250 | | SCIT | Beijing Children's Hospital Capital Medical University; MerckSerono China, Merck Serono Co. Ltd. | Children and adolescents with allergic rhinitis and/or allergic asthma | | | | |
2019-003036-23: A study to explore why certain types of inhaled medications cause an increased risk of worse outcomes among asthma patients |
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| Not yet recruiting | 4 | 24 | Europe | Serevent 50 micrograms Accuhaler, Seretide 50/250 micrograms Accuhaler, Atrovent, Inhalation powder, Inhalation solution, Serevent 50 micrograms Accuhaler, Seretide 50/250 micrograms Accuhaler, Atrovent | Imperial College London, European Research Council | Asthma, Asthma (a lung disease in which the tubes in the lungs can become narrowed making it more difficult to breathe comfortably), Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2019-003768-31: Effects of azithromycin treatment on immunesystem in patients with asthma and COPD Effekten af azithromycin behandling på immunsystemet hos patienter med astma og KOL |
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| Ongoing | 4 | 100 | Europe | Azithromycin, J01FA10, Film-coated tablet, Azithromycin | Lungemedicinsk Forskningsenhed, Novo Nordisk Fonden | COPD and asthma, Chronic obstructive pulmonary disease and asthma, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
2019-003351-11: Study to the effects of using "triple therapy" on the health status of COPD patients with characteristics of asthma Een onderzoek naar het effect van het gebruik van “triple therapie” op de gezondheids-status van COPD-patiënten met kenmerken van asthma |
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| Not yet recruiting | 4 | 316 | Europe | Trimbow, Pressurised inhalation, Inhalation powder, Trimbow, Anoro or Duaklir Genuair Inhalationpowder or Ultibro Breezhaler or Spiolto Respimat | GPRI, General Practitioners Research Institute (GPRI) | Chronic Obstructive Pulmonary Disease (COPD) patients COPD patiënten, COPD COPD, Diseases [C] - Respiratory Tract Diseases [C08] | | | | |
ChiCTR-IIR-17011947: Clinical Research on Thymosin α1 Adjuvant Therapy to Improve Asthma Control Rate and Reduce the Risk of Acute Asthma |
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| Recruiting | 4 | 100 | | Basic treatment, and 6mg thymosin α1 subcutaneous injection 2 times a week and the course of treatment is 3 months (12 weeks) ;Basic treatment | Changzheng Hospital; Changzheng Hospital, Research-based physician development program of Changzheng Hospital | bronchial asthma | | | | |
