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10 Companies |
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17 Products |
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17 Products |
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0 Mechanisms of Action |
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1 Trial |
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21 News |
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- | Trial completion: Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor (clinicaltrials.gov) - Sep 7, 2018
P3, N=24, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed
- | NN1213 / Novo Nordisk
Trial completion, Surgery: Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors (clinicaltrials.gov) - Feb 20, 2018
P2, N=104, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Enrollment change, Trial termination: Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors (clinicaltrials.gov) - Apr 7, 2017
P1, N=2, Terminated, Sponsor: OHSU Knight Cancer Institute
Active, not recruiting --> Completed N=30 --> 2 | Suspended --> Terminated; OHSU IRB closed study to further enrollment 2/17/2006
- | emvododstat (PTC299) / PTC Therap
Trial completion, Trial primary completion date: PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors (clinicaltrials.gov) - May 4, 2015
P1, N=28, Completed, Sponsor: Pediatric Brain Tumor Consortium
N=30 --> 2 | Suspended --> Terminated; OHSU IRB closed study to further enrollment 2/17/2006 Suspended --> Completed | Trial primary completion date: May 2012 --> Jan 2015
- | Trial completion: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors (clinicaltrials.gov) - Apr 13, 2014
P1, N=94, Completed, Sponsor: Children's Oncology Group
Suspended --> Completed | Trial primary completion date: May 2012 --> Jan 2015 Recruiting --> Completed
- | cisplatin / Generic mfg., etoposide IV / Generic mfg.
Trial completion: Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors (clinicaltrials.gov) - Feb 19, 2014
P2, N=0, Completed, Sponsor: Mayo Clinic
Recruiting --> Completed Active, not recruiting --> Completed
- Rytelo (imetelstat) / Geron
Enrollment change: Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma (clinicaltrials.gov) - Jan 28, 2014
P1, N=34, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed N=45 --> 34
- | Rytelo (imetelstat) / Geron
Trial completion: Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma (clinicaltrials.gov) - Jan 28, 2014
P1, N=34, Completed, Sponsor: Children's Oncology Group
N=45 --> 34 Active, not recruiting --> Completed
- sunitinib / Generic mfg.
Enrollment change: Sunitinib in Treating Young Patients With Refractory Solid Tumors (clinicaltrials.gov) - Jan 26, 2014
P1, N=35, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed N=60 --> 35
- ||| Enrollment closed, Surgery: Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors (clinicaltrials.gov) - Jan 14, 2014
P2, N=104, Active, not recruiting, Sponsor: Children's Oncology Group
N=60 --> 35 Completed --> Active, not recruiting
- Votrient (pazopanib) / Novartis, BeiGene
Trial completion: Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment (clinicaltrials.gov) - Sep 26, 2013
P1, N=55, Completed, Sponsor: National Cancer Institute (NCI)
Completed --> Active, not recruiting Active, not recruiting --> Completed
- | Enrollment closed: Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor (clinicaltrials.gov) - Aug 29, 2013
P3, N=24, Active, not recruiting, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed Completed --> Active, not recruiting
- Zolinza (vorinostat) / Merck (MSD)
Trial completion: Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma (clinicaltrials.gov) - Jun 30, 2013
P1, N=20, Completed, Sponsor: National Cancer Institute (NCI)
Completed --> Active, not recruiting Active, not recruiting --> Completed
- RG4733 / Roche
Trial termination: Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia (clinicaltrials.gov) - Apr 30, 2013
P1/2, N=129, Terminated, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed Active, not recruiting --> Terminated
- Trial withdrawal: Studying Cerebrospinal Fluid Proteins and Angiogenesis Proteins in Young Patients With Newly Diagnosed Central Nervous System Tumors (clinicaltrials.gov) - Apr 17, 2013
P=N/A, N=0, Withdrawn, Sponsor: Pediatric Brain Tumor Consortium
Active, not recruiting --> Terminated Active, not recruiting --> Withdrawn
- Enrollment change: Studying Cerebrospinal Fluid Proteins and Angiogenesis Proteins in Young Patients With Newly Diagnosed Central Nervous System Tumors (clinicaltrials.gov) - Apr 17, 2013
P=N/A, N=0, Withdrawn, Sponsor: Pediatric Brain Tumor Consortium
Active, not recruiting --> Withdrawn N=99 --> 0
- sunitinib / Generic mfg.
Trial completion: Sunitinib in Treating Young Patients With Refractory Solid Tumors (clinicaltrials.gov) - Jan 13, 2013
P1, N=35, Completed, Sponsor: National Cancer Institute (NCI)
N=99 --> 0 Suspended --> Completed
- | Enrollment change: Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor (clinicaltrials.gov) - Dec 29, 2012
P3, N=24, Active, not recruiting, Sponsor: Children's Oncology Group
Suspended --> Completed N=225 --> 24
- Zolinza (vorinostat) / Merck (MSD)
Trial completion: Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors (clinicaltrials.gov) - Oct 23, 2012
P1, N=27, Completed, Sponsor: National Cancer Institute (NCI)
N=225 --> 24 Active, not recruiting --> Completed
- emvododstat (PTC299) / PTC Therap
Trial suspension: PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors (clinicaltrials.gov) - Apr 16, 2012
P1, N=30, Suspended, Sponsor: Pediatric Brain Tumor Consortium
Active, not recruiting --> Completed Recruiting --> Suspended