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8 Companies |
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6 Products |
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6 Products |
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0 Mechanisms of Action |
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12 Trials |
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66 News |
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- | Trial completion, Trial completion date, Trial primary completion date: Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (clinicaltrials.gov) - Apr 12, 2019
P=N/A, N=1314, Completed, Sponsor: Jonel Trebicka
Recruiting --> Completed | Trial completion date: Jul 2019 --> Oct 2018 | Trial primary completion date: Apr 2019 --> Jul 2018
- | Trial primary completion date: Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (clinicaltrials.gov) - Feb 8, 2019
P=N/A, N=1200, Recruiting, Sponsor: Jonel Trebicka
Recruiting --> Completed | Trial completion date: Jul 2019 --> Oct 2018 | Trial primary completion date: Apr 2019 --> Jul 2018 Trial primary completion date: Jul 2018 --> Apr 2019
- | Phase classification: Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With "Acute-on-chronic Liver Failure" (clinicaltrials.gov) - Feb 7, 2019
P=N/A, N=12, Completed, Sponsor: Instituto Grifols, S.A.
Trial primary completion date: Jul 2018 --> Apr 2019 Phase classification: P4 --> P=N/A
- | Enrollment change, Trial withdrawal: To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF). (clinicaltrials.gov) - Dec 3, 2018
P=N/A, N=0, Withdrawn, Sponsor: Institute of Liver and Biliary Sciences, India
Phase classification: P4 --> P=N/A N=188 --> 0 | Recruiting --> Withdrawn
- | Trial completion: Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure. (clinicaltrials.gov) - Nov 23, 2018
P=N/A, N=64, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
N=188 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed
- | Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Acute-On-Chronic Liver Failure in Zagazig University Hospitals (clinicaltrials.gov) - Aug 14, 2018
P=N/A, N=300, Completed, Sponsor: Zagazig University
Recruiting --> Completed Recruiting --> Completed | N=100 --> 300 | Trial completion date: Feb 2018 --> Aug 2018 | Trial primary completion date: Feb 2018 --> Aug 2018
- | Trial completion date, Trial suspension, Trial primary completion date: Clinical Features and Natural History of Acute-on-Chronic Liver Failure in Korean Patients With Chronic Liver Disease (clinicaltrials.gov) - Jul 18, 2018
P=N/A, N=1520, Suspended, Sponsor: Chuncheon Sacred Heart Hospital
Recruiting --> Completed | N=100 --> 300 | Trial completion date: Feb 2018 --> Aug 2018 | Trial primary completion date: Feb 2018 --> Aug 2018 Trial completion date: Jun 2017 --> Dec 2018 | Recruiting --> Suspended | Trial primary completion date: Jun 2017 --> Dec 2018
- | Biomarker, Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Exploring Biomarkers Predicting the Outcome of Acute-on-chronic Liver Failure (clinicaltrials.gov) - Jun 6, 2018
P=N/A, N=350, Completed, Sponsor: First Affiliated Hospital of Zhejiang University
Trial completion date: Jun 2017 --> Dec 2018 | Recruiting --> Suspended | Trial primary completion date: Jun 2017 --> Dec 2018 Not yet recruiting --> Completed | N=200 --> 350 | Trial completion date: Jul 2017 --> Jun 2018 | Trial primary completion date: May 2017 --> Oct 2017
- | Trial completion, Trial completion date, Trial primary completion date, IO biomarker, Immunomodulating: To Study the Immunomodulating Effects and Safety Profile of ?3 and ?6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure (clinicaltrials.gov) - Feb 27, 2018
P=N/A, N=90, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Not yet recruiting --> Completed | N=200 --> 350 | Trial completion date: Jul 2017 --> Jun 2018 | Trial primary completion date: May 2017 --> Oct 2017 Recruiting --> Completed | Trial completion date: Dec 2017 --> Dec 2017 | Trial primary completion date: Dec 2017 --> Dec 2017
- | Trial completion date, Trial primary completion date: Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (clinicaltrials.gov) - Feb 12, 2018
P=N/A, N=1200, Recruiting, Sponsor: Jonel Trebicka
Recruiting --> Completed | Trial completion date: Dec 2017 --> Dec 2017 | Trial primary completion date: Dec 2017 --> Dec 2017 Trial primary completion date: Dec 2017 --> Jul 2018 | Trial completion date: Dec 2018 --> Jul 2019
- | meropenem / Generic mfg.
Enrollment change, Trial completion date, Trial termination, Trial primary completion date: To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute Phase (clinicaltrials.gov) - Feb 6, 2018
P=N/A, N=14, Terminated, Sponsor: Institute of Liver and Biliary Sciences, India
Trial primary completion date: Dec 2017 --> Jul 2018 | Trial completion date: Dec 2018 --> Jul 2019 N=80 --> 14 | Recruiting --> Terminated | Trial primary completion date: Dec 2017 --> Jul 2017 | Trial completion date: Dec 2017 --> Jul 2017
- | Enrollment change, Trial completion date, Trial primary completion date: Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure. (clinicaltrials.gov) - Feb 6, 2018
P=N/A, N=64, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
N=80 --> 14 | Recruiting --> Terminated | Trial primary completion date: Dec 2017 --> Jul 2017 | Trial completion date: Dec 2017 --> Jul 2017 N=130 --> 64 | Trial completion date: Dec 2017 --> Feb 2018 | Trial primary completion date: Dec 2017 --> Feb 2018
- | meropenem / Generic mfg.
Trial primary completion date: To Study the Influence of GCSF on Natural History of Acute On Chronic Liver Failure After the Acute Phase (clinicaltrials.gov) - Nov 29, 2017
P=N/A, N=80, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
N=130 --> 64 | Trial completion date: Dec 2017 --> Feb 2018 | Trial primary completion date: Dec 2017 --> Feb 2018 Trial primary completion date: May 2017 --> Dec 2017
- | Enrollment change, Trial withdrawal: To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis. (clinicaltrials.gov) - Nov 28, 2017
P=N/A, N=0, Withdrawn, Sponsor: Institute of Liver and Biliary Sciences, India
Trial primary completion date: May 2017 --> Dec 2017 N=100 --> 0 | Recruiting --> Withdrawn
- | Trial completion, Trial primary completion date: Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure. (clinicaltrials.gov) - Nov 28, 2017
P=N/A, N=80, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
N=100 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed | Trial primary completion date: Aug 2017 --> Jan 2017
- | Trial primary completion date: Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure. (clinicaltrials.gov) - Jun 12, 2017
P=N/A, N=80, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Recruiting --> Completed | Trial primary completion date: Aug 2017 --> Jan 2017 Trial primary completion date: Mar 2017 --> Aug 2017
- | New trial: Acute-On-Chronic Liver Failure in Zagazig University Hospitals (clinicaltrials.gov) - Jun 12, 2017
P=N/A, N=100, Recruiting, Sponsor: Zagazig University
- | Trial primary completion date: Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure. (clinicaltrials.gov) - Jun 9, 2017
P=N/A, N=130, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Trial primary completion date: Mar 2017 --> Aug 2017 Trial primary completion date: Feb 2017 --> Dec 2017
- | New trial: To Assess the Efficacy of High-Volume Plasma Exchange and GCSF Versus GCSF Alone in Patients of Acute on Chronic Liver Failure (ACLF). (clinicaltrials.gov) - May 22, 2017
P=N/A, N=188, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
- | Enrollment open: Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (clinicaltrials.gov) - Apr 5, 2017
P=N/A, N=1200, Recruiting, Sponsor: Jonel Trebicka
Trial primary completion date: Feb 2017 --> Dec 2017 Active, not recruiting --> Recruiting
- | Enrollment closed: Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (clinicaltrials.gov) - Mar 19, 2017
P=N/A, N=1200, Active, not recruiting, Sponsor: Jonel Trebicka
Active, not recruiting --> Recruiting Not yet recruiting --> Active, not recruiting
- | New trial: Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (clinicaltrials.gov) - Feb 17, 2017
P=N/A, N=1200, Not yet recruiting, Sponsor: Jonel Trebicka
- Trial completion: To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure (clinicaltrials.gov) - Jan 31, 2017
P=N/A, N=120, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Not yet recruiting --> Active, not recruiting Recruiting --> Completed
- Biomarker, Trial primary completion date: Exploring Biomarkers Predicting the Outcome of Acute-on-chronic Liver Failure (clinicaltrials.gov) - Dec 16, 2016
P=N/A, N=200, Not yet recruiting, Sponsor: First Affiliated Hospital of Zhejiang University
Recruiting --> Completed Trial primary completion date: Dec 2016 --> May 2017
- Biomarker, New trial: Exploring Biomarkers Predicting the Outcome of Acute-on-chronic Liver Failure (clinicaltrials.gov) - Nov 16, 2016
P=N/A, N=200, Not yet recruiting, Sponsor: First Affiliated Hospital of Zhejiang University
- Trial completion: Assessment of Coagulation Profile and Haematopoietic Responses in Patients With Acute-on-chronic Liver Failure During Systemic Inflammatory Response (SIRS) and Sepsis (clinicaltrials.gov) - Aug 19, 2016
P=N/A, N=114, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Trial primary completion date: Dec 2016 --> May 2017 Recruiting --> Completed
- Enrollment open, IO biomarker, Immunomodulating: To Study the Immunomodulating Effects and Safety Profile of ?3 and ?6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure (clinicaltrials.gov) - Mar 25, 2016
P=N/A, N=80, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open: Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure. (clinicaltrials.gov) - Mar 24, 2016
P=N/A, N=130, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- New trial, IO biomarker, Immunomodulating: To Study the Immunomodulating Effects and Safety Profile of ?3 and ?6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure (clinicaltrials.gov) - Feb 25, 2016
P=N/A, N=80, Not yet recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
- New trial: Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure. (clinicaltrials.gov) - Feb 23, 2016
P=N/A, N=130, Not yet recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
- Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Trial completion, Enrollment change: Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy. (clinicaltrials.gov) - Feb 17, 2016
P=N/A, N=73, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Not yet recruiting --> Recruiting Recruiting --> Completed | N=50 --> 73
- Enrollment open: To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure (clinicaltrials.gov) - Jan 20, 2016
P=N/A, N=120, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Recruiting --> Completed | N=50 --> 73 Not yet recruiting --> Recruiting
- Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Trial primary completion date: Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy. (clinicaltrials.gov) - Jan 18, 2016
P=N/A, N=50, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Not yet recruiting --> Recruiting Trial primary completion date: Oct 2015 --> Jan 2016
- New trial: Clinical Features and Natural History of Acute-on-Chronic Liver Failure in Korean Patients With Chronic Liver Disease (clinicaltrials.gov) - Jan 11, 2016
P=N/A, N=1520, Recruiting, Sponsor: Chuncheon Sacred Heart Hospital
- New trial: To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure (clinicaltrials.gov) - Oct 23, 2015
P=N/A, N=120, Not yet recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
- Trial completion, Enrollment change, Trial primary completion date: Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). (clinicaltrials.gov) - Sep 29, 2015
P=N/A, N=24, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Trial primary completion date: Oct 2015 --> Jan 2016 Active, not recruiting --> Completed | N=256 --> 24 | Trial primary completion date: Aug 2015 --> Jan 2015
- Trial completion, Enrollment change: Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With "Acute-on-chronic Liver Failure" (clinicaltrials.gov) - Jun 16, 2015
P4, N=12, Completed, Sponsor: Joan Albert Arnaiz
Active, not recruiting --> Completed | N=256 --> 24 | Trial primary completion date: Aug 2015 --> Jan 2015 Recruiting --> Completed | N=10 --> 12
- New trial: Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure. (clinicaltrials.gov) - Jun 10, 2015
P=N/A, N=80, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
- New trial: To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis. (clinicaltrials.gov) - Jun 8, 2015
P=N/A, N=100, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
- Enrollment closed, Trial primary completion date: Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). (clinicaltrials.gov) - May 7, 2015
P=N/A, N=256, Active, not recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Recruiting --> Completed | N=10 --> 12 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Aug 2015
- emricasan (IDN 6556) / Histogen, Amerimmune
Enrollment change, Trial termination: Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF (clinicaltrials.gov) - Apr 30, 2015
P2, N=23, Terminated, Sponsor: Conatus Pharmaceuticals Inc.
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Aug 2015 N=60 --> 23 | Active, not recruiting --> Terminated; Data needs met
- Trial completion, Enrollment change, Trial primary completion date: Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure (clinicaltrials.gov) - Apr 10, 2015
P=N/A, N=522, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
N=60 --> 23 | Active, not recruiting --> Terminated; Data needs met Recruiting --> Completed | N=300 --> 522 | Trial primary completion date: Jun 2015 --> Nov 2014
- Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Clinical: Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy. (clinicaltrials.gov) - Dec 22, 2014
P=N/A, N=50, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
- Clinical: Assessment of Coagulation Profile and Haematopoietic Responses in Patients With Acute-on-chronic Liver Failure During Systemic Inflammatory Response (SIRS) and Sepsis (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=100, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
- ||| emricasan (IDN 6556) / Histogen, Amerimmune
Enrollment closed, Trial primary completion date: Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF (clinicaltrials.gov) - Oct 2, 2014
P2, N=60, Active, not recruiting, Sponsor: Conatus Pharmaceuticals Inc.
Recruiting --> Completed | N=300 --> 522 | Trial primary completion date: Jun 2015 --> Nov 2014 Recruiting --> Active, not recruiting | Trial primary completion date: Aug 2014 --> Nov 2014
- Enrollment open: Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). (clinicaltrials.gov) - May 6, 2014
P=N/A, N=256, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Recruiting --> Active, not recruiting | Trial primary completion date: Aug 2014 --> Nov 2014 Not yet recruiting --> Recruiting
- Enrollment open: Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver Failure (clinicaltrials.gov) - Apr 16, 2014
P=N/A, N=300, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial initiation date: Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). (clinicaltrials.gov) - Apr 1, 2014
P=N/A, N=256, Not yet recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Not yet recruiting --> Recruiting Initiation date: Oct 2013 --> Apr 2014
- | Enrollment change: Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure (clinicaltrials.gov) - Apr 1, 2014
P3, N=55, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Initiation date: Oct 2013 --> Apr 2014 N=100 --> 55
- | Trial completion: Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure (clinicaltrials.gov) - Apr 1, 2014
P3, N=55, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
N=100 --> 55 Recruiting --> Completed