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- |||||||||| New P3 trial, Surgery: Efficacy and Safety in a Randomised Acute Pain Study of MR308: STARDOM2. (clinicaltrials.gov) - Feb 23, 2017
P3, N=1100, Not yet recruiting, Sponsor: Mundipharma Research GmbH & Co KG
- | Trial primary completion date: The Calmer Project (clinicaltrials.gov) - Feb 23, 2017
P=N/A, N=60, Recruiting, Sponsor: Children's & Women's Health Centre of British Columbia
Trial primary completion date: Jan 2017 --> Aug 2017
- |||| Trial primary completion date: Capsaicin + Diclofenac Gel in Acute Back Pain or Neck Pain (clinicaltrials.gov) - Feb 23, 2017
P3, N=800, Recruiting, Sponsor: Boehringer Ingelheim
Trial primary completion date: Jan 2017 --> Aug 2017 Trial primary completion date: Apr 2017 --> Sep 2017
- Enrollment open: Tactile Acuity in Experimentally Induced Acute Low Back Pain (clinicaltrials.gov) - Feb 11, 2017
P=N/A, N=57, Recruiting, Sponsor: The Jerzy Kukuczka Academy of Physical Education in Katowice
Trial primary completion date: Apr 2017 --> Sep 2017 Not yet recruiting --> Recruiting
- New trial, Surgery: Effect of Nerve Block Versus General Anaesthesia for Distal Radial Fracture Surgery (clinicaltrials.gov) - Feb 9, 2017
P=N/A, N=70, Active, not recruiting, Sponsor: The University of Hong Kong
- Exparel (bupivacaine liposome injectable suspension) / Pacira
Enrollment open: Single Ascending Dose Study of Two Liquidia Bupivacaine Formulations (clinicaltrials.gov) - Feb 7, 2017
P1, N=36, Recruiting, Sponsor: Liquidia Technologies, Inc.
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- New trial: Electronic Defaults to Reduce Opioid Prescribing in Dentistry Practices (clinicaltrials.gov) - Jan 26, 2017
P=N/A, N=10000, Enrolling by invitation, Sponsor: Montefiore Medical Center
- pregabalin / Generic mfg.
Enrollment closed, Trial primary completion date: Prophylactic Pregabalin to Decrease Pain During Medical Abortion (clinicaltrials.gov) - Jan 23, 2017
P4, N=110, Active, not recruiting, Sponsor: University of Hawaii
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Mar 2017
- |||| ibuprofen / Generic mfg.
Trial completion: Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD). (clinicaltrials.gov) - Jan 19, 2017
P1/2, N=96, Completed, Sponsor: Spherium Biomed
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Mar 2017 Recruiting --> Completed
- | ketorolac / Generic mfg.
Trial completion: Sprix: An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain (clinicaltrials.gov) - Jan 18, 2017
P=N/A, N=30, Completed, Sponsor: The Cleveland Clinic
Recruiting --> Completed Active, not recruiting --> Completed
- tramadol hydrochloride / Generic mfg.
Trial primary completion date, Surgery: Immune Response of Caudally Administrated Tramadol In Pediatric Lower Abdominal Surgery (clinicaltrials.gov) - Jan 18, 2017
P2, N=60, Recruiting, Sponsor: Assiut University
Active, not recruiting --> Completed Trial primary completion date: Dec 2016 --> Mar 2017
- New trial: Tactile Acuity in Experimentally Induced Acute Low Back Pain (clinicaltrials.gov) - Jan 13, 2017
P=N/A, N=57, Not yet recruiting, Sponsor: The Jerzy Kukuczka Academy of Physical Education in Katowice
- |||||| celecoxib oral / Generic mfg.
Enrollment open: STARDOM1: Efficacy and Safety in a Randomised Acute Pain Study of MR308 (Tramadol/Celecoxib). (clinicaltrials.gov) - Jan 4, 2017
P3, N=765, Recruiting, Sponsor: Mundipharma Research GmbH & Co KG
Trial primary completion date: Dec 2016 --> Mar 2017 Not yet recruiting --> Recruiting
- Enrollment closed: DASAU: Comparative Study on Acute Pain Evaluation Between Spanish and French Hospital Emergency Unit (clinicaltrials.gov) - Jan 4, 2017
P=N/A, N=641, Active, not recruiting, Sponsor: Groupe Hospitalier Paris Saint Joseph
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- || New P2/3 trial, Surgery: Perioperative Epidural Versus Intravenous Local Anesthetic Infusion in Open Upper Abdominal Surgery (clinicaltrials.gov) - Dec 28, 2016
P2/3, N=70, Not yet recruiting, Sponsor: Assiut University
- New trial: Electronic Defaults to Reduce Opioid Prescribing in Emergency Department and Primary Care Settings (clinicaltrials.gov) - Dec 27, 2016
P=N/A, N=15000, Enrolling by invitation, Sponsor: Montefiore Medical Center
- Exparel (bupivacaine liposome injectable suspension) / Pacira
Trial completion, Enrollment change, Surgery: Comparison of Epidural and TAP Block in Abdominal Surgery (clinicaltrials.gov) - Dec 19, 2016
P=N/A, N=72, Completed, Sponsor: University of Nebraska
Recruiting --> Active, not recruiting Recruiting --> Completed | N=100 --> 72
- | New P4 trial: 40%D-N-PP: 40% Orally Administered Dextrose Gel is More Effective Than 25% Dextrose (clinicaltrials.gov) - Dec 5, 2016
P4, N=200, Completed, Sponsor: University of Targu Mures, Romania
- | Exparel (bupivacaine liposome injectable suspension) / Pacira
New P1 trial: Single Ascending Dose Study of Two Liquidia Bupivacaine Formulations (clinicaltrials.gov) - Dec 5, 2016
P1, N=36, Not yet recruiting, Sponsor: Liquidia Technologies, Inc.
- |||||||||| celecoxib oral / Generic mfg.
New P3 trial: STARDOM1: Efficacy and Safety in a Randomised Acute Pain Study of MR308 (Tramadol/Celecoxib). (clinicaltrials.gov) - Dec 4, 2016
P3, N=765, Not yet recruiting, Sponsor: Mundipharma Research GmbH & Co KG
- New trial: Pain Evaluation and Treatment in the Emergency Department (clinicaltrials.gov) - Dec 2, 2016
P=N/A, N=32000, Recruiting, Sponsor: University Hospital, Geneva
- New trial: DREAM-P: Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: a Pilot Study (clinicaltrials.gov) - Nov 30, 2016
P=N/A, N=20, Not yet recruiting, Sponsor: St. Justine's Hospital
- morphine sulphate / Generic mfg.
Trial initiation date, Trial primary completion date: DREAM-T: Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial (clinicaltrials.gov) - Nov 25, 2016
P=N/A, N=40, Not yet recruiting, Sponsor: St. Justine's Hospital
Recruiting --> Completed | N=100 --> 72 Initiation date: Dec 2016 --> Dec 2017 | Trial primary completion date: Dec 2018 --> Dec 2019
- New trial: DASAU: Comparative Study on Acute Pain Evaluation Between Spanish and French Hospital Emergency Unit (clinicaltrials.gov) - Nov 25, 2016
P=N/A, N=641, Recruiting, Sponsor: Groupe Hospitalier Paris Saint Joseph
- New trial: Effects of Photobiomodulation Therapy (PBMT) in Total Hip Arthroplasty (clinicaltrials.gov) - Nov 22, 2016
P=N/A, N=18, Recruiting, Sponsor: Adriane Aver Vanin
- New trial, Surgery: Evaluation of a Breast Biblock Analgesia for the Mastectomy With Radical Axillary Lymphadenectomy Surgery (clinicaltrials.gov) - Nov 14, 2016
P=N/A, N=9, Completed, Sponsor: Maison de Sant
- tramadol hydrochloride / Generic mfg.
Trial initiation date, Trial primary completion date, Surgery: Immune Response of Caudally Administrated Tramadol In Pediatric Lower Abdominal Surgery (clinicaltrials.gov) - Nov 8, 2016
P2, N=60, Recruiting, Sponsor: Assiut University
Initiation date: Dec 2016 --> Dec 2017 | Trial primary completion date: Dec 2018 --> Dec 2019 Initiation date: Mar 2016 --> Jun 2016 | Trial primary completion date: Jun 2016 --> Dec 2016
- hydrocodone and acetaminophen (MNK-155) / Mallinckrodt
Enrollment change, Trial withdrawal: Pharmacokinetics and Safety of MNK-155 in Postsurgical Adolescent Subjects With Moderate to Severe Acute Pain (clinicaltrials.gov) - Nov 8, 2016
P1, N=0, Withdrawn, Sponsor: Mallinckrodt
Initiation date: Mar 2016 --> Jun 2016 | Trial primary completion date: Jun 2016 --> Dec 2016 N=48 --> 0 | Recruiting --> Withdrawn
- ||| Subsys (fentanyl sublingual spray) / Insys Therap
Trial initiation date, Trial primary completion date: Study to Explore Effectiveness of Sublingual Fentanyl Spray in Emergency Department Patients With Acute Pain (clinicaltrials.gov) - Oct 31, 2016
P2, N=176, Not yet recruiting, Sponsor: INSYS Therapeutics Inc
N=48 --> 0 | Recruiting --> Withdrawn Initiation date: Oct 2016 --> Jun 2017 | Trial primary completion date: Apr 2017 --> Dec 2017
- | Trial initiation date: PAIN-K: Prehospital Analgesia With Intra-Nasal Ketamine (clinicaltrials.gov) - Oct 28, 2016
P4, N=40, Not yet recruiting, Sponsor: University of British Columbia
Initiation date: Oct 2016 --> Jun 2017 | Trial primary completion date: Apr 2017 --> Dec 2017 Initiation date: May 2016 --> Dec 2016
- morphine sulphate / Generic mfg.
New trial: DREAM-T: Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial (clinicaltrials.gov) - Oct 27, 2016
P=N/A, N=40, Not yet recruiting, Sponsor: St. Justine's Hospital
- Trial completion, Surgery: Paravertebral Catheters for Pancreatic Surgery (clinicaltrials.gov) - Oct 27, 2016
P=N/A, N=50, Completed, Sponsor: University of Minnesota - Clinical and Translational Science Institute
Initiation date: May 2016 --> Dec 2016 Recruiting --> Completed
- Exparel (bupivacaine liposome injectable suspension) / Pacira
Enrollment open, Trial initiation date, Trial primary completion date: TAP vs Surgical Infiltration of Local Anesthetic in Laparoscopic and Robotic Hysterectomy (clinicaltrials.gov) - Oct 27, 2016
P4, N=60, Recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting --> Completed Not yet recruiting --> Recruiting | Initiation date: Sep 2015 --> Jul 2016 | Trial primary completion date: Aug 2016 --> Dec 2016
- dexamethasone injection / Generic mfg.
Trial completion, Trial primary completion date: Dexamethasone and Pain Following Total Knee Arthroplasty (clinicaltrials.gov) - Oct 21, 2016
P4, N=45, Completed, Sponsor: Duke University
Not yet recruiting --> Recruiting | Initiation date: Sep 2015 --> Jul 2016 | Trial primary completion date: Aug 2016 --> Dec 2016 Enrolling by invitation --> Completed | Trial primary completion date: Sep 2016 --> Jan 2016
- || ibuprofen / Generic mfg.
Trial primary completion date: Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD). (clinicaltrials.gov) - Oct 14, 2016
P1/2, N=96, Recruiting, Sponsor: Spherium Biomed
Enrolling by invitation --> Completed | Trial primary completion date: Sep 2016 --> Jan 2016 Trial primary completion date: Sep 2016 --> Dec 2016
- New P2/3 trial: Intranasal Ketamine as a Sedative for Venipuncture (clinicaltrials.gov) - Oct 11, 2016
P2/3, N=39, Completed, Sponsor: Hospital de Clinicas de Porto Alegre
- | New P4 trial, Surgery: Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients (clinicaltrials.gov) - Oct 5, 2016
P4, N=120, Recruiting, Sponsor: Washington University School of Medicine
- |||||| Enrollment open, Trial primary completion date: Study to Evaluate the Overall Performance of the Zalviso System (clinicaltrials.gov) - Sep 29, 2016
P3, N=315, Recruiting, Sponsor: AcelRx Pharmaceuticals, Inc.
Trial primary completion date: Sep 2016 --> Dec 2016 Not yet recruiting --> Recruiting | Trial primary completion date: Mar 2017 --> Jul 2017
- Trial completion, Trial primary completion date, Surgery: Interscalene Brachial Plexus Block to Treat Pain After Clavicular Surgery (clinicaltrials.gov) - Sep 27, 2016
P4, N=50, Completed, Sponsor: Centre Hospitalier Universitaire Vaudois
Not yet recruiting --> Recruiting | Trial primary completion date: Mar 2017 --> Jul 2017 Recruiting --> Completed | Trial primary completion date: Sep 2017 --> Aug 2016
- New trial: Is There an Ideal Dose of Intravenous Fentanyl in the Prehospital Setting (clinicaltrials.gov) - Sep 26, 2016
P=N/A, N=7093, Not yet recruiting, Sponsor: University of Aarhus
- ||||||| Trial completion, Enrollment change: Open-Label Safety and Efficacy of the Sufentanil Sublingual Tablet 30 mcg for Acute Pain (clinicaltrials.gov) - Sep 23, 2016
P3, N=76, Completed, Sponsor: AcelRx Pharmaceuticals, Inc.
Recruiting --> Completed | Trial primary completion date: Sep 2017 --> Aug 2016 Recruiting --> Completed | N=120 --> 76
- ||| New trial, Adverse events: Observational Prospective Study to Evaluate AEs, Risk Factors and Drug Utilization of BUSCAPINA COMPOSITUM N in Adults From Metropolitan Lima (clinicaltrials.gov) - Sep 21, 2016
P=N/A, N=360, Not yet recruiting, Sponsor: Boehringer Ingelheim
- ketamine / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Ketamine Patient-Controlled Analgesia for Acute Pain (clinicaltrials.gov) - Aug 31, 2016
P3, N=20, Terminated, Sponsor: University of Cincinnati
Recruiting --> Completed | N=120 --> 76 N=30 --> 20 | Enrolling by invitation --> Terminated | Trial primary completion date: Apr 2017 --> Jun 2016; Withdrawals from study due to anticipated effects from study drugs
- || ibuprofen / Generic mfg.
Trial primary completion date: Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD). (clinicaltrials.gov) - Aug 8, 2016
P1/2, N=96, Recruiting, Sponsor: Spherium Biomed
N=30 --> 20 | Enrolling by invitation --> Terminated | Trial primary completion date: Apr 2017 --> Jun 2016; Withdrawals from study due to anticipated effects from study drugs Trial primary completion date: Mar 2016 --> Sep 2016
- New trial: Efficacy of Gabapentin vs. Placebo for Adjuvant Pain Control Following Acute Rib Fractures (clinicaltrials.gov) - Aug 5, 2016
P0, N=500, Not yet recruiting, Sponsor: Denver Health and Hospital Authority
- remifentanil / Generic mfg.
New trial: The Effect of Ultra-low-dose Naloxone on Remifentanil-induced Postoperative Hyperalgesia - A Randomized Controlled Study (clinicaltrials.gov) - Aug 4, 2016
P=N/A, N=92, Completed, Sponsor: Seoul National University Hospital
- Trial completion, Surgery: PREDO: Study to Test the Value of a Pain Modulation Test in Predicting Persistent Postoperative Pain After Breast Cancer Surgery (clinicaltrials.gov) - Aug 1, 2016
P=N/A, N=200, Completed, Sponsor: University Hospital, Geneva
Trial primary completion date: Mar 2016 --> Sep 2016 Active, not recruiting --> Completed
- New trial: Registry for Acute Pain Treatment (clinicaltrials.gov) - Jul 27, 2016
P=N/A, N=250000, Recruiting, Sponsor: University Hospital, Saarland
- pregabalin / Generic mfg., paclitaxel / Generic mfg.
Trial completion: Pregabalin in Preventing Acute Pain Syndrome in Patients Receiving Paclitaxel (clinicaltrials.gov) - Jul 23, 2016
P=N/A, N=46, Completed, Sponsor: Academic and Community Cancer Research United
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ketamine / Generic mfg.
Enrollment closed, Trial primary completion date, Surgery: Ketamine as Adjunctive Analgesic With Bupivacaine in Paravertebral Analgesia for Breast Cancer Surgery (clinicaltrials.gov) - Jul 14, 2016
P1/2, N=90, Active, not recruiting, Sponsor: Assiut University
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: May 2016 --> Dec 2016