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||||||||||  ibuprofen / Generic mfg.
Trial completion:  SNIF: Outcomes Associated With Application of a Normothermia Protocol in Patients With Severe Neurological Insult and Fever (clinicaltrials.gov) -  Jan 24, 2024
P=N/A, N=10, Completed,  Sponsor: University of Washington
Terminated --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion, Enrollment change:  Outcomes Following Neuropsychological Intervention in Acquired Brain Injury Outpatients With Executive Dysfunction (clinicaltrials.gov) -  Apr 25, 2019
P=N/A, N=18, Completed,  Sponsor: University of Manitoba
Terminated --> Completed Enrolling by invitation --> Completed | N=36 --> 18

|||||||||| Trial completion, Phase classification, Enrollment change: Rehabilitation of the Upper Extremity With Enhanced Proprioceptive Feedback Following Incomplete Spinal Cord Injury (clinicaltrials.gov) - Apr 20, 2019
P=N/A, N=13, Completed, Sponsor: Oregon Health and Science University
Enrolling by invitation --> Completed | N=36 --> 18 Active, not recruiting --> Completed | Phase classification: P1/2 --> PN/A | N=20 --> 13

|||||||||| Trial completion, Enrollment change: Restoration of Life Role Participation Through Cognitive and Motor Training for TBI (clinicaltrials.gov) - Apr 20, 2019
P=N/A, N=5, Completed, Sponsor: Malcom Randall VA Medical Center
Active, not recruiting --> Completed | Phase classification: P1/2 --> PN/A | N=20 --> 13 Active, not recruiting --> Completed | N=24 --> 5

|||||||||| Trial completion: Bowel Care and Cardiovascular Function After Spinal Cord Injury (clinicaltrials.gov) - Apr 20, 2019
P4, N=13, Completed, Sponsor: Simon Fraser University
Active, not recruiting --> Completed | N=24 --> 5 Recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion, Enrollment change, Trial primary completion date:  Comparison of Two Psycho-educational Family Group Interventions for Persons With SCI and Their Caregivers (clinicaltrials.gov) -  Apr 19, 2019
P=N/A, N=38, Completed,  Sponsor: St. Luke's Rehabilitation Institute
Recruiting --> Completed Active, not recruiting --> Completed | N=64 --> 38 | Trial primary completion date: Dec 2018 --> Apr 2019

||||||||||  NN1213 / Novo Nordisk
Trial completion, HEOR:  Health Outcomes After Locomotor Training in Spinal Cord Injury (clinicaltrials.gov) -  Apr 19, 2019
P=N/A, N=80, Completed,  Sponsor: Stony Brook University
Active, not recruiting --> Completed | N=64 --> 38 | Trial primary completion date: Dec 2018 --> Apr 2019 Recruiting --> Completed

|||||||||| Trial completion, Trial completion date, Metastases: Supraspinal Control of Lower Urinary Tract Function in Healthy Controls and Patients With Bladder Dysfunction (clinicaltrials.gov) - Mar 18, 2019
P=N/A, N=91, Completed, Sponsor: University of Zurich
Recruiting --> Completed Recruiting --> Completed | Trial completion date: Dec 2014 --> Dec 2018

|||||||||| Enrollment change, Trial termination: Evaluation of Tolerability and Efficacy of Erythropoietin (EPO) Treatment in Spinal Shock: Comparative Study Versus Methylprednisolone (MP) (clinicaltrials.gov) - Mar 14, 2019
P3, N=10, Terminated, Sponsor: Niguarda Hospital
Recruiting --> Completed | Trial completion date: Dec 2014 --> Dec 2018 N=100 --> 10 | Suspended --> Terminated; Italian Medicines Agency decision

||||||||||  NN1213 / Novo Nordisk
Trial completion, Enrollment change, Trial primary completion date:  Neurofeedback for Treatment of Central Neuropathic Pain (CNP) in Sub-acute Spinal Cord Injury (SCI) (clinicaltrials.gov) -  Mar 1, 2019
P=N/A, N=20, Completed,  Sponsor: NHS Greater Glasgow and Clyde
N=100 --> 10 | Suspended --> Terminated; Italian Medicines Agency decision Recruiting --> Completed | N=60 --> 20 | Trial primary completion date: Aug 2017 --> Nov 2017

||||||||||  NN1213 / Novo Nordisk
Trial completion:  MUBI: Efficacy and Neural Basis of Music-based Neurological Rehabilitation for Traumatic Brain Injury (clinicaltrials.gov) -  Feb 28, 2019
P=N/A, N=40, Completed,  Sponsor: Helsinki University
Recruiting --> Completed | N=60 --> 20 | Trial primary completion date: Aug 2017 --> Nov 2017 Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion, Trial completion date, Trial primary completion date:  Effect of Methylphenidate on Ecologic Function in Paediatric Acquired Brain Injury Population (clinicaltrials.gov) -  Feb 26, 2019
P2, N=34, Completed,  Sponsor: Loewenstein Hospital
Active, not recruiting --> Completed Recruiting --> Completed | Trial completion date: Dec 2017 --> Mar 2017 | Trial primary completion date: Dec 2017 --> Jan 2017

||||||||||  NN1213 / Novo Nordisk
Enrollment change:  Deployment Related Mild Traumatic Brain Injury (mTBI) (clinicaltrials.gov) -  Feb 25, 2019
P=N/A, N=750, Completed,  Sponsor: The Defense and Veterans Brain Injury Center
Recruiting --> Completed | Trial completion date: Dec 2017 --> Mar 2017 | Trial primary completion date: Dec 2017 --> Jan 2017 N=1500 --> 750

|||||||||| Trial completion: A Colonic Tube to Improve Bowel Function in Spinal Cord Injury (clinicaltrials.gov) - Feb 1, 2019
P=N/A, N=7, Completed, Sponsor: VA Office of Research and Development
N=1500 --> 750 Active, not recruiting --> Completed

|||||||||| Trial completion: Traumatic Brain Injury Among Homeless Veterans (clinicaltrials.gov) - Jan 31, 2019
P=N/A, N=2000, Completed, Sponsor: VA Eastern Colorado Health Care System
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion, Enrollment change:  Robotic-assisted Locomotor Training on Mobility and Cardiopulmonary Function in Patients Suffering From Spinal Cord Injury (clinicaltrials.gov) -  Jan 28, 2019
P=N/A, N=16, Completed,  Sponsor: Kowloon Hospital, Hong Kong
Active, not recruiting --> Completed Recruiting --> Completed | N=80 --> 16

||||||||||  NN1213 / Novo Nordisk
Enrollment change, Trial withdrawal:  Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel (clinicaltrials.gov) -  Jan 18, 2019
P=N/A, N=0, Withdrawn,  Sponsor: Uniformed Services University of the Health Sciences
Recruiting --> Completed | N=80 --> 16 N=150 --> 0 | Recruiting --> Withdrawn

||||||||||  NN1213 / Novo Nordisk
Trial completion:  Detection of Hemodynamic Changes in TBI Population With Functional Near Infrared Spectroscopy (clinicaltrials.gov) -  Jan 17, 2019
P=N/A, N=50, Completed,  Sponsor: Uniformed Services University of the Health Sciences
N=150 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed

|||||||||| Trial completion: Measure of Cerebrovascular Dysfunction After TBI With fNIRS (clinicaltrials.gov) - Jan 17, 2019
P=N/A, N=100, Completed, Sponsor: Uniformed Services University of the Health Sciences
Recruiting --> Completed Recruiting --> Completed

|||||||||| Trial completion: Hypothermia Following Acute Spinal Cord Injury (clinicaltrials.gov) - Jan 9, 2019
P=N/A, N=41, Completed, Sponsor: University of Miami
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Enrollment change, Trial completion date, Trial termination, Trial primary completion date: The Effect of tDCS on Subcortical Brain Functioning (clinicaltrials.gov) - Dec 21, 2018
P=N/A, N=3, Terminated, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed N=150 --> 3 | Trial completion date: Dec 2020 --> Oct 2018 | Enrolling by invitation --> Terminated | Trial primary completion date: Sep 2020 --> Oct 2018; Difficulty identifying appropriate patients

||||||||||  dexamethasone / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date:  DECS: Dexamethasone Versus Burr Hole Craniostomy for Symptomatic Chronic Subdural Hematoma (clinicaltrials.gov) -  Dec 11, 2018
P2/3, N=10, Terminated,  Sponsor: University of Virginia
N=150 --> 3 | Trial completion date: Dec 2020 --> Oct 2018 | Enrolling by invitation --> Terminated | Trial primary completion date: Sep 2020 --> Oct 2018; Difficulty identifying appropriate patients N=300 --> 10 | Recruiting --> Terminated | Trial primary completion date: Mar 2017 --> Dec 2017; Accrual too slow; Study P.I. passed away.

||||||||||  NN1213 / Novo Nordisk
Trial completion, Enrollment change:  TRAIN-TBI: Therapeutic Resources for Attention Improvement With Neuroimaging for TBI (clinicaltrials.gov) -  Dec 4, 2018
P=N/A, N=26, Completed,  Sponsor: University of California, San Francisco
N=300 --> 10 | Recruiting --> Terminated | Trial primary completion date: Mar 2017 --> Dec 2017; Accrual too slow; Study P.I. passed away. Recruiting --> Completed | N=60 --> 26

||||||||||  NN1213 / Novo Nordisk
Trial completion:  ProjectLIFT: Evaluation of a Telehealth Lifestyle Management Program to Improve Healthy Behaviors Post Head Injury (clinicaltrials.gov) -  Nov 29, 2018
P=N/A, N=79, Completed,  Sponsor: University of Alabama at Birmingham
Recruiting --> Completed | N=60 --> 26 Recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Enrollment closed, Trial completion date, Trial primary completion date:  EpoRepair: Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants (clinicaltrials.gov) -  Nov 23, 2018
P3, N=120, Active, not recruiting,  Sponsor: University of Zurich
Recruiting --> Completed Recruiting --> Active, not recruiting | Trial completion date: Dec 2021 --> Mar 2024 | Trial primary completion date: Feb 2021 --> Dec 2023

|||||||||| Phase classification: BIMA: mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms (clinicaltrials.gov) - Nov 21, 2018
P2, N=71, Completed, Sponsor: U.S. Army Medical Research and Materiel Command
Recruiting --> Active, not recruiting | Trial completion date: Dec 2021 --> Mar 2024 | Trial primary completion date: Feb 2021 --> Dec 2023 Phase classification: P=N/A --> P2

||||||||||  NN1213 / Novo Nordisk
Enrollment change, Trial completion date, Trial termination:  Written Versus Verbal Education for Mild Traumatic Brain Injury (clinicaltrials.gov) -  Nov 15, 2018
P=N/A, N=12, Terminated,  Sponsor: University of British Columbia
Phase classification: P=N/A --> P2 N=80 --> 12 | Trial completion date: Dec 2015 --> Apr 2016 | Recruiting --> Terminated; Low enrollment

|||||||||| Trial termination: AC105 in Patients With Acute Traumatic Spinal Cord Injury (clinicaltrials.gov) - Nov 6, 2018
P2, N=15, Terminated, Sponsor: Acorda Therapeutics
N=80 --> 12 | Trial completion date: Dec 2015 --> Apr 2016 | Recruiting --> Terminated; Low enrollment Completed --> Terminated; The study was terminated by the Sponsor due to insufficient enrollment.

||||||||||  NN1213 / Novo Nordisk
Enrollment change, Trial withdrawal:  Safety and Efficacy of Stem Cell Therapy in Spinal Cord Injury (clinicaltrials.gov) -  Oct 25, 2018
P1, N=0, Withdrawn,  Sponsor: Neurogen Brain and Spine Institute
Completed --> Terminated; The study was terminated by the Sponsor due to insufficient enrollment. N=166 --> 0 | Completed --> Withdrawn

||||||||||  NN1213 / Novo Nordisk
Enrollment change, Trial withdrawal:  Stem Cell Therapy in Traumatic Brain Injury (clinicaltrials.gov) -  Oct 25, 2018
P1, N=0, Withdrawn,  Sponsor: Neurogen Brain and Spine Institute
N=166 --> 0 | Completed --> Withdrawn N=43 --> 0 | Completed --> Withdrawn

||||||||||  NN1213 / Novo Nordisk
Enrollment change, Trial withdrawal:  Stem Cell Therapy in Spinal Cord Injury (clinicaltrials.gov) -  Oct 25, 2018
P2, N=0, Withdrawn,  Sponsor: Neurogen Brain and Spine Institute
N=43 --> 0 | Completed --> Withdrawn N=500 --> 0 | Recruiting --> Withdrawn

||||||||||  NN1213 / Novo Nordisk
Enrollment change, Trial completion date, Trial termination, Trial primary completion date:  Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI (clinicaltrials.gov) -  Oct 4, 2018
P2, N=11, Terminated,  Sponsor: Uniformed Services University of the Health Sciences
N=30 --> 11 | Trial completion date: Jun 2017 --> Aug 2018 | Not yet recruiting --> Terminated | Trial primary completion date: Jun 2015 --> Aug 2018; Recruitment was slower than anticipated. Incomplete neuropsychological outcome measures obtained.

||||||||||  alendronate / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date:  Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury (SCI) Previously Treated With Teriparatide (clinicaltrials.gov) -  Sep 26, 2018
P2, N=17, Completed,  Sponsor: Northwestern University
Incomplete neuropsychological outcome measures obtained. Active, not recruiting --> Completed | Trial completion date: Jun 2018 --> Aug 2016 | Trial primary completion date: Dec 2017 --> Aug 2016

||||||||||  NN1213 / Novo Nordisk
Trial completion, Enrollment change:  12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI) (clinicaltrials.gov) -  Sep 25, 2018
P2, N=25, Completed,  Sponsor: Northwestern University
Active, not recruiting --> Completed | Trial completion date: Jun 2018 --> Aug 2016 | Trial primary completion date: Dec 2017 --> Aug 2016 Active, not recruiting --> Completed | N=40 --> 25

|||||||||| Trial completion, Enrollment change, Trial completion date: A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial (clinicaltrials.gov) - Sep 11, 2018
P=N/A, N=24, Completed, Sponsor: Vanderbilt University
Active, not recruiting --> Completed | N=40 --> 25 Active, not recruiting --> Completed | N=130 --> 24 | Trial completion date: Dec 2020 --> Dec 2015

|||||||||| Phase classification: Growth Hormone and Brain Functioning After Traumatic Brain Injury (clinicaltrials.gov) - Sep 10, 2018
P1, N=15, Completed, Sponsor: Joe Springer
Active, not recruiting --> Completed | N=130 --> 24 | Trial completion date: Dec 2020 --> Dec 2015 Phase classification: P4 --> P1

|||||||||| Trial completion, Enrollment change: The EPIC Project: Impact of Implementing the EMS Traumatic Brain Injury Treatment Guidelines (clinicaltrials.gov) - Aug 28, 2018
P=N/A, N=26873, Completed, Sponsor: University of Arizona
Phase classification: P4 --> P1 Recruiting --> Completed | N=20000 --> 26873

||||||||||  NN1213 / Novo Nordisk
Trial completion, Trial completion date, Trial primary completion date:  Normative Datasets for Assessments Planned for Mild Traumatic Brain Injury (NORMAL) (clinicaltrials.gov) -  Aug 27, 2018
P=N/A, N=83, Completed,  Sponsor: Lindell Weaver
Recruiting --> Completed | N=20000 --> 26873 Active, not recruiting --> Completed | Trial completion date: Feb 2017 --> Jan 2016 | Trial primary completion date: Feb 2017 --> Jan 2016

|||||||||| Trial completion: POLAR-RCT: The Prophylactic Hypothermia Trial to Lessen Traumatic Brain Injury (clinicaltrials.gov) - Aug 22, 2018
P=N/A, N=511, Completed, Sponsor: Australian and New Zealand Intensive Care Research Centre
Active, not recruiting --> Completed | Trial completion date: Feb 2017 --> Jan 2016 | Trial primary completion date: Feb 2017 --> Jan 2016 Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  Repetitive Transcranial Magnetic Stimulation in Individuals With Spinal Cord Injury: A Pilot Study (clinicaltrials.gov) -  Aug 16, 2018
P=N/A, N=8, Completed,  Sponsor: McMaster University
Active, not recruiting --> Completed Not yet recruiting --> Completed | N=20 --> 8 | Trial completion date: Dec 2015 --> Feb 2017 | Trial primary completion date: Aug 2015 --> Jan 2017

|||||||||| Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Use of a Traumatic Brain Injury (TBI) Screen in a Veteran Mental Health Population (clinicaltrials.gov) - Aug 14, 2018
P=N/A, N=1810, Completed, Sponsor: VA Eastern Colorado Health Care System
Not yet recruiting --> Completed | N=20 --> 8 | Trial completion date: Dec 2015 --> Feb 2017 | Trial primary completion date: Aug 2015 --> Jan 2017 Active, not recruiting --> Completed | N=3000 --> 1810 | Trial completion date: Dec 2016 --> Aug 2016 | Trial primary completion date: Dec 2016 --> Aug 2016

||||||||||  NN1213 / Novo Nordisk
Enrollment closed, Enrollment change, Trial completion date:  MUBI: Efficacy and Neural Basis of Music-based Neurological Rehabilitation for Traumatic Brain Injury (clinicaltrials.gov) -  Aug 13, 2018
P=N/A, N=40, Active, not recruiting,  Sponsor: Helsinki University
Active, not recruiting --> Completed | N=3000 --> 1810 | Trial completion date: Dec 2016 --> Aug 2016 | Trial primary completion date: Dec 2016 --> Aug 2016 Recruiting --> Active, not recruiting | N=60 --> 40 | Trial completion date: Dec 2017 --> Dec 2018

||||||||||  NN1213 / Novo Nordisk
Trial completion, Enrollment change, Trial completion date, Trial primary completion date:  Application of Trans Cranial Direct Current Stimulation for Executive Dysfunction After Traumatic Brain Injury (clinicaltrials.gov) -  Aug 9, 2018
P=N/A, N=8, Completed,  Sponsor: Loewenstein Hospital
Recruiting --> Active, not recruiting | N=60 --> 40 | Trial completion date: Dec 2017 --> Dec 2018 Recruiting --> Completed | N=90 --> 8 | Trial completion date: Dec 2017 --> Mar 2017 | Trial primary completion date: Dec 2017 --> Mar 2017

||||||||||  NN1213 / Novo Nordisk
Enrollment closed, Trial completion date, Trial primary completion date:  Comparison of Two Psycho-educational Family Group Interventions for Persons With SCI and Their Caregivers (clinicaltrials.gov) -  Aug 2, 2018
P=N/A, N=64, Active, not recruiting,  Sponsor: St. Luke's Rehabilitation Institute
Recruiting --> Completed | N=90 --> 8 | Trial completion date: Dec 2017 --> Mar 2017 | Trial primary completion date: Dec 2017 --> Mar 2017 Recruiting --> Active, not recruiting | Trial completion date: Mar 2018 --> Jun 2019 | Trial primary completion date: Mar 2018 --> Dec 2018

||||||||||  NN1213 / Novo Nordisk
Trial completion:  Power Over Pain (POP) Study (clinicaltrials.gov) -  Jun 27, 2018
P=N/A, N=177, Completed,  Sponsor: University of Washington
Recruiting --> Active, not recruiting | Trial completion date: Mar 2018 --> Jun 2019 | Trial primary completion date: Mar 2018 --> Dec 2018 Active, not recruiting --> Completed

|||||||||| Trial completion, Enrollment change, Trial completion date, Trial primary completion date: COST-TBI: Combined Transcranial Magnetic Stimulation and Cognitive Treatment in Blast Traumatic Brain Injury (clinicaltrials.gov) - Jun 14, 2018
P=N/A, N=15, Completed, Sponsor: Boston Medical Center
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=24 --> 15 | Trial completion date: Oct 2018 --> Nov 2017 | Trial primary completion date: May 2018 --> Nov 2017

|||||||||| Enrollment closed: POLAR-RCT: The Prophylactic Hypothermia Trial to Lessen Traumatic Brain Injury (clinicaltrials.gov) - Jun 6, 2018
P=N/A, N=511, Active, not recruiting, Sponsor: Australian and New Zealand Intensive Care Research Centre
Active, not recruiting --> Completed | N=24 --> 15 | Trial completion date: Oct 2018 --> Nov 2017 | Trial primary completion date: May 2018 --> Nov 2017 Recruiting --> Active, not recruiting

||||||||||  midazolam hydrochloride / Generic mfg.
Enrollment change:  A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function (clinicaltrials.gov) -  Jun 1, 2018
P4, N=1, Terminated,  Sponsor: Michigan State University
Recruiting --> Active, not recruiting N=30 --> 1

||||||||||  NN1213 / Novo Nordisk
Trial completion:  Microstructural Changes in the Brain During Recovery After Mild Traumatic Brain Injury (clinicaltrials.gov) -  May 30, 2018
P=N/A, N=44, Completed,  Sponsor: University of Aarhus
N=30 --> 1 Recruiting --> Completed

|||||||||| Trial completion, Trial primary completion date: Resistance Training and Testosterone After Spinal Cord Injury (clinicaltrials.gov) - May 3, 2018
P2/3, N=26, Completed, Sponsor: VA Office of Research and Development
Recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Dec 2016 --> Dec 2017



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